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Experimental study on pressure fluctuation characteristics of slug flow in horizontal curved tubes

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High Technology Letters 2017年第1期23卷 23-29页

作者：邓志安 xiao xue College of Petroleum Engineering Xi'an Shiyou UniversityXi'an 710065P.R.China

In order to study the pressure characteristics of slug flow in horizontal curved tubes,two kinds of curved tubes with central angle 45° and 90° respectively are studied,of which are with 0. 5m circumference and 26 mm inner diameter are used. When the superficial liquid velocity or the superficial gas velocity is constant,the pressure fluctuations and the probability distribution of the average velocity of slug flow are clear for all of the five experimental conditions. The results of experiment show that the pressure characteristics of slug flow in curved tubes have periodic fluctuations. With the rise of central angle,the period of pressure fluctuation is more obvious. The system pressure of the slug flow increases with the increasing of superficial liquid/gas velocity. Meanwhile,the probability distribution of pressure signal shows regularity,such as unimodal,bimodal or multimodal.

关键词： slug flow horizontal curved tube pressure fluctuations central angle

Selective 3-and 6-OH modification of (-)-clausenamide

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Chinese Chemical Letters 2011年第7期22卷 761-764页

作者： Jian Jun xue xiao Ming Yu Institute of Materia Medica Chinese Academy of Medical Sciences & Peking Union Medical College Beijing 100050 China

（-）-Clausenamide is a drug candidate under Phase I clinical trial for treatment of Alzheimer＇s disease （AD）. In order to elucidate the substituent related structure-activity relationship, six one-substituent modified （-）-clausenamide analogues were designed, and four of them, namely 3-O-methyl, 6-O-methyl, 3-des-hydroxyl and 6-des-hydroxyl analogues were prepared by selective 3- and 6- OH modification of （-）-clausenamide.

关键词： (-)-Clausenamide Derivatives Synthesis Alzheimer's disease

Therapeutic effects on spastic cerebral palsy in children Acupuncture and massage at the Shu and He acupoints versus routine acupoints

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Neural Regeneration Research 2008年第1期3卷 53-56页

作者： xue-feng Wang xiao-li Hu Department of Pediatrics Affiliated Hospital Liaoning University of Traditional Chinese Medicine Shenyang 110032 Liaoning ProvinceChina

BACKGROUND： Based on clinical findings and syndromes, it has been previously shown that therapeutic methods for cerebral palsy can be greatly improved by selecting fewer, but more accurate acupoints. Therefore, greater therapeutic efficacy for cerebral palsy could be obtained by selecting the five Shu acupoints, which are located at the qi-intersecting point of the twelve meridians below the elbow and knee. OBJECTIVE： To treat children with spastic cerebral palsy using acupuncture and massage at the Shu and He points through a combination of rehabilitative training, and to compare the effects with routine acupuncture and massage. DESIGN： A randomized controlled clinical trial. SETTING： Rehabilitation Center for Cerebral Palsy, Department of Pediatrics, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine. PARTICIPANTS： Sixty children with spastic cerebral palsy were selected from the Rehabilitation Center for Cerebral Palsy, Department of Pediatrics, Affiliated Hospital of Liaoning University of Traditional Chinese Medicine from May 2003 to February 2006. There were 38 boys and 22 girls, aged 10 months to 4 years old, muscle strength ranging from grade I to grade IV. The children were randomly divided into a treatment group （n =30） and a control group （n =30）. Informed consent for the therapeutic program was obtained from the relatives of all enrolled children. The study was approved by the Hospital＇s Ethical Committee. METHODS： All children were given exercise and occupational therapy based on standard treatments. （1） In the control group, the children were additionally treated with routine acupuncture and massage during the one-month basic rehabilitative training. The acupuncture needles were manipulated alternately at the acupoints of Jianyu, Shousanli, Binao, Hegu, Huantiao, Xuanzhong, and Biguan. They were treated once per day, 6 days a week, followed by one day of rest. The children＇s limbs were first massaged by pressing, stretching, rol

关键词： cerebral palsy Shu and He acupoints acupuncture massage

滨海刺芹愈伤组织提取物中4种多酚含量测定及抗氧化、抗炎活性研究

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日用化学工业（中英文） 2024年第1期54卷 57-64页

作者：肖雪张慧荣李硕雯李孙华郭苗苗李丽北京工商大学轻工科学与工程学院北京市植物资源开发重点实验室北京100048 安赛搏(重庆)生物技术有限公司重庆400700

采用热水回流法制备滨海刺芹愈伤组织提取物,基于高效液相色谱法建立同时测定滨海刺芹愈伤组织提取物中迷迭香酸、隐绿原酸、金丝桃苷、槲皮素-3-O-(6’’-O-乙酰基)-β-D-吡喃葡萄糖苷四种多酚含量的方法,测定提取物对DPPH自由基、ABT... 详细信息

采用热水回流法制备滨海刺芹愈伤组织提取物,基于高效液相色谱法建立同时测定滨海刺芹愈伤组织提取物中迷迭香酸、隐绿原酸、金丝桃苷、槲皮素-3-O-(6’’-O-乙酰基)-β-D-吡喃葡萄糖苷四种多酚含量的方法,测定提取物对DPPH自由基、ABTS自由基清除能力。同时通过CCK-8法检测筛选样品给药浓度,建立痤疮丙酸杆菌诱导HaCaT细胞炎症模型,评价其抗炎功效。结果表明,提取物中隐绿原酸含量最高,为5.23 mg/g;迷迭香酸、槲皮素-3-O-(6’’-O-乙酰基)-β-D-吡喃葡萄糖苷、金丝桃苷的含量依次为1.30,0.50,0.08 mg/g。提取物具有较好的抗氧化、抗炎能力,对DPPH自由基、ABTS自由基清除能力的IC_(50)值分别为0.3239,0.2965 mg/mL,对痤疮丙酸杆菌诱导的HaCaT细胞分泌IL-1β,IL-8也具有显著抑制作用(P<0.05)。

关键词：滨海刺芹高效液相色谱多酚抗氧化抗炎

数字技术创新与企业绿色全要素生产率——基于数字经济核心产业专利的经验证据

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产经评论 2024年第3期15卷 51-64页

作者：陈建硕薛小龙黄琼宇高鸿铭广州大学管理学院

“十四五”以来,数字技术已然成为企业发展的崭新引擎,其在提高企业经营绩效的同时,能否兼顾生产效率和绿色效益的协调统一?构建数字技术创新驱动企业绿色全要素生产率提升的分析框架,以2008—2021年中国制造业上市企业为样本进行实证... 详细信息

“十四五”以来,数字技术已然成为企业发展的崭新引擎,其在提高企业经营绩效的同时,能否兼顾生产效率和绿色效益的协调统一?构建数字技术创新驱动企业绿色全要素生产率提升的分析框架,以2008—2021年中国制造业上市企业为样本进行实证检验。分析结果显示:数字技术创新对企业绿色全要素生产率具有显著促进作用;数字技术创新主要通过提高运营管理效率和促进绿色化转型实现企业绿色全要素生产率的提升;数字化效率提升业、数字产品制造业和数字技术应用业专利对企业绿色全要素生产率提升具有明显的驱动效果;非高新技术企业、重污染企业和劳动密集型企业的数字技术创新活动对绿色全要素生产率提升的作用更强。因此,企业通过数字技术创新提高绿色全要素生产率应构建合理的数字技术研发投入结构,加强关键数字经济核心产业专利的应用,将专利战略与绿色经营理念相匹配。

关键词：数字技术创新绿色全要素生产率运营管理效率绿色化转型数字经济核心产业专利

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结合现场环境及植物物证推断死亡时间1例

法医学杂志 2024年第2期40卷 202-204页

作者：徐杰薛晓明王玉宝岳宇张阳张家港市公安局江苏张家港215600 南京警察学院刑事科学技术学院江苏南京210083

1案例1.1简要案情2020年2月24日,某市公安局指挥中心接到报警称,在某地高速公路北侧一桥下河道内发现一具尸体。1.2现场勘验及尸表检查尸体所在河道呈南北走向,尸体位于桥北侧4.14 m处,桥下河道中部水深78 cm,桥北侧46 m处有河坝阻断,... 详细信息

1案例1.1简要案情2020年2月24日,某市公安局指挥中心接到报警称,在某地高速公路北侧一桥下河道内发现一具尸体。1.2现场勘验及尸表检查尸体所在河道呈南北走向,尸体位于桥北侧4.14 m处,桥下河道中部水深78 cm,桥北侧46 m处有河坝阻断,桥南侧150 m处有渔网隔离,水体呈静态。河道西侧为香樟树林,东侧岸边为杨树林。桥南侧东岸至高速公路及高速公路两侧均装有围栏;桥东西两端均有砖砌成的矮墙阻止汽车通行,桥西侧为乡道,向西可通公路。尸体距东侧河岸56 cm,呈仰卧位,该处水深28 cm,尸体下方及四周长有水草。尸体东侧岸边有一块2.5 m×2.1 m的平坦地面,地面散落有枯萎的杨树落叶及枯树枝。

关键词：法医病理学死亡时间推断水中尸体植物物证现场环境

ChatGPT Chats on Computational Experiments:From Interactive Intelligence to Imaginative Intelligence for Design of Artificial Societies and Optimization of Foundational Models

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IEEE/CAA Journal of Automatica Sinica 2023年第6期10卷 1357-1360页

作者： xiao xue Xiangning Yu Fei-Yue Wang College of Intelligence and Computing Tianjin UniversityTianjin 300350China State Key Laboratory for Management and Control of Complex Systems the Institute of Automdtion of Chinese Academg of SciencesBeijing 100190China

POWERED by the rapid development of Internet,the penetration of the Internet of Things,the emergence of big data,and the rise of social media,more and more complex systems are exhibiting the characteristics of social,physical,and information *** systems are known as cyber-physicalsocial systems(CPSS)[1],[2].These CPSS face unprecedented challenges in design,analysis,management,control and integration due to their involvement with human and social factors[3],[4].To cope with this challenge,there are two main approaches to CPSS research.

关键词： Intelligence Foundation involvement

Theoretical Study on the Intermolecular Interactions of Tetrazole Dimers

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Chinese Journal of Structural Chemistry 2005年第10期24卷 1203-1210页

作者： ZHOU Su-Qin JU xue-Hai xiao He-Ming Department of Chemistry Nanjing University of Science and Technology Nanjing 210094 China

Tetrazole monomers （Ⅰ, Ⅱ） and all of their possible stable dimers （1, 2, 3, 4, 5, 6, 7 and 8） were fully optimized by DFT method at the B3LYP/6-311＋＋G^＊＊ level. Among the eight dimers, there were two 1H-tetrazole dimers, three 2H-tetrazole dimers and three hetero dimers of 1H-tetrazole and 2H-tetrazole. Vibrational frequencies were calculated to ascertain that each structure was stable （no imaginary frequencies）. The basis set superposition errors （BSSE） are 2.78, 2.28, 2.97, 2.75, 2.74, 2.18, 1.23 and 3.10 kJ/mol, and the zero point energy （ZPE） corrections for the interaction energies are 4.88, 4.18, 3.87, 3.65, 3.54, 3.22, 2.87 and 4.34 kJ/mol for 1, 2, 3, 4, 5, 6, 7 and 8, respectively. After BSSE and ZPE corrections, the greatest corrected intermolecular interaction energy of the dimers is -43.71 kJ/mol. The charge redistribution mainly occurs on the adjacent N-H…N atoms between submolecules. The charge transfer between two subsystems is very small. Natural bond orbital （NBO） analysis was performed to reveal the origin of the interaction. Based on the statistical thermodynamic method, the standard thermodynamic functions, heat capacities （C^0P）, entropies （S^0T） and thermal corrections to enthalpy （H^0T）, and the changes of thermodynamic properties from monomer to dimer in the temperature range of 200.00 K to 700 K have been obtained. 1H-tetrazole monomer can spontaneously turn into two stable dimers at 298.15 K.

关键词： tetrazole dimer intermolecular interaction DFT natural bond orbital,thermodynamic properties

“跟着书本去旅行”校本课程开发与实施——以“跟着初中语文课本观大河风光”为例

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当代教研论丛 2024年第9期10卷 62-65页

作者：王贞月崔晓雪山东省滨州经济技术开发区中海中学(滨州实验学校西校区) 山东滨州256606

新一轮课程改革的背景下,培养学生的创新精神和实践能力成为教育的核心目标。校本课程作为我国现代教育体系的重要组成部分,正面临新的挑战。当前形势下,探讨如何在校本课程中实现项目化学习与跨学科、大单元教学的融合,以及在促进学生... 详细信息

新一轮课程改革的背景下,培养学生的创新精神和实践能力成为教育的核心目标。校本课程作为我国现代教育体系的重要组成部分,正面临新的挑战。当前形势下,探讨如何在校本课程中实现项目化学习与跨学科、大单元教学的融合,以及在促进学生个性化发展的同时展现学校特色,显得尤为关键。文章以“跟随初中语文课本游览大河风光”为例,深入研究了“跟着书本去旅行”校本课程的开发与应用,旨在为中学阶段校本课程的创新开发与教学实践提供借鉴和参考。

关键词： “跟着书本去旅行” 校本课程初中语文课本黄河文化