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Immunotherapy for hepatobiliary malignancies:Progress and prospective

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Hepatobiliary & Pancreatic Diseases International 2022年第5期21卷 409-412页

作者： Lun-xiu Qin Department of General Surgery Huashan HospitalFudan UniversityShanghai 200040China

Hepatobiliary malignancies include hepatocellular carcinoma(HCC)and biliary tract cancers(BTCs).They are characterized by high heterozygosity,rapid progression,and difflcult to treat[1,2].Recent rapid progress in targeted therapeutic agents has brought new hope for those with advanced HCC[3-5].But there are problems such as lower response rate,or drug resistance(primary or acquired),as well as poor tolerance due to their side-effects,which make this treatment alone still face great challenges.

关键词： biliary malignancies prospective

FINITE ELEMENT METHODS FOR THE NAVIER-STOKES EQUATIONS BY H(div)ELEMENTS

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Journal of Computational Mathematics 2008年第3期26卷 410-436页

作者： Junping Wang Xiaoshen Wang xiu Ye Division of Mathematical Sciences National Science Foundation Arlington VA 22230 USA Department of Mathematics University of Arkansas at Little Rock Little Rock AK 72204 USA

We derived and analyzed a new numerical scheme for the Navier-Stokes equations by using H（div） conforming finite elements. A great deal of effort was given to an establishment of some Sobolev-type inequalities for piecewise smooth functions. In particular, the newly derived Sobolev inequalities were employed to provide a mathematical theory for the H（div） finite element scheme. For example, it was proved that the new finite element scheme has solutions which admit a certain boundedness in terms of the input data. A solution uniqueness was also possible when the input data satisfies a certain smallness condition. Optimal-order error estimates for the corresponding finite element solutions were established in various Sobolev norms. The finite element solutions from the new scheme feature a full satisfaction of the continuity equation which is highly demanded in scientific computing.

关键词： Finite element methods Navier-Stokes equations CFD

Integral—Type Darboux Transformations for the mKdV Hierarchy with Self—COnsistent Sources

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Communications in Theoretical Physics 2002年第6X期38卷 641-648页

作者： ZENGYun-Bo MAWen-xiu 等 DepartmentofMathematicalSciences TsinghuaUniveersityBeijing100084China DepartmentofMathematics CityUniversityofHongKongKowloonHongKongChina

We present integral-type Darboux transformation for the mKdV hierarchy and for the mKdV hierarchy withself-consistent sources. In contrast with the normal Darboux transformation, the integral-type Darboux transformationscan offer non-auto-Backlund transformation between two (2n + 1)-th mKdV equations with self-consistent sources withdifferent degrees. This kind of Darboux transformation enables us to construct the N-soliton solution for the mKdVhierarchy with self-consistent sources. We also propose the formulas for the m times repeated integral-type Darbouxtransformations for both mKdV hierarchy and mKdV hierarchy with self-consistent sources.

关键词：孤子方程积分型Darboux变换自洽源非线性偏微分方程

Potential Effects of the COVID-19 Pandemic on the Developing Brain

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Neuroscience Bulletin 2023年第2期39卷 343-347页

作者： Xiang Yu xiu Xu State Key Laboratory of Membrane Biology School of Life SciencesPeking-Tsinghua Center for Life Sciencesand Peking University McGovern InstitutePeking UniversityBeijing 100871China Autism Research Center of Peking University Health Science Center Beijing 100191China Chinese Institute for Brain Research Beijing 102206China Department of Child Healthcare Children’s Hospital of Fudan UniversityShanghai 201102China

By now,the COVID-19 pandemic has affected all corners of the world for over two *** years constitutes 4%of the life experience of a 50-year-old,or 50%of the life experience of a ***,in terms of the sheer proportion of... 详细信息

关键词： has she ID

Predicting CircRNA-Disease Associations Based on Improved Weighted Biased Meta-Structure

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Journal of Computer Science & Technology 2021年第2期36卷 288-298页

作者： xiu-Juan Lei Chen Bian Yi Pan School of Computer Science Shaanxi Normal UniversityXi'an 710119China School of Computer Science and Control Engineering Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhen 518055China Department of Computer Science Georgia State UniversityAtlantaGA 30302U.S.A

Circular RNAs(circRNAs)are RNAs with a special closed loop structure,which play important roles in tumors and other *** to the time consumption of biological experiments,computational methods for predicting associations between circRNAs and diseases become a better *** the limited number of verified circRNA-disease associations into account,we propose a method named CDWBMS,which integrates a small number of verified circRNA-disease associations with a plenty of circRNA information to discover the novel circRNA-disease *** adopts an improved weighted biased meta-structure search algorithm on a heterogeneous network to predict associations between circRNAs and *** terms of leave-one-out-cross-validation(LOOCV),10-fold cross-validation and 5-fold cross-validation,CDWBMS yields the area under the receiver operating characteristic curve(AUC)values of 0.9216,0.9172 and 0.9005,***,case studies show that CDWBMS can predict unknow circRNA-disease *** conclusion,CDWBMS is an effective method for exploring disease-related circRNAs.

关键词： circular RNA(circRNA) circRNA-disease association meta-structure heterogeneous network

LUMP AND INTERACTION SOLUTIONS TO LINEAR (4+1)-DIMENSIONAL PDES

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Acta Mathematica Scientia 2019年第2期39卷 498-508页

作者： Wen-xiu MA College of Mathematics and Physics Shanghai University of Electric Power Department of Mathematics King Abdulaziz University Department of Mathematics and Statistics University of South Florida Department of Mathematics Zhejiang Normal University College of Mathematics and Systems Science Shandong University of Science and Technology International Institute for Symmetry Analysis and Mathematical Modelling Department of Mathematical Sciences North-West University Mafikeng Campus

Taking a class of linear(4+1)-dimensional partial differential equations as examples, we would like to show that there exist lump solutions and interaction solutions in(4+1)-dimensions. We will compute abundant lump solutions and interaction solutions to the considered linear(4+1)-dimensional partial differential equations via symbolic computations,and plot three specific solutions with Maple plot tools, which supplements the existing literature on lump, rogue wave and breather solutions and their interaction solutions in soliton theory.

关键词： symbolic computation lump solution: interaction solution

Controlled Coherent Quantum Tunneling of Atomic Ensembles

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Communications in Theoretical Physics 2003年第1期39卷 109-111页

作者： MIAOYuan－xiu LIYong CenterforAdvancedStudy TsinghuaUniversityBeijing100084China InstituteofTheoreticalPhysics theChineseAcademyofAciencesBeijing100080China

We investigate the coherent tunneling phenomenon of the laser-driven atomic ensembles confined in a well-separated double-well potential. By generalizing the Frohlich canonical transformation to adiabatically eliminate the light field variable, a BCS-like effective Hamiltonian is obtained to depict the residual interaction between the two atomic ensembles. The number of the tunneling collective low excitations and its relationship to the ratios gr/gl and Nr/Nl are given.

关键词： atomic ensemble coherence tunneling

Metallic nonstoichiometric WO_(3-x)-decorated NiFe-layered double hydroxide for boosted urea electro-oxidation reaction:the facilitated dynamics and increasing active sites

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Tungsten 2024年第4期6卷 663-668页

作者： Hai-Long Liao xiu-Lin Wu xiu-Juan Sun College of Chemistry Xiangtan UniversityXiangtan411105China Key Laboratory of Environmentally Friendly Chemistry and Applications of Ministry of Education Xiangtan UniversityXiangtan411105China

Clean hydrogen production based on pure water electrolysis has been considered a potential way to solve the energy crisis and serious environmental ***,the disadvantaged high reaction potential of anodic oxygen evolut... 详细信息

关键词： hydroxide layered disadvantage

Bi-Hamiltonian Structure of a Third-Order Nonlinear Evolution Equation on Plane Curve Motions

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Communications in Theoretical Physics 2007年第2X期48卷 211-214页

作者： REN Wen-xiu Alatancang Department of Mathematics Inner Mongolia University Hohhot 010021 China Department of Mathematics Inner Mongolia University of Technology Hohhot 010051 China

In the present paper, we identify the integrability of the third-order nonlinear evolution equation ut = （1/2）（（uxz ＋ u）^-2）z in a Hamiltonian viewpoint. We prove that the recursion operator obtained by ***. Sakovich is hereditary, and then deduce a bi-Hamiltonian structure of the equation by using some decomposition of the hereditary operator. A hierarchy associated to the equation is also shown.

关键词： nonlinear evolution equation bi-Hamiltonian structure hereditary operator integrability