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Driver Steering Behaviour Modelling Based on Neuromuscular Dynamics and Multi‑Task Time‑Series Transformer

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Automotive Innovation 2024年第1期7卷 45-58页

作者： Yang xing Zhongxu Hu Xiaoyu Mo Peng Hang Shujing Li Yahui Liu Yifan zhao Chen Lv School of Aerospace Transport and ManufacturingCranfield UniversityCranfield MK430ALUnited Kingdom School of Mechanical and Aerospace Engineering Nanyang Technological UniversitySingapore 639798Singapore College of Transportation Engineering Tongji UniversityShanghai 200092China College of Computer Science and Technology Jilin UniversityChangchun 130012China School of Vehicle and Mobility Tsinghua UniversityBeijing 100084China

Driver steering intention prediction provides an augmented solution to the design of an onboard collaboration mechanism between human driver and intelligent *** this study,a multi-task sequential learning framework is developed to pre-dict future steering torques and steering postures based on upper limb neuromuscular electromyography *** joint representation learning for driving postures and steering intention provides an in-depth understanding and accurate modelling of driving steering *** different testing scenarios,two driving modes,namely,both-hand and single-right-hand modes,are *** each driving mode,three different driving postures are further ***,a multi-task time-series transformer network(MTS-Trans)is developed to predict the future steering torques and driving postures based on the multi-variate sequential input and the self-attention *** evaluate the multi-task learning performance and information-sharing characteristics within the network,four distinct two-branch network architectures are *** validation is conducted through a driving simulator-based experiment,encompassing 21 *** pro-posed model achieves accurate prediction results on future steering torque prediction as well as driving posture recognition for both two-hand and single-hand driving *** findings hold significant promise for the advancement of driver steering assistance systems,fostering mutual comprehension and synergy between human drivers and intelligent vehicles.

关键词： Driver steering behaviours Neuromuscular dynamics Multi-task learning Sequential transformer Intelligent vehicles

Root-derived long-distance signals trigger ABA synthesis and enhance drought resistance in Arabidopsis

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Journal of Genetics and Genomics 2024年第7期51卷 749-761页

作者： Qian-Qian Liu Jin-Qiu Xia Jie Wu Yi Han Gui-quan Zhang Ping-Xia zhao Cheng-Bin Xiang Division of Life Sciences and Medicine Division of Molecular&Cell BiophysicsHefei National Science Center for Interdisciplinary Sciences at the MicroscaleUniversity of Science and Technology of ChinaThe Innovation Academy of Seed DesignChinese Academy of SciencesHefeiAnhui 230027China College of Life Sciences Anhui Agricultural UniversityHefeiAnhui 230036China College of Agronomy South China Agricultural UniversityGuangzhouGuangdong 510642China School of Biology and Basic Medical Sciences Soochow UniversitySuzhouJiangsu 215123China

Vascular plants have evolved intricate long-distance signaling mechanisms to cope with environmental stress,with reactive oxygen species(ROS)emerging as pivotal systemic signals in plant stress ***,the exact role of ROS as root-to-shoot signals in the drought response has not been *** this study,we reveal that compared with wild-type plants,ferric reductase defective 3(frd3)mutants exhibit enhanced drought resistance concomitant with elevated NINE-CIS-EPOXYCAROTENOID DIOXYGENASE 3(NCED3)transcript levels and abscisic acid(ABA)contents in leaves as well as increased hydrogen peroxide(H_(2)O_(2))levels in roots and *** experiments distinctly illustrate that drought resistance can be conferred by the frd3 rootstock regardless of the scion genotype,indicating that long-distance signals originating from frd3 roots promote an increase in ABA levels in ***,the drought resistance conferred by the frd3 mutant rootstock is weakened by the CAT2-overexpressing scion,suggesting that H_(2)O_(2)may be involved in long-distance ***,the results of comparative transcriptome and proteome analyses support the drought resistance phenotype of the frd3 *** together,our findings substantiate the notion that frd3 root-derived long-distance signals trigger ABA synthesis in leaves and enhance drought resistance,providing new evidence for root-to-shoot long-distance signaling in the drought response of plants.

关键词： frd3 Drought resistance Root-to-shoot long-distance signals Reactive oxygen species(ROS) H_(2)O_(2) Iron ABA

Preparation and performance evaluation of the slickwater using novel polymeric drag reducing agent with high temperature and shear resistance ability

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Petroleum Science 2024年第2期21卷 1113-1121页

作者： Ming-Wei zhao Zhen-Feng Ma Cai-Li Dai WeiWu Yong-quan Sun Xu-Guang Song Yun-Long Cheng Xiang-Yu Wang National Key Laboratory of Deep Oil and Gas China University of Petroleum(East China)Qingdao266580ShandongChina Shandong Key Laboratory of Oilfield Chemistry China University of Petroleum(East China)Qingdao266580ShandongChina Sinopec Shengli Oilfield Dongying257001ShandongChina Department of Chemical and Materials Engineering University of AlbertaEdmontonAB T6G 1H9Canada East China Petroleum Bureau of Sinopec Nanjing210011JiangsuChina

Slickwater fracturing fluids are widely used in the development of unconventional oil and gas resources due to the advantages of low cost,low formation damage and high drag reduction ***,their performance is severely affected at high *** reducing agent is the key to determine the drag reducing performance of *** this work,in order to further improve the temperature resistance of slickwater,a temperature-resistant polymeric drag reducing agent(PDRA)was synthesized and used as the basis for preparing the temperature-resistant *** slickwater system was prepared with the compositions of 0.2 wt%PDRA,0.05 wt%drainage aid nonylphenol polyoxyethylene ether phosphate(NPEP)and 0.5 wt%anti-expansion agent polyepichlorohydrindimethylamine(PDM).The drag reduction ability,rheology properties,temperature and shear resistance ability,and core damage property of slickwater were systematically studied and *** contrast to on-site drag reducing agent(DRA)and HPAM,the temperature-resistant slickwater demonstrates enhanced drag reduction efficacy at 90℃,exhibiting superior temperature and shear resistance ***,the drag reduction retention rate for the slickwater achieved an impressive 90.52%after a 30-min shearing ***,the core damage is only 5.53%.We expect that this study can broaden the application of slickwater in high-temperature reservoirs and provide a theoretical basis for field applications.

关键词： Unconventional resources Polymeric drag reducing agent Slickwater High drag reduction rate Temperature resistance

Dynamically switchable porphyrin-based molecular tweezer for on-off fullerene recognition

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Chinese Chemical Letters 2024年第6期35卷 283-287页

作者： Zhimin Sun Xin-Hui Guo Yue zhao Qing-Yu Meng Li-Juan xing He-Lue Sun College of Chemistry and Materials Science Hebei Key Laboratory of Organic Functional MoleculesHebei Normal UniversityShijiazhuang 050024China

Herein,a novel molecular tweezer based on 2,2'-bipyridine-bridged porphyrin subunits was constructed for efficient fullerenes *** syn conformation of the molecule,which was obtained by Zn(Ⅱ)coordination,gives rise to a proper cavity to interact with fullerene guests to form a stable 1:1 complex in toluene *** exhibits distinct binding selectivity towards C_(60)over C_(70).Moreover,the fullerene recognition capacity can be adequately suppressed by importing H_(2)PO_(4)^(-)to competitively capture Zn(Ⅱ)along with syn-anti conformational ***,the molecular tweezer regenerated to bind the fullerene by introducing the Ca^(2+)into the ***,the association-disassociation process can be switched reversibly and repeatedly.

关键词： Molecular tweezer Fullerene recognition Supramolecular chemistry Conformation conversion Coordination

Influence of sintering time on microstructure and properties of hot oscillatory pressing sintered W–Cu refractory alloys

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Tungsten 2024年第2期6卷 323-332页

作者： Zi-Qian Wu Wei zhao Ka Gao Shi-Hao Du Qing-quan Kong De-Jian Sun Yang Gao School of Materials Science and Engineering Zhengzhou University of AeronauticsZhengzhou 450015China School of Mechanical Engineering University of Shanghai for Science and TechnologyShanghai 200093China Department of General Medicine Changhai HospitalShanghai 200000China Hubei Key Laboratory of Mechanical Transmission and Manufacturing Engineering Wuhan University of Science and TechnologyWuhan 430081China Sichuan Province Engineering Technology Research Center of Powder Metallurgy Chengdu UniversityChengdu 610106China

W–Cu refractory alloys are widely used in aerospace,aviation,electronics,power,and other fi ***,because of its large melting point diff erence between alloy elements,the conventional powder metallurgy method required a long time of high temperature sintering is very likely to cause low density and abnormal grain size ***,90W-10Cu refractory alloys were successfully prepared by hot oscillatory pressing(HOP)under diff erent sintering time in this *** the infl uence of sintering time on the microstructure,grain size,density,Vickers hardness,room-tensile property,and electrical conductivity of the W–Cu refractory alloy was systematically *** results showed that during the short sintering time(30–90 min),the density,Vickers hardness,tensile strength,and electrical conductivity of the W–Cu refractory alloy increased signifi cantly to 98.7%,163.29 HV 30,507.3 MPa,and 14.2%International Annealed Copper Standard with the sintering time increasing,respectively,while its grain size showed no obvious *** the sintering time further increased to 120 min,the density was basically consistent with the sintering time of 90 ***,the prolonged high temperature sintering resulted in the grain growth of the samples,which caused the deterioration of the Vickers hardness,room-tensile strength,and conductivity properties of the W–Cu refractory *** the same sintering time,the density,Vickers hardness,and electrical conductivity of the HOP sintered W–Cu refractory alloy were signifi cantly higher than those of the HP sintered *** was indicated that high density,fi ne-grain,and excellent properties W–Cu refractory alloys could be prepared by hot oscillatory pressing under appropriate sintering time.

关键词： W–Cu refractory alloy Hot oscillatory pressing Sintering time Microstructure Property

Numerical evaluations on the fluid production in the in-situ conversion of continental shale oil reservoirs

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Petroleum Science 2024年第4期21卷 2485-2501页

作者： zhao-Bin Zhang Maryelin Josefina Brice?o Montilla Shou-Ding Li Xiao Li Jian-Peng xing Yan-Zhi Hu Key Laboratory of Shale Gas and Geoengineering Institute of Geology and Geophysics Chinese Academy of Sciences Institute of Earth Sciences Chinese Academy of Sciences College of Earth and Planetary Sciences University of Chinese Academy of Sciences Institute of Energy Peking University

In-situ conversion presents a promising technique for exploiting continental oil shale formations,characterized by highly fractured organic-rich rock. A 3D in-situ conversion model, which incorporates a discrete fracture network, is developed using a self-developed thermal-flow-chemical(TFC) *** of the model elucidates the in-situ conversion process in three stages and defines the transformation of fluids into three distinct outcomes according to their end stages. The findings indicate that kerogen decomposition increases fluid pressure, activating fractures and subsequently enhancing permeability. A comprehensive analysis of activated fracture permeability and heating power reveals four distinct production modes, highlighting that increasing heating power correlates with higher cumulative fluid production. Activated fractures, with heightened permeability, facilitate the mobility of heavy oil toward production wells but hinder its cracking, thereby limiting light hydrocarbon ***, energy efficiency research demonstrates the feasibility of the in-situ conversion in terms of energy utilization, especially when considering the surplus energy from high-fluctuation energy sources such as wind and solar power to provide heating.

关键词： In-situ conversion Continental shale oil Natural fracture network TFC model

Mechanical performance of 22SiMn2TiB steel welded with lowtransformation- temperature filler wire and stainless steel filler wire

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Journal of Iron and Steel Research International 2024年第4期31卷 967-981页

作者： Zi-dong Lin Kai-jie Song Zhen Sun Zi-qian Zhu Xue-feng zhao Constantinos Goulas Wei Ya xing-hua Yu School of Materials Science and Engineering Beijing Institute of TechnologyBeijing 100081China Beijing Institute of Technology Chongqing Innovation Center Chongqing 401120China Department of Design Production and Management Faculty of Engineering Technology.University of TwenteEnschede 7500 AETheNetherlands Rotterdam Additive Manufacture Fieldlab(RAMLAB) Rotterdam 3089 JWTheNetherlands

TX-80 low-transformation-temperature(LTT)welding wire was used to replace the traditional ER 307Si welding wire to realize the connection of 22SiMn2TiB armor steel in manual overlay *** previously existing issues,such as welding cracks,large welding deformation,and severe welding residual stress,were solved to ensure good strength and ductility *** particular,with the same welding conditions,TX-80 LTT wire eliminates welding *** reduces the welding deformation no matter the base pretreatment of pre-setting angle or no pre-setting *** comparison,it was found that the microstructure at the TX-80 weld is mainly composed of martensite and a small amount of retained *** contrast,the microstructure of the ER 307Si weld consists of a large amount of austenite and a small amount of skeleton-like *** variation trend of residual stress and microhardness from the weld to the base were investigated and compared with the mechanical properties of base *** TX-80 and the ER 307Si tensile samples elongation is 6.76%and 6.01%,while the ultimate tensile strengths are 877 and 667 MPa,*** average impact toughness at room temperature of the ER 307Si weld is 143.9 J/cm^(2),much higher than that of the TX-80 weld,which is only 36.7 J/cm^(2).The relationship between impact and tensile properties with microstructure species and distribution was *** addition,the fracture surface of the tensile and the impact samples was observed and *** dimples,fewer pores,larger radiation zone,and shear lips of TX-80 samples indicate better tensile ductility and worse impact toughness than those of ER 307Si weld.

关键词： Low-transformation-temperature material 22SiMn2TiB steel Welding deformation Residual stress Martensitic transformation Mechanical property

Prediction model establishment and validation for enteral nutrition aspiration during hospitalization in patients with acute pancreatitis

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World Journal of Gastrointestinal Surgery 2024年第8期16卷 2583-2591页

作者： Ping Hou Hao-Jun Wu Tang Li Jia-Bin Liu quan-Qing zhao Hong-Jiang zhao Zi-Ming Liu Division II of General Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Division of Biliary Tract Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Hepatobiliary and Pancreatic Surgery West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Department of Thyroid Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina Department of Oncology West China Hospital-Chengdu Shangjin NanfuWest China HospitalSichuan UniversityChengdu 611730Sichuan ProvinceChina Division of Biliary Tract Surgery Department of General SurgeryWest China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Acute pancreatitis(AP)is a disease caused by abnormal activation of pancreatic enzymes and can lead to self-digestion of pancreatic tissues and dysfunction of other *** nutrition plays a vital role in the treatment of AP because it can meet the nutritional needs of patients,promote the recovery of intestinal function,and maintain the barrier and immune functions of the ***,the risk of aspiration during enteral nutrition is high;once aspiration occurs,it may cause serious complications,such as aspiration pneumonia,and suffocation,posing a threat to the patient’s *** study aims to establish and validate a prediction model for enteral nutrition aspiration during hospitalization in patients with *** To establish and validate a predictive model for enteral nutrition aspiration during hospitalization in patients with *** A retrospective review was conducted on 200 patients with AP admitted to Chengdu Shangjin Nanfu Hospital,West China Hospital of Sichuan University from January 2020 to February *** data were collected from the electronic medical record *** were randomly divided into a validation group(n=40)and a modeling group(n=160)in a 1:4 ratio,matched with 200 patients from the same time *** modeling group was further categorized into an aspiration group(n=25)and a non-aspiration group(n=175)based on the occurrence of enteral nutrition aspiration during *** and multivariate logistic regression analyses were performed to identify factors influencing enteral nutrition aspiration in patients with AP during hospitalization.A prediction model for enteral nutrition aspiration during hospitalization was constructed,and calibration curves were used for *** operating characteristic curve analysis was conducted to evaluate the predictive value of the *** There was no statistically significant difference in general data between the validation and mode

关键词： Acute pancreatitis Hospitalization Enteral nutrition Predictive model Aspiration

B-cell-specific signatures reveal novel immunophenotyping and therapeutic targets for hepatocellular carcinoma

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World Journal of Gastroenterology 2024年第34期30卷 3894-3925页

作者： Ke-quan Xu Zheng Gong Jia-Ling Yang Chu-Qi Xia Jian-Yi zhao Xi Chen Department of Hepatobiliary and Pancreatic Surgery Zhongnan Hospital of Wuhan UniversityWuhan 430071Hubei ProvinceChina Department of Pharmacy Union HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan 430022Hubei ProvinceChina School of Basic Medical Sciences Nanjing Medical UniversityNanjing 211166Jiangsu ProvinceChina Department of Gastrointestinal Surgery The Second Affiliated Hospital of Kunming Medical UniversityKunming 650101Yunnan ProvinceChina Department of General Surgery Second People’s Hospital of Jiaozuo CityJiaozuo 454001Henan ProvinceChina

BACKGROUND Immunotherapy presents both promises and challenges in treating hepatocellular carcinoma(HCC)due to its complex immunological *** role of B cells,a key part of the immune system,remains uncertain in *** To identify B-cell-specific signatures and reveal novel immunophenotyping and therapeutic targets for *** Using the Tumor Immune Single-cell Hub 2 database,we identified B-cell-related genes(BRGs)in *** enrichment analysis was performed to explore the possible collaboration between B cells and T cells in *** conducted univariate Cox regression analysis using The Cancer Genome Atlas liver HCC collection dataset to find BRGs linked to HCC ***,least absolute shrinkage and selection operator regression was utilized to develop a prognostic model with 11 *** model was validated using the International Cancer Genome Consortium dataset and *** The risk score derived from the prognostic model emerged as an independent prognostic factor for *** of the immune microenvironment and cell infiltration revealed the immune status of various risk groups,supporting the cooperation of B and T cells in suppressing *** BRGs model identified new molecular subtypes of HCC,each with distinct immune *** sensitivity analysis identified targeted drugs effective for each HCC subtype,enabling precision therapy and guiding clinical *** We clarified the role of B cells in HCC and propose that the BRGs model offers promising targets for personalized immunotherapy.

关键词： B cell Hepatocellular carcinoma Immune microenvironment Immunotherapy Molecular subtype