检索结果-南通市图书馆

Stimuli-evoked NOergic molecules and neuropeptides at acupuncture points and the gracile nucleus contribute to signal transduction of propagated sensation along the meridian through the dorsal medulla-thalamic pathways

引用

Journal of Integrative Medicine 2024年第5期22卷 515-522页

作者： Sheng-xing ma Lundquist Institute for Biomedical Innovation Harbor-University of California at Los Angeles(UCLA)Medical CenterTorranceCA 90502USA Department of Obstetrics and Gynecology David Geffen School of Medicine at UCLA and Harbor-UCLA Medical CenterTorranceCA 90502USA

Numerous studies from different international groups have demonstrated that sensations can be propagated along acupuncture channel *** propagated sensation along the channel pathway(PSCP)can be elicited by electroacupuncture(EA),transcutaneous electrical nerve stimulation(TENS),manual acupuncture(ma),and heat applied to distal acupuncture points(acupoints).Nitric oxide(NO)levels were reported to be elevated in the gracile nucleus and skin regions near to the EA sites,with higher levels at acupoints associated with an enhanced expression of NO synthase and transient receptor potential vanilloid type *** stimuli,EA,ma,TENS,and heat,have been used to elicit axonal reflexes,which increase local release of NO and neuropeptides such as calcitonin gene related ***,the sensation of PSCP along the body surface occurs only ipsilaterally to the stimulated acupoints in various human studies,which does not support the involvement of the spinal-thalamic pathway,which would involve cross over transmission of the *** gracile nucleus receives ascending input from the sciatic nerve and responds to somatosensory stimulation mainly on the ipsilateral side via the dorsal column *** at Zusanli(ST36)increases NO release and expression of NO synthase mainly in the ipsilateral side of the gracile nucleus,while the cardiovascular effects and analgesic responses to EA at ST36 are changed by influences of l-arginine-derived NO synthesis in the ipsilateral gracile nucleus in *** stimuli-induced release of NOergic molecules and neuropeptides exist high levels in the acupoints,which contain rich neuronal components and blood *** NOergic molecules at acupoints cause axon reflexes during the stimuli,which elevate cutaneous blood *** NOergic molecules and local blood flow may spread over acupoints one after another along the meridian lines differing from nerve pathways following the stimuli to induce *** same types of stimula

关键词： Axon reflex Nitric oxide Biophysical approaches Calcitonin related polypeptide Dorsal funiculus tract Meridian system

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Wnt pathway antagonists and angiogenesis

引用

Protein & Cell 2010年第10期1卷 898-906页

作者： Bin Zhang Jian-xing ma Department of Physiology Department of MedicineThe University of Oklahoma Health Sciences CenterOklahoma CityOk 73104USA

Dysregulation of the Wnt pathway has been extensively studied in multiple diseases,including some angiogenic *** signaling activation is a major stimulator in pathological angiogenesis and thus,Wnt antagonists are believed to have therapeutic potential for neovascular ***,some Wnt antagonists have been identified directly from the anti-angiogenic factor *** review summarizes the recent progress toward understanding of the roles of Wnt pathway antagonists in angiogenic regulation and their mechanism of action,and exploring their therapeutic potential.

关键词： sFRPs Dkk WIF-1 endostatin SERPINA3K curcumin

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Nanomaterial Labels in Lateral Flow Immunoassays for Point-of-Care-Testing

引用

Journal of materials Science & Technology 2021年第1期60卷 90-104页

作者： Jiuchuan Guo Shuqin Chen Jinhong Guo xing ma School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 610054China Flexible Printed Electronic Technology Center&School of materials Science and Engineering Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Shenzhen Bay Laboratory No.9 Duxue RoadShenzhen 518055China

Lateral flow immunoassays(LFIAs) have been developed rapidly in recent years and used in a wide range of application at point-of-care-testing(POCT),where small biomolecules can be conveniently examined on a test *** with other biochemical detection methods such as ELISA(enzyme linked immunosorbent assay) or mass spectrometry method,LFIAs have the advantages of low cost,easy operation and short ***,it suffers from low sensitivity since conventional LFIA can only realize qualitative detection based on colorimetric *** the increasing demand for more accurate and sensitive determination,novel nanomaterials have been used as labels in LFIAs due to their unique advantages in physical and chemical *** gold,fluorescent nano particles,SERSactive nanomaterials,magnetic nanoparticles and carbon nanomaterials are utilized in LFIAs to produce different kinds of signals for quantitative or semi-quantitative *** review paper first gives a description of the LFIA principles,and then focuses on the state-of-the-art nanomaterial labelling technology in *** last,the conclusion and outlook are given to inspire exploration of more advanced nanomaterials for the development of future LFIAs.

关键词： lateral flow immunoassays(LFIA) point-of-care-testing(POCT) nanomaterial labelling technology quantitative detection

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

C:N:P stoichiometry of perennial herbs’ organs in the alpine steppe of the northern Tibetan Plateau

引用

Journal of Mountain Science 2019年第9期16卷 2039-2047页

作者： ma xing-xing HONG Jiang-tao WANG Xiao-dan College of Geographical Sciences Shanxi Normal University Linfen 041000 China Institute of Mountain Hazards and Environment Chinese Academy of Sciences Chengdu 610041 China

The patterns of C:N:P stoichiometry across ecosystems are important in understanding biogeochemical processes. The stoichiometry of nutrients at the leaf and root level have been reported previously, but relationships of other plant organs, such as stems and the reproductive organs, remain unclear. We collected 228 samples of leaves, roots, stems and reproductive organs from 11 common plant species at 25 sites on the Tibetan Plateau to explore the relationships of C:N:P stoichiometry both within and across plant organs. The average C concentrations in the roots, leaves, stems and reproductive organs were 427.32, 410.51, 421.11 and 416.72 mg g-1, respectively. The shoot tissues(leaves, stems and reproductive organs) had significantly higher N and P concentrations than the roots. The N and P concentrations had a significant positive correlation within the same organ. The nutrient concentrations(N and P) and nutrient ratios(C:N, C:P and N:P) were significantly correlated across all pairwise organ combinations. Our data suggest that alpine perennial herbs share similar evolutionary histories and have constrained patterns of covariation for C concentrations, with differential patterns for N and P stoichiometry across organs. Our data also indicate that covarying sets of nutrient traits are consistent across environments and biogeographical regions and demonstrate convergent evolution in plant nutritional characteristics in extreme alpine environments.

关键词： Shoot tissues Chemical elements Biogeochemical process Alpine steppe Tibet Plateau

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Preparation and application of microfluidic SERS substrate:Challenges and future perspectives

引用

Journal of materials Science & Technology 2020年第2期37卷 96-103页

作者： Jiuchuan Guo Fanyu Zeng Jinhong Guo xing ma School of Information and Communication Engineering University of Electronic Science and Technology of ChinaChengdu 610054China State Key Laboratory of Advanced Welding and Joining Harbin Institute of Technology(Shenzhen)Shenzhen 518055China Flexible Printed Electronic Technology Center School of Materials Science and EngineeringHarbin Institute of Technology(Shenzhen)Shenzhen 518055China

Surface-enhanced Raman spectroscopy(SERS),as a highly sensitive molecular analysis technique,can realize fast and non-destructive detection of the information of molecular bonds to identify the component of analytes by"fingerprint"*** preparation of SERS substrates plays an extremely important role in the development of SERS technology and the application of SERS *** integrating SERS enhancement substrates into microfluidic chips,researchers have developed the microfluidic SERS chips which expand the function of microfluidic chips and provide an efficient platform for on-site biochemical analysis equipped with the powerful sensing capability of SERS *** this paper,we will first briefly give a review of the current microfluidic SERS-active substrates preparation technology and present the perspective on the application prospects of microfluidic SERS-active *** then the challenges in the preparation of microfluidic SERS-active substrates will be pointed out,as well as realistic issues of using this technology for biochemical application.

关键词： SERS substrate Microfluidics Biochemical sensing On-site analysis

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Blind false data injection attacks in smart grids subject to measurement outliers

引用

Journal of Control and Decision 2022年第4期9卷 445-454页

作者： xing-Jian ma Huimin Wang College of Information Science and Engineering Northeastern UniversityShenyangPeople’s Republic of China

False data injection attacks(FDIAs)can manipulate measurement data from Supervisory Control and Data Acquisition(SCADA)system and threat state estimation in smart *** FDIAs(BFDIAs)enhance traditional FDIAs,which eliminate the limitation of grasping measurement Jacobian matrix H in advance,but when there are outliers in measurement data,attack performance is *** this paper,improved BFDIAs are *** off-line phase,lowdimensional measurement matrix without outliers calculated by Linear Local Tangent Space Alignment algorithm(LLTSA)is sent into Continuous Deep Belief Network(CDBN)as training data to learn their probability *** on-line phase,real-time low-dimensional measurement matrix with outliers are sent into the trained model as inputs,and outputs are reconstructed by the probability distribution in off-line phase,which eliminates the influence of outliers *** are implemented on PJM 5-bus and IEEE 14-bus systems to verify the performance of proposed strategy compared with PCA-based BFDIAs.

关键词： Smart grids blind false data injection attacks measurement outliers continuous deep belief network linear local tangent space alignment algorithm

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Motion planning for redundant prismatic-jointed manipulators in the free-floating mode

引用

Acta Mechanica Sinica 2012年第5期28卷 1449-1456页

作者： Xiao-Dong Liu He-Xi Baoyin xing-Rui ma School of Aerospace Tsinghua University

This paper investigates the motion planning of redundant free-floating manipulators with seven prismatic joints. On the earth, prismatic-jointed manipulators could only position their end-effectors in a desired way. However, in space, the end-effectors of free-floating manipulators can achieve both the desired orientation and desired position due to the dynamical coupling between manipulator and satellite movement, which is formally expressed by linear and angular momentum conservation laws. In this study, a tractable algorithm particle swarm optimization combined with differential evolution （PSODE） is provided to deal with the motion planning of redundant free-floating prismatic-jointed manipulators, which could avoid the pseudo inverse of the Jacobian matrix. The polynomial functions, as argument in sine functions are used to specify the joint paths. The co- efficients of the polynomials are optimized to achieve the desired end-effector orientation and position, and simulta- neously minimize the unit-mass-kinetic energy using the redundancy. Relevant simulations prove that this method pro- vides satisfactory smooth paths for redundant free-floating prismatic-jointed manipulators. This study could help to recognize the advantages of redundant prismatic-jointed space manipulators.

关键词： Motion planning - Prismatic joints - Space manipulators Redundant manipulators Free-floating robots ~Nonholonomic planning

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Global patterns in above-ground net primary production and precipitation-use efficiency in grasslands

引用

Journal of Mountain Science 2018年第8期15卷 1682-1692页

作者： QIN Xiao-jing HONG Jiang-tao ma xing-xing WANG Xiao-dan Key Laboratory of Mountain Surface Processes and Ecological Regulation Institute of Mountain Hazards and EnvironmentChinese Academy of ScienceChengdu 610041China University of Chinese Academy of Sciences Beijing 100049China College of Urban and Environment Sciences Shanxi Normal UniversityLinfen 041000China

The above-ground net primary production(ANPP) and the precipitation-use efficiency(PUE) regulate the carbon and water cycles in grassland ecosystems, but the relationships among the ANPP, PUE and precipitation are still controversial. We selected 717 grassland sites with ANPP and mean annual precipitation(maP) data from 40 publications to characterize the relationships ANPP–maP and PUE–maP across different grassland types. The maP and ANPP showed large variations across all grassland types, ranging from 69 to 2335 mm and 4.3 to 1706 g m^(-2), respectively. The global maximum PUE ranged from 0.19 to 1.49 g m^(-2) mm^(-1) with a unimodal pattern. Analysis using the sigmoid function explained the ANPP–maP relationship best at the global scale. The gradient of the ANPP–maP graph was small for arid and semi-arid sites(maP maP across dry grassland ecosystems. It provides new perspectives on the prediction and modeling of variations in the ANPP for different grassland types along precipitation gradients.

关键词： Litter decomposition Alpine communities Tea bag index Carbon cycle Above-ground net primary production Precipitation-use efficiency Sigmoid function Precipitation gradients

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Parameters inversion of high central core rockfill dams based on a novel genetic algorithm

引用

Science China(Technological Sciences) 2016年第5期59卷 783-794页

作者： ZHOU Wei LI Shao Lin ma Gang CHANG Xiao Lin ma xing ZHANG Chao State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan University Changjiang Institute of Survey Planning Design and Research

Parameters identification of rockfill materials is a crucial issue for high rockfill dams. Because of the scale effect, random sampling and sample disturbance, it is difficult to obtain the actual mechanical properties of rockfill from laboratory tests. Parameters inversion based on in situ monitoring data has been proven to be an efficient method for identifying the exact parameters of the rockfill. In this paper, we propose a modified genetic algorithm to solve the high-dimension multimodal and nonlinear optimal parameters inversion problem. A novel crossover operator based on the sum of differences in gene fragments(So DX) is proposed, inspired by the cloning of superior genes in genetic engineering. The crossover points are selected according to the difference in the gene fragments, defining the adaptive length. The crossover operator increases the speed and accuracy of algorithm convergence by reducing the inbreeding and enhancing the global search capability of the genetic algorithm. This algorithm is compared with two existing crossover operators. The modified genetic algorithm is then used in combination with radial basis function neural networks(RBFNN) to perform the parameters back analysis of a high central earth core rockfill dam. The settlements simulated using the identified parameters show good agreement with the monitoring data, illustrating that the back analysis is reasonable and accurate. The proposed genetic algorithm has considerable superiority for nonlinear multimodal parameter identification problems.

关键词： rockfill dam parameters back analysis genetic algorithm crossover operator sum of differences in gene fragments

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CALCULATING METHOD OF SERIES FOR TRUE ANOmaLY OF A SPACECRAFT ELLIPTIC ORBIT

引用

Applied mathematics and Mechanics(English Edition) 2005年第11期26卷 1435-1441页

作者：顾晓勤谭朝阳 ma xing-rui Zhongshan College University of Electronic Science and Technology of China Zhongshan 528403 Guangdong Province P. R. China 不详

The transcendental equation of a true anomaly was written in a power series instead of a differential form. When the sufficient condition of the iterative convergence is satisfied, the relationship between the true anomaly and the time was gotten by the iterative method. And for the others, the transcendental equation of an eccentric anomaly was solved by the iterative method. After the eccentric anomaly had been calculated, the relationship between the true anomaly and the time was gotten with the numerical integral method. The approximate equation, which included the first five terms in general expansion, was written for the spacecraft quasi-circular orbit. And the true anomaly as the function of the time was also gotten by the iterative method. The numerical simulation results show that these methods are efficient.

关键词： spacecraft orbit true anomaly eccentric anomaly iterative method

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：