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Long-Term Changes in Summer Extreme Wet Bulb Globe Temperature over China

Journal of Meteorological Research 2021年第6期35卷 975-986页

作者： Dongqian WANG ying sun Laboratory for Climate Studies National Climate CenterChina Meteorological AdministrationBeijing 100081 Collaborative Innovation Center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044

The wet bulb globe temperature(WBGT)has important implication for human *** studies widely use the monthly data but rarely investigate the extreme WBGT because of data *** this study,we use 6-h station data to analyze the changes in the WBGT and three categories(intensity,absolute threshold,and frequency indices)of extreme WBGT indices in summers of *** is found that the spatial distributions of long-term trends in summer mean WBGT are consistent with those in the mean *** trend value of WBGT is smaller than the mean temperature,because of the decrease of relative *** the extreme indices,the intensity and frequency of WBGT and fixed threshold indices have *** increase of intensity indices and warm WBGT days and nights,and decrease of cold WBGT days and nights have been observed in most China,especially over northwestern *** number of days with daily maximum WBGT exceeding 31.4℃(WXge31)and minimum WBGT exceeding 27.9℃(WNge27)over southeastern China have increased since *** spread of probability distributions of WXge31,WNge27,and warm WBGT days and nights is becoming wider,reflecting increased variability of extreme *** addition,urbanization effects on the WBGT are *** impacts of urbanization on most of extreme WBGT indices are not detected,except for absolute thresholds *** may be due to the decrease of relative humidity in urban stations,which are almost two times larger than that in rural ***,we also note that the homogenization issue of humidity data may affect the conclusions.

关键词： wet bulb globe temperature(WBGT) extreme index long-term change urbanization effect

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Boron neutron capture therapy: moving towards targeted therapy for locally recurrent head and neck squamous cell carcinoma

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Military Medical Research 2020年第2期7卷 239-241页

作者： ying sun Department of Radiation Oncology Sun Yat-sen University Cancer CenterState Key Laboratory of Oncology in South ChinaCollaborative Innovation Center for Cancer MedicineGuangdong Key Laboratory of Nasopharyngeal Carcinoma Diagnosis and TherapyGuangzhou 510060China

Locally recurrent head and neck squamous cell carcinoma(HNSCC)is often unresectable,and a repeat course of radiotherapy is associated with incremental *** neutron capture therapy(BNCT)is a novel targeted radiotherapy modality that can achieve a high dose gradient between cancerous and adjacent normal ***,the relationships among the dose resulting from BNCT,tumor response to BNCT,and survival are not completely ***,a study published in Radiotherapy and Oncology investigated the efficacy of BNCT in the treatment of patients with locally recurrent HNSCC and the factors associated with favorable treatment response and *** this article,the findings,strengths and limitations of this study are discussed in depth,and the significance of the study and motivations for future research are highlighted.

关键词： Locally recurrent head and neck squamous cell carcinoma Boron neutron capture therapy Treatment efficacy

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血清β_2微球蛋白、凝血酶原活动度与慢性乙肝分度的关系研究

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胃肠病学和肝病学杂志 2003年第1期12卷 69-70页

作者：辛永宁孙樱张健张梅吕维红初蕾蕾李宁青岛市市立医院青岛266011

目的　研究血清 β2 微球蛋白与慢性乙肝分度的关系。方法　 67例慢性乙肝按 2 0 0 0标准[1] 分为轻、中、重度 3组 ,用放免法测定患者血 β2 微球蛋白水平 ,同时测定凝血酶原活动度 (PTA)。结果　血清 β2 微球蛋白值随肝功能损伤程度... 详细信息

目的　研究血清 β2 微球蛋白与慢性乙肝分度的关系。方法　 67例慢性乙肝按 2 0 0 0标准[1] 分为轻、中、重度 3组 ,用放免法测定患者血 β2 微球蛋白水平 ,同时测定凝血酶原活动度 (PTA)。结果　血清 β2 微球蛋白值随肝功能损伤程度的加重而升高 ,且与PTA呈负相关。结论　血清 β2 微球蛋白可作为肝脏损伤诊断的辅助指标。

关键词：血清 β2微球蛋白凝血酶原活动度慢性乙型肝炎

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Non-coding RNAs in acute ischemic stroke:from brain to periphery

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Neural Regeneration Research 2025年第1期20卷 116-129页

作者： Shuo Li Zhaohan Xu Shiyao Zhang Huiling sun Xiaodan Qin Lin Zhu Teng Jiang Junshan Zhou Fuling Yan Qiwen Deng Department of Neurology Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina Department of Neurology Zhongda HospitalSchool of MedicineSoutheast UniversityNanjingJiangsu ProvinceChina General Clinical Research Center Nanjing First HospitalNanjing Medical UniversityNanjingJiangsu ProvinceChina

Acute ischemic stroke is a clinical emergency and a condition with high morbidity,mortality,and *** predictive,diagnostic,and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain *** innovations in high-throughput gene sequencing analysis,many aberrantly expressed non-coding RNAs(ncRNAs)in the brain and peripheral blood after acute ischemic stroke have been found in clinical samples and experimental *** expressed ncRNAs in the post-stroke brain were demonstrated to play vital roles in pathological processes,leading to neuroprotection or deterioration,thus ncRNAs can serve as therapeutic targets in acute ischemic ***,distinctly expressed ncRNAs in the peripheral blood can be used as biomarkers for acute ischemic stroke prediction,diagnosis,and *** particular,ncRNAs in peripheral immune cells were recently shown to be involved in the peripheral and brain immune response after acute ischemic *** this review,we consolidate the latest progress of research into the roles of ncRNAs(microRNAs,long ncRNAs,and circular RNAs)in the pathological processes of acute ischemic stroke–induced brain damage,as well as the potential of these ncRNAs to act as biomarkers for acute ischemic stroke prediction,diagnosis,and *** from this review will provide novel ideas for the clinical application of ncRNAs in acute ischemic stroke.

关键词： acute ischemic stroke apoptosis blood–brain barrier damage circular RNAs excitatory toxicity long non-coding RNAs microRNAs neuroinflammation non-coding RNAs oxidative stress

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Lithiophilic montmorillonite as a robust substrate toward high-stable lithium metal anodes

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Rare Metals 2023年第7期42卷 2157-2165页

作者： Meng Wang ying Li Sheng-Yang Li xin-xin Jia Bo Nie Hong-Tao sun Ya-Ya Wang Jian Zhu State Key Laboratory for Chemo/Biosensing and Chemometrics College of Chemistry and Chemical EngineeringHunan Key Laboratory of Two-Dimensional MaterialsEngineering Research Center of Advanced CatalysisMinistry of EducationHunan UniversityChangsha410082China The Harold&Inge Marcus Department of Industrial and Manufacturing Engineering The Pennsylvania State UniversityState CollegePA16802USA Materials Research Institute(MRI) The Pennsylvania State UniversityState CollegePA16802USA

Lithium metal is considered a desirable anode for the nextgeneration high-energy-density rechargeable energy storage ***,poor lifespan and safety issues caused by unexpected dendrites growth have prevented the commerc... 详细信息

关键词： lithium anode high

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Crystallinity and stability of covalent organic frameworks

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Science China Chemistry 2020年第10期63卷 1367-1390页

作者： xin Huang Chao sun Xiao Feng Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials Key Laboratory of Cluster ScienceMinistry of EducationSchool of Chemistry and Chemical EngineeringBeijing Institute of TechnologyBeijing 100081China

Covalent organic frameworks(COFs)are a class of organic porous polymers with high crystallinity,and their structures can be precisely tailored via topology *** to the characteristics of permanent pores,periodic structures and rich building blocks,COFs have triggered tremendous attention in the past fifteen years and are extensively investigated in various *** and stability are two crucial features for practical *** general,these two features are contradictory for COFs formed via dynamic covalent chemistry(DCC).High thermodynamic reversibility is usually required to attain exceptional crystallinity of COFs,often resulting in limited *** first two reported COFs are based on the boroxine and boronate ester linkages,which are unstable in water and even in humid ***,many researchers doubt the stability of COFs for real ***,in these years,various novel linkages have been developed for the construction of COFs,and numerous newly synthesized COFs are robust towards strong acid/base and even some of them can resist the attack of strong oxidizing and reducing *** this review,we focus on the linkage chemistry of the COFs in terms of crystallinity and stability,further extending it to the investigation in the mechanisms of the crystal growth and the overall regulation of the contradiction between stability and *** strategies for improving the crystallinity,including selecting building units,introducing non-covalent interactions and slowing nucleation and growth rate,are described in the third section,while the methodologies for increasing the stability from the viewpoints of chemical modification and non-covalent interactions are summarized in the fourth ***,the challenges and perspectives are presented.

关键词： covalent organic frameworks crystallinity stability dynamic covalent chemistry linkage chemistry

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Event-triggered receding horizon control via actor-critic design

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Science China(Information Sciences) 2020年第5期63卷 131-145页

作者： Lu DONG xin YUAN Changyin sun School of Automation Southeast University College of Electronics and Information Engineering Tongji University Key Laboratory of Measurement and Control of Complex Systems of Engineering Ministry of EducationSoutheast University

In this paper, we propose a novel event-triggered near-optimal control for nonlinear continuoustime systems. The receding horizon principle is utilized to improve the system robustness and obtain better dynamic control performance. In the proposed structure, we first decompose the infinite horizon optimal control into a series of finite horizon optimal problems. Then a learning strategy is adopted, in which an actor network is employed to approximate the cost function and an critic network is used to learn the optimal control law in each finite horizon. Furthermore, in order to reduce the computational cost and transmission cost, an event-triggered strategy is applied. We design an adaptive trigger condition, so that the signal transmissions and controller updates are conducted in an aperiodic way. Detailed stability analysis shows that the nonlinear system with the developed event-triggered optimal control policy is asymptotically *** results on a single-link robot arm with different noise types have demonstrated the effectiveness of the proposed method.

关键词： event-triggered control receding horizon control actor-critic design optimal control nonlinear systems neural networks

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Dry Port-Seaport Logistics Network Construction under the Belt and Road Initiative: A Case of Shandong Province in China

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Journal of Systems Science and Systems Engineering 2021年第2期30卷 178-197页

作者： Jingci Xie Yiran sun xin Huo School of Management Shandong UniversityJi'nan 250100China CRRC Qingdao Sifang Co.Ltd Qingdao 266111China

In recent years,China's dry ports have entered into a period of rapid development,especially driven by the Belt and Road initiative(BRI).This initiative not only provides valuable opportunities,but also intensifies fierce competition between *** order to earn more profits and maintain an advantageous position,dry ports generally tend to rely on seaports to increase competitiveness and attract more goods,and seaports are also willing to cooperate with dry ports to expand their *** a large coastal province in China,Shandong Province has good maritime *** of the fierce competition among seaports inside and outside Shandong Province,port operators should make good use of the opportunity offered by BRI to make connections with the inland cities through the dry port-seaport logistics network and enhance the *** order to take an active part in the process of the BRI,forming a dry port-seaport logistics network is a win-win strategy for Shandong *** research first analyzes the impact of the Belt and Road initiative on ports of Shandong and its development,then uses complex network theory and TOPSIS method to select dry port candidate cities from BRI's important transportation *** considering economic benefits,carbon emissions and construction costs,a multi-objective optimization model is established with a construction cost preference *** the NSGA-II algorithm is used to solve the realistic *** study finds that when the construction cost increases,the transportation cost and carbon emission cost will decrease,which indicates that the dry port-seaport logistics network established under the BRI can reduce the cost of logistics transportation and environmental pollution.

关键词： Dry port Belt and Road Initiative logistics network mathematical programming

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A fast, accurate and dense feature matching algorithm for aerial images

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Journal of Systems Engineering and Electronics 2020年第6期31卷 1128-1139页

作者： LI ying GONG Guanghong sun Lin School of Automation Science and Electrical Engineering Beihang UniversityBeijing 100191China

Three-dimensional(3D)reconstruction based on aerial images has broad prospects,and feature matching is an important step of ***,for high-resolution aerial images,there are usually problems such as long time,mismatching and sparse feature pairs using traditional ***,an algorithm is proposed to realize fast,accurate and dense feature *** algorithm consists of four ***,we achieve a balance between the feature matching time and the number of matching pairs by appropriately reducing the image ***,to realize further screening of the mismatches,a feature screening algorithm based on similarity judgment or local optimization is ***,to make the algorithm more widely applicable,we combine the results of different algorithms to get dense ***,all matching feature pairs in the low-resolution images are restored to the original *** between the original algorithms and our algorithm show that the proposed algorithm can effectively reduce the matching time,screen out the mismatches,and improve the number of matches.

关键词： feature matching feature screening feature fusion aerial image three-dimensional(3D)reconstruction

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Supplementation of Fermented Barley Extracts with Lactobacillus Plantarum dy-1 Inhibits Obesity via a UCP1-dependent Mechanism

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Biomedical and Environmental Sciences 2019年第8期32卷 578-591页

作者： XIAO Xiang BAI Juan LI Ming Song ZHANG Jia Yan sun xin Juan DONG ying School of Food and Biological Engineering Jiangsu University

Objective We aimed to explore how fermented barley extracts with Lactobacillus plantarum dy-1(LFBE) affected the browning in adipocytes and obese *** In vitro, 3T3-L1 cells were induced by LFBE, raw barley extraction(RBE) and polyphenol compounds(PC) from LFBE to evaluate the adipocyte *** vivo, obese SD rats induced by high fat diet(HFD) were randomly divided into three groups treated with oral gavage:(a) normal control diet with distilled water,(b) HFD with distilled water,(c) HFD with 800 mg LFBE/kg body weight(bw).Results In vitro, LFBE and the PC in the extraction significantly inhibited adipogenesis and potentiated browning of 3T3-L1 preadipocytes, rather than *** vivo, we observed remarkable decreases in the body weight, serum lipid levels, white adipose tissue(WAT) weights and cell sizes of brown adipose tissues(BAT) in the LFBE group after 10 *** group could gain more mass of interscapular BAT(IBAT) and promote the dehydrogenase activity in the *** LFBE may potentiate process of the IBAT thermogenesis and epididymis adipose tissue(EAT) browning via activating the uncoupling protein 1(UCP1)-dependent mechanism to suppress the *** These results demonstrated that LFBE decreased obesity partly by increasing the BAT mass and the energy expenditure by activating BAT thermogenesis and WAT browning in a UCP1-dependent mechanism.

关键词： Fermented barley Polyphenol compounds UCP1 Thermogenesis Browning

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