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Asian Journal of Andrology 2022年第1期24卷 62-66页

作者： Yong Zhu Feng Zhang Hua cheng xiao-Xi Sun Feng Jiang Obstetrics and Gynecology Hospital Fudan UniversityShanghai 200011China Shanghai Ji Ai Genetics and IVF Institute Obstetrics and Gynecology HospitalFudan UniversityShanghai 200011China

For infertility treatment,the selection of in vitro fertilization(IVF)or intracytoplasmic sperm injection(ICSI)is decided by multiplying indicators(including fallopian tube factors,semen count,and semen motility),except for sperm *** this study,we conducted a retrospective analysis,from implantation to birth,over a period of 5 years.A total of 1873 couples with primary or secondary fallopian tube factors and an increased defective sperm morphology rate(DSMR)were divided into different groups to receive IVF or ICSI *** comparing the outcomes,we found that the F1 group(DSMR98%,IVF group 3;P98%,ICSI group 3)had higher cleavage rate(P<0.001),biochemical pregnancy rate(P<0.05),clinical pregnancy rate(P<0.05)and live birth rate(P<0.05)than the F3 ***,the ICSI subgroup had a lower two pronuclei fertilization rate than the IVF subgroup(P<0.05).Our data suggest that the sperm morphology should also be considered when selecting IVF or ICSI combined with other semen parameters before the first assisted reproductive technologies(ART)cycle,especially for males with severe sperm defects.

关键词： clinical outcome in vitro fertilization intracytoplasmic sperm injection sperm morphology

Regulation of Axon Initial Segment Diameter by COUP-TFI Fine-tunes Action Potential Generation

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Neuroscience Bulletin 2022年第5期38卷 505-518页

作者： Xuanyuan Wu Haixiang Li Jiechang Huang Mengqi Xu cheng xiao Shuijin He School of Life Science and Technology ShanghaiTech UniversityShanghai 201210China Institute of Neuroscience Center for Excellence in Brain Science and Intelligence TechnologyChinese Academy of SciencesShanghai 200031China University of Chinese Academy of Sciences Beijing 100049China School of Anesthesiology Xuzhou Medical UniversityXuzhou 221004China

The axon initial segment(AIS)is a specialized structure that controls neuronal excitability via action potential(AP)***,AIS plasticity with regard to changes in length and location in response to neural activity has been extensively investigated,but how AIS diameter is regulated remains *** we report that COUP-TFI(chicken ovalbumin upstream promotor-transcription factor 1)is an essential regulator of AIS diameter in both developing and adult mouse *** embryonic or adult ablation of COUP-TFI results in reduced AIS diameter and impaired AP *** COUP-TFI ablations in sparse single neurons and in populations of neurons have similar impacts on AIS diameter and AP generation,they strengthen and weaken,respectively,the receiving spontaneous network in mutant *** contrast,overexpression of COUP-TFI in sparse single neurons increases the AIS diameter and facilitates AP generation,but decreases the receiving spontaneous *** findings demonstrate that COUP-TFI is indispensable for both the expansion and maintenance of AIS diameter and that AIS diameter fine-tunes action potential generation and synaptic inputs in mammalian cortical neurons.

关键词： COUP-TFI Axon initial segment Action potential Diameter

Effect of cellular recrystallization on tensile properties of a nickel-based single crystal superalloy containing Re and Ru

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Journal of Iron and Steel Research International 2017年第10期24卷 1059-1064页

作者： Zhen-xue Shi Shi-zhong Liu xiao-dai Yue Li-jie Hu Wan-peng Yang xiao-guang Wang Jia-rong Li Science and Technology on Advanced High Temperature Structural Materials Laboratory Beijing Institute of Aeronautical MaterialsBeijing 100095China

A nickel-based single crystal superalloy containing Re and Ru was cast in a directional solidification *** single crystal specimens after standard heat treatment were grit blasted with different pressures and then heat treated at 1100°C for 4 hunder vacuum *** evolution of recrystallized microstructure and its effect on the tensile properties at 850 and 980°C were *** heat treatment,the cellular microstructure was observed,and the thickness of the cellular recrystallization zone increases with the increase in grit blasting *** appearance of the cellular structure undermines the tensile *** the tensile strength and elongation decrease with increasing the thickness of the cellular *** recrystallized grain boundaries can act as the channels for the crack initiation and propagation during tensile *** low bearing capacity of recrystallized layers and the local stress concentration resulting from the notch effect of cracking were the main reasons for the decrease of tensile properties.

关键词： Single crystal superalloy Cellular recrystallization Tensile property Microstructure Fracture morphology

Observation and simulation of wind waves near a typical reef lagoon in South China Sea

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Journal of Hydrodynamics 2021年第1期33卷 24-32页

作者： Ze Sun Dao-lin Xu xiao-long Liu Hai-cheng Zhang Zhi-wen Cai China Ship Scientific Research Center Wuxi 214082China Centre for Marine Technology Hunan UniversityChangsha 410082China Southern Marine Science and Engineering Guangdong Laboratory Zhanjiang 524025China

Due to the inference of the uneven shallow water seabed and the surrounding islands,the wind-generated waves around or in a reef lagoon are rather complicated,and critical to the safety of floating structures deployed near islands or inside a *** paper aims to find a feasible analysis tool for the wave simulations near islands and *** proposed three methods of grid techniques of WAVEWATCH III(WW3)are assessed by using on-site measured data which was collected and accumulated for about 5 years since August 2014 by a wave observation system deployed inside and outside a reef lagoon in South China *** the assessments,the wave statistics including the correlation coefficients,root mean square errors,and their variances are used to quantify the precisions of the simulation results of the significant wave heights,mean wave periods,and peak wave directions at two *** the three methods,the Multi-scale Zone and Multi-scale grid Technique(MZMGT)established on unstructured triangular grids exhibits better results in terms of the accuracy and CPU *** addition,the bimodal feature of wave spectra was observed at both sites of the reef lagoon in different typhoon *** wave characteristics inside the reef lagoon and open sea are also analyzed.

关键词： Wave simulation reef lagoon WAVEWATCH III(WW3) grid methods typhoon waves on-site measurements

Lycopodine-Type Alkaloids from Lycopodium japonicum

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Natural Products and Bioprospecting 2014年第4期4卷 213-219页

作者： Juan He Xing-De Wu Fei Liu Yu-cheng Liu Li-Yan peng Yu Zhao xiao cheng Huai-Rong Luo Qin-Shi Zhao State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of BotanyChinese Academy of SciencesKunming 650201China

Three new lycopodine-type alkaloids,4a-hydroxyanhydrolycodoline(1),4a,6a-dihydroxyanhydrolycodoline(2),and 6-epi-8b-acetoxylycoclavine(3),and an artifact,lycoposerramine G nitrate(4),along with seventeen related known compounds,were isolated from the club moss Lycopodium japonicum *** Murray(Lycopodiaceae).Their structures were elucidated by extensive spectroscopic methods as well as X-ray *** 1–4 were evaluated for their acetylcholine esterase inhibitory activity.

关键词： Lycopodium japonicum Lycopodine-type alkaloids 4a-Hydroxyanhydrolycodoline 4a,6a-Dihydroxyanhydrolycodoline 6-epi-8b-Acetoxylycoclavine Lycoposerramine G nitrate

The Characterization of Graphs with No 2-connected Spanning Subgraph of V_(8)as a Minor

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Acta Mathematicae Applicatae Sinica 2022年第4期38卷 902-915页

作者： xiao-min ZHOU Xia-xia GUAN cheng-fu QIN Wei-hua YANG Department of Mathematics Taiyuan University of TechnologyTaiyuan 030000China School of Mathematical Sciences Xiamen UniversityXiamen 361005China School of Mathematics Science Guangxi Teachers Education UniversityNanning 530001China

It is difficult to characterize graphs which contain no a 2-connected graph as a minor in graph *** V_(8)be a graph constructed from an 8-cycle by connecting the antipodal *** are thirteen 2-connected spanning subgraphs of V_(8).In particular,one of them is obtained from the Petersen graph by deleting two vertices and it is also a hard problem to characterize Petersen-minor-free *** this paper,we characterize internally 4-connected graphs which contain a 2-connected spanning subgraph of V_(8)as a forbidden minor.

关键词： V_(8) internally 4-connected graph minor-free 2-connected subgraph

Corrosion behavior of Cu/Al casting-rolled clad plates in different alkaline solution

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China Foundry 2021年第5期18卷 513-520页

作者： Yi-fan Zhang xiao-guang Yuan xiao-jiao Zuo Hong-jun Huang Yu-lin cheng School of Materials Science and Engineering Shenyang University of technologyShenyang 110870China

The effect of pH value and different kinds of anions on the corrosion behavior of Cu/Al casting-rolled clad plates in the alkaline solution was evaluated by means of scanning electron microscopy(SEM),energy dispersive spectroscopy(EDS),X-ray diffraction(XRD),weight loss analysis,3D confocal laser scanning microscopy(CLSM)and electrochemical *** show the corrosion mainly occurs on the aluminum *** corrosion resistance of the Cu/Al decreases as the pH value *** pH≥12,the dissolution of the film layer is faster than the passivation *** addition of Cl^(-)ions reduces the corrosion resistance of the Cu/Al clad plates,which leads to pitting *** higher the concentration of Cl^(-)ions,the more prone the pitting to *** addition of SO_(4)^(2-)ions causes the denudation of the *** corrosion resistance of the Cu/Al is better in the alkaline solution containing NO_(3)^(-)ions than that in the solution containing Cl^(-)ions or SO_(4)^(2-)*** adding SO_(4)^(2-),NO^(3)^(-)and Cl^(-)to the pure alkaline solution,the corrosion resistance of the Cu/Al clad plates decreases.

关键词： Cu/Al clad plates alkaline solution pH anions electrochemistry casting-rolled

Robust Co_(3)O_(4)nanocatalysts supported on biomass-derived porous N-doped carbon toward low-pressure hydrogenation of furfural

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Frontiers of Materials Science 2023年第2期17卷 155-168页

作者： Lin Zhang Lanlan cheng Yechen Hu Qingguang xiao Xiufang Chen Wangyang Lu National Engineering Lab for Textile Fiber Materials&Processing Technology(Zhejiang) Zhejiang Sci-Tech UniversityHangzhou 310018China

The catalytic conversion of biomass platform chemicals using abundant non-noble metal nanocatalysts is a challenging ***,high-density cobalt oxide nanoparticles loaded on biomass-derived porous N-doped carbon(NC)was fabricated by a tandem hydrothermal pyrolysis and mild nitrate decomposition process,which is a green and cheap preparation *** Co_(3)O_(4) nanoparticles with the average size of 12 nm were uniformly distributed on the porous *** nanocomposites also possessed large surface area,high N content,good dispersibility in isopropanol,and furfural *** to these characteristics,the novel cobalt nanocatalyst exhibited high catalytic activity for producing furfuryl alcohol,yielding 98.7%of the conversion and 97.1%of the selectivity at 160℃ for 6 h under 1 bar *** control experiments implied that both direct hydrogenation and transfer hydrogenation pathways co-existed in the hydrogenation *** excellent catalytic activity of Co_(3)O_(4)@NC was attributed to the cooperative effects of porous NC and Co_(3)O_(4) *** approach provides a new idea to design effective high-density nonnoble metal oxide nanocatalysts for hydrogenation reactions,which can make full use of sustainable natural biomass.

关键词： biomass N-doped carbon cobalt oxide nanoparticle hydrogenation reaction low pressure

软组织平衡技术治疗老年重度膝骨关节炎30例临床观察

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风湿病与关节炎 2024年第6期13卷 16-20页

作者：程亭秀齐逸凡马晓婷曹景文肖丙龙程广耀东宁市第一人民医院黑龙江东宁157299 空军军医大学基础医学院三大队陕西西安710032 吉林体育学院研究生院吉林长春130022

目的:观察软组织平衡技术治疗老年重度膝骨关节炎的临床疗效。方法:将60例老年重度膝骨关节炎患者随机分为治疗组和对照组,每组30例。对照组采用传统推拿方法治疗,治疗组采用软组织平衡技术治疗,2组疗程均为4周。观察2组临床疗效,以及... 详细信息

目的:观察软组织平衡技术治疗老年重度膝骨关节炎的临床疗效。方法:将60例老年重度膝骨关节炎患者随机分为治疗组和对照组,每组30例。对照组采用传统推拿方法治疗,治疗组采用软组织平衡技术治疗,2组疗程均为4周。观察2组临床疗效,以及治疗前后美国特种外科医院(HSS)评分和视觉模拟评分法(VAS)评分。结果:治疗组治愈14例,显效10例,有效5例,无效1例,总有效率为96.67%;对照组治愈7例,显效5例,有效10例,无效8例,总有效率为73.33%。2组比较,差异有统计学意义(P < 0.01)。治疗后,2组HSS评分和VAS评分较治疗前均有改善(P < 0.01);且治疗组改善程度优于对照组(P < 0.01)。结论:软组织平衡技术保守治疗老年重度膝骨关节炎简单、实用、效果显著,适合临床推广。

关键词：重度膝骨关节炎老年软组织平衡技术临床疗效

国产脊髓电刺激系统在小尾寒羊植入的长期安全性和组织相容性研究

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中国疼痛医学杂志 2024年第8期30卷 568-577页

作者：章沿锋蔡世宏柳成江李云泽彭志友冯智英浙江大学医学院附属第一医院疼痛科杭州310003 台州市中心医院(台州学院附属医院)疼痛科台州318000

目的:验证国产脊髓电刺激(spinal cord stimulation,SCS)系统的可操作性、长期安全性和组织相容性。方法:成年雄性小尾寒羊9只,其中3只为短期植入组(S组)即SCS电极植入2周;另6只为长期植入组(L组)即SCS电极和脉冲发生器植入长达26周。... 详细信息

目的:验证国产脊髓电刺激(spinal cord stimulation,SCS)系统的可操作性、长期安全性和组织相容性。方法:成年雄性小尾寒羊9只,其中3只为短期植入组(S组)即SCS电极植入2周;另6只为长期植入组(L组)即SCS电极和脉冲发生器植入长达26周。观察术前(T_(0))、术后1周(T_(1))、2周(T_(2))、4周(T_(3))、8周(T_(4))、12周(T_(5))、20周(T_(6))、26周(T_(7))实验羊的行为学改变、实验室检查、设备电阻抗值、高频低频刺激情况、电极移位等,S组和L组分别于术后2周和26周取SCS周围组织行苏木精-伊红染色行病理性检查。结果:S组和L组植入SCS后运动正常。与术前相比,S组与L组的血常规、肝肾功能和凝血功能无明显变化(P>0.05)。但与术前相比,L组实验羊血糖水平在术后2、4、8、12周均明显降低(P<0.05)。术中及术后阻抗值正常,电极未见移位。刺激节段脊髓形态结构正常,未见明显坏死、水肿、缺血、炎症等病理改变。结论:国产植入式SCS系统可操作性良好,长期植入后具有良好的生物相容性和安全性,符合临床应用需求。

关键词：脊髓电刺激生物安全性组织相容性小尾寒羊