Lycopodine-Type Alkaloids from Lycopodium japonicum

作     者：Juan He Xing-De Wu Fei Liu Yu-Cheng Liu Li-Yan Peng Yu Zhao Xiao Cheng Huai-Rong Luo Qin-Shi Zhao 

作者机构：State Key Laboratory of Phytochemistry and Plant Resources in West ChinaKunming Institute of BotanyChinese Academy of SciencesKunming 650201China 

出 版 物：《Natural Products and Bioprospecting》 (应用天然产物（英文）)

年 卷 期：2014年第4卷第4期

页      面：213-219页

学科分类：081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 070303[理学-有机化学] 0703[理学-化学] 

基　　金：the National Natural Science Foundation of China(Nos.90813004 and U0932602) the National Basic Research Program of China(973 Program No.2011CB915503) 

主　　题：Lycopodium japonicum Lycopodine-type alkaloids 4a-Hydroxyanhydrolycodoline 4a,6a-Dihydroxyanhydrolycodoline 6-epi-8b-Acetoxylycoclavine Lycoposerramine G nitrate 

摘      要：Three new lycopodine-type alkaloids,4a-hydroxyanhydrolycodoline(1),4a,6a-dihydroxyanhydrolycodoline(2),and 6-epi-8b-acetoxylycoclavine(3),and an artifact,lycoposerramine G nitrate(4),along with seventeen related known compounds,were isolated from the club moss Lycopodium japonicum *** Murray(Lycopodiaceae).Their structures were elucidated by extensive spectroscopic methods as well as X-ray *** 1–4 were evaluated for their acetylcholine esterase inhibitory activity.