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Chinese Chemical Letters 2021年第4期32卷 1377-1380页

作者： Tangxin xiao Jie Wang Yong Shen cheng Bao Zheng-Yi Li xiao-Qiang Sun Leyong Wang School of Petrochemical Engineering Changzhou UniversityChangzhou 213164China School of Chemistry and Chemical Engineering Nanjing UniversityNanjing 210023China

Benzo-21-crown-7(B21 C7)is one of the most important crown ethers,which not only shows excellent physicochemical properties but also exhibits promising binding capability with dialkylammonium *** this paper,we designed and synthesized a fixed-tetraphenylethylene(FTPE)motif bridged ditopic benzo-21-crown-7 molecule(H).The fixed tetraphenylethylene motif endows H with aggregation induced emission(AIE)prope *** the presence of a ditopic dialkylammonium salt guest molecule(G),a fluorescent supramolecular polymer with golden luminescent property could be *** B21 C7-based host-guest supramolecular polymer with golden fluorescence may have potential application in dynamic luminescent materials.

关键词： Benzo-21-crown-7 Host-guest interaction Supramolecular polymer Fluorescent materials AIE

Low-pressure-induced large barocaloric effect in MnAs_(0.94)Sb_(0.06) alloy around room temperature

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Rare Metals 2023年第12期42卷 3977-3984页

作者： peng-Tao cheng Zhao Zhang Xu-Cai Kan cheng-Liang Zhang Zheng-Ming Zhang Bing Li Dun-Hui Wang Division of Microelectronic Materials and Devices Hangzhou Dianzi UniversityHangzhou 310018China National Laboratory of Solid State Microstructures and Department of Physics Nanjing UniversityNanjing 210093China Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang 110016China School of Materials Science and Engineering University of Science and Technology of ChinaHefei 230026China School of Materials Science and Engineering Anhui UniversityHefei 230601China Engineering Technology Research Center of Magnetic Materials School of Physics and Materials ScienceAnhui UniversityHefei 230601China

The barocaloric effect(BCE)is a promising alternative to traditional vapor compressing refrigeration because of its environmentally friendly impact and high energy ***,the driving hydrostatic pressure for most BCE materials is relatively high,which is not conducive to practical *** this paper,we report that the large barocaloric entropy change of MnAs_(0.94)Sb_(0.06)alloy can be induced by low hydrostatic *** phase transition temperature is strongly sensitive to the applied pressure,resulting in a large barocaloric coefficient of 134 K·GPa^(-1)on cooling and 126 K·GPa^(-1)on *** maximum barocaloric entropy change and adiabatic temperaturechange resulted from hydrostatic pressure of 40 MPa reach up to 26.3 J·kg^(-1)·K^(-1)and 14.4 K,respectively,showing an excellent barocaloric *** results demonstrate that the MnAs_(0.94)Sb_(0.06)alloy is a promising alternative for BCE refrigeration.

关键词： alloy hydrostatic

Two Sympathetic Homologous CMEs on 2002 May 22

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Chinese Journal of Astronomy and Astrophysics 2005年第3期5卷 265-272页

作者： Jian-Xiacheng chengFang peng-FeiChen Ming-DeDing DepartmentofAstronomy NanjingUniversityNanjing210093

Sympathetic coronal mass ejections (CMEs) usually occur in different active regions connected by interconnecting magnetic loops, while homologous CMEs occur within the same active region with an almost the same background magnetic field, and so are similar in shapes. Two sympathetic CMEs erupted within 3 hours on 2002 May 22, originating from the same active region, AR 9948. Their multi-wavelength data were collected and analyzed. It is suggested that emerging flux triggered the occurrence of the first CME and the corresponding flare, the reconnection inflow of which in turn triggered the eruption of the second CME. Based on the fact that the two sympathetic CMEs have many similarities, in their shapes, their low-lying dimming areas, etc., we tentatively propose, for the first time, the phenomenon of sympathetic homologous CMEs.

关键词： filament flares CMEs

Prognostic value of glypican-3 in patients with HBV-associated hepatocellular carcinoma after liver transplantation

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Hepatobiliary & Pancreatic Diseases International 2015年第2期14卷 157-163页

作者： xiao Cui Zhao Li peng-Ji Gao Jie Gao Ji-Ye Zhu Department of Hepatobiliary Surgery Peking University People's Hospital

BACKGROUND：Glypican-3（GPC-3）is frequently overexpressed in hepatocellular carcinoma（HCC）.Recent studies have shown that GPC-3 is a highly efficient diagnostic biomarker of HCC and an indicator of poor prognosis in HCC patients who have undergone ***,its prognostic value in patients with HBV-associated HCC after liver transplantation（LT）is not *** present study is to evaluate the prognostic value of GPC-3 in patients with HBV-associated HCC after ***： A cohort of 104 HCC patients with HBV-associ- ated cirrhosis who had undergone LT at our hospital between 2002 and 2011 were enrolled in this study. Samples of HCC were taken from these patients. GPC-3 protein expression was detected in paraffin-embedded specimens using immunohis- tochemistry. All related clinical data were obtained from the China Liver Transplant Registry. The relationship between GPC-3 expression and clinicopathological parameters was analyzed. Univariate and multivariate Cox-regression analyses were used to identify risk factors for poor prognosis. RESULTS： GPC-3 was expressed in samples from 74 （71.2%） of the 104 patients. GPC-3 was expressed only in HCC cells. Positive staining was correlated with tumor size （P=0.004）, encapsulation （P=0.018）, pathological stage （P--0.027）, portal vein invasion （P=0.043）, tumor differentiation （P=0.002） and the Milan criteria （P=0.016）. The 5-year survival rate and dis- ease-free survival rate of patients with GPC-3-positive were lower than those （38.2% vs 75.4%, P〈0.001; 30.8% vs 69.7%, P=0.001） of patients with GPC-3-negative. Multivariate Coxregression analysis revealed that GPC-3 was an independent risk factor for 5-year survival rate （P=0.031） and disease-free survival rate （P=0.047）, together with tumor differentiation, Milan criteria and pre-operative ***： GPC-3 is a potential biomarker for poor prognosis after LT in HCC patients with HBV-associated cirrhosis.

关键词： liver transplantation hepatitis B hepatocellular carcinoma glypican-3

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游戏应用于医学教育研究现状的可视化分析

中国全科医学 2024年第28期27卷 3495-3499,3514页

作者：张鸿飞赵明一冯怡然肖广芬李倩元程洁姚晨姣中南大学湘雅三医院全科医学科湖南省长沙市410013 中南大学湘雅三医院儿科湖南省长沙市410013 中南大学湘雅三医院老年科湖南省长沙市410013

背景游戏是医学教育中一种新兴的教学工具,其被认为是一种潜在的、有吸引力的补充学习形式。近年来对于游戏应用于医学教育的研究逐渐增多,但国内相关研究发展较慢。回顾在医学教育中使用游戏的相关研究文献,全面了解该领域发展现状及热... 详细信息

背景游戏是医学教育中一种新兴的教学工具,其被认为是一种潜在的、有吸引力的补充学习形式。近年来对于游戏应用于医学教育的研究逐渐增多,但国内相关研究发展较慢。回顾在医学教育中使用游戏的相关研究文献,全面了解该领域发展现状及热点,有利于促进我国医学教育研究领域的发展。目的分析游戏应用于医学教育研究的现状,为今后游戏应用于医学教育相关研究提供借鉴与参考。方法于2023年2-4月,借助CiteSpace 6.1R6、Microsoft Excel 2019软件,以“game”and“medical education”为主题,从Web of Science核心合集数据库(WoSCC)检索2013-01-01-2023-02-26共11年间的相关文献,对发文量、作者、国家/机构、关键词、爆发词等进行可视化分析。结果最终纳入652篇英文文献。近11年发文量总体呈上升趋势,美国是发文量(201篇)、中心性(0.48)位居第一的国家,第二和第三分别是加拿大(67篇,中心性0.15)和英国(56篇,中心性0.47)。加拿大多伦多大学以发文量21篇成为发文总量最多的机构。高频关键词包括医学教育、教育、严肃游戏、模拟和表演。关键词突现分析中突现程度最高的关键词是严肃游戏(突现强度3.4)。结论目前,游戏在医学教育中的应用越来越引起学者们的关注,研究热点主要集中在不同游戏在人才培养过程中发挥的作用,但没有高质量的证据为教育者提供证据式建议。我国在该领域仍需进一步探索,需要教育工作者们在教学过程中更多地应用游戏,以更好的对其有效性进行验证,促进医学教育的发展。

关键词：教育,医学游戏 CiteSpace 可视化分析

维普期刊数据库博看期刊

胸椎T_(10)骨肿瘤转移不同位置生物力学特性的三维有限元分析

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中国组织工程研究 2024年第36期28卷 5759-5765页

作者：夏国仁余浩姜世峰彭新伏晓陈琦杨立状王腾飞李海中国科学院合肥肿瘤医院安徽省合肥市230000 中国科学院合肥物质研究院安徽省合肥市230000

背景:随着检查技术的革新,不同分期脊柱转移瘤患者逐年增多,经皮椎体成形是脊柱转移瘤重要的治疗手段,但其治疗不同分期、不同活动方式肿瘤的术后生物力学疗效尚未见报道。目的:基于三维有限元模型模拟胸椎T_(10)骨肿瘤转移不同位置的... 详细信息

背景:随着检查技术的革新,不同分期脊柱转移瘤患者逐年增多,经皮椎体成形是脊柱转移瘤重要的治疗手段,但其治疗不同分期、不同活动方式肿瘤的术后生物力学疗效尚未见报道。目的:基于三维有限元模型模拟胸椎T_(10)骨肿瘤转移不同位置的应力及位移情况。方法:根据1例30岁健康男性胸椎三维CT扫描数据,采用Mimics软件构建胸椎(T_(9)-T_(11))的三维几何模型,包括肋骨、韧带及椎间盘。模拟被胸椎转移瘤侵袭的T_(9)-T_(11)椎体及其后胸椎不同部位的三维模型,包括椎体结构完整的对照组,单侧转移累及椎体区(实验组1),单侧转移累及椎体和椎弓根区(实验组2),单侧转移累及椎体、椎弓根和横突区(实验组3),双侧转移累及椎体、椎弓根和横突区(实验组4)。利用Abaqus软件创建三维有限元模型,对负重、屈曲、伸展、旋转工况下VonMises应力分布及模型的位移情况进行分析。结果与结论:①在对不同实验组加载点在负重、屈曲、伸展、旋转工况下最大总位移的研究中,随着转移瘤侵袭部位及侵袭面的增多,加载点的总位移在增大,整体刚度降低,尤其实验组4加载点的总位移最大;②在屈曲工况下椎体、椎弓根破坏后明显增加最大Von Mises应力值,而在此基础上增加胸肋关节破坏,其最大Von Mises应力值基本不变;③有限元分析并模拟骨肿瘤模型的基础上,将骨水泥区域的单元设置为一个单独的set集合,后将骨水泥区域设置为对应的材料属性以模拟骨水泥填充,结果发现,负重、屈曲、伸展、旋转工况下最大总位移均小于各实验组;④模拟经皮椎体成形治疗后患者在负重、屈曲、伸展、旋转工况下的最大应力值相较于骨肿瘤模型大幅度降低;⑤提示基于胸椎T_(9)-T_(11)的三维有限元模型构建有利于对胸椎骨肿瘤转移生物力学特性的研究,并能够在胸椎骨肿瘤转移模型的基础上准确模拟经皮椎体成形后加载点在不同工况下的总位移及最大VonMises应力情况。

关键词：脊柱转移瘤经皮椎体成形骨水泥有限元模型生物力学分析

低剂量利伐沙班与低分子量肝素钙在急性肺栓塞患者中的应用比较

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中国合理用药探索 2024年第4期21卷 83-88页

作者：尚宜星卢克鹏肖淑娜河南科技大学第一附属医院药学部洛阳471000

目的:探讨低剂量利伐沙班与低分子量肝素钙治疗急性肺栓塞患者的疗效差异。方法:选取2021年2月~2022年2月期间于某院诊治的120例急性肺栓塞患者作为研究对象,根据随机数字表法分为低剂量利伐沙班组(A组)与低分子量肝素钙组(B组),每组60... 详细信息

目的:探讨低剂量利伐沙班与低分子量肝素钙治疗急性肺栓塞患者的疗效差异。方法:选取2021年2月~2022年2月期间于某院诊治的120例急性肺栓塞患者作为研究对象,根据随机数字表法分为低剂量利伐沙班组(A组)与低分子量肝素钙组(B组),每组60例。所有患者入院后均给予常规对症治疗,A组在常规对症治疗基础上口服利伐沙班片,B组在常规对症治疗基础上皮下注射低分子量肝素钙注射液,两组均连续治疗3个月。比较两组患者临床疗效、凝血功能指标[活化部分凝血活酶时间(APTT)、纤维蛋白原(FIB)和凝血酶原时间(PT)]、肺功能指标[用力肺活量占预计值百分比(FVC%pred)、第1秒用力呼气容积(FEV1)及FEV1占预计值百分比(FEV1%pred)]、动脉血气分析指标[动脉血氧分压(PaO_(2))、动脉血二氧化碳分压(PaCO_(2))]及不良反应发生情况。结果:治疗后,A组患者治疗总有效率(86.67%)高于B组(70.00%,P<0.05);两组患者APTT、PT均升高(P<0.05),且A组高于B组(P<0.05);两组患者FIB均降低(P<0.05),且A组低于B组(P<0.05);两组患者FVC%pred、FEV1、FEV1%pred均升高(P<0.05),且A组高于B组(P<0.05);两组患者PaO_(2)、PaCO_(2)均改善(P<0.05),且A组改善更显著(P<0.05);A组患者治疗期间不良反应总发生率(6.67%)低于B组(26.67%,P<0.05)。结论:低剂量利伐沙班与低分子量肝素钙均可有效改善急性肺栓塞患者的凝血功能、肺功能,且低剂量利伐沙班的临床疗效较低分子量肝素钙更佳,患者不良反应发生率更低。

关键词：急性肺栓塞利伐沙班低分子量肝素钙低剂量凝血功能肺功能动脉血气分析

Simultaneously Improving Mechanical Properties and Stress Corrosion Cracking Resistance of High-Strength Low-Alloy Steel via Finish Rolling within Non-recrystallization Temperature

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Acta Metallurgica Sinica(English Letters) 2021年第4期34卷 565-578页

作者： Hongchi Ma Baijie Zhao Yi Fan Kui xiao Jinbin Zhao Xuequn cheng xiaogang Li Key Laboratory for Corrosion and Protection(MOE) Institute for Advanced Materials and TechnologyUniversity of Science and Technology BeijingBeijing100083China Jiangsu Key Laboratory for Premium Steel Materials Nanjing Iron&Steel United Co.Ltd.Nanjing210035China State Key Laboratory of Metal Material for Marine Equipment and Application AnsteelAnshan114021China

The effect of hot rolling process on microstructure evolution,mechanical properties and stress corrosion cracking(SCC)resistance of high-strength low-alloy(HSLA)steels was investigated by varying the finish rolling temperature(FRT)and total rolling *** results revealed granular bainite with large equiaxed grains was obtained by a total rolling reduction of60%with the FRT of 950℃(within recrystallization temperature T_(r)).The larger grain size and much less grain boundaries should account for the relatively lower strength and SCC resistance.A larger rolling reduction of 80% under the same FRT resulted in the formation of massive martensite-austenite(M/A)constituents and resultant low ductility and SCC *** contrast,a good combination of strength,ductility and SCC resistance was obtained via 80% rolling reduction with the FRT of 860℃(within non-recrystallization temperature T_(nr)),probably because of the fine grain size and M/A constituents,as well as a high density of grain boundary network.

关键词： High-strength low-alloy(HSLA)steel Finish rolling temperature Non-recrystallization temperature Stress corrosion cracking(SCC) Grain boundary character Martensite-austenite(m/a)constituents

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基于UTAUT理论的高校快递包装回收研究

绿色包装 2024年第1期 31-35页

作者：宋璐君李俊翔彭晓斌电子科技大学中山学院广东中山528402 中石油燃料油有限责任公司华南销售分公司广东广州510235

快递包装回收不仅能减少资源浪费,还能降低环境污染。本文从大学生的快递包装处理习惯出发,采用问卷调查、实地考察方法,对大学生的物流快递包装回收意愿、行为习惯进行调研,根据UTAUT模型的绩效影响、社会条件、促进条件、努力期望、... 详细信息

快递包装回收不仅能减少资源浪费,还能降低环境污染。本文从大学生的快递包装处理习惯出发,采用问卷调查、实地考察方法,对大学生的物流快递包装回收意愿、行为习惯进行调研,根据UTAUT模型的绩效影响、社会条件、促进条件、努力期望、行为意愿五大主要因素,用线性回归的方法对问卷收集来的数据进行分析,发现高校校园快递包装回收存在回收方法单一、宣传力度小、担心增加不明收费等问题,并提出增加回收激励、扩展宣传渠道、严格保密学生隐私等针对性建议,以期推动校园快递包装回收的发展。

关键词： UTAUT理论回收物流包装快递包装

Modelling on seasonal lake ice evolution in central Asian arid climate zone: a case study

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Advances in Polar Science 2021年第4期32卷 356-363页

作者： LU peng Bin cheng Matti LEPPÄRANTA LI Zhijun State Key Laboratory of Coastal and Offshore Engineering Dalian University of TechnologyDalian 116081China Finnish Meteorological Institute Helsinki Fi-00101Finland University of Helsinki Helsinki Fi-00014Finland

The seasonal cycle of ice thickness and temperature in Lake Wuliangsuhai,a typical shallow lake in the central Asian arid climate zone,was simulated using the HIGHTSI model and the MERRA-2 data as the meteorological *** average ice growth rate was 0.64 cm·d^(−1) and −1.65 cm·d^(−1) for the growth and melting stage of the ice cover,*** ice thickness agreed well with the field observations conducted in winter 2017,with a correlation coefficient of *** ice temperature field also agreed with observations in both daily variations and the vertical profile,and a better agreement in the daily amplitude and profile shape of ice temperature could be achieved if field data on physical properties of snow cover andmelting ice were *** study proved the feasibility of both the HIGHTSI model and the MERRA-2 data for modeling the ice cover evolution in Lake Wuliangsuhai,providing a basis for a deep insight into the difference of lake ice evolution between central Asian arid climate zone and polar/sub-polar regions.

关键词： lake ice HIGHTSI model ice thickness ice temperature