检索结果-南通市图书馆

Chinese Medical Sciences Journal 2006年第2期21卷 90-94页

作者： Wen-hui Li Xin-hua xiao Qi sun Guo-hua Yang Heng Wang Department of Endocrinology Peking Union Medical College Hospital Chinese Academy of Medical Sciences ＆ Peking Union Medical College Beijing 100730

Objective To investigate the relationship between glycosylated hemoglobin A1 c （HbA1 c） and blood glucose levels of eight different points throughout the day in well-glycemic-controlled medical nutrition therapy （MNT） alone type 2 diabetic pafients. Methods Data were collected as＂ capillary blood glucose value of eight different sample points among sixteen observing days in thirty MNT alone type 2 diabetic patients. The correlation between HbAI c and capillary blood glucose value was evaluated by Pearson＇s correlation method. Results The r-values between HbA1c and capillary blood glucose of 3：00, 6：00, and bedtime （22：00-23：00） were 0. 81,0. 79, and 0. 78, respectively（P 〈0. 001 ）. The best correlation was found between the mean value of 8- point blood glucose value throughout the day and HbA1c （ r=0. 84, P 〈0. 001 ）. Conclustion Fasting blood glucose and postabsorptive blood glucose have better correlations with HbAlc compared with other points in this group of well-glycemic-controlled MNT alone type 2 diabetic patients.

关键词： type 2 diabetes medical nutrition therapy hemoglobin Alc blood glucose

Protein surface recognition of the novel tetra-carboxylphenyl calix[4]arene to cytochrome c

在线全文

学校读者我要写书评

暂无评论

Chinese Chemical Letters 2008年第11期19卷 1341-1344页

作者： Wen Ting An Yong Jiao xiao hua sun Chuan Dong Shao Min Shuang Ping Fang Xia Man Shing Wong Research Center of Environmental Science and Engineering School of Chemistry and Chemical Engineering Shanxi University Taiyuan 030006 China Department of Chemistry Hong Kong Baptist University Kowloon Tong Hongkong S.A.R. China

The interaction of the novel tetra-carboxylphenyl calix[4]arene （TCPC） with the bovine heart cytochrome c （Cc） was first investigated by fluorescence spectroscopy and molecular modeling methods. The formation of a stable 1：1 complex was monitored by fluorescence titration, and its binding constant is 1.916 ×10^7 L mol^-1. Molecular modeling reveals the recognition mechanism of TCPC to the Cc surface, that is, the electrostatic interaction drives TCPC to the Cc surface, and the van der Waals interaction orientates TCPC parallel to the cleft of Cc.

关键词： Tetra-carboxylphenyl calixarene Cytochromc c Protein surface recognition Fluorescence spectroscopy Molecular modeling

中国近古新建都城的形态与规划——从元明中都的考古复原和对比分析出发

在线全文

学校读者我要写书评

暂无评论

城市规划 2018年第8期42卷 57-65页

作者：陈筱孙华浙江大学文化遗产研究院北京大学考古文博学院

元中都和明中都是中国近古时期完全新建于生地的两座大型城址,它们与元大都、明清北京有密切的承继关系,由于尚未完工就遭废置,又长期保存于荒野或农村,城市遗迹保存得比较完整。本文根据对元中都考古数据的复原以及明中都设计尺度的分... 详细信息

元中都和明中都是中国近古时期完全新建于生地的两座大型城址,它们与元大都、明清北京有密切的承继关系,由于尚未完工就遭废置,又长期保存于荒野或农村,城市遗迹保存得比较完整。本文根据对元中都考古数据的复原以及明中都设计尺度的分析,首先从营建背景和城市形态等视角对元明中都进行了比较;进一步,推测了元明中都的原初设计方案,将它们与《考工记·匠人》城市思想从边界、出入口、核心功能区以及整合结构等4个方面进行比较,考察了《考工记》对中国近古都城规划思想影响的变化趋势。

关键词：元中都明中都都城考工记规划思想

Imagery perspective among young athletes: Differentiation between external and internal visual imagery

在线全文

学校读者我要写书评

暂无评论

Journal of Sport and Health Science 2016年第2期5卷 211-218页

作者： Qiu-hua Yu Amy S.N.Fu Adeline Kho Jie Li xiao-hua sun Chetwyn C.H.Chan Applied Cognitive Neuroscience Laboratory Department of Rehabilitation Sciences The Hong Kong Polytechnic University Department of Rehabilitation Sciences The Hong Kong Polytechnic University Metacognition Developmental Centre Department of Science and Education Guangdong Provincial Bureau of Sports Guangdong Institute of Sport

Purpose： This study aimed to investigate the construct of external visual imagery （EVI） vs. internal visual imagery （IV/） by comparing the athletes＇ imagery ability with their levels of skill and types of sports. Methods： Seventy-two young athletes in open （n = 45） or closed （n = 27） sports and with different skill levels completed 2 custom-designed tasks. The EVI task involved the subject generating and visualizing the rotated images of different body parts, whereas the IVI task involved the subject visualizing himself or herself performing specific movements. Results： The significant Skill-Level x Sport Type interactions for the EVI task revealed that participants who specialized in open sports and had higher skill-levels had a higher accuracy rate as compared to the other subgroups. For the IVI task, the differences between the groups were less clear： those with higher skill-levels or open sports had a higher accuracy rate than those with lower skill-levels or closed sports. Conclusion： EVI involves the visualization of others and the environment, and would be relevant to higher skill-level athletes who engage in open sports. IVI, in contrast, tends to be more self-oriented and would be relevant for utilization by higher skill-level athletes regardless of sport type.

关键词： External visual imagery Internal visual imagery Open sports Skills Youth

Medical expenditure for esophageal cancer in China:a 10-year multicenter retrospective survey(2002-2011)

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2017年第11期36卷 548-559页

作者： Lan-Wei Guo Hui-Yao huang Ju-Fang Shi Li-Hong Lv Ya-Na Bai A-Yan Mao Xian-Zhen Liao Guo-Xiang Liu Jian-Song Ren xiao-Jie sun Xin-Yu Zhu Jin-Yi Zhou Ji-Yong Gong Qi Zhou Lin Zhu Yu-Qin Liu Bing-Bing Song Ling-Bin Du xiao-Jing Xing Pei-An Lou xiao-hua sun xiao Qi Shou-Ling Wu Rong Cao Li Lan Ying Ren Kai Zhang Jie He Jian.Gong Zhang Min Dai Department of Cancer Epidemiology Henan Office for Cancer Control and Research The Affiliated Cancer Hospital of Zhengzhou University Henan Cancer Hospital No. 127 Dongming Road Zhengzhou 450008 Henan P. R China Program Office for Cancer Screening in Urban China Cancer Hospital Chinese Academy of Medical Sciences (CAMS) Peking Union Medical College National Cancer Center of China No. 17 Panjiayuannanli Chaoyang District Beijing 100021 P. R. China Department of Human Resources The Affiliated Cancer Hospital of Zhengzhou University Henan Cancer Hospital Zhengzhou 450008 Henan P. R. China Institute of Epidemiology and Health Statistics Lanzhou University Lanzhou 730000 Gansu P. R. China Public Health Information Research Office Institute of Medical Information Chinese Academy of Medical Sciences (CAMS) Beijing 100020 P. R. China Hunan Office for Cancer Control and Research Hunan Provincial Cancer Hospital Changsha 410006 Hunan P. R. China Department of Health Economics School of Health Management Harbin Medical University Harbin 150081 Heilongjiang P. R. China Center for Health Management and Policy Key Lab of Health Economics and Policy Shandong University Jinan 250012 Shandong P. R. China Institute of Chronic Non.Communicable Diseases Prevention and Control Jiangsu Provincial Center for Disease Control and Prevention Nanjing 210009 Jiangsu P. R. China Science and Education Department Public Health Division Shandong Tumor Hospital Jinan 250117 Shandong P. R. China Chongqing Office for Cancer Control and Research Chongqing Cancer Hospital Chongqing 400030 P. R. China Teaching and Research Department Affiliated Cancer Hospital of Xinjiang Medical University ürümqi 830011 Xinjiang P. R. China Cancer Epidemiology Research Center Gansu Provincial Cancer Hospital Lanzhou 730050 Gansu P. R. China Heilongjiang Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical University Harbin 150081 Heilongjiang P R. China Zhejiang Office for Cancer

Background: Esophageal cancer is associated with substantial disease burden in China, and data on the economic burden are fundamental for setting priorities in cancer interventions. The medical expenditure for the diagnosis and treatment of esophageal cancer in China has not been fully quantified. This study aimed to examine the medical expenditure of Chinese patients with esophageal cancer and the associated ***: From 2012 to 2014, a hospital-based multicenter retrospective survey was conducted in 37 hospitals in 13 provinces/municipalities across China as a part of the Cancer Screening Program of Urban China. For each esophageal cancer patient diagnosed between 2002 and 2011, clinical information and expense data were extracted by using structured questionnaires. All expense data were reported in Chinese Yuan(CNY; 1 CNY = 0.155 USD) based on the2011 value and inflated using the year-specific health care consumer price index for ***: A total of 14,967 esophageal cancer patients were included in the analysis. It was estimated that the overall average expenditure per patient was 38,666 CNY, and an average annual increase of 6.27% was observed from 2002(25,111 CNY) to 2011(46,124 CNY). The average expenditures were 34,460 CNY for stage Ⅰ,39,302 CNY for stage Ⅱ,40,353 CNY for stage Ⅲ, and 37,432 CNY for stage IV diseases(P < 0.01). The expenditure also differed by the therapy type, which was 38,492 CNY for surgery, 27,933 CNY for radiotherapy, and 27,805 CNY for chemotherapy(P < 0.05).Drugs contributed to 45.02% of the overall ***: These conservative estimates suggested that medical expenditures for esophageal cancer in China substantially increased in the last 10 years, treatment for early-stage esophageal cancer costs less than that for advanced cases, and spending on drugs continued to account for a considerable proportion of the overall expenditure.

关键词： Esophageal neoplasms Medical expenditure Diagnosis and treatment China

Expenditure and financial burden for the diagnosis and treatment of colorectal cancer in China:a ***,multicenter,cross-sectional survey

在线全文

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2017年第8期36卷 352-366页

作者： Hui-Yao huang Ju-Fang Shi Lan-Wei Guo Ya-Na Bai Xian-Zhen Liao Guo-iangLiu A-Yan Mao Jian-Song Ren xiao-Jie sun Xin-Yu Zhu Le Wang Bing-Bing Song Ling-Bin Du Lin Zhu Ji-Yong Gong Qi Zhou Yu-Qin Liu Rong Cao Ling Mai Li Lan xiao-hua sun Ying Ren Jin-Yi Zhou Yuan-Zheng Wang xiao Qi Pei-An Lou Dian Shi Ni Li Kai Zhang Jie He Min Dai Program Office for Cancer Screening in Urban China National Cancer Center/Cancer HospitalChinese Academy of Medical SciencesPeking Union Medical College17 South Panjiayuan LaneChaoyang DistrictBeijing 100021P.R.China Department of Cancer Epidemiology Henan Cancer HospitalAffiliated Cancer Hospital of Zhengzhou UniversityZhengzhouHenan 450008P.R.China Institute of Epidemiology and Health Statistics Lanzhou UniversityLanzhouGansu 730000P.R.China Hunan Office for Cancer Control and Research Hunan Provincial Cancer HospitalChangshaHunan 410006P.R.China Department of Health Economics School of Health ManagementHarbin Medical UniversityHarbinHeilongjiang 150081P.R.China Public Health Information Research Office Institute of Medical InformationChinese Academy of Medical SciencesBeijing 100020P.R.China Center for Health Management and Policy Key Lab of Health Economics and PolicyShandong UniversityJinanShandong 250012P.R.China Heilongjiang Office for Cancer Control and Research Affiliated Cancer Hospital of Harbin Medical UniversityHarbinHeilongjiang 150081P.R.China Zhejiang Office for Cancer Control and Research Zhejiang Cancer HospitalHangzhouZhejiang 310022P.R.China Teaching and Research Department Affiliated Cancer Hospital of Xinjiang Medical UniversityürümqiXinjiang 830011P.R.China Science and Education Department of Public Health Division Shandong Tumor HospitalJinanShandong 250117P.R.China Chongqing Office for Cancer Control and Research Chongqing Cancer HospitalChongqing 400030P.R.China Cancer Epidemiology Research Center Gansu Provincial Cancer HospitalLanzhouGansu 730050P.R.China Department of Health Policy and Economic Research Guangdong Provincial Institute of Public HealthGuangzhouGuangdong 511430P.R.China Department of Institute of Tumor Research Henan Cancer HospitalAffiliated Cancer Hospital of Zhengzhou UniversityZhengzhouHenan 450008P.R.China Institute of Chronic Disease Prevention and Control Harbin Center for Disease Control and PreventionHarbinHei

Background: The increasing prevalence of colorectal cancer(CRC) in China and the paucity of information about relevant expenditure highlight the necessity of better understanding the financial burden and effect of CRC diagnosis and treatment. We performed a survey to quantify the direct medical and non-medical expenditure as well as the resulting financial burden of CRC patients in ***: We conducted a multicenter, cross-sectional survey in 37 tertiary hospitals in 13 provinces across China between 2012 and 2014. Each enrolled patient was interviewed using a structured questionnaire. All expenditure data were inflated to the 2014 Chinese Yuan(CNY; 1 CNY = 0.163 USD). We quantified the overall expenditure and financial burden and by subgroup(hospital type, age at diagnosis, sex, education, occupation, insurance type, household income, clinical stage, pathologic type, and therapeutic regimen). We then performed generalized linear modeling to determine the factors associated with overall ***: A total of 2356 patients with a mean age of 57.4 years were included, 57.1 % of whom were men; 13.9% of patients had stage I cancer; and the average previous-year household income was 54,525 *** overall average direct expenditure per patient was estimated to be 67,408 CNY, and the expenditures for stage Ⅰ, Ⅱ, Ⅲ, and Ⅳ disease were 56,099 CNY, 59,952 CNY, 67,292 CNY, and 82,729 CNY, respectively. Non-medical expenditure accounted for 8.3%of the overall expenditure. The 1-year out-of-pocket expenditure of a newly diagnosed patient was 32,649 CNY, which accounted for 59.9% of their previous-year household income and caused 75.0% of families to suffer an unmanageable financial burden. Univariate analysis showed that financial burden and overall expenditure differed in almost all subgroups(P < 0.05), except for sex. Multivariate analysis showed that patients who were treated in specialized hospitals and those who were diagnosed with adenocarcinoma or diagno

关键词： Colorectal neoplasms Direct expenditure Financial burden China

胚胎冷冻10年复苏并行囊胚培养后再次冷冻并复苏移植后获妊娠1例报道

在线全文

学校读者我要写书评

暂无评论

生殖与避孕 2016年第10期36卷 864-867页

作者：陈海啸孙小花解放军第一七四医院生殖医学中心厦门361000

目的:探讨在体外受精-胚胎移植(in-vitro fertilization-embryo transfer,IVF-ET)过程中,卵裂期胚胎冷冻10年后解冻复苏再移植成功妊娠的可能性。方法:1例患者卵裂期胚胎冷冻10年后解冻复苏并行囊胚培养,获得囊胚后再次冷冻1年后复苏,... 详细信息

目的:探讨在体外受精-胚胎移植(in-vitro fertilization-embryo transfer,IVF-ET)过程中,卵裂期胚胎冷冻10年后解冻复苏再移植成功妊娠的可能性。方法:1例患者卵裂期胚胎冷冻10年后解冻复苏并行囊胚培养,获得囊胚后再次冷冻1年后复苏,行囊胚移植。结果:该患者移植后顺利获得临床妊娠,并于孕38周剖宫产一健康男婴。结论:长期保存的胚胎解冻后重新冷冻对最终获得妊娠依然有价值;冷冻胚胎囊胚培养有助于提高卵裂期胚胎冷冻复苏后的利用价值及提高胚胎着床率。

关键词：胚胎玻璃化冷冻冷冻胚胎复苏囊胚培养

在线全文

学校读者我要写书评

暂无评论

新时期公共图书馆为弱势群体服务的若干探索

图书馆论坛 2004年第3期24卷 125-127,68页

作者：黄小华广东省立中山图书馆广东广州510110

阐明了在全面建设小康社会奋斗过程中 ,为弱势群体服务应当是公共图书馆的必然选择和重要职能。

关键词：公共图书馆弱势群体服务价值观全面发展教育图书借阅图书流通站

在线全文

学校读者我要写书评

暂无评论

论21世纪的女性馆员

图书馆论坛 2003年第4期23卷 37-39,76页

作者：黄小华广东省立中山图书馆广东广州510110

通过对 2 1世纪图书馆特征以及女性馆员现状、优势的分析 ,论述了女性馆员需完善自我 ,提高整体素质 ,以推动图书馆事业持续快速发展。

关键词： 21世纪图书馆女性馆员发展优势素质计算机化网络化人才专家化服务方式

Prospects of elafibranor in treating alcohol-associated liver diseases

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第2期31卷 132-137页

作者： Wei-Tong Cui hua-Ru Xue Dian-Fang Wei xiao-Yu Feng Kai Wang School of Basic Medicine Qilu Medical UniversityZibo 255300Shandong ProvinceChina School of Medical Imaging Qilu Medical UniversityZibo 255300Shandong ProvinceChina

Alcohol-related liver disease(ALD),which is induced by excessive alcohol con-sumption,is a leading cause of liver-related morbidity and *** pa-tients exhibit a spectrum of liver injuries,including hepatic steatosis,inflam-mation,and fibrosis,similar to symptoms of nonalcohol-associated liver diseases such as primary biliary cholangitis,metabolic dysfunction-associated steatotic liver disease,and nonalcoholic *** has been approved for the treatment of primary biliary cholangitis and has been shown to improve symptoms in both animal models and in vitro cell models of metabolic dysfunc-tion-associated steatotic liver disease and nonalcoholic ***,the efficacy of elafibranor in treating ALD remains *** this article,we comment on the recent publication by Koizumi et al that evaluated the effects of elafibranor on liver fibrosis and gut barrier function in an ALD mouse *** findings indicate the potential of elafibranor for ALD treatment,but further experimental investigations and clinical trials are warranted.

关键词： Elafibranor Alcohol-associated liver diseases Peroxisome proliferator-activated receptor Lipid Apoptosis Steatosis Inflammation Fibrosis