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DROPWISE　CONDENSATION　OF　STEAM　ON　ALLOY　SURFACES　OBTAINED　BY　ION－IMPLANTATION　TECHNIQUE

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高校化学工程学报 1994年第S1期8卷 96-103页

作者： yong-ji song and xiao-guang ren (Liaoyang Petrochem Engineering Institute Liaoyang 111003 CHINA)

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关键词： IMPLANTATION TECHNIQUE OBTAINED ALLOY BY

Visualizing phase transition of upper critical solution temperature (UCST) polymers with AIE

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Science China Chemistry 2021年第3期64卷 403-407页

作者： yong-guang jia Kai-Feng Chen Meng Gao Sa Liu jin Wang xiaohui Chen Lin Wang Yunhua Chen Wenjing song Huatang Zhang Li ren xiao-Xia Zhu Ben Zhong Tang School of Materials Science and Engineering National Engineering Research Center for Tissue Restoration and ReconstructionKey Laboratory of Biomedical Engineering of Guangdong ProvinceKey Laboratory of Biomedical Materials and Engineering of the Ministry of EducationInnovation Center for Tissue Restoration and ReconstructionSouth China University of TechnologyGuangzhou 510641China School of Chemical Engineering and Light Industry Guangdong University of TechnologyGuangzhou 510006China Departement de Chimie Universite de MontrealC.P.6128Succ.Centre-villeMontrealQCH3C 3J7Canada AIE Institute Center for Aggregation-Induced EmissionKey Laboratory of Luminescence from Molecular Aggregates of Guangdong ProvinceState Key Laboratory of Lu minescent Materials and DevicesSouth China University of TechnologyGuangzhou 510640China Department of Chemistry Hong Kong Branch of Chinese National Engineering Research Centre for Tissue Restoration and ReconstructionInstitute for Advanced StudyDepartment of Chemical and Biological EngineeringThe Hong Kong University of Science&TechnologyHong KongChina

The stimuli-responsive polymers with upper critical solution temperatures(UCST) are highly attractive for drug delivery applications. However, the phase transition process of UCST polymer is usually characterized by turbidity measurement and electron microscopy, which are significantly restricted by low sensitivity and static observation. In contrary, the fluorescence technique has significant advantages in terms of high sensitivity, easy operation, and dynamic observation. However, the conventional fluorophores suffer from the drawbacks of aggregation-caused quenching(ACQ) after being encapsulated by UCST polymers, which are not suitable for direct visualization of the phase transition process. To tackle this challenge, we herein developed a series of UCST polymers based on polyacrylamides decorated with bile acid and aggregation-induced emission(AIE)-active tetraphenylethene(TPE) groups, which can be used for direct fluorescence monitoring of the phase transition process. Moreover, the AIE-active UCST polymers can serve as drug carriers, which can not only monitor the drug release process under thermal stimuli, but also verify the drug release by fluorescence recovery after thermal stimuli. It is expected that the AIE-active UCST polymers with self-monitoring ability are promising for biomedical applications.

关键词： upper critical solution temperatures aggregation-induced emission phase transition process drug release monitoring bile acid

Two-photon Up-conversion Luminescent Properties of HMASPS and HEASPS in Three Different Polymer Matrices

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Chinese Chemical Letters 2002年第5期13卷 452-455页

作者： Yan ren xiao Qiang YU Dong WANG guang yong ZHOU Zhi Qiang LIU Yu Fang ZHOU Xian ZHAO Zong Shu SHAO ji Yang WANG Min Hua jiANG State Key Laboratory of Crystal Materials Shandong UniversityJinan 250100

Three dye-doped polymer rods in different matrices were synthesized in which weak hydrogen bond, strong hydrogen bond and covalent bond existed between the dye and the polymer chain. And the two-photon up-conversion... 详细信息

关键词： Two-photon up-conversion lasing solid-state laser dye.

Characterization of CD4~+ T Cell Responses in Mice Infected with Schistosoma japonicum

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Acta Biochimica et Biophysica Sinica 2006年第5期38卷 327-334页

作者： Min-Jun ji Chuan SU yong WANG Hai-Wei WU xiao-Ping CAI guang-Fu LI Xiang ZHU Xin-Jun WANG Zhao-song ZHANG Guan-Ling WU~* Department of Pathogen Biology,Nanjing Medical University,Nanjing 210029,China Department of Pathogen Biology Nanjing Medical UniversityNanjing 210029 China

To better understand the interaction between Schistosoma japonicum and its murine host,wecharacterized the immune response of CD4~+ T cells generated during an experimental *** infectionbased on different key aspects,from gene expression to cell *** oligonucleotide microarrayswere used to compare gene expression profiles of CD4~+ T cells from spleens of mice at 0,3,6 and 13weeks *** cytometry analysis was used to determine type 1 and type 2 cytokine-secretingCD4~+ T cells,to test apoptosis of CD4~+ T cells and to count CD4~+CD25~+ T cells,a kind of regulatorysubpopulation of CD4~+ T *** percentage of interleukin-4-producing CD4~+ T cells was found to bemuch higher than that of γ-interferon-producing cells,especially after stimulation with *** eggantigen,which was consistent with type 1 and type 2 cytokine gene expression in the *** also showed that *** induced the increased expression of Th2 response-related genes,whereassome transcripts related to the Th1 responsive pathway were *** cytometry analysis showeda marked increase in the apoptotic CD4~+ T cells from 6 weeks post-infection and in the ratio of CD4~+CD25~+to CD4~+ T cells in infected mice after 13 *** therefore concluded that experimental infection of micewith *** resulted in a Th2-skewed immune response,which was to a great extent monitored bythe immune regulatory network,including cytokine cross-modulation,cell apoptosis and the subpopulationof regulatory cells.

关键词： Schistosoma japonicum CD4~+ T cell immune deviation immune regulatory network

Identification of Immunodominant Th1-type T cell Epitopes from Schistosoma japonicum 28 kDa Glutathione-S-transferase,a Vaccine Candidate

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Acta Biochimica et Biophysica Sinica 2005年第11期37卷 751-758页

作者： guang-Fu LI yong WANG Zhao-song ZHANG Xin-Jun WANG Min-Jun ji Xiang ZHU Feng LIU xiao-Ping CAI Hai-Wei WU Guan-Ling WU Department of Pathogenic Biology,Nanjing Medical University,Nanjing 210029,China Department of Pathogenic Biology Nanjing Medical UniversityNanjing 210029 China

Th1-type cytokines produced by the stimulation of Th1-type epitopes derived from definedschistosome-associated antigens are correlated with the development of resistance to the parasite *** mansoni 28 kDa glutathione-S-transferase(Sm28GST),a major detoxification enzyme,hasbeen recognized as a vaccine candidate and a phase Ⅱ clinical trial has been carried *** immunizedwith recombinant Schistosoma japonicum 28GST(Sj28GST)have shown immune protection against theparasite *** the present study,six candidate peptides(P1,P2,P3,P4,P7 and P8)from Sj28GSTwere predicted,using software,to be T cell epitopes,and peptides P5 and P6 were designed by extendingfive amino acids at the N-terminal and C-terminal of P1,*** peptide 190-211 aa in Sj28GSTcorresponding to the Th1-type epitope(190-211 aa)identified from Sm28GST was selected and named *** nine candidate peptides were synthesized or produced as the fusion protein with thioredoxin in thepET32c(+)/BL21(DE3)*** capacity to induce a Th1-type response in vitro was measured usinglymphocyte proliferation,cytokine detection experiments and flow *** results showed that P6(73-86 aa)generated the strongest stimulation effect on T cells among the nine candidate peptides,and drovethe highest level of IFN-γ and ***,P6 is a functional Th1-type T cell epitope that is differentfrom that in Sm28GST,and will be useful for the development of effective vaccines which can triggeracquired immunity against ***,our strategy of identifying the Th1-type epitope by acombination of software prediction and experimental confirmation provides a convenient and cost-savingalternative approach to previous methods.

关键词： Schistosoma japonicum epitope Sj28GST Th1 epitope IFN-γ

Changes in the ground surface temperature in permafrost regions along the Qinghaie-Tibet engineering corridor from 1900 to 2014:A modified assessment of CMIP6

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Advances in Climate Change Research 2023年第1期14卷 85-96页

作者： Zan-Pin XING Lin ZHAO Lei FAN Guo-jie HU De-Fu ZOU Chong WANG Shu-Ci LIU Er-ji DU Yao xiao ren LI guang-Yue LIU yong-Ping QIAO jian-Zong SHI Cryosphere Research Station on the QinghaieTibet Plateau State Key Laboratory of Cryospheric ScienceNorthwest Institute of Eco-Environment and ResourceChinese Academy of SciencesLanzhou 730000China University of Chinese Academy of Sciences Beijing 100049China School of Geographical Sciences Nanjing University of Information Science&TechnologyNanjing 210044China Chongqing jinfo Mountain Karst Ecosystem National Observation and Research Station School of Geographical SciencesSouthwest UniversityChongqing 400715China Department of Environment and Science Queensland GovernmentBrisbaneQLD 4102Australia

Numerous studies were published in the last two decades to evaluate and project the permafrost changes in its thermal state,mainly based on the soil temperature datasets from the Coupled Model Intercomparison Project(CMIP),and discuss the impacts of permafrost changes on regional hydrological,ecological and climatic systems and even carbon ***,limited monitored soil temperature data are available to validate the CMIP outputs,resulting in the over-projection of future permafrost changes in CMIP3 and ***,future permafrost changes in CMIP6,particularly over the QinghaieTibet Plateau(QTP),where permafrost covers more than 40%of its territory,are still un*** address this gap,we evaluated and calibrated the monthly ground surface temperature(GST;5 cm below the ground surface),which was often used as the upper boundary to simulate and project permafrost changes derived from 19 CMIP6 Earth System Models(ESMs)against in situ measurements over the *** generated the monthly GST series from 1900 to 2014 for five sites based on the linear calibration models and validated them through the three other sites using the same calibration *** showed that all of the ESMs could capture the dynamics of in situ GST with high correlations(r>0.90).However,large errors were detected with a broad range of centred root-mean-square errors(1.14-4.98℃).The Top 5 model ensembles(MME5)performed better than most individual ESMs and averaged multi-model ensembles(MME19).The calibrated GST performed better than the GST obtained from *** annual and seasonal GSTs exhibited warming trends with an average annual rate of 0.04℃ per decade in the annual *** average seasonal warming rate was highest in winter and spring and lowest in *** reconstructed GST data series could be used to simulate the long-term permafrost temperature over the QTP.

关键词： Ground surface temperature CMIP6 Cold bias Permafrost Qinghaie-Tibet engineering corridor

Application of neuroendoscopic surgical techniques in the assessment and treatment of cerebral ventricular infection

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Neural Regeneration Research 2019年第12期14卷 2095-2103页

作者： Feng Guan Wei-Cheng Peng Hui Huang Zu-Yuan ren Zhen-Yu Wang ji-Di Fu Ying-Bin Li Feng-Qi Cui Bin Dai guang-Tong Zhu Zhi-yong xiao Bei-Bei Mao Zhi-Qiang Hu Department of Neurosurgery Beijing Shijitan Hospital Capital Medical University Beijing China Department of Neurosurgery Peking Union Medical College Hospital Beijing China Department of Neurosurgery Peking University Third Hospital Peking University Beijing China Department of Neurosurgery Beijing Tongren Hospital Capital Medical University Beijing China Department of Neurosurgery the Second Affiliated Hospital of Nanjing Medical University Nanjing Jiangsu Province China Department of Neurosurgery Beijing Liangxiang Hospital Beijing China

Cerebral ventricular infection (CVI) is one of the most dangerous complications in neurosurgery because of its high mortality and disability rates. Few studies have examined the application of neuroendoscopic surgical techniques (NESTs) to assess and treat CVI. This multicenter, retrospective study was conducted using clinical data of 32 patients with CVI who were assessed and treated by NESTs in China. The patients included 20 men and 12 women with a mean age of 42.97 years. NESTs were used to obliterate intraventricular debris and pus, fenestrate or incise the intraventricular compartment and reconstruct cerebrospinal fluid circulation, and remove artificial material. Intraventricular irrigation with antibiotic saline was applied after neuroendoscopic surgery (NES). Secondary hydrocephalus was treated by endoscopic third ventriculostomy or a ventriculoperitoneal shunt. Neuroendoscopic findings of CVI were used to classify patients into Grade Ⅰ(n = 3), Grade Ⅱ(n = 13), Grade Ⅲ(n = 10), and Grade Ⅳ(n = 6) CVI. The three patients with grade ⅠCVI underwent one NES, the 23 patients with grade Ⅱ/Ⅲ CVI underwent two NESs, and patients with grade Ⅳ CVI underwent two (n = 3) or three (n = 3) NESs. The imaging features and grades of neuroendoscopy results were positively related to the number of neurosurgical endoscopic procedures. Two patients died of multiple organ failure and the other 30 patients fully recovered. Among the 26 patients with secondary hydrocephalus, 18 received ventriculoperitoneal shunt and 8 underwent endoscopic third ventriculostomy. There were no recurrences of CVI during the 6- to 76-month follow-up after NES. Application of NESTs is an innovative method to assess and treat CVI, and its neuroendoscopic classification provides an objective, comprehensive assessment of CVI. The study trial was approved by the Institutional Review Board of Beijing Shijitan Hospital, Capital Medical University, China.

关键词： nerve regeneration neuroendoscopy surgery cerebral ventricular infection assessment treatment hydrocephalus irrigation neural regeneration

Causes and global,regional,and national burdens of traumatic brain injury from 1990 to 2019

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Chinese Journal of Traumatology 2024年第6期27卷 311-322页

作者： xiao-Fei Huang Shuai-Feng Ma Xu-Heng jiang ren-jie song Mo Li ji Zhang Tian-jing Sun Quan Hu Wen-Rui Wang An-yong Yu He Li Department of Emergency Surgery The Second Affiliated Hospital of Anhui Medical UniversityHefei230601China Department of Emergency Affiliated Hospital of Zunyi Medical UniversityZunyi563003Guizhou provinceChina

Purpose:Traumatic brain injury(TBI),currently a major global public health problem,imposes a significant economic burden on society and *** aimed to quantify and predict the incidence and severity of TBI by analyzing its incidence,prevalence,and years lived with disability(YLDs).The epidemiological changes in TBI from 1990 to 2019 were described and updated to provide a reference for developing prevention,treatment,and incidence-reducing measures for ***:A secondary analysis was performed on the incidence,prevalence,and YLDs of TBI by sex,age group,and region(n=21,204 countries and territories)between 1990 and 2019 using the Global Burden of Diseases,Injuries,and Risk Factors Study *** in the age-standardized incidence rate due to underlying causes of TBI and proportions of minor and moderate or severe TBI were also ***:In 2019,there were 27.16 million(95%uncertainty intervals(UI):23.36-31.42)new cases of TBI worldwide,with age-standardized incidence and prevalence rates of 346 per 100,000 population(95%UI:298-401)and 599 per 100,000 population(95%UI:573-627),*** 1990 to 2019,there were no significant trends in global age-standardized incidence(estimated annual percentage changes:-0.11%,95%UI:-0.18%--0.04%)or prevalence(estimated annual percentage changes:0.01%,95%UI:-0.04%-0.06%).TBI caused 7.08 million(95%UI:5.00-9.59)YLDs in 2019,with age-standardized rates of 86.5 per 100,000 population(95%UI:61.1-117.2).In 2019,the countries with higher incidence rates were mainly distributed in Central Europe,Eastern Europe,and *** 2019 global age-standardized incidence rate was higher in males than in *** 2019 global incidence of moderate and severe TBI was 182.7 per 100,000 population,accounting for 52.8%of all TBI,with falls and road traffic injuries being the main causes in most ***:The incidence of moderate and severe TBI was slightly higher in 2019,and TBI still accounts for a signi

关键词： Traumatic brain injury Global health Burden of disease

反相微乳液法制备铈锰取代六铝酸盐甲烷燃烧催化剂

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功能材料 2008年第1期39卷 75-78页

作者：宋永吉朱安民任晓光北京石油化工学院北京102617

研究了组成及温度对水/环己烷/TX-100+正戊醇体系反相微乳液区的影响,选择合适组成的反相微乳液做为合成介质,制备了BaMnCeAl10O19-δ六铝酸盐催化剂,研究了制备条件对催化剂样品的比表面积、结构及甲烷燃烧催化活性的影响。结果表明,... 详细信息

研究了组成及温度对水/环己烷/TX-100+正戊醇体系反相微乳液区的影响,选择合适组成的反相微乳液做为合成介质,制备了BaMnCeAl10O19-δ六铝酸盐催化剂,研究了制备条件对催化剂样品的比表面积、结构及甲烷燃烧催化活性的影响。结果表明,该体系反相微乳液区面积的变化受到组成和温度的影响,当n=3∶2、温度为25℃时,体系的反相微乳液区最大。油相和硝酸盐加入量的不同对催化剂的活性、粒径以及比表面积有较大的影响,油相用量增加、硝酸盐混合溶液用量的减少有利于所制备活性的提高以及比表面积的增加。在油相用量较大(硝酸盐混合溶液用量较小)的条件下,制备出的催化剂活性最高,其T10%、T50%和T90%分别达到456、582和698℃。

关键词：反相微乳液催化燃烧催化剂六铝酸盐甲烷