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Chinese Physics Letters 2018年第2期35卷 88-92页

作者： Ai-Xing Li Chun-Lan Mo Jian-Li Zhang xiao-Lan Wang xiao-ming wn Guang-Xu Wang Jun-Lin Liu Feng-Yi Jiang National Institute of LED on Silicon Substrate Nanchang University

In GaN-based green light-emitting diodes（LEDs） with and without Mg-preflow before the growth of p-Al GaN electron blocking layer（EBL） are investigated experimentally.A higher Mg doping concentration is achieved in the EBL after Mg-preflow treatment,effectively alleviating the commonly observed efficiency collapse and electrons overflowing at cryogenic ***,unexpected decline in quantum efficiency is observed after Mg-preflow treatment at room *** conclusions are drawn such that the efficiency decline is probably the result of different emission *** Mg doping concentration in the EBL after Mg-preflow treatment will make it easier for a hole to be injected into multiple quantum wells with emission closer to pGaN side through the（8-plane rather than the V-shape pits,which is not favorable to luminous efficiency due to the preferred occurrence of accumulated strain relaxation and structural defects in upper QWs closer to *** this framework,apparently disparate experimental observations regarding electroluminescence properties,in this work,are well reconciled.

关键词： GaN EBL Effect of Mg-Preflow for p-AlGaN Electron Blocking Layer on the Electroluminescence of Green LEDs with V-Shaped Pits

Enhancement of motor functional recovery in thoracic spinal cord injury: voluntary wheel running versus forced treadmill exercise

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Neural Regeneration Research 2025年第3期20卷 836-844页

作者： Do-Hun Lee Dan Cao Younghye Moon Chen Chen Nai-Kui Liu xiao-ming Xu Wei Wu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteIndiana University School of MedicineIndianapolisINUSA Department of Neurological Surgery Indiana University School of MedicineIndianapolisINUSA Department of Neuroscience Baylor College of MedicineHoustonTXUSA

Spinal cord injury necessitates effective rehabilitation strategies, with exercise therapies showing promise in promoting recovery. This study investigated the impact of rehabilitation exercise on functional recovery and morphological changes following thoracic contusive spinal cord injury. After a 7-day recovery period after spinal cord injury, mice were assigned to either a trained group(10 weeks of voluntary running wheel or forced treadmill exercise) or an untrained group. Bi-weekly assessments revealed that the exercise-trained group, particularly the voluntary wheel exercise subgroup, displayed significantly improved locomotor recovery, more plasticity of dopaminergic and serotonin modulation compared with the untrained group. Additionally, exercise interventions led to gait pattern restoration and enhanced transcranial magnetic motor-evoked potentials. Despite consistent injury areas across groups, exercise training promoted terminal innervation of descending axons. In summary, voluntary wheel exercise shows promise for enhancing outcomes after thoracic contusive spinal cord injury, emphasizing the role of exercise modality in promoting recovery and morphological changes in spinal cord injuries. Our findings will influence future strategies for rehabilitation exercises, restoring functional movement after spinal cord injury.

关键词： behavioral assessment motor function neural plasticity running wheel exercise spinal cord injury treadmill exercise voluntary exercise

基于颜色校正与改进的对比度增强的水下图像增强方法

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现代电子技术 2025年第1期48卷 40-46页

作者：刘明肖汉城云南民族大学电气信息工程学院云南昆明650500

针对水下介质分布不均匀引起的光吸收和散射导致图像颜色失真、对比度低、细节模糊,严重影响ORBSLAM2算法前端特征提取与匹配鲁棒性的问题,文中提出一种基于颜色校正与改进的自适应对比度增强的图像处理方法。首先,利用一种改进的颜色... 详细信息

针对水下介质分布不均匀引起的光吸收和散射导致图像颜色失真、对比度低、细节模糊,严重影响ORBSLAM2算法前端特征提取与匹配鲁棒性的问题,文中提出一种基于颜色校正与改进的自适应对比度增强的图像处理方法。首先,利用一种改进的颜色通道补偿和颜色通道拉伸方法去除色偏;其次,采用改进的自适应对比度增强方法提高图像的亮度与对比度;最后,将彩色校正图像与对比度增强图像在HSV空间中融合。此外,将提出的算法与一些其他算法进行主客观的评价,并将处理好的图片进行特征提取和匹配。结果表明,该算法处理的图片不仅在主客观评价上均优于对比算法,而且增加了特征点的匹配数量,为水下图像处理提供了借鉴。

关键词：水下视觉SLAM 水下图像增强自适应对比度增强颜色校正颜色补偿特征匹配

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Role of nutrition in diabetes mellitus and infections

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World Journal of Clinical Cases 2025年第3期13卷 1-8页

作者： Xue-Lu Yu Li-Yun Zhou xiao Huang Xin-Yue Li ming-Ke Wang Ji-Shun Yang Naval Medical Center of PLA Naval Medical UniversityShanghai 200052China

In this editorial,we have commented on the article that has been published in the recent issue of World Journal of Clinical *** authors have described a case of unilateral thyroid cyst and have opined that the acute onset of infection may be linked to diabetes mellitus(DM).We have focused on the role of nutrition in the association between DM and *** with DM are at a high risk of infection,which could also be attributed to nutrition-related *** interventions for patients with diabetes are mainly based on a low-calorie diet,which can be achieved by adhering to a low-carbohydrate ***,dietary fiber supplementation is recommended to maintain the diversity of the gut ***,high-quality protein can prevent the increased risk of infection due to *** of vitamins C,vitamins A,vitamins D,and folic acid improves blood sugar control and facilitates immune *** deficiencies augment the risk of infection,but the relationship with diabetes is mostly U-shaped and a good intake should be maintained.

关键词： Diabetes mellitus Infection Macronutrients Vitamins Minerals

Deciphering fungal metabolon coupling tandem inverse-electrondemand Diels-Alder reaction and semipinacol rearrangement for the biosynthesis of spiro polycyclic alkaloids

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Science China Chemistry 2025年第01期 288-296页

作者： Shuai Liu Wen-Qiang Xu Ying-Tong Di Man-Cheng Tang Ding-Kang Chen ming-ming Cao Yao-Wen Chang Hong-Yu Tang Chun-Mao Yuan Jun-Bo Yang Zhi-Li Zuo Han Guo Zi-Fei Xu Ying Zeng Yun-Dong Wu xiao-Jiang Hao Key Laboratory of Phytochemistry and Natural Medicines (Chinese Academy of Sciences) Kunming Institute of Botany Chinese Academy of Sciences University of Chinese Academy of Sciences Lab of Computational Chemistry and Drug Design State Key Laboratory of Chemical Oncogenomics Peking University Shenzhen Graduate School Shenzhen Bay Laboratory State Key Laboratory of Microbial Metabolism School of Life Sciences & Biotechnology Shanghai Jiao Tong University State Key Laboratory of Functions and Applications of Medicinal Plants Guizhou Medical University Molecular Biology Experimental Center Germplasm Bank of Wild Species in Southwest China Kunming Institute of Botany Chinese Academy of Sciences Yunnan Key Laboratory for Wild Plant Resources Kunming Institute of Botany Chinese Academy of Sciences Research Unit of Chemical Biology of Natural Anti-Virus Products Chinese Academy of Medical Sciences

In the intricate process of natural product biosynthesis, a metabolon can enhance metabolic flux by associating sequential enzymes. A fungal metabolon, comprising of flavin-dependent monooxygenase Spe F and P450 monooxygenase Spe G, is identified in the biosynthesis of spiro polycyclic alkaloids(+)-notoamide B and its diastereomer(+)-versicolamide B. Using notoamide E as a substance, Spe F/Spe G metabolon can control the stereoselectivity of its 2,3-epoxidation, followed by hydrogen atom ion at C-17 to generate reactive epoxide tau-m A with dienyl iminium unit. Subsequently,(+)-notoamide B and(+)-versicolamide B are produced via tandem nonenzymatic inverse-electron-demand Diels-Alder reaction and semipinacol rearrangement. This provides the first example of metabolon in the biosynthesis of spiro-prenylated indole alkaloids.

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Chondroitinase ABC combined with Schwann cell transplantation enhances restoration of neural connection and functional recovery following acute and chronic spinal cord injury

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Neural Regeneration Research 2025年第5期20卷 1467-1482页

作者： Wenrui Qu Xiangbing Wu Wei Wu Ying Wang Yan Sun Lingxiao Deng Melissa Walker Chen Chen Heqiao Dai Qi Han Ying Ding Yongzhi Xia George Smith Rui Li Nai-Kui Liu xiao-ming Xu Spinal Cord and Brain Injury Research Group Stark Neurosciences Research InstituteDepartment of Neurological SurgeryIndiana University School of MedicineIndianapolisINUSA Department of Hand Surgery the Second Hospital of Jilin UniversityChangchunJilin ProvinceChina Shriners Hospitals Pediatric Research Center Temple University School of MedicinePhiladelphiaPAUSA Department of Anatomy&Cell Biology Indiana University School of MedicineIndianapolisINUSA

Schwann cell transplantation is considered one of the most promising cell-based therapy to repair injured spinal cord due to its unique growth-promoting and myelin-forming properties.A the Food and Drug Administration-approved Phase I clinical trial has been conducted to evaluate the safety of transplanted human autologous Schwann cells to treat patients with spinal cord injury.A major challenge for Schwann cell transplantation is that grafted Schwann cells are confined within the lesion cavity,and they do not migrate into the host environment due to the inhibitory barrier formed by injury-induced glial scar,thus limiting axonal reentry into the host spinal *** we introduce a combinatorial strategy by suppressing the inhibitory extracellular environment with injection of lentivirus-mediated transfection of chondroitinase ABC gene at the rostral and caudal borders of the lesion site and simultaneously leveraging the repair capacity of transplanted Schwann cells in adult rats following a mid-thoracic contusive spinal cord *** report that when the glial scar was degraded by chondroitinase ABC at the rostral and caudal lesion borders,Schwann cells migrated for considerable distances in both rostral and caudal *** Schwann cell migration led to enhanced axonal regrowth,including the serotonergic and dopaminergic axons originating from supraspinal regions,and promoted recovery of locomotor and urinary bladder ***,the Schwann cell survival and axonal regrowth persisted up to 6 months after the injury,even when treatment was delayed for 3 months to mimic chronic spinal cord *** findings collectively show promising evidence for a combinatorial strategy with chondroitinase ABC and Schwann cells in promoting remodeling and recovery of function following spinal cord injury.

关键词： axonal regrowth bladder function chondroitinase ABC functional recovery glial scar lentivirus migration Schwann cell spinal cord injury transplantation

THREE-DIMENSIONAL NUMERICAL MODELLING OF THE WAVE-IN-DUCED RIP CURRENTS UNDER IRREGULAR BATHYMETRY

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Journal of Hydrodynamics 2012年第6期24卷 864-872页

作者： XIE ming-xiao School of Civil Engineering Tianjin University Tianjin Research Institute for Water Transport Engineering Ministry of Transport

A process-based 3-D hydrodynamic model is established to simulate the rip current structures under irregular bathymetry. The depth-varying wave-induced residual momentum, the surface rollers, the turbulent mixing and the wave-current interactions are considered. Experimental datasets are used to validate the model, and it is shown that the model can effectively describe the 3-D structures of the rip currents in both normal and oblique wave incident cases. The flow patterns of the rip currents see various characteristics for different incident wave directions. In the normal incident case, pairs of counter-rotating primary circulation cells are formed, and an offshore rip flow occurs in the embayment troughs. The peak seaward velocities occur at the top of the bed boundary layer, and the undertow is incorporated in addition to the rip currents. In the oblique incident case, the longshore currents are dominant, which result in a meandering flow along the depth contour, and the undertow is weaker compared to that in the normal incident condition.

关键词： rip currents irregular bathymetry 3-D numerical modelling

Blockage robust millimeter-wave networks

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Science China(Information Sciences) 2017年第8期60卷 77-79页

作者： Guang YANG ming xiao KTH Royal Institute of Technology

Millimeter-wave(mm Wave)technique(from around 24 GHz to 300 GHz)becomes a key enabler of high date rates for future mobile communications[1].In spite of many appealing benefits,mm Wave communications also encounter several critical challenges,i.e.,very weak capability in penetration,diffraction and high-order reflections,due to the short wavelength[2].That indicates,the transmission in mm Wave bands can be blocked easily if any obstacle,e.g.,human body or vehicle in motion,occurs on the propagation path.

关键词： Wave work in AP of as link TDMA Blockage robust millimeter-wave networks is or MBS MAC wave that

Study on implicit composite element method for seepage analysis in underground engineering

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Science China(Technological Sciences) 2015年第10期58卷 1617-1626页

作者： LI LingZi xiao ming State Key Laboratory of Water Resources and Hydropower Engineering Science Wuhan University Key Laboratory of Rock Mechanics in Hydraulic Structural Engineering Wuhan University Ministry of Education

Based on the basic principle of the finite element method, the implicit composite element method for numerical simulation of seepage in underground engineering is proposed. In the simulation, the faults and drainage holes are set implicitly in the model elements without adding additional elements. Elements containing fault or drainage-hole data are termed composite elements. Then, their information data in model could be obtained. By determining the osmotic transmission matrix of the composite elements, the permeability coefficient matrix is then obtained. The method was applied to the numerical simulation of the seepage field around the underground powerhouse of the Ganhe Pumping Station in Yunnan, China, using a compiled three-dimensional finite element method calculation program. The rock mass around the site includes two faults. The seepage field in the rock mass was analyzed at different stages of the engineering project. The results show that, before the excavation of the underground caverns, the rock mass seepage is affected by the faults and the groundwater permeated down along the tangential fault plane. After the excavation of the caverns during the operation period, the groundwater is basically drained away and the underground caverns are mostly above the groundwater level. Thus, the calculation results of the engineering example verify the implicit composite method for the simulation of faults and drainage holes. This method can well meet the calculation demands of practical engineering.

关键词： implicit composite element method numerical calculation seepage underground engineering faults drainage holes finite element method osmotic transmission matrix

Direct trajectory optimization based on a mapped Chebyshev pseudospectral method

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Chinese Journal of Aeronautics 2013年第2期26卷 401-412页

作者： Guo xiao Zhu ming School of Aeronautic Science and Engineering Beihang University

In view of generating optimal trajectories of Bolza problems, standard Chebyshev pseudospectral （PS） method makes the points＇ accumulation near the extremities and rarefaction of nodes close to the center of interval, which causes an ill-condition of differentiation matrix and an oscillation of the optimal solution. For improvement upon the difficulties, a mapped Chebyshev pseudospectral method is proposed. A conformal map is applied to Chebyshev points to move the points closer to equidistant nodes. Condition number and spectral radius of differentiation matrices from both methods are presented to show the improvement. Furthermore, the modification keeps the Chebyshev pseudospectral method＇s advantage, the spectral convergence rate. Based on three numerical examples, a comparison of the execution time, convergence and accuracy is presented among the standard Chebyshev pseudospectral method, other collocation methods and the proposed one. In one example, the error of results from mapped Chebyshev pseudospectral method is reduced to 5% of that from standard Chebyshev pseudospectral method.

关键词： Chebyshev approximation Conformal shift Interpolation Optimization Pseudospectral method Trajectory