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系统仿真学报 2008年第23期20卷 6538-6541页

作者：郑晓晖吴晓锋冷画屏海军兵种指挥学院

近程舰炮武器系统担负着舰艇末端防空反导任务。提出了一种评估反导射击效率的方法,该方法选取了单目标毁伤概率、毁伤目标数学期望、服务概率作为射击效率指标。在确定舰炮武器系统有效射击区域的基础上,分析了反导可射击条件,研究了... 详细信息

近程舰炮武器系统担负着舰艇末端防空反导任务。提出了一种评估反导射击效率的方法,该方法选取了单目标毁伤概率、毁伤目标数学期望、服务概率作为射击效率指标。在确定舰炮武器系统有效射击区域的基础上,分析了反导可射击条件,研究了对单目标沿其航路射击的可射击时间、点射次数、受到各次点射的概率,利用经验公式得到单目标毁伤概率。然后,研究了多座舰炮对群目标射击时毁伤目标数学期望、服务概率两项评估指标的计算方法。实例计算分析表明该方法有效可行。

关键词：舰炮反导毁伤概率毁伤目标数学期望服务概率

基于MCSP的舰艇训练模拟系统可靠性分配研究

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系统仿真学报 2008年第24期20卷 6821-6824,6829页

作者：郑晓晖吴晓锋冷画屏海军兵种指挥学院广州510430

可靠性分配是舰艇训练模拟系统可靠性工程的重要环节。针对系统的使命任务,规划了系统的寿命剖面和任务剖面,建立了系统的任务可靠性模型。按照规定的任务可靠性指标,采用多因子系数专家评分方法将全系统的任务可靠性指标分配到各分系... 详细信息

可靠性分配是舰艇训练模拟系统可靠性工程的重要环节。针对系统的使命任务,规划了系统的寿命剖面和任务剖面,建立了系统的任务可靠性模型。按照规定的任务可靠性指标,采用多因子系数专家评分方法将全系统的任务可靠性指标分配到各分系统或设备层面,得到初步分配结果。然后,依据任务可靠性模型预计系统的任务成功概率(MCSP),比照系统规定的任务可靠性指标,进行迭代修正计算,最终得到了满足规定要求的可靠性分配优化结果。

关键词：舰艇训练模拟系统可靠性分配任务剖面可靠性模型任务成功概率(MCSP)

Plasmonic tandem heterojunctions enable high-efficiency charge transfer for broad spectrum photocatalytic hydrogen production

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Journal of Energy Chemistry 2025年第1期100卷 710-720页

作者： Wenxuan Chen Xiu-Qing Qiao Guo hui Bojing Sun Dongfang Hou Meidi Wang Xueqian wu Tao wu Dong-Sheng Li College of Materials and Chemical Engineering Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials China Three Gorges University Hubei Three Gorges Laboratory College of Chemistry and Materials Science and Guangdong Provincial Key Laboratory of Supramolecular Coordination Chemistry Jinan University

Rational engineering of semiconductor photocatalysts for efficient hydrogen production is of great significance but still challenging,primarily due to the limitations in charge transfer ***,a fascinating plasmonic tandem heterojunction with the hc-CdS/Mo2C@C heterostructure is aimfully prepared for effectively promoting the charge separation kinetics of the CdS photocatalyst via the synergistic strategy of phase junction,Schottky junction,and photothermal *** difference in atomic configuration between cubic-CdS （c-CdS） and hexagonal-CdS （h-CdS） leads to effective charge separation through a typical Ⅱ charge transfer mechanism,and plasmonic Schottky junction further extracts the electrons in the hc-CdS phase junction to realize gradient charge ***,the photothermal effect of Mo2C@C helps to expand the light absorption,accelerate charge transfer kinetics,and reduce the hydrogen evolution energy *** carbon layer provides a fast channel for charge transfer and protects the photocatalyst from *** a result,the optimized hc-CMC photocatalyst exhibits a significantly high photocatalytic H2production activity of 28.63 mmol/g/h and apparent quantum efficiency of 61.8%,surpassing most of the reported *** study provides a feasible strategy to enhance the charge transfer kinetics and photocatalytic activity of CdS by constructing plasmonic tandem heterogeneous junctions.

关键词： Heterojunctions LSPR Photocatalyst Phase junction Schottky junction Photothermal effect

不同镇痛方法对膝关节置换术患者术后疼痛及膝关节功能恢复的影响

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中国医院药学杂志 2017年第6期37卷 530-532页

作者：陈小妹林惠武厦门大学附属第一医院麻醉科福建厦门361006 厦门大学附属第一医院药剂科福建厦门361006

目的:比较伤口浸润麻醉和股神经阻滞(FNB)2种镇痛方法对膝关节置换术(TKA)患者术后疼痛及膝关节功能恢复的影响。方法:将72名患者通过计算机产生随机数来进行随机化随机分为2组(伤口浸润麻醉组和FNB组),每组36人。FNB组接受连续的股神... 详细信息

目的:比较伤口浸润麻醉和股神经阻滞(FNB)2种镇痛方法对膝关节置换术(TKA)患者术后疼痛及膝关节功能恢复的影响。方法:将72名患者通过计算机产生随机数来进行随机化随机分为2组(伤口浸润麻醉组和FNB组),每组36人。FNB组接受连续的股神经阻滞治疗,伤口浸润麻醉组注射脂质体布比卡因。从VAS疼痛评分、转换成氢可酮当量的阿片总量、术后使用的阿片制剂的数量、术后2周膝关节活动度和初次下床活动时间等方面观测2种镇痛方法的疗效。结果:相比较而言FNB组需要更高的麻醉剂量(P<0.001)。在术后的首5 d内,相比较于伤口浸润麻醉组的平均视觉模拟疼痛分数(1.74),FNB组更高(2.01)。在不引起剧烈疼痛的情况下,伤口浸润麻醉组术后膝关节弯曲角度明显高于FNB组(P<0.05)。伤口浸润麻醉组患者初次下床活动时间明显大于FNB组(P<0.05)。结论:在术后镇痛和及膝关节功能恢复方面,长效脂质体布比卡因浸润技术优于连续股神经阻滞治疗,并且麻醉用药更少。

关键词：镇痛麻醉膝关节置换术股神经阻滞

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茶树茶氨酸的代谢及其育种研究进展

园艺学报 2016年第9期43卷 1791-1802页

作者：方开星姜晓辉吴华玲广东省农业科学院茶叶研究所广东省茶树资源创新利用重点实验室广州510640

茶氨酸是茶树特征性生化物质,不仅能调节茶树氮代谢及转运,影响茶叶品质,同时对人体还具有镇静、安神等保健功能。茶氨酸含量是数量性状,在茶树体内合成不仅受基因调控且易受环境影响。对茶氨酸的分布及变化规律、代谢途径及相关基因、... 详细信息

茶氨酸是茶树特征性生化物质,不仅能调节茶树氮代谢及转运,影响茶叶品质,同时对人体还具有镇静、安神等保健功能。茶氨酸含量是数量性状,在茶树体内合成不仅受基因调控且易受环境影响。对茶氨酸的分布及变化规律、代谢途径及相关基因、外界影响因子及高茶氨酸品种选育等研究现状进行了综述,旨在为高茶氨酸茶树种质筛选及其高含量形成的机制研究提供参考。

关键词：茶树茶氨酸育种基因

Observation of acoustic hybrid topological phases induced by the p-d orbital interactions

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Science China(Physics,Mechanics & Astronomy) 2025年第1期Mechanics & Astronomy) .卷 132-139页

作者： xiao Xiang Feng Gao Yu-Gui Peng Peng wu Zong-Lin Li Xue-Feng Zhu School of Physics and Innovation Institute Huazhong University of Science and Technology

In spinless systems,growing attention has recently been attracted to synthetic gauge fields,which redefine the fundamental crystal symmetries by utilizing the projective algebraic ***,synthetic gauge fields have been commonly investigated in single orbital systems,and explorations on hybrid orbitals remain elusive in ***,we report the experimental observation of hybrid topological phases induced by hybrid synthetic gauge flux,which is formed by the interaction between p and d orbitals embedded in acoustic *** breaking the translation symmetries of Lxand/or Ly,we unambiguously demonstrate the first-order M?bius edge states and higher-order corner *** work establishes a platform for seeking exotic topological phases induced by hybrid-orbitals interactions and initializing the framework of hybrid-orbitalsrelated topological *** applications can be anticipated in scenarios such as high-quality sensing and robust wave trapping due to the stepwise energy distribution of the hybrid topological phase.

关键词： topological insulator synthetic gauge field projective symmetry corner states

Tuning the interfacial reaction environment via pH-dependent and induced ions to understand C–N bonds coupling performance in NO3- integrated CO2 reduction to carbon and nitrogen compounds over dual Cu-based N-doped carbon catalyst

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Journal of Energy Chemistry 2025年第1期100卷 273-285页

作者： Tianhang Zhou Chen Shen Zhenghao wu Xingying Lan Yi xiao College of Carbon Neutrality Future Technology State Key Laboratory of Heavy Oil Processing China University of Petroleum (Beijing) Institute of Materials Science TU Darmstadt Department of Chemistry Xi'an Jiaotong-Liverpool University Department of Mechanical and Mechatronics Engineering and Waterloo Institute of Nanotechnology University of Waterloo Waterloo

Dual atomic catalysts （DAC）,particularly copper （Cu2）-based nitrogen （N） doped graphene,show great potential to effectively convert CO2and nitrate （NO3-） into important industrial chemicals such as ethylene,glycol,acetamide,and urea through an efficient catalytical process that involves C–C and C–N ***,the origin of the coupling activity remained unclear,which substantially hinders the rational design of Cu-based catalysts for the N-integrated CO2reduction reaction （CO2RR）.To address this challenge,this work performed advanced density functional theory calculations incorporating explicit solvation based on a Cu2-based N-doped carbon (Cu2N6C10) catalyst for *** calculations are aimed to gain insight into the reaction mechanisms for the synthesis of ethylene,acetamide,and urea via coupling in the interfacial reaction *** to the sluggishness of CO2,the formation of a solvation electric layer by anions （F-,Cl-,Br-,and I-） and cations (Na+,Mg2+,K+,and Ca2+) leads to electron transfer towards the Cu *** process significantly accelerates the reduction of *** results reveal that*CO intermediates play a pivotal role in N-integrated ***,the Cu2-based N-doped carbon catalyst examined in this study has demonstrated the most potential for C–N coupling to *** findings reveal that through the process of a condensation reaction between*CO and NH2OH for urea synthesis,*NO3-is reduced to*NH3,and*CO2to*CCO at dual Cu atom *** dual-site reduction facilitates the synthesis of acetamide through a nucleophilic reaction between NH3and the ketene ***,we found that the I-and Mg2+ions,influenced by pH,were highly effective for acetamide and ammonia synthesis,except when F-and Ca2+were ***,the mechanisms of C–N bond formation were investigated via ab-initio molecular dynamics simulations,and we found that adjusting the micro-environment can change the dominant side reaction,shift

关键词： pH-dependent micro-environments C–N coupling Dual Cu-based nitrogen carbon catalysts Explicit solvation model Ion stabilizer AIMD

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卵母细胞减数分裂转变过程的调控机制

生殖与避孕 2009年第11期29卷 741-745页

作者：吴晓慧李卫平狄文上海交通大学医学院附属仁济医院妇产科上海200001

卵母细胞的成熟包括第一次减数分裂恢复、第一次减数分裂向第二次减数分裂转变、第二次减数分裂中期阻滞等过程,其中第一次减数分裂向第二次减数分裂的转变是卵母细胞成熟的关键步骤之一,但其机制目前尚不清楚。丝裂原激活蛋白激酶、成... 详细信息

卵母细胞的成熟包括第一次减数分裂恢复、第一次减数分裂向第二次减数分裂转变、第二次减数分裂中期阻滞等过程,其中第一次减数分裂向第二次减数分裂的转变是卵母细胞成熟的关键步骤之一,但其机制目前尚不清楚。丝裂原激活蛋白激酶、成熟促进因子、内源性减数分裂抑制因子、Separase/Securin蛋白、Aurora激酶等多种已知或未知的蛋白可通过泛素-蛋白酶体通路、磷脂酰肌醇通路、受体酪氨酸激酶-Ras蛋白通路、环磷酸腺苷通路等多个信号通路调控卵母细胞的成熟。通过研究这些通路中关键蛋白间的相互作用有助于进一步探索卵母细胞成熟的调控机制。

关键词：减数分裂第一次减数分裂中期第二次减数分裂中期信号转导通路

Zwitterionic hyaluronic acid derivatives for co-delivery of both chemotherapeutic and nucleic acid drugs in breast cancer treatment

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Nano Research 2025年第1期18卷 607-617页

作者： Ruo-Lin Jiang hui-Na Liu Yu-Fan Yang Zhi-Cheng Zhang Qi Dai xiao-Yan Bao Lin-Jie wu Ya-Xin Qin Xin Tan xiao-Yan Sun Xu-Fang Ying Zhi-Qing Ben Min Han Institute of Pharmaceutics College of Pharmaceutical SciencesZhejiang UniversityHangzhou 310058China Department of Radiation Oncology Key Laboratory of Cancer Prevention and InterventionThe Second Affiliated HospitalCollege of MedicineZhejiang UniversityHangzhou 310058China Hangzhou Institute of Innovative Medicine Zhejiang UniversityHangzhou 310058China Jinhua Institute of Zhejiang University Jinhua 321299China National Key Laboratory of Advanced Drug Delivery and Release Systems Zhejiang UniversityHangzhou 310058China Polytechnic institute Zhejiang UniversityHangzhou 310015China

Traditionally,hyaluronic acid has been widely used for drug delivery,but the current application bottleneck is that hyaluronic acid is hydrophilic and electronegative,which makes it difficult to carry hydrophobic drugs and small interfering RNA(siRNA)with the same *** on previous studies,we designed and synthesized hyaluronic acid nanocarriers HA-spermine/N,N,N-trimethylcystamine/DOX-TPP(HSTD)for loading siRNA to overcome the problem of siRNA release caused by strong electrostatic ***,N,N,Ntrimethylcystamine in the carrier can be degraded by intracellular glutathione to completely and rapidly release siRNA,thus promoting ***,when codelivered with the chemotherapy drug doxorubicin(DOX),this novel nanocarrier showed promising synergy in inhibiting tumor growth.

关键词： zwitterionic hyaluronic acid N N N-trimethylcystamine small interfering RNA(siRNA) doxorubicin