检索结果-南通市图书馆

Investigating the relationship between intracranial atherosclerotic plaque remodelling and diabetes using high-resolution vessel wall imaging

引用

World Journal of Diabetes 2024年第1期15卷 72-80页

作者： Yong-Qian Mo Hai-yu Luo han-Wen Zhang yu-Feng Liu Kan Deng xiao-Lei Liu Biao Huang Fan Lin Department of Radiology Peking University Shenzhen HospitalShenzhen 518000Guangdong ProvinceChina Department of Ultrasound Peking University Shenzhen HospitalShenzhen 518000Guangdong ProvinceChina The Second School of Clinical Medicine Southern Medical UniversityGuangzhou 510282Guangdong ProvinceChina Department of Radiology The First Affiliated Hospital of Shenzhen UniversityHealth Science CenterShenzhen Second People’s HospitalShenzhen 518036Guangdong ProvinceChina Research Department Philips HealthcareGuangzhou 518000Guangdong ProvinceChina Department of Radiology Guangdong Provincial People’s HospitalGuangdong Academy of Medical SciencesGuangzhou 510000Guangdong ProvinceChina

BACKGROUND Intracranial atherosclerosis,a leading cause of stroke,involves arterial plaque *** study explores the link between plaque remodelling patterns and diabetes using high-resolution vessel wall imaging(HR-VWI).AIM To investigate the factors of intracranial atherosclerotic remodelling patterns and the relationship between intracranial atherosclerotic remodelling and diabetes mellitus using *** Ninety-four patients diagnosed with middle cerebral artery or basilar artery INTRODUCTION Intracranial atherosclerotic disease is one of the main causes of ischaemic stroke in the world,accounting for approx-imately 10%of transient ischaemic attacks and 30%-50%of ischaemic strokes[1].It is the most common factor among Asian people[2].The adaptive changes in the structure and function of blood vessels that can adapt to changes in the internal and external environment are called vascular remodelling,which is a common and important pathological mechanism in atherosclerotic diseases,and the remodelling mode of atherosclerotic plaques is closely related to the occurrence of *** remodelling(PR)is an outwards compensatory remodelling where the arterial wall grows outwards in an attempt to maintain a constant lumen *** a long time,it was believed that the degree of stenosis can accurately reflect the risk of ischaemic stroke[3-5].Previous studies have revealed that lesions without significant luminal stenosis can also lead to acute events[6,7],as summarized in a recent meta-analysis study in which approximately 50%of acute/subacute ischaemic events were due to this type of lesion[6].Research[8,9]has pointed out that the PR of plaques is more dangerous and more likely to cause acute ischaemic *** studies[10-13]have found that there are specific vascular remodelling phenomena in the coronary and carotid arteries of diabetic ***,due to the deep location and small lumen of intracranial arteries and limitations of i

关键词： High-resolution vessel wall imaging Intracranial atherosclerosis Vascular remodelling Magnetic resonance imaging

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Layered(C_(5)H_(6)ON)_(2)[Sb_(2)O(C_(2)O_(4))_(3)]with a large birefringence derived from the uniform arrangement of π-conjugated units

引用

Chinese Journal of Structural Chemistry 2024年第6期43卷 50-55页

作者： Dong-Xue Jiao Hui-Li Zhang Chao He Si-yu Chen Ke Wang xiao-han Zhang Li Wei Qi Wei College of Chemistry and Chemical Engineering Qingdao UniversityShandong266071PR China College of Science Hebei University of Science and TechnologyShijiazhuangHebei050018PR China

An organic-inorganic hybrid antimony(Ⅲ)oxalate(C_(5)H_(6)ON)_(2)[Sb_(2)O(C_(2)O_(4))_(3)]has been successfully obtained by simultaneous combination of a-conjugated 4-hydroxypyridine and(C_(2)O_(4))^(2-)group with stereochemical active Sb(Ⅲ)*** compound features a layered structure,and the equatorial planes of SbO6 units,π-conjugated(C_(2)O_(4))^(2-)and(C5H6ON)+groups are closer to a planar arrangement,representing strong structural anisotropy that favors a large *** expected,(C_(5)H_(6)ON)_(2)[Sb_(2)O(C_(2)O_(4))_(3)]exhibits a large birefringence of 0.279 at 546 *** and theoretical analyses indicate that the combination of multipleπ-conjugated units is a feasible approach for designing and exploring new superior birefringent materials.

关键词： Organicπ-conjugated unit Birefringence Stereochemically active lone pair Layered structure

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modifying effects and mechanisms of superfine stainless wires on microstructures and mechanical properties of ultra-high performance seawater sea-sand concrete

引用

Science China Technological Sciences 2024年第10期67卷 3205-3220页

作者： yu Feng DONG SuFen ASHOUR Ashraf DING SiQi han BaoGuo School of Infrastructure Engineering Dalian University of Technology Faculty of Engineering & Informatics University of Bradford Department of Civil and Environmental Engineering The Hong Kong Polytechnic University

Ultra-high-performance seawater sea-sand concrete（UHPSSC） presents a prospective solution to address the natural resource shortage in marine infrastructure construction. To eliminate the corrosion risk of steel fibers and broaden the applicability of UHPSSC, this study investigates the mechanical properties and free chloride ion content as well as microstructures of UHPSSC reinforced with superfine stainless wires（SSWs） under natural curing. The results indicate that 1.5% SSWs can remarkably improve the flexural strength and toughness of UHPSSC by 127% and 1724%, respectively, and mitigate the long-term strength degradation of UHPSSC. The strong interfacial bond between SSW and UHPSSC improves the compactness of UHPSSC, thus reducing the growth space for Ca（OH）2crystals and swelling hydration products generated by sulfate and magnesium ions. This can be supported by the observed reduction in the Ca/Si ratio of C–S–H gels, CH crystal orientation index, and ***, through mechanisms such as pull-out, rupture, overlapping network, and internal anchor interface, SSWs effectively prevent microcrack growth and propagation, transforming single long-connected microcracks into multiple-emission microcracks centered on SSW. Additionally, the free chloride ion content of the composites at 28 and 180 d meets the ACI 318-19 standard requirements for concrete exposed to seawater. This compliance is attributed to the chloride immobilization facilitated by Friedel's salt and C–S–H gels within the interfaces around SSWs and sea-sand. Consequently, SSWs-reinforced UHPSSC exhibits considerable potential for applications in sustainable marine infrastructures, demanding long-term mechanical properties and high durability.

关键词： ultra-high performance seawater sea-sand concrete superfine stainless wire mechanical properties chloride ion content microstructure

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Recent advances in FeCl_(3)-photocatalyzed organic reactions via hydrogen-atom transfer

引用

Chinese Chemical Letters 2024年第9期35卷 32-40页

作者： xiao-Ya yuan Cong-Cong Wang Bing yu Green Catalysis Center College of ChemistryZhengzhou UniversityZhengzhou 450001China National Engineering Research Center of Low-Carbon Processing and Utilization of Forest Biomass Nanjing Forestry UniversityNanjing 210037China

In recent years,FeCl_(3)-photocatalyzed direct C–H/Si–H bond functionalization reactions have attracted huge *** those transformations,chlorine radical(Cl·)could be generated from FeCl_(3)via a ligandto-metal charge transfer(LMCT)/homolysis process under light *** resulting chlorine radical subsequently acts as a hydrogen atom transfer(HAT)agent to abstract the hydrogen atom of aliphatic C–H,O–H,or Si–H bonds to give the corresponding C/Si/O-centered radicals for various organic *** this review,we summarized the recent advances in the application of FeCl_(3)as a HAT photocatalyst for the C/Si–H functionalization to construct C–C,C–N,C–Si,C–S,C–B,and C-P bonds.

关键词： FeCl_(3) Photocatalysis Ligand-to-metal charge transfer Hydrogen atom transfer Chlorine radical

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Molecular docking-aided AIEgen design: concept, synthesis and applications

引用

Science China Chemistry 2024年第8期67卷 2614-2628页

作者： Jian-Qing Zhang xiao-yu Xu Fu-Sheng Liu Shu-Qiang Cao yu-Xin Gui Yi-Wen Su xiao-yu He Ji-yuan Liang You-Quan Zou Department of Radiation and Medical Oncology Zhongnan Hospital of Wuhan UniversitySchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Key Laboratory of Combinatorial Biosynthesis and Drug Discovery Ministry of EducationWuhan UniversityWuhan 430071China Tai Kang Center for Life and Medical Sciences Wuhan UniversityWuhan 430071China Department of Hepatobiliary Pancreatic SurgeryZhongnan Hospital of Wuhan UniversityWuhan 430071China

Aggregate-induced emission luminogens(AIEgens) have been widely used in biological imaging, chemical sensing, and disease treatments. The rational design and construction of AIEgens have received considerable research interests during the last few years. Herein, molecular docking-aided AIEgen design has been reasonably proposed and AIEgen TBQZY with excellent ~1O_(2) generation ability has been synthesized. The newly developed TBQZY could efficiently kill S. epidermidis and methicillinresistant S. epidermidis(MRSE) by tightly binding to bacteria and triggering the accumulation of ~1O_(2) in bacteria. TBQZY specifically regulated the immune system and polarized macrophages from M1 to M2 to accelerate the elimination of biofilm in vivo. In addition, healing acceleration was observed in chronic wounds treated with TBQZY, and side effects were ***, TBQZY had extraordinary potential for combating drug-resistant bacteria in the clinical setting. This research not only provided new concepts for the design of AIEgens, but also shed some lights on the discovery of drugs against drug-resistant bacteria.

关键词： AIEgen molecular docking drug-resistant bacteria biofilm chronic wounds healing

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Publication trends of Leber congenital amaurosis researches:a bibliometric study during 2002-2022

引用

International Journal of Ophthalmology(English edition) 2024年第8期17卷 1501-1509页

作者： xiao-Xu Huang Yi-Min Wang Min-yue Xie Yi-Qing Sun xiao-Huan Zhao yu-Hong Chen Jie-Qiong Chen Si-Yang han Min-Wen Zhou xiao-Dong Sun Department of Ophthalmology Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China National Clinical Research Center for Eye Disease Shanghai 200080China Shanghai Key Laboratory of Ocular Fundus Diseases Shanghai 200080China Shanghai Engineering Center for Visual Science and Photomedicine Shanghai 200080China Department of Ophthalmology Zhongshan HospitalFudan UniversityShanghai 200030China Beijing Tongren Hospital Capital Medical UniversityBeijing 100054China Eberly College of Science Penn State UniversityUniversity Park 16802-1503United States

AIM:To analyze the changes in scientific output relating to Leber congenital amaurosis(LCA)and forecast the study trends in this ***:All of the publications in the field of LCA from 2002 to 2022 were collected from Web of Science(WOS)*** analyzed the quantity(number of publications),quality(citation and H-index)and development trends(relative research interest,RRI)of published LCA research over the last two ***,VOSviewer software was applied to define the co-occurrence network of keywords in this ***:A total of 2158 publications were ultimately *** found that the focus on LCA kept rising and peaked in 2015 and 2018,which is consistent with the development trend of gene *** USA has contributed most to this field with 1162 publications,56674 citations and the highest H-index value(116).The keywords analysis was divided into five clusters to show the hotspots in the field of LCA,namely mechanism-related,genotype-related,local phenotype-related,system phenotype-related,and *** also identified gene therapy and antiretinal degeneration therapy as a major focus in recent ***:Our study illustrates historical research process and future development trends in LCA *** may help to guide the orientation for further clinical diagnosis,treatment and scientific research.

关键词： VOSviewer bibliometrics Leber congenital amaurosis gene therapy hotpots

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Escape probability for isotropic emitters near Kerr black hole with astrometric

引用

Communications in Theoretical Physics 2024年第5期76卷 128-133页

作者： yu-Xuan han Qing-Hua Zhu Qing-Guo Huang CAS Key Laboratory of Theoretical Physics Institute of Theoretical PhysicsChinese Academy of SciencesBeijing 100190China School of Physical Sciences University of Chinese Academy of SciencesNo.19A Yuquan RoadBeijing 100049China Department of Physics Chongqing UniversityChongqing 401331China School of Fundamental Physics and Mathematical Sciences hangzhou Institute for Advanced Study UCASHangzhou 310024China

The paper investigates the escape probability for isotropic emitters near a Kerr black *** propose a new approach to obtain the escape probability in a general manner,going beyond previous case-by-case *** approach is based on studies of the black hole shadow with astrometric observable and can be applied to emitters with an arbitrary 4-velocities and locations,even to the emitters outside of the equatorial *** also consider representative examples illustrating how escape probabilities vary with distance,velocity,and inclination ***,this new approach provides an effective method for studying escape probabilities near Kerr black holes.

关键词： Kerr black hole photon escape probability isotropic emitters

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

The variation of microbiological characteristics in surface waters during persistent precipitation

引用

Frontiers of Environmental Science & Engineering 2024年第9期18卷 67-78页

作者： Xinyan xiao Chenlan Chen Haoran Li Lihua Li Xin yu College of the Environment&Ecology Xiamen UniversityXiamen 361102China Fujian Key Laboratory of Coastal Pollution Prevention and Control Xiamen UniversityXiamen 361102China

Climate change leads to an increase in both the frequency and intensity of extreme *** runoff generated by extreme precipitation has a significant impact on ***,the impact of persistent precipitation on surface water quality is easy to neglect,due to its prolonged duration and lower-intensity *** study established eight sampling points within selected surface waters to observe the variation of microbial characteristics in a typical persistence precipitation *** primary difference between Furong Lake(FL)and Chengqian Reservoir(CR)was:the concentrations of dissolved organic carbon(DOC)were 21.3±0.7 and 8.3±1.5 mg/L in FL and CR,*** concentrations of R2A culturable bacteria and coliforms were 10^(4.57)and 10^(1.58)colony-forming units(CFU)/mL in FL,and were 10^(5.46)and 10^(2.64)CFU/mL in CR,*** precipitation,the maximum increase concentrations of R2A,NA culturable bacteria,and coliforms were 10^(0.75),10^(1.30),and 10^(2.27)CFU/mL in FL,***,microbial concentration and rainfall did not increase simultaneously,and a delay phenomenon was observed in the increasing microbial *** analyzing the concentration change trends and correlation of various water quality indicators during persistent precipitation,the significant correlation between the DOC concentration and the changes in the dominant species of microbial community structure was found in this study(p<0.05).For example,as the DOC concentration declined,the abundance of hgcl_clade and CL500-29_marine_group ***,although persistent precipitation might not obviously alter the water quality visibly,it could still pose potential microbial risks.

关键词： Rainfall Dissolved organic carbon Culturable bacteria Water quality Microbial community structure Climate change

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Increased Expression of Serum Monocyte Chemoattractant Protein-1,Chemokine(C-C motif)Ligand 3,and Interleukins in Patients With Vitiligo

引用

International Journal of Dermatology and Venereology 2024年第1期7卷 40-43页

作者： xiao-Ling Zhao Ya-Lan Li Zi-han Li xiao-Chong Zhang Li-Hui An yu-Jiao Sun Deng-Xiang Liu Fang Cheng Cancer Laboratory Xingtai People’s HospitalXingtaiHebei 054001China Endocrine Department Xingtai People’s HospitalXingtaiHebei 130500China Dermatological Department Xingtai People’s HospitalXingtaiHebei 054001China

Objective:Vitiligo is a chronic,acquired depigmentation of the skin,which can be divided into active and stable *** stable and active stages are not immutable and often *** of internal markers would help to diagnose the active stage of vitiligo,and the purpose of this study was to find potential active markers in the progression of ***:We compared 30 healthy controls to 60 patients with vitiligo(30 with active disease and 30 with stable disease)regarding the expression of serum monocyte chemoattractant protein(MCP)-1,chemokine(C-C motif)ligand(CCL)3,CCL5,CCL21,interleukin(IL)-6,and *** were collected from May 2017 to December *** detection was carried out by enzyme-linked immunosorbent *** difference between groups was compared by Kruskal-Wallis H test and Mann-Whitney U ***:We found that the serum levels of MCP-1,CCL3,IL-6,and IL-17 were significantly higher in patients with vitiligo than in healthy controls(Phan in those with stable vitiligo(P<0.01).After 3months of treatment,the serum IL-17 level of patients with active vitiligo was not significantly different from that before treatment(P=0.526);after 6months of treatment,however,the serum IL-17 level had significantly decreased(P<0.01).Conclusion:These findings suggest that the serum IL-17 level can be used as a marker of vitiligo disease activity giving it certain guiding significance for clinical treatment.

关键词： clinical marker serum cytokines vitiligo

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Multiscale spatiotemporal meteorological drought prediction:A deep learning approach

引用

Advances in Climate Change Research 2024年第2期15卷 211-221页

作者： Jia-Li ZhanG xiao-Meng HUANG yu-Ze SUN Department of Earth System Science Ministry of Education Key Laboratory for Earth System ModellingInstitute for Global Change StudiesTsinghua UniversityBeijing 100084China

Reliable monitoring and thorough spatiotemporal prediction of meteorological drought are crucial for early warning and decision-making regarding drought-related *** utilisation of multiscale methods is effective for a comprehensive evaluation of drought occurrence and progression,given the complex nature of meteorological ***,the nonlinear spatiotemporal features of meteorological droughts,influenced by various climatological,physical and environmental factors,pose significant challenges to integrated prediction that considers multiple indicators and time *** address these constraints,we introduce an innovative deep learning framework based on the shifted window transformer,designed for executing spatiotemporal prediction of meteorological drought across multiple *** formulate four prediction indicators using the standardized precipitation index and the standard precipitation evaporation index as core methods for drought definition using the ERA5 reanalysis *** indicators span time scales of approximately 30 d and one ***-term indicators capture more anomalous variations,whereas long-term indicators attain comparatively higher accuracy in predicting future *** focus on the East Asian region,notable for its diverse climate conditions and intricate terrains,to validate the model's efficacy in addressing the complexities of nonlinear spatiotemporal *** model's performance is evaluated from diverse spatiotemporal viewpoints,and practical application values are analysed by representative drought *** results substantiate the effectiveness of our proposed model in providing accurate multiscale predictions and capturing the spatiotemporal evolution characteristics of *** of the four drought indicators accurately delineates specific facets of the meteorological drought ***,three representative drought events,namely flash drought,sustained drought and severe drought,

关键词： Meteorological drought Spatiotemporal prediction Multiscale Swim transformer Deep learning

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：