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A CASE STUDY ON CONCENTRATION AND DECENTRALIZATION:BEHAVIOR AND DYN AMIC MECHANISM OF SPATIAL EVOLUTION IN METROPOLITAN AREA,NANJING,CHINA

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Chinese Geographical Science 2002年第3期12卷 212-217页

作者： ZHU xi-gang,zhang Jing-xiang,CHEN Hu (Department of Urban and Resources Sciences,Nanjing University,Nanjin g 210093,P.R.China,) Department of Urban and Resources Sciences Nanjing University Nanjing P. R. China

In rapid socio-economic developme nt,the process of concentration and dispersal of various elements tends to be more dramatic,tremendously in fluencing the shaping and transform ation of the space in metropolitan *** of spatial concentration and decent ralization has thus become a basic me thod in examining metropolitan spatial *** this research,three elements were selected as the essential indicato rs of the process:demographic density distribu-tion,employment density distribut ion and business office *** of these elements in Nanji ng City was exam-ined *** Nanjing City c ould be regarded as a representative of metropolitan areas in China,its s ituation large-ly suggestes the general characteristics in similar areas of *** based on the investigation of Nanji ng City,four general implications were highligh ***,metropolitan areas inChina are in a violentprocess and shift of spatialconcentra-tion and ***,from now to at least the near future,c oncentration will continue to be the central ***,the landscape of metrop olitan areas basically exhibits a dual structure *** gap in en vironmental and ecological qualities among different districts will continue for a l ong ***,Central Business District(CBD)is playing an important role in helpi ng to convert the traditionally single-centered city structure into a polycentric one.

关键词： concentration decentralization dynamic mechanism nanjing metropolis

Dynamic observation of bone marrow suppression and chromosomal aberrations in patients with acute colchicine poisoning

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World Journal of Emergency Medicine 2022年第2期13卷 130-134页

作者： Yan-qing Liu xiao-xia Lu Kai-xun Hu xiao-bo Peng Yun Jiang Li-mei Han Zhi-qiang Ma Ming-fei Peng Kun Wan xi-gang zhang Ze-wu Qiu Poisoning Treatment Department Department of Hematologythe Fifth Medical Center of Chinese PLA General HospitalBeijing 100039China Academy of Military Medical Sciences Academy of Military SciencesBeijing 100850China

Colchicine is a neutral lipophilic tricyclic alkaloid toxic to human cells containing tubulin,[1-2]and primarily stops the proliferation of active cells in the mitotic metaphase,such as intestinal mucosal cells and hematopoietic *** is widely used in treating gout and familial Mediterranean fever,while it is also used in establishing animal and plant experimental model.[3]In the recent study,treatment of patients affected by coronavirus disease 2019(COVID-19)with colchicine may prove a viable path.[4]The course of colchicine poisoning can be divided into three stages,[5]and most of the patients died in the second stage(2-7 d,the multiple organ injury stage).The cause of death was heart failure[6]and bone marrow hematopoietic failure in the terminal phase.[7]Hematopoiesis is a classic sign of colchicine *** cases of colchicine poisoning have been comprehensively reported,and the target organs included heart,digestive tract,muscle,lung,kidney,hematopoietic system,etc.[8-11]This study aimed to investigate the injury of bone marrow hematopoietic system after colchicine poisoning and evaluate the therapeutic effect of bone marrow hematopoietic stimulation drugs.

关键词： establishing neutral alkaloid

Twelve family members with tetramine poisoning after consumption of vegetables grown in polluted soils

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World Journal of Emergency Medicine 2023年第3期14卷 250-252页

作者： Yan-qing Liu xiao-xia Lu Chun-yan Wang Ming-fei Peng xiao-bo Peng Yun Jiang Le-xin Zheng Dan-dan Yuan xi-gang zhang Ze-wu Qiu Poisoning Treatment Department Senior Department of Hepatologythe Fifth Medical Center of PLA General HospitalBeijing 100071China

The main toxic component of tetramine is tetramethylenedisulfotetramine(TETS).It is a sulfonamide derivative without special antidote,tasteless and tasteless,with high toxicity and high mortality.[1]It was first discovered by a German scientist Hagen in *** its use has been banned worldwide due to its high toxicity and mortality rate,it is still available in certain countries and has led to cases of intentional and unintentional *** blocksγ-neurons,leading to dizziness,fatigue,nausea,vomiting,convulsions,and other symptoms.[2-4]Due to the lack of recognized effective antidotes,many poisoned people suff ocate and die as a result of continuous spasms of the respiratory muscles.[5-7]Tetramine poisoning sometimes occurs,but it is rare for vegetables grown in tetraminecontaminated soil to cause group poisoning after being eaten.

关键词： mortality poisoning vegetables

飞机防滑刹车系统结构谐振一体化设计的仿真研究

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西北工业大学学报 1999年第3期17卷 404-408页

作者：李锋刘刚张瑜第二炮兵工程学院西北工业大学

提出了飞机防滑系统结构谐振一体化设计思想。基于飞机起落架中相应结构的变形与主起落架水平纵向“走步”振动的联系，建立了以整个起落架系统为实验对象的防滑系统惯性台试验系统的数字仿真模型。以该模型为基础，研究了控制器参数对... 详细信息

提出了飞机防滑系统结构谐振一体化设计思想。基于飞机起落架中相应结构的变形与主起落架水平纵向“走步”振动的联系，建立了以整个起落架系统为实验对象的防滑系统惯性台试验系统的数字仿真模型。以该模型为基础，研究了控制器参数对起落架“走步”现象的影响。仿真结果表明，该设计思想的防滑系统综合控制效果较好。

关键词：防滑制动起落架仿真谐振飞机防滑刹车系统

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电控离合器的H_∞控制及鲁棒性分析

上海交通大学学报 2001年第12期35卷 1802-1807页

作者：黄宏成习纲张建武上海交通大学机械工程学院上海200030

将车用电控离合器视为非线性动力系统 ,并在确定性数学模型基础上设计了鲁棒控制器 .为提高电控离合器控制器的鲁棒性 ,引入控制理论 .H∞ 给出性能权函数、鲁棒权函数、控制权函数的选择方法 ,并利用双线性变换解决了临界稳定系统的病... 详细信息

将车用电控离合器视为非线性动力系统 ,并在确定性数学模型基础上设计了鲁棒控制器 .为提高电控离合器控制器的鲁棒性 ,引入控制理论 .H∞ 给出性能权函数、鲁棒权函数、控制权函数的选择方法 ,并利用双线性变换解决了临界稳定系统的病态求解问题 .给定参数变化时 ,该系统的动态仿真结果表明 ,控制器响应 H∞ 快 ,跟踪精度高 ,鲁棒性良好 .

关键词：汽车传动电控离合器鲁棒性控制

Performance enhancement of triboelectric nanogenerator based on BaTiO3-incorporated PVDF-HFP nanofibers for self-powered wearable sensors

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Science China Technological Sciences 2025年第1期 266-273页

作者： Tianjie DENG xi zhang Zhuanqing YANG gang xiANG College of Physics Sichuan University

The triboelectric nanogenerators（TENGs） based on polyvinylidene fluoride（PVDF） have attracted significant attention due to their high energy conversion efficiency and strong flexibility. Indeed, the TENGs with higher electrical performance and stronger mechanical robustness are more desirable. In this context, we design and fabricate TENGs based on nanofiber（NF） layer of Poly（vinylidene fluoridehexafluoropropylene）(PVDF-HFP), a copolymer of PVDF with better mechanical properties, in which the enhancement of dielectric constant and specific surface area is achieved by incorporation of BaTiO3into PVDF-HFP NFs using electrospinning. The results show that the TENGs demonstrates superior electrical performance. The optimized TENG exhibits an open-circuit voltage（VOC） of 432 V, a short-circuit current（ISC） of 44.2 μA, and a maximum power density（Pd） of 2.25 W/m2. Practical applications of the optimized TENG are also demonstrated, including its use as power source, cylindrical rotating energy harvester and self-powered wearable sensor. The findings give insights into the fabrication, performance and application of the TENGs based on BaTiO3-incorporated PVDF-HFP NFs, offering promising solutions for energy harvesting and diverse applications.

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Small extracellular vesicles derived from cerebral endothelial cells with elevated microRNA 27a promote ischemic stroke recovery

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Neural Regeneration Research 2025年第1期20卷 224-233页

作者： Yi zhang Zhongwu Liu Michael Chopp Michael Millman Yanfeng Li Pasquale Cepparulo Amy Kemper Chao Li Li zhang Zheng gang zhang Department of Neurology Henry Ford HospitalDetroitMIUSA Department of Physics Oakland UniversityRochesterMIUSA Department of Pathology Henry Ford HospitalDetroitMIUSA Division of Pharmacology Department of NeuroscienceReproductive and Dentistry SciencesSchool of MedicineUniversity of Naples“Federico Ⅱ”NaplesItaly

Axonal remodeling is a critical aspect of ischemic brain repair processes and contributes to spontaneous functional *** previous in vitro study demonstrated that exosomes/small extracellular vesicles(sEVs)isolated from cerebral endothelial cells(CEC-sEVs)of ischemic brain promote axonal growth of embryonic cortical neurons and that microRNA 27a(miR-27a)is an elevated miRNA in ischemic *** the present study,we investigated whether normal CEC-sEVs engineered to enrich their levels of miR-27a(27a-sEVs)further enhance axonal growth and improve neurological outcomes after ischemic stroke when compared with treatment with non-engineered CEC-sEVs.27a-sEVs were isolated from the conditioned medium of healthy mouse CECs transfected with a lentiviral miR-27a expression *** EVs isolated from CECs transfected with a scramble vector(Scra-sEVs)were used as a *** male mice were subjected to permanent middle cerebral artery occlusion and then were randomly treated with 27a-sEVs or *** array of behavior assays was used to measure neurological *** with treatment of ischemic stroke with Scra-sEVs,treatment with 27a-sEVs significantly augmented axons and spines in the peri-infarct zone and in the corticospinal tract of the spinal grey matter of the denervated side,and significantly improved neurological *** vitro studies demonstrated that CEC-sEVs carrying reduced miR-27a abolished 27a-sEV-augmented axonal *** analysis revealed that 27a-sEVs systemically administered preferentially localized to the pre-synaptic active zone,while quantitative reverse transcription-polymerase chain reaction and Western Blot analysis showed elevated miR-27a,and reduced axonal inhibitory proteins Semaphorin 6A and Ras Homolog Family Member A in the peri-infarct *** of the Clathrin-dependent endocytosis pathway substantially reduced neuronal internalization of *** data provide evidence that 27a-sEVs have

关键词： axonal remodeling cerebral endothelial cells exosomes miR-27a mitochondria Semaphorin 6A small extracellular vesicles stroke

丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞的疗效

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国际眼科杂志 2015年第1期15卷 101-103页

作者：张锡钢吴萍童颖栗印兰中国辽宁省大连市第二人民医院眼科 116011

目的：探讨丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞患者的临床效果,并观察其预后,为临床提供客观依据。方法：随机选择本院2011-01/2014-04收治的早期RVO患者82例117眼,对照组41例59眼,应用蚓激酶治疗;观察组41例58眼,应... 详细信息

目的：探讨丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞患者的临床效果,并观察其预后,为临床提供客观依据。方法：随机选择本院2011-01/2014-04收治的早期RVO患者82例117眼,对照组41例59眼,应用蚓激酶治疗;观察组41例58眼,应用丹参注射液离子导入配合蚓激酶治疗。主要观察指标为治疗效果、观察患者视力恢复情况及视网膜循环时间等指标。结果：观察组总有效率为85.4%（35/41）,高于对照组68.3%（28/41）,差异有统计学意义（P〈0.05）;观察组无效率为14.6%（6/41）,低于对照组31.7%（13/41）,差异有统计学意义（P〈0.05）;观察组视力恢复4.8~5.0为53.7%（22/41）,高于对照组41.5%（17/41）,差异有统计学意义（P〈0.05）;观察组视力恢复4.3~4.7为31.7%（13/41）,低于对照组41.5%（17/41）,差异有统计学意义（P〈0.05）;两组患者治疗后视网膜静脉循环时间,均低于治疗前,差异有统计学意义（P〈0.05）;观察组治疗后视网膜静脉循环时间为8.15±1.30s,低于对照组9.70±1.28s,差异有统计学意义（P〈0.05）。结论：丹参注射液离子导入配合蚓激酶治疗早期视网膜静脉阻塞临床疗效较好,提高患者的视力恢复,促进患者康复。

关键词：视网膜静脉阻塞丹参注射液离子导入蚓激酶

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城市立交桥钢桥面SMA铺装层及其施工技术

施工技术 2004年第9期33卷 10-12页

作者：张希黔罗刚张宏胜张利重庆大学重庆400045

介绍沥青玛蹄脂混合料(SMA)的基本概念,阐述SMA混合料作为城市立交桥钢桥面铺装层的优良性能,以及SMA混合料的拌和生产、摊铺、碾压施工中的主要技术要点。

关键词：钢桥面 SMA混合料施工技术