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Hepatobiliary & Pancreatic Diseases International 2023年第4期22卷 426-429页

作者： Kristen R Szempruch Anne M Lachiewicz Brittney M Williams Aman Kumar xavier Baldwin Chirag S Desai Pharmacy Department University of North Carolina Medical CenterChapel HillNCUSA Division of Infectious Disease University of North Carolina Medical CenterChapel HillNCUSA Department of Surgery TransplantUniversity of North Carolina Medical CenterChapel HillNCUSA

To the Editor:Total pancreatectomy with islet cell autotransplantation(TPIAT)is a viable treatment option upon failed endoscopic and medical therapy for patients with chronic *** procedure involves surgical removal of the entire pancreas,isolation of islet cells and reinfusion of these cells into the liver via portal vein[1,2].The risk of contamination to the final islet cell product can occur at several stages of the isolation procedure[3].In order to ensure the sterility of the islet cell product,multiple samples from the preservation and cannulation solution,and the final islet cell product are sent for bacterial *** studies have found variable clinical consequences of these cultures on infectious com-plications or graft function[3-9].Herein we aimed to determine the incidence of infection in 60 days post-TPIAT and its association with the culture data.

关键词： islet patients viable

The application of extended modified Lambert Beer model for measurement of blood carboxyhemoglobin and oxyhemoglobin saturation

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Journal of Innovative Optical Health Sciences 2014年第3期7卷 108-114页

作者： Audrey Huong xavier Ngu Department.of Electronic Engineering Faculty of Electrical and Electronic Engineering Uiniversity Tun Hussein Onn Malaysia Batu Pahat 86400 JohorMalaysia Department of Communication Engineering Faculty of Electrical and Electronic Engineering University Tun Hussein Onn Malaysia Batu Pahat 86400 JohorMalaysia

This work presents the use of extended Modified Lambert Beer(MLB)model for accurate andcontinuous monitoring of percent blood carboxyhemoglobin(COHb)(SCO)and oxyhemoglobin(OxyHb)saturation(SO,)via a fitting *** quantification technique is based on theabsorption characteristics of hemoglobin derivatives in the wavelength range of 520-600 nm togive the best estimates of the required parameters.A comparison of the performance of the developed model and MILB law is made using attenuation data from Monte Carlo simulations for a two-layered skin *** results revealed a lower mean absolute error of 0.4%in the valuesestimated by the developed model as compared to 10%that is given by the MILB *** studyshowed that the discussed approach is able to provide consistent and accurate measurement ofblood SO,and SCO across diferent skin pigmen tations suggesting that it may potentially be usedas an alternative means for clinical diagnosis of carbon monoxide(CO)poisoning.

关键词： Blood carboxyhemoglobin saturation carbon monoxide poisoning blood oxyhemoglobin saturation modified Lambert Beer law

耐化学腐蚀和疏水性的食品包装用含SnO_(2)生物纳米复合材料

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Transactions of Nonferrous Metals Society of China 2023年第7期33卷 2136-2154页

作者： Joseph Raj xavier CDHANALAKSHMI Shanmuga Sundari CHANDRARAJ SPVINODHINI Department of Chemistry Saveetha School of EngineeringSaveetha Institute of Medical and Technical SciencesChennai-602105Tamil NaduIndia Department of Chemistry Vel Tech Rangarajan Dr.Sagunthala R&D Institute of Science and TechnologyChennai-600062Tamil NaduIndia

研究了聚(天冬酰胺-共苯丙氨酸)(P(Asn-co-Phe)/SnO_(2))对环氧树脂(EP)涂层防护性能的影响。电化学阻抗谱分析表明,与纯环氧树脂涂层相比,马口铁表面EP-P(Asn-co-Phe)/SnO_(2)纳米复合材料涂层具有更好的防护作用。EP-P(Asn-co-Phe)/Sn... 详细信息

研究了聚(天冬酰胺-共苯丙氨酸)(P(Asn-co-Phe)/SnO_(2))对环氧树脂(EP)涂层防护性能的影响。电化学阻抗谱分析表明,与纯环氧树脂涂层相比,马口铁表面EP-P(Asn-co-Phe)/SnO_(2)纳米复合材料涂层具有更好的防护作用。EP-P(Asn-co-Phe)/SnO_(2)纳米复合材料涂层的电阻(Rcoat)为3854.70 kΩ·cm^(2),比环氧树脂涂层的大38倍。扫描电化学显微镜分析表明,EP-P(Asn-co-Phe)/SnO_(2)的电流分布更小。通过XRD和SEM/EDX对降解产物进行分析,证实了功能化SnO_(2)颗粒对环氧树脂涂层防护能力的影响。EP-P(Asn-co-Phe)/SnO_(2)纳米复合材料涂层的水接触角为133°,证实了其疏水性。此外,与纯环氧树脂涂层相比,EP-P(Asn-co-Phe)/SnO_(2)纳米材料复合涂层具有更高的力学性能和抗菌活性。综上,由于在环氧树脂基体中添加了P(Asn-co-Phe)/SnO_(2)纳米颗粒,EP-P(Asn-co-Phe)/SnO_(2)纳米复合材料提供了出色的屏障和力学性能,从而阻碍了材料的降解,有助于延长涂层钢的寿命。

关键词：马口铁环氧树脂 SnO_(2) 纳米材料复合涂层共聚物热稳定性硬度

Intrahepatic Cholangiocarcinoma and Hepatocellular Carcinoma:Real-life Data on Liver Disease,Treatment and Prognosis

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Journal of Clinical and Translational Hepatology 2023年第5期11卷 1106-1117页

作者： xavier Adhoute Olivia Pietri Guillaume Pénaranda Thomas Wolf Patrick Beaurain Olivier Monnet Arthur Laquière Justine Bonomini Frédéric Neumann Olivier Levrel Jean-Pascal Buono xavier Hanna Paul Castellani HervéPerrier Marc Bourliere Rodolphe Anty Department of Gastroenterology and Hepatology Hôpital Saint-JosephMarseilleFrance Department of Biostatistics AlphaBio-Biogroup LaboratoryMarseilleFrance Department of Radiology Hôpital Saint-JosephMarseilleFrance Department of Clinical Research Hôpital Saint-JosephMarseilleFrance Medipath EguillesFrance Department of Hepatobiliary Surgery Hôpital Saint-JosephMarseilleFrance Department of Gastroenterology and Hepatology Hôpital Universitaire de l’ArchetNiceFrance

Background and Aims:Hepatocellular carcinoma(HCC)and intrahepatic cholangiocarcinoma(iCCA)have common features and *** real-life study investigated their characteristics,treatment modalities,and ***:This retrospective comparative study was performed in 1,075 patients seen at one tertiary center between January 2008 and December *** survival(OS)was estimated by the Kaplan-Meier *** of iCCAs after histological and radiological review,and molecular profiling was ***:HCCs patients were more likely to have early-stage disease than iCCA *** patients were more likely to be female,especially those patients without cirrhosis(43%vs.17%).Cirrhosis was prominent among HCC patients(89%vs.34%),but no difference in underlying liver disease among cirrhotic patients was *** of HCC patients was 18.4(95%CI:6.4,48.3)months,that of iCCA patients was 7.0(95%CI:3.4,20.1)*** of Barcelona Clinic Liver Cancer C HCC patients was 7.8(95%CI:4.3,14.2)months,that of advanced/metastatic iCCA patients was 8.5(95%CI:5.7,12.3)*** patients treated with sorafenib,OS was longer in HCC patients who received subsequent tyrosine kinase inhibitor *** significant OS difference was found between iCCA patients with and without cirrhosis or according to histological subtype.A targetable molecular alteration was detected in 50%of the iCCA ***:In this French series,cirrhosis was common in iCCA,which showed etiological factors comparable to those of HCC,implying a distinct oncogenic *** entities had a dismal prognosis at advanced ***,systemic therapies sequencing in HCC and molecular profiling in iCCA offer new insights.

关键词： Intrahepatic cholangiocarcinoma Hepatocellular carcinoma Cirrhosis NASH Oncogenic alterations

Experimental investigation of flow field in a laboratory-scale compressor

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Chinese Journal of Aeronautics 2017年第1期30卷 31-46页

作者： Ma Hongwei Wei Wei xavier Ottavy Key Laboratory of Science and Technology on Aero-Engine Aero-Thermodynamics School of Energy and Power Engineering Beihang University Beijing 100083 China Collaborative Innovation Center of Advanced Aero-Engine Beijing 100083 China China Academy of Aerospace Aerodynamics (CAAA) Yungangxi Rd. Fengtai Dist. Beijing 100074 China Laboratoire de Mecanique des Fluides et d'Acoustique (LMFA) Groupe TurbomachinesEcole Centrale de Lyon 36 av. Guy de Collongue 69134 Ecully cedex France

The inner flow environment of turbomachinery presents strong three-dimensional, rotational, and unsteady characteristics. Consequently, a deep understanding of these flow phenomena will be the prerequisite to establish a state-of-the-art design system of turbomachinery. Currently the development of more accurate turbulence models and CFD tools is in urgent need for a high-quality database for validation, especially the advanced CFD tools, such as large eddy simulation（LES）. Under this circumstance, this paper presents a detailed experimental investigation on the 3D unsteady flow field inside a laboratory-scale isolated-rotor with multiple advanced measurement techniques, including traditional aerodynamic probes, hotwire probes, unsteady endwall static pressure measurement, and stereo particle image velocimetry（SPIV）. The inlet boundary layer profile is measured with both hotwire probe and aerodynamic probe. The steady and unsteady flow fields at the outlet of the rotor are measured with a mini five-hole probe and a single-slanted hotwire probe. The instantaneous flow field in the rotor tip region inside the passage is captured with SPIV,and then a statistical analysis of the spatial distribution of the instantaneous tip leakage vortex/flow is performed to understand its dynamic characteristics. Besides these, the uncertainty analysis of each measurement technique is described. This database is quite sufficient to validate the advanced numerical simulation with LES. The identification process of the tip leakage vortex core in the instantaneous frames obtained from SPIV is performed deliberately. It is concluded that the ensemble-averaged flow field could not represent the tip leakage vortex strength and the trajectory trace. The development of the tip leakage vortex could be clearly cataloged into three phasesaccording to their statistical spatial distribution. The streamwise velocity loss induced by the tip leakage flow increases until the splitting process is weak

关键词： Database Laboratory-scale compres-sor SPIV Tip leakage flow Tip leakage vortex

Vigilance behavior of Pyrenean chamois Rupicapra pyrenaica pyrenaica:Effect of sex and position in the herd

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Current Zoology 2010年第2期56卷 232-237页

作者： Antoni DALMAU Alfred FERRET xavier MANTECA Irta Finca Camps i Armet s/n Monells Universitat Autònoma de Barcelona School of Veterinary Science Departament de Ciència Animal i dels Aliments

The Pyrenean chamois Rupicapra pyrenaica pyrenaica is a mountain-dwelling ungulate with an extensive presencein open areas. Optimal group size results from the trade off between advantages (a reduction in the risk of predation) and disadvantages(competition between members of the herd) of group living. In addition, advantages and disadvantages of group livingmay vary depending on the position of each individual within the herd. Our objective was to study the effect of central vs. peripheralposition in the herd on feeding and vigilance behavior in male and female Pyrenean chamois and to ascertain if a group sizeeffect existed. We used focal animal sampling and recorded social interactions when a focal animal was involved. With males,vigilance rate was higher in the central part of the group than at the periphery, probably due to a higher density of animals in thecentral part of the herd and a higher probability of being disturbed by conspecifics. With females, vigilance rate did not differ accordingto position in the herd. Females spent more time feeding than males, and males showed a higher frequency of the vigilancebehavior than females. We did not observe a clear relationship between group size and vigilance behavior. The differencesin vigilance behavior might be due to social

关键词：警戒行为位置效应牛群羚羊性别社会交往捕食风险规模效应

Ionic thermoelectric materials and devices

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Journal of Energy Chemistry 2021年第10期30卷 88-103,I0003页

作者： Dan Zhao Alois Würger xavier Crispin Laboratory of Organic Electronics Linkoping UniversityNorrkoping 60247Sweden Univ.Bordeaux&CNRS LOMA(UMR 5798)F-33405 TalenceFrance Wallenberg Wood Science Center ITNLinköping UniversityNorrköpingSweden

The tremendous amount of wasted heat from solar radiation and industry dissipation has motivated the development of thermoelectric concepts that directly convert heat into *** main challenge in practical applications for thermoelectrics is the high cost from both materials and ***,breakthrough progresses in ionic thermoelectrics open up new possibilities to charge energy storage devices when submitted to a temperature *** charging voltage is internally from the ionic Seebeck effect of the electrolyte between two *** electrolytes with high thermoelectric figure of merit are classified as ionic thermoelectric *** ionic thermoelectric materials are composed of abundant elements,and they can generate hundreds of times larger thermal voltage than that of electronic *** emerging thermoelectric category brings new hope to fabricate low cost and large area heat-to-energy conversion devices,and triggers a renewed interest for ionic *** this review,we summarize the state of the art in the new field of ionic thermoelectrics,from the driving force of the ionic thermodiffusion to material and application *** present a general map of ionic thermoelectric materials,discuss the unique characters of each type of the reported electrolytes,and propose potential optimization and future topics of ionic thermoelectrics.

关键词： Electrolytes Soret effect Thermodiffusion Thermal energy conversion

Multi-gigahertz mode-locked femtosecond Yb:KLuW waveguide lasers

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Photonics Research 2022年第11期10卷 2584-2589页

作者： JI EUN BAE xavier MATEOS MAGDALENA AGUILÓ FRANCESC DÍAZ JAVIER GARCÍA AJATES CAROLINA ROMERO JAVIER RODRÍGUEZ VÁZQUEZ DE ALDANA FABIAN ROTERMUND Department of Physics Korea Advanced Institute of Science and Technology(KAIST)34141 DaejeonRepublic of Korea Universitat Rovira i Virgili(URV) Fı´sica i Cristal·lografia de Materials i Nanomaterials(FiCMA)43007 TarragonaSpain Grupo de Investigación en Aplicaciones del Láser y Fotónica University of Salamanca37008 SalamancaSpain

We demonstrate multi-gigahertz continuous-wave mode-locking of a Yb:KLuW waveguide laser. A femtosecondlaser-inscribed Yb:KLuW channel waveguide in an extended laser cavity delivers a fundamentally mode-locked laser near 1030 nm. A tunable few-centimeter-long cavity containing a single-walled carbon nanotube saturable absorber as mode-locker generates self-starting femtosecond pulses with average output powers exceeding210 mW at repetition rates of 2.27, 2.69, and 3.55 GHz. The laser cavity, which includes a wedged waveguide,is extended by using a lens pair that controls the laser fluence on the saturable absorber for reliable mode-locked operation without instability. The presented laser performance, mode-locked up to 3.55 GHz, highly suggests the potential of crystalline Yb:KLuW waveguides for realizing high-power ultrafast lasers with higher GHz repetition rates in a quasi-monolithic cavity.

关键词： waveguide femtosecond mode

Underlying solvent-based factors that influence permanent porosity in porous liquids

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Nano Research 2022年第4期15卷 3533-3538页

作者： Hamidreza Mahdavi Huacheng Zhang Lauren K.Macreadie Cara M.Doherty Durga Acharya Stefan J.DSmith xavier Mulet Matthew R.Hill Department of Chemical Engineering Monash UniversityClaytonVIC 3800Australia CSIRO Manufacturing Private Bag 10Clayton SouthVIC 3169Australia School of Chemistry University of SydneySydney 2006Australia

Porous liquids(PLs)offer the potential to combine the ready handling and mature industry status of liquid absorbents,with the high permanent porosity of metal organic *** be functional,these nanocomposites need to satisfy a number of performance parameters,such as stability and viscosity of the porogen-solvent combination,avoiding solvent penetration into metal organic framework(MOF)pores,suitable capacities,and kinetics for gas *** this work,we systematically investigate the component materials to elucidate the parametric space where stable photoluminescence(PL)can be *** this situation,deeper conclusions were able to be drawn with regard to the influence of hydrophobicity/philicity on the properties of the resulting *** imidazolate frameworks(ZIFs)were combined with a range of solvents varying in steric bulk,to deliver CO_(2)sorption capacities as high as 4.2 mmol·g^(-1)at 10 *** findings may have broader implications for future investigations of this tantalising field of nanocomposites.

关键词： zeolitic imidazolate frameworks porous liquids permanent porosity gas sorption

Selective and taxon-dependent effects of semi-feral cattle grazing on tree regeneration in an old-growth Mediterranean mountain forest

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Forest Ecosystems 2020年第1期7卷 128-140页

作者： xavier Fortuny Christopher Carcaillet Sandrine Chauchard Ecole Pratique des Hautes Etudes(EPHE) PSL University75014 ParisFrance Laboratoire d’ cologie des Hydrosystèmes Naturels et Anthropisés(UMR5023 CNRS UniversitéLyon 1ENTPE)69622 VilleurbanneFrance Universitéde Lorraine AgroParisTechINRAEUMR Silva54000 NancyFrance

Background:In Mediterranean mountain socio-ecosystems,both grazing by livestock and the dry season may influence tree ***,the relative contributions of these drivers are poorly known,even though present and future canopy composition might result from past and present variations in climate and herbivore *** study aims to test how semi-feral cattle presence and season affect tree ***:The study was conducted using permanent plots inside and outside a cattle exclosure in an old-growth Mediterranean *** and seedlings were counted five times per year(winter,early spring,middle spring,summer,fall)and monitored over 7 ***:Semi-feral cattle exclusion increased Acer,Fagus,Ilex,Pinus,Prunus and Quercus sapling densities and increased Acer,Fraxinus,Ilex,Quercus and Sorbus seedling ***,the dry season did not exert any noticeable effects on the sapling or seedling densities of any of the studied ***:Semi-feral cattle presence may limit tree regeneration through taxon-dependent effects,which suggests that the current decrease in grazing livestock across the Mediterranean basin will modify recruitment processes and,likely,future forest ***:Semi-feral cattle presence acts as a selective driver of tree community composition.

关键词： Cattle Climate Experiment Herbivory Forest pastoralism