The application of extended modified Lambert Beer model for measurement of blood carboxyhemoglobin and oxyhemoglobin saturation

作     者：Audrey Huong Xavier Ngu 

作者机构：Department.of Electronic Engineering Faculty of Electrical and Electronic Engineering Uiniversity Tun Hussein Onn Malaysia Batu Pahat 86400JohorMalaysia Department of Communication Engineering Faculty of Electrical and Electronic Engineering University Tun Hussein Onn Malaysia Batu Pahat 86400JohorMalaysia 

出 版 物：《Journal of Innovative Optical Health Sciences》 (创新光学健康科学杂志（英文）)

年 卷 期：2014年第7卷第3期

页      面：108-114页

核心收录：

学科分类：0831[工学-生物医学工程（可授工学、理学、医学学位）] 1004[医学-公共卫生与预防医学(可授医学、理学学位)] 0808[工学-电气工程] 0809[工学-电子科学与技术（可授工学、理学学位）] 08[工学] 0805[工学-材料科学与工程（可授工学、理学学位）] 0836[工学-生物工程] 0702[理学-物理学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

主　　题：Blood carboxyhemoglobin saturation carbon monoxide poisoning blood oxyhemoglobin saturation modified Lambert Beer law 

摘      要：This work presents the use of extended Modified Lambert Beer(MLB)model for accurate andcontinuous monitoring of percent blood carboxyhemoglobin(COHb)(SCO)and oxyhemoglobin(OxyHb)saturation(SO,)via a fitting *** quantification technique is based on theabsorption characteristics of hemoglobin derivatives in the wavelength range of 520-600 nm togive the best estimates of the required parameters.A comparison of the performance of the developed model and MILB law is made using attenuation data from Monte Carlo simulations for a two-layered skin *** results revealed a lower mean absolute error of 0.4%in the valuesestimated by the developed model as compared to 10%that is given by the MILB *** studyshowed that the discussed approach is able to provide consistent and accurate measurement ofblood SO,and SCO across diferent skin pigmen tations suggesting that it may potentially be usedas an alternative means for clinical diagnosis of carbon monoxide(CO)poisoning.