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中国北方兴隆遗址早期农业人群对木材的利用和管理

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中国科学：地球科学 2024年第6期54卷 1937-1949页

作者：沈慧邱振威赵克良周新郢李小强中国科学院古脊椎动物与古人类研究所脊椎动物演化与人类起源重点实验室北京100044 中国国家博物馆北京100006 中国科学院大学地球与行星科学学院北京100049

农业起源、发展及其与植被环境间关系是环境考古学研究的热点科学问题.本文选择我国北方新石器时代兴隆遗址,针对木炭遗存进行种属鉴定和年轮曲率统计等系统分析,重建了兴隆遗址局地林地植被环境,揭示了早期黍粟农业人群对林地的利用、... 详细信息

农业起源、发展及其与植被环境间关系是环境考古学研究的热点科学问题.本文选择我国北方新石器时代兴隆遗址,针对木炭遗存进行种属鉴定和年轮曲率统计等系统分析,重建了兴隆遗址局地林地植被环境,揭示了早期黍粟农业人群对林地的利用、改造和适应.研究结果显示,兴隆遗址周围曾经分布有丰富的林地植被,包括山杏(Prunus sibirica)灌丛,榆属(Ulmus)、槭属(Acer)疏林,杨属(Populus)林地等.距今8000~7000年时期,中国北方地区温暖湿润的气候环境可能促使了槭属、鼠李属(Rhamnus)、圆柏属(Juniperus)等木本植物的广泛分布以及早期黍粟旱作农业的快速发展.其中,大量可食用李属植物的发现,可能指示了丰富的果树林地的存在,成为早期黍粟农业聚落的重要植被组成.结合不同植物生境分布信息,兴隆先民对聚落周边木材资源有着充分利用,杨属和榆属植物是最主要的薪材来源.木炭年轮曲率统计结果显示,兴隆先民主要利用榆属、杨属、槭属和圆柏属的枝干或者较粗的枝条部位作为薪材,在8000~7000a BP时期可能已经开始通过植株修剪、砍伐非果树类植物等方式对山杏灌丛进行有意识的保护和管理,以获取更多的果类食物资源,显示了早期黍粟农业人群适应和影响植被生态的方式和策略.

关键词：兴隆遗址木炭木材利用林地管理

Two-dimensional silica enhanced solid polymer electrolyte for lithium metal batteries

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Particuology 2024年第2期85卷 146-154页

作者： zhihong Luo Weiyong Li Chong Guo Ya Song Mingxia zhou Yan Shi Jing xu Long Li Bin Shi Quansheng Ouyang Jiao-jing Shao Guangmin zhou School of Materials and Metallurgy Guizhou UniversityGuiyang550025China State Key Laboratory of Advanced Chemical Power Sources Zunyi563003China Graphene Materials Engineering Research Center of Guizhou Colleges and Universities Guiyang550025China Tsinghua-Berkeley Shenzhen Institute&Tsinghua Shenzhen International Graduate Schoo Tsinghua UniversityShenzhen518055China

Solid polymer electrolytes(SPEs)are promising substitutes for current flammable liquid electrolytes to achieve high-safety and high-energy-density lithium metal *** oxide(PEO)based solid polymer electrolytes have attracted increasing attention because of their excellent flexibility,manufacturability,light weight,and low-cost processing,while they often suffer from low ionic con-ductivity at room temperature,low lithium transference number and unsatisfactory interfacial resis-tance,which largely restrain their practical ***,two-dimensional holey silica nanosheets(2D-HSN)as the fillers,together with LiNO_(3) as the electrolyte additive,are introduced in a PEO/poly(-vinylidene fiuoride-co-hexafluoropropylene)(PVDF-HFP)blended polymer matrix to obtain a *** incorporation of HSN filler creates supplementary channels for lithium ion migration and lowers the crystallinity of the polymer,thereby facilitating the movement of lithium *** HSN-based SPE demonstrates higher ionic conductivity up to 3.7 x 10-4 S cm-1 at 30℃,larger Li+transference number close to 0.34,and more stable lithium plating/stripping than that without the fillers,and HSN can promote the formation of more stable solid electrolyte interphase(SEI)*** as-assembled LiFePO4||Li batteries deliver a high specific capacity of 159 mA h g-1 with the capacity retention of 95.5%after 200 cycles at 30℃,as well as superior rate performance and cycling stability compared to that using the blank SPE.

关键词： Vermiculite nanosheets Two-dimensional silica Solid polymer electrolytes FillersLithium metal batteries

Cancer stem cells: advances in knowledge and implications for cancer therapy

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Signal Transduction and Targeted Therapy 2024年第8期9卷 3242-3304页

作者： xianjing Chu Wentao Tian Jiaoyang Ning Gang xiao Yunqi zhou ziqi Wang zhuofan zhai Guilong Tanzhu Jie Yang Rongrong zhou Department of Oncology Xiangya HospitalCentral South UniversityChangsha 410008China Department of Dermatology Xiangya HospitalCentral South UniversityChangsha 410008China xiangya Lung Cancer Center Xiangya HospitalCentral South UniversityChangsha 410008China National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan Province 410008China

Cancer stem cells(CSCs),a small subset of cells in tumors that are characterized by self-renewal and continuous proliferation,lead to tumorigenesis,metastasis,and maintain tumor *** continues to be a significant global disease *** the past,surgery,radiotherapy,and chemotherapy were the main cancer *** technology of cancer treatments continues to develop and advance,and the emergence of targeted therapy,and immunotherapy provides more options for patients to a certain ***,the limitations of efficacy and treatment resistance are still *** review begins with a brief introduction of the historical discoveries,original hypotheses,and pathways that regulate CSCs,such as WNT/β-Catenin,hedgehog,Notch,NFkB,JAK/STAT,TGF-β,PI3K/AKT,PPAR pathway,and their *** focus on the role of CSCs in various therapeutic outcomes and resistance,including how the treatments affect the content of CSCs and the alteration of related molecules,CSCs-mediated therapeutic resistance,and the clinical value of targeting CSCs in patients with refractory,progressed or advanced *** summary,CSCs affect therapeutic efficacy,and the treatment method of targeting CSCs is stll difficult to *** regulatory mechanisms and targeting biomarkers of CSCs is currently the mainstream idea.

关键词： Cancer maintain knowledge

Amplitude analysis of the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)

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Chinese Physics C 2024年第8期48卷 6-33页

作者： M.Ablikim M.N.Achasov P.Adlarson O.Afedulidis x.C.Ai R.Aliberti A.Amoroso Q.An Y.Bai O.Bakina I.Balossino Y.Ban H.-R.Bao V.Batozskaya K.Begzsuren N.Berger M.Berlowski M.Bertani D.Bettoni F.Bianchi E.Bianco A.Bortone I.Boyko R.A.Briere A.Brueggemann H.Cai x.Cai A.Calcaterra G.F.Cao N.Cao S.A.Cetin J.F.Chang W.L.Chang G.R.Che G.Chelkov C.Chen C.H.Chen Chao Chen G.Chen H.S.Chen M.L.Chen S.J.Chen S.L.Chen S.M.Chen T.Chen x.R.Chen x.T.Chen Y.B.Chen Y.Q.Chen z.J.Chen z.Y.Chen S.K.Choi x.Chu G.Cibinetto F.Cossio J.J.Cui H.L.Dai J.P.Dai A.Dbeyssi R.E.de Boer D.Dedovich C.Q.Deng z.Y.Deng A.Denig I.Denysenko M.Destefanis F.De Mori B.Fang S.S.Fang W.x.Fang Y.Fang Y.Q.Fang R.Farinelli L.Fava F.Feldbauer G.Felici C.Q.Feng J.H.Feng Y.T.Feng K.Fischer M.Fritsch C.D.Fu J.L.Fu Y.W.Fu H.Gao Y.N.Gao Yang Gao S.Garbolino I.Garzia P.T.Ge z.W.Ge C.Geng E.M.Gersabeck B.Ding x.x.Ding Y.Ding Y.Ding J.Dong L.Y.Dong M.Y.Dong x.Dong M.C.Du S.x.Du z.H.Duan P.Egorov Y.H.Fan J.Fang JA.Gilman K.Goetzen L.Gong W.x.Gong W.Gradl S.Gramigna M.Greco M.H.Gu Y.T.Gu C.Y.Guan z.L.Guan A.Q.Guo L.B.Guo M.J.Guo R.P.Guo Y.P.Guo A.Guskov J.Gutierrez K.L.Han T.T.Han x.Q.Hao F.A.Harris K.K.He K.L.He F.H.Heinsius C.H.Heinz Y.K.Heng C.Herold T.Holtmann P.C.Hong G.Y.Hou x.T.Hou Y.R.Hou z.L.Hou B.Y.Hu H.M.Hu J.F.Hu T.Hu Y.Hu G.S.Huang K.x.Huang L.Q.Huang x.T.Huang Y.P.Huang T.Hussain F.H\"olzken N.H\"usken N.in der Wiesche M.Irshad J.Jackson S.Janchiv J.H.Jeong Q.Ji Q.P.Ji W.Ji x.B.Ji x.L.Ji Y.Y.Ji x.Q.Jia z.K.Jia D.Jiang H.B.Jiang P.C.Jiang S.S.Jiang T.J.Jiang x.S.Jiang Y.Jiang J.B.Jiao J.K.Jiao z.Jiao S.Jin Y.Jin M.Q.Jing x.M.Jing T.Johansson S.Kabana N.Kalantar-Nayestanaki x.L.Kang x.S.Kang M.Kavatsyuk B.C.Ke V.Khachatryan A.Khoukaz R.Kiuchi O.B.Kolcu B.Kopf M.Kuessner x.Kui A.Kupsc W.K\"uhn J.J.Lane P.Larin L.Lavezzi T.T.Lei z.H.Lei H.Leithoff M.Lellmann T.Lenz C.Li C.Li C.H.Li Cheng Li D.M.Li F.Li G.Li H.Li H.B.Li H.J.Li H.N.Li Hui Li J.R.Li J.S.Li K.Li L.J.Li L.K.Li Lei Li M.H.Li P.R.Li Q.M.Li Q.x.Li R.Li S.x.Li T.Li W.D.Li W.G.Li x.Li x.H.Li x.L.Li x.Y.Li Y Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Beihang University Beijing 100191China Bochum Ruhr-University D-44780 BochumGermany Budker Institute of Nuclear Physics SB RAS(BINP) Novosibirsk 630090Russia Carnegie Mellon University PittsburghPennsylvania 15213USA Central China Normal University Wuhan 430079China Central South University Changsha 410083China China Center of Advanced Science and Technology Beijing 100190China China University of Geosciences Wuhan 430074China Chung-Ang University Seoul06974Republic of Korea COMSATS University Islamabad Lahore CampusDefence RoadOff Raiwind Road54000 LahorePakistan Fudan University Shanghai 200433China GSI Helmholtzcentre for Heavy Ion Research GmbH D-64291 DarmstadtGermany Guangxi Normal University Guilin 541004China Guangxi University Nanning 530004China Hangzhou Normal University Hangzhou 310036China Hebei University Baoding 071002China Helmholtz Institute Mainz Staudinger Weg 18D-55099 MainzGermany Henan Normal University Xinxiang 453007China Henan University Kaifeng 475004China Henan University of Science and Technology Luoyang 471003China Henan University of Technology Zhengzhou 450001China Huangshan College Huangshan 245000China Hunan Normal University Changsha 410081China Hunan University Changsha 410082China Indian Institute of Technology Madras Chennai 600036India Indiana University BloomingtonIndiana 47405USA INFN Laboratori Nazionali di Frascati INFN Laboratori Nazionali di FrascatiI-00044FrascatiItaly INFN Laboratori Nazionali di Frascati INFN Sezione di PerugiaI-06100PerugiaItaly INFN Laboratori Nazionali di Frascati University of PerugiaI-06100PerugiaItaly INFN Sezione di Ferrara INFN Sezione di FerraraI-44122FerraraItaly INFN Sezione di Ferrara University of FerraraI-44122FerraraItaly Inner Mongolia University Hohhot 010021China Institute of Modern Physics Lanzhou 730000China Institute of Physics and Technology Peace Avenue 54BUlaanbaatar 13330Mongolia Instituto de A

Using e^(+)e^(−)annihilation data corresponding to an integrated luminosity of 2.93 fb^(−1)taken at the center-of-mass energy√s=3.773 GeV with the BESIII detector,a joint amplitude analysis is performed on the decays D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η).The fit fractions of individual components are obtained,and large interferences among the dominant components of the decays D^(0)→a_(1)(1260)π,D^(0)→π(1300)π,D^(0)→ρ(770)ρ(770),and D^(0)→2(ππ)_(S)are observed in both *** the obtained amplitude model,the CP-even fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are determined to be(75.2±1.1_(stat).±1.5_(syst.))%and(68.9±1.5_(stat).±2.4_(syst.))%,*** branching fractions of D^(0)→π^(+)π^(−)π^(+)π^(−)and D^(0)→π^(+)π^(−)π^(0)π^(0)(non-η)are measured to be(0.688±0.010_(stat.)±0.010_(syst.))%and(0.951±0.025_(stat.)±0.021_(syst.))%,*** amplitude analysis provides an important model for the binning strategy in measuring the strong phase parameters of D^(0)→4πwhen used to determine the CKM angleγ(ϕ_(3))via the B^(−)→DK^(−)decay.

关键词： BESIII D^(0)meson decays amplitude analysis CP-even fraction

Helicobacter pylori mediated niche environment aberrations promote the progression of gastric cancer

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Genes & Diseases 2024年第5期11卷 113-116页

作者： Teng Yan Hang Sun Yuhui Liao Jiajian zhou Nanfang Hospital The First School of Clinical MedicineSouthern Medical UniversityGuangzhouGuangdong 510515China Dermatology Hospital Southern Medical UniversityGuangzhouGuangdong 510091China

Intestinal metaplasia(IM)is a key stage in the tumorigenic Correa cascade from gastritis to final intestinal-type gastric cancer(GC).1 Helicobacter pylori(***)infection is the most common trigger of IM,and it promotes GC progression through induction of gastric epithelial transition.2 Currently,the mechanism by which *** infection promotes tumorigenesis in IM patients is poorly *** et *** a single-cell transcriptomic atlas on premalignant lesions and identified biomarkers of gastric early-malignant cells,providing an opportunity to explore the molecular mechanism of GC progression at the molecular level.

关键词： gastric pylori Helicobacter

Graph neural network-based scheduling for multi-UAV-enabled communications in D2D networks

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Digital Communications and Networks 2024年第1期10卷 45-52页

作者： Pei Li Lingyi Wang Wei Wu Fuhui zhou Baoyun Wang Qihui Wu Nanjing University of Posts and Telecommunications Nanjing210023China Nanjing University of Aeronautics and Astronautics Nanjing210016China

In this paper,we jointly design the power control and position dispatch for Multi-Unmanned Aerial Vehicle(UAV)-enabled communication in Device-to-Device(D2D)*** objective is to maximize the total transmission rate of Downlink Users(DUs).Meanwhile,the Quality of Service(QoS)of all D2D users must be *** comprehensively considered the interference among D2D communications and downlink *** original problem is strongly non-convex,which requires high computational complexity for traditional optimization *** to make matters worse,the results are not necessarily globally *** this paper,we propose a novel Graph Neural Networks(GNN)based approach that can map the considered system into a specific graph structure and achieve the optimal solution in a low complexity ***,we first construct a GNN-based model for the proposed network,in which the transmission links and interference links are formulated as vertexes and edges,***,by taking the channel state information and the coordinates of ground users as the inputs,as well as the location of UAVs and the transmission power of all transmitters as outputs,we obtain the mapping from inputs to outputs through training the parameters of *** results verified that the way to maximize the total transmission rate of DUs can be extracted effectively via the training on ***,it also shows that the performance of proposed GNN-based method is better than that of traditional means.

关键词： Unmanned aerial vehicle D2 Dcommunication Graph neural network Power control Position planning

Detector-integrated vertical-cavity surfaceemitting laser with a movable high-contrast grating mirror

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Photonics Research 2024年第7期12卷 1437-1448页

作者： MINGLU WANG HONGLING PENG CHENxI HAO xUYAN zhou WANHUA zHENG ANJIN LIU Key Laboratory of Optoelectronic Materials and Devices Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of SciencesBeijing 100049China School of Electronic Electrical and Communication EngineeringUniversity of Chinese Academy of SciencesBeijing 100049China Key Laboratory of Solid-State Optoelectronics Information Technology Institute of SemiconductorsChinese Academy of SciencesBeijing 100083China

In this paper, we present a detector-integrated vertical-cavity surface-emitting laser(VCSEL) with a movable high-contrast grating(HCG) mirror in an n-i-p-i-n manner. The detector-integrated VCSEL with a movable HCG can achieve three functions, including wavelength tuning, power monitoring, and resonant-cavity-enhanced(RCE)photon detection. Currently, the device can achieve a wavelength tuning range of 27 nm at room temperature when the suspended HCG is driven by the reverse-bias voltage. The n-i-p structure located at the upper part of the device can serve as an intra-cavity photodiode to monitor the output power due to the defect absorption. The RCE photon detection function of the detector-integrated VCSEL with a movable HCG is measured, and it has a peak responsivity at about 926 nm. This detector-integrated VCSEL with a movable HCG will be useful for sensing and imaging.

关键词： tuning laser cavity

The biosynthesis of asiaticoside and madecassoside reveals tandem duplication-directed evolution of glycoside glycosyltransferases in the Apiales

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Plant Communications 2024年第10期5卷 166-179页

作者： xiaoyang Han Jingyi zhao Hong zhou xuan zhou zixin Deng zhenhua Liu Yi Yu Department of Gastroenterology Zhongnan Hospital of Wuhan UniversityHubei Clinical Center and Key Laboratory of Intestinal and Colorectal DiseaseSchool of Pharmaceutical SciencesWuhan UniversityWuhan 430071China Joint Center for Single Cell Biology School of Agriculture and BiologyShanghai Jiao Tong UniversityShanghai 200240China State Key Laboratory of Non-Food Biomass and Enzyme Technology Guangxi Academy of SciencesNanning 530007China

Certain plant species within the Apiales order accumulate triterpenoid saponins that feature a distinctive glucose-glucose-rhamnose(G-G-R)sugar chain attached at the C-28 position of the pentacyclic triterpene *** recently,the genomic basis underlying the biosynthesis and evolution of this sugar chain has remained *** this study,we identified two novel glycoside glycosyltransferases(GGTs)that can sequentially install the sugar chain’s second D-glucose and third L-rhamnose during the biosynthesis of asiaticoside and madecassoside,two representative G-G-R sugar chain-containing triterpenoid saponins produced by Centella *** assays revealed the remarkable substrate promiscuity of the two GGTs and the key residues crucial for sugar-donor selectivity of the glucosyltransferase and rhamnosyl*** further identified syntenic tandem gene duplicates of the two GGTs in the Apiaceae and Araliaceae families,suggesting a well-conserved genomic basis underlying sugar chain assembly that likely has evolved in the early ancestors of the Apiales ***,expression patterns of the two GGTs in pierced leaves of *** were found to be correlated with the production of asiaticoside and madecassoside,implying their involvement in host defense against herbivores and *** work sheds light on the biosynthesis and evolution of complex saponin sugars,paving the way for future engineering of diverse bioactive triterpenoids with unique glycoforms.

关键词： triterpenoid saponin glycoside glycosyltransferases biosynthesis asiaticoside madecassoside Centella asiatica

Polyethylene glycol fusion repair of severed rat sciatic nerves reestablishes axonal continuity and reorganizes sensory terminal fields in the spinal cord

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Neural Regeneration Research 2025年第7期20卷 2095-2107页

作者： Emily A.Hibbard Liwen zhou Cathy z.Yang Karthik Venkudusamy Yessenia Montoya Alexa Olivarez George D.Bittner Dale R.Sengelaub Program in Neuroscience Indiana UniversityBloomingtonINUSA Department of Neuroscience University of Texas at AustinAustinTXUSA

Peripheral nerve injuries result in the rapid degeneration of distal nerve segments and immediate loss of motor and sensory functions;behavioral recovery is typically *** used a plasmalemmal fusogen,polyethylene glycol(PEG),to immediately fuse closely apposed open ends of severed proximal and distal axons in rat sciatic *** have previously reported that sciatic nerve axons repaired by PEG-fusion do not undergo Wallerian degeneration,and PEG-fused animals exhibit rapid(within 2–6 weeks)and extensive locomotor ***,our previous report showed that PEG-fusion of severed sciatic motor axons was non-specific,i.e.,spinal motoneurons in PEG-fused animals were found to project to appropriate as well as inappropriate target *** this study,we examined the consequences of PEG-fusion for sensory axons of the sciatic *** adult male and female rats(Sprague–Dawley)received either a unilateral single cut or ablation injury to the sciatic nerve and subsequent repair with or without(Negative Control)the application of *** action potentials recorded immediately after PEG-fusion repair confirmed conduction across the injury *** success of PEG-fusion was confirmed through Sciatic Functional Index testing with PEG-fused animals showing improvement in locomotor function beginning at 35 days *** 2–42 days postoperatively,we anterogradely labeled sensory afferents from the dorsal aspect of the hindpaw following bilateral intradermal injection of wheat germ agglutinin conjugated horseradish ***-fusion repair reestablished axonal *** to unoperated animals,labeled sensory afferents ipsilateral to the injury in PEG-fused animals were found in the appropriate area of the dorsal horn,as well as inappropriate mediolateral and rostrocaudal ***,despite having intact peripheral nerves,similar reorganizations of labeled sensory afferents were also observed contralateral to the injury and repa

关键词： axotomy dorsal horn peripheral nerve injury plasticity polyethylene glycol(PEG) sciatic nerve sensory terminals wheat germ agglutinin horseradish peroxidase