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世界核心医学期刊文摘（心脏病学分册） 2006年第11期2卷 3-4页

作者： Hock ong M.e. Ornato J.P. edwards D.P. 任付先 Department of emergency Medicine Virginia Commonwealth University Medical Center 1250 E Marshall St Richmond VA 23298-0401 United States Dr.

Context: Only 1%to 8%of adults with out-of-hospital cardiac arrest survive to hospital discharge. Objective: To compare resuscitation outcomes before and after an urban emergency medical services(eMS) system switched from manual cardiopulmonary resuscitation(CPR) to load-distributing band(LDB) CPR. Design, Setting, and Patients: A phased, observational cohort evaluation with intention-to-treat analysis of 783 adults with out-of-hospital, nontraumatic cardiac arrest. A total of 499 patients were included in the manual CPR phase(January 1, 2001, to March 31, 2003) and 284 patients in the LDB-CPR phase(December 20, 2003, to March 31, 2005); of these patients, the LDB device was applied in 210 patients. Intervention: Urban eMS system change from manual CPR to LDB-CPR. Main Outcome Measures: Return of spontaneous circulation(ROSC), with secondary outcome measures of survival to hospital admission and hospital discharge, and neurological outcome at discharge. Results:Patients in the manual CPR and LDB-CPR phases were comparable ex.ept for a faster response time interval(mean difference, 26 seconds) and more eMS-witnessed arrests(18.7%vs 12.6%) with LDB. Rates for ROSC and survival were increased with LDB-CPR compared with manual CPR(for ROSC, 34.5%; 95%confidence interval[CI], 29.2%-40.3%vs 20.2%; 95%CI, 16.9%-24.0%; adjusted odds ratio[OR], 1.94; 95%CI, 1.38-2.72; for survival to hospital admission, 20.9%; 95%CI, 16.6%-26.1%vs 11.1%; 95%CI, 8.6%-14.2%; adjusted OR, 1.88; 95%CI, 1.23-2.86; and for survival to hospital discharge, 9.7%; 95%CI, 6.7%-13.8%vs 2.9%; 95%CI, 1.7%-4.8%; adjusted OR, 2.27; 95%CI, 1.11-4.77). In secondary analysis of the 210 patients in whom the LDB device was applied, 38 patients(18.1%) survived to hospital admission(95%CI, 13.4%-23.9%) and 12 patients(5.7%) survived to hospital discharge(95%CI, 3.0%-9.3%). Among patients in the manual CPR and LDB-CPR groups who survived to hospital discharge, there was no significant difference between groups in C

关键词：胸部按压心脏停搏复苏效果心肺复苏急救服务城市医疗治疗人数动负荷自主循环脑功能

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A New Measurement of ^11Be(p,d) Transfer Reaction

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Chinese Physics Letters 2018年第8期35卷 14-18页

作者： Ying Jiang Jian-Ling Lou Yan-Lin Ye Dan-Yang Pang Jie Chen Zhi-Huan Li Yu-Cheng Ge Qi-Te Li Jing Li Wei Jiang Ye-Lei Sun Hong-Liang Zang Yun Zhang Wei Liu Gen Li N.Aoi e.Ideguchi H.J.ong J.Lee Jin Wu Hong-Na Liu Chao Wen Y.Ayyad K.Hatanaka D.T.Tran T.Yamamoto M.Tanaka T.Suzuki T.T.Nguyen School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University Beijing 100871 School of Physics and Nuclear energy engineering Beijing Key Laboratory of Advanced Nuclear Materials and Physics Beihang University Beijing 100191 Research Centre for Nuclear Physics Osaka university Osaka 567-0047 Japan Institute of Physical and Chemical Research Saitama 351-0198 Japan

A new ^11Be（p,d） transfer reaction ex.eriment is performed in inverse kinematics with a radioactive11 Be beam at26.9 MeV. Three low-lying states, namely the 0＋ground state, the 2^＋ state at ex = 3.37 MeV, and the multiplet at around 6 MeV in10 Be, are populated by this one-neutron transfer reaction. These three states in10 Be are clearly discriminated from the -value spectrum, which is rebuilt from energies and angles of the recoil deuterons in coincidence with10 Be. A spectroscopic factor for each state is extracted by comparing the ex.erimental differential cross sections to the theoretical calculation results using the finite range adiabatic distorted wave approximation method with different global nucleon-nucleus potentials. It is found that the newly extracted spectroscopic factors for the 0＋and 2＋states are consistent with the previous ones, but the factor for the multiplet is smaller than the value in the reference, and the possible reason is discussed.

关键词： Be A New Measurement of p,d

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COSMIC RADIATION AND TUBeRCULOSIS Ⅵ. IMMUNIZING PROPeRTY OF TUBeRCLe BACILLI exPOSeD TO COSMIC RADIATION

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Science in China,Ser.A 1964年第2期 259-261页

作者：王善源 Institute of epidemiology and Microbiology Academy of Medical Sciences Peking

It has been shown in a previous paper that tubercle bacilli exposed to cosmic radiation at sea-level with 2.1, 3.2, 4.2, 5.3, 6.3, 7.4, 9.5, and 10.5cm Pb all showed a significantly attenuated virulence as compared with the control, i.e., tubercle bacilli exposed to direct cosmic radiation. The decrease in virulence of tubercle bacilli exposed to cosmic radiation under 2.1, 7.4, and 9.5 cm Pb was especially marked. In fact, 45 mice out of 55 mice injected with these bacilli were still alive 80 days after infection, whereas

关键词： Pb cm COSMIC RADIATION AND TUBeRCULOSIS IMMUNIZING PROPeRTY OF TUBeRCLe BACILLI exPOSeD TO COSMIC RADIATION

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以新工科建设推动材料化工行业毕业生高质量充分就业

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中国大学生就业 2023年第1期 24-29页

作者：巩金龙天津大学党委教育部材料化工行业就业创业指导委员会

人才是材料化工行业发展的根本支撑,直接关乎整个行业未来的发展。培养符合材料化工行业发展的卓越人才,促进毕业生高质量充分就业是高校实现好“四个服务”办学使命的重要体现。准确把握我国材料化工行业发展新趋势、人才需求新情况、... 详细信息

人才是材料化工行业发展的根本支撑,直接关乎整个行业未来的发展。培养符合材料化工行业发展的卓越人才,促进毕业生高质量充分就业是高校实现好“四个服务”办学使命的重要体现。准确把握我国材料化工行业发展新趋势、人才需求新情况、毕业生就业新形势,依托新工科建设,形成材料化工行业卓越工程师培养新模式,是材料化工行业毕业生高质量充分就业的必由之路。

关键词：新工科材料化工行业高质量充分就业

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Discovery of synergistic anti-inflammatory compound combination from herbal formula GuGe FengTong Tablet

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Chinese Journal of Natural Medicines 2018年第9期16卷 683-692页

作者： LIU Le-Le LIU Qun LI Ping LIU e-Hu State Key Laboratory of Natural Medicines School of Traditional Chinese PharmacyChina Pharmaceutical University

Multi-components in herbal formulae exert holistic effects in synergistic or additive manners. However, appropriate strategies and supportive evidences are still lacking to uncover the synergistic or additive combinations. The present investigation aimed at seeking a screening strategy to identify the targeted combinations in GuG e FengT ong Tablet(GGFTT), an herbal formula. Two compounds, belonging to different chemical classes, were combined with different concentration ratios and their anti-inflammation effects were investigated. The most significant anti-inflammatory combinations were evaluated by combination index(CI) method(additive effect, CI = 1; synergism, CI 1). The modulating effects of candidate combinations on pro-inflammatory cytokines and MAPKs signaling pathway were also detected. Two combinations, "biochanin A + 6-gingerol"(Bio-6 G) and "genistein + 6-gingerol"(Gen-6 G), showed synergistic effects(CI elected for further study. Compared with single compound, Bio-6 G could synergistically inhibit the production of pro-inflammatory cytokines(TNF-α, IL-1β, and IL-6) and the activation of MAPKs signaling pathway in LPS-stimulated RAW264.7 cells. The combined results showed that Bio-6 G was a synergistic anti-inflammatory combination in GGFTT. Our results could provide a useful strategy to screen the synergistic combinations in herbal formulae.

关键词： GuGe FengTong Tablet Synergistic combinations Anti-inflammation Cytokines MAPKs

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力学刺激与淫羊藿苷耦合作用抑制疲劳损伤诱导破骨细胞分化的分子机制研究

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国际生物医学工程杂志 2018年第5期41卷 386-389,394页

作者：刘立丽骆雄飞刘斯文赵娜张西正王强松天津中医药大学第一附属医院推拿科 300193 军事科学院系统工程研究院卫勤保障技术研究所天津300161 中国医学科学院北京协和医学院生物医学工程研究所天津300192

目的探讨力学刺激与淫羊藿苷(ICA)耦合作用对疲劳载荷下破骨细胞分化的影响及可能存在的分子机制。方法体外培养小鼠单核巨噬细胞系RAW264.7,空白对照组为α-MeM完全培养基;疲劳载荷下破骨细胞模型组更换为破骨细胞培养液(含质量浓度... 详细信息

目的探讨力学刺激与淫羊藿苷(ICA)耦合作用对疲劳载荷下破骨细胞分化的影响及可能存在的分子机制。方法体外培养小鼠单核巨噬细胞系RAW264.7,空白对照组为α-MeM完全培养基;疲劳载荷下破骨细胞模型组更换为破骨细胞培养液(含质量浓度为40 ng/ml巨噬细胞集落刺激因子和40 ng/ml破骨细胞分化因子的α-MeM完全培养基),并对RAW264.7细胞施加5 000 με基底拉伸应变;力学刺激+ICA组经上述细胞因子和高应变(5 000 με)刺激后,更换为含有1×10^-5 mol/L ICA的α-MeM完全培养基,并施加1 000 με基底拉伸应变。采用抗酒石酸酸性磷酸酶(TRAP)检测试剂盒检测破骨细胞中TRAP的活性变化;实时定量PCR检测破骨细胞标志性基因TRAP、组织蛋白酶K(CTSK)和基质金属蛋白酶9(MMP-9)的mRNA表达;蛋白质印迹法(Western Blot)分析核因子κB(NF-κB)异位情况。结果与模型组相比,力学刺激(1 000 με的基底拉伸)和ICA(1×10^-5 mol/L)耦合作用能显著抑制破骨细胞中TRAP的活性(P<0.01),减少破骨细胞的形成;显著下调标志性基因TRAP、CTSK和MMP-9的mRNA表达,差异均具有统计学意义(均P<0.01);通过抑制NF-κB信号通路中P65、P50、NF-κB抑制蛋白-α(IκB-α)的磷酸化来抑制破骨细胞的生成。结论力学刺激与ICA耦合作用可有效抑制疲劳载荷下破骨细胞的分化及其骨吸收功能,其作用机制可能是通过调节NF-κB信号通路来实现。

关键词：力学刺激淫羊藿苷破骨细胞核因子κB

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Two annular CsI(Tl) detector arrays for the charged particle telescopes

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Nuclear Science and Techniques 2023年第10期34卷 158-165页

作者： Hong-Yu Zhu Jian-Ling Lou Yan-Lin Ye Li-Sheng Yang Bo-Long xia Kang Wei Ying Chen Wei-Liang Pu Zi-Yao Hu Hao-Yu Ge Jia-Hao Chen Kai Ma Wen-Wu Wan Hooi-Jin ong Yan-Yun Yang Shi-Wei xu Kang Wang Fang-Fang Duan Jun-Bin Ma Zhen Bai Peng Ma Ruo-Fu Chen School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking UniversityBeijing 100871China Institute of Modern Physics Chinese Academy SciencesLanzhou 730000China

In this study,we constructed two annular detector arrays comprising 24 wedge-shaped CsI(Tl) crystals,and tested them using anαsource and radioactive beams of ^(14-16) Con a CD_2 *** compared the properties of a CsI(Tl) crystal encapsulated with various reflectors,revealing that using the 80-μm-thick eSR film to pack the CsI(Tl) crystal yielded the largest light output with the smallest non-uniformity in light output (ΔLO).For the 24 CsI(Tl) detectors with the 80-μm-thick eSR films,the average energy resolution improved as the average light output increased;however,it deteriorated as theΔLO value *** form two annular Si-CsI(Tl) telescopes for identifying the light-charged particles,theΔLO value and energy resolution of each CsI(Tl) detector were maintained under 20%and 7.7%,*** telescopes were tested for the first time in a direct nuclear reaction ex.eriment using ^(14-16) C+*** results demonstrated that the Z=1 and Z=2 charged particles were adequately discriminated by the telescopes using the standardΔe-e method.

关键词： Wedge-shaped CsI(Tl)detector Light output non-uniformity Si-CsI(Tl)telescope Particle identification

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Recent advances and applications of deep learning methods in materials science

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npj Computational Materials 2022年第1期8卷 548-573页

作者： Kamal Choudhary Brian DeCost Chi Chen Anubhav Jain Francesca Tavazza Ryan Cohn Cheol Woo Park Alok Choudhary Ankit Agrawal Simon J.L.Billinge elizabeth Holm Shyue Ping ong Chris Wolverton Materials Science and engineering Division National Institute of Standards and TechnologyGaithersburgMD20899USA Theiss Research La JollaCA92037USA DeepMaterials LLC Silver SpringMD20906USA Material Measurement Science Division National Institute of Standards and TechnologyGaithersburgMD20899USA Department of Nanoengineering University of California San DiegoSan DiegoCA92093USA energy Technologies Area Lawrence Berkeley National LaboratoryBerkeleyCAUSA Department of Materials Science and engineering Carnegie Mellon UniversityPittsburghPA15213USA Department of Materials Science and engineering Northwestern UniversityEvanstonIL60208USA Department of electrical and Computer engineering Northwestern UniversityEvanstonIL60208USA Department of Applied Physics and Applied Mathematics and the Data Science Institute Fu Foundation School of Engineering and Applied SciencesColumbia UniversityNew YorkNY10027USA

Deep learning(DL)is one of the fastest-growing topics in materials data science,with rapidly emerging applications spanning atomistic,image-based,spectral,and textual data *** allows analysis of unstructured data and automated identification of *** recent development of large materials databases has fueled the application of DL methods in atomistic prediction in *** contrast,advances in image and spectral data have largely leveraged synthetic data enabled by high-quality forward models as well as by generative unsupervised DL *** this article,we present a high-level overview of deep learning methods followed by a detailed discussion of recent developments of deep learning in atomistic simulation,materials imaging,spectral analysis,and natural language *** each modality we discuss applications involving both theoretical and ex.erimental data,typical modeling approaches with their strengths and limitations,and relevant publicly available software and *** conclude the review with a discussion of recent cross-cutting work related to uncertainty quantification in this field and a brief perspective on limitations,challenges,and potential growth areas for DL methods in materials science.

关键词： learning limitations textual

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基于有效期望质量度量的图像混合丢包保护方法

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西安电子科技大学学报 2006年第5期33卷 696-699,744页

作者：杨亚东吴成柯肖嵩杜建超西安电子科技大学综合业务网理论与关键技术国家重点实验室

针对现有基于交织器结构的不等丢包保护方案通常以端到端期望质量度量系统性能,而没有考虑最小质量要求的问题,提出了以有效期望质量度量系统性能的新判据.有效期望质量定义为扣除传输失败情况后接收端得到的期望质量.基于此新判据,提... 详细信息

针对现有基于交织器结构的不等丢包保护方案通常以端到端期望质量度量系统性能,而没有考虑最小质量要求的问题,提出了以有效期望质量度量系统性能的新判据.有效期望质量定义为扣除传输失败情况后接收端得到的期望质量.基于此新判据,提出了一种双向局部搜索的信源/信道码率分配算法.采用双状态马尔可夫网络模型,通过对SPIHT和JPeG2000编码器产生的码流数据进行仿真实验,结果表明,新算法与基于端到端期望质量度量的原算法相比能显著提高有效期望质量,降低传输失败事件发生的概率,同时计算复杂度也明显减小.

关键词：图像传输联合信源/信道编码不等保护 QoS JPeG2000

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Modular micro-PCR system for the onsite rapid diagnosis of COVID-19

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Microsystems & Nanoengineering 2022年第4期8卷 125-136页

作者： Phuong Quoc Mai Nguyen Ming Wang Nelisha Ann Maria Adelicia Yongling Li Hsih Yin Tan Gordon Minru x.ong Meng-Kwang Marcus Tan Ali Asgar S.Bhagat Catherine W.M.ong Chwee Teck Lim Institute for Health Innovation and Technology(iHealthtech) National University of SingaporeMD614 Medical Drive#14-01Singapore 117599Singapore Department of Biomedical engineering National University of Singapore4 Engineering Drive 3Block 4#04-08Singapore 117583Singapore Advanced MedTech 2 Venture Drive#23-18 Vision ExchangeSingapore 608526Singapore Infectious Diseases Translational Research Programme Department of MedicineYong Loo Lin School of MedicineNational University of SingaporeNUHS Tower Block1E Kent Ridge Road Level 11Singapore 119228Singapore

effective containment of the COVID-19 pandemic requires rapid and accurate detection of the *** chain reaction(PCR)remains the gold standard for COVID-19 *** this article,we report the performance of a cost-effective modular microfluidic reverse transcription(RT)-PCR and RT-loop mediated isothermal amplification(RTLAMP)platform,epidax®,for the point-of-care testing and confirmation of *** platform is versatile and can be reconfigured either for screening using endpoint RT-PCR or RT-LAMP tests or for confirmatory tests using realtime ***®is highly sensitive and detects as little as 1 RNA copy perµL for real-time and endpoint RT-PCR,while using only half of the *** achieved comparable results with those of a commercial platform when detecting SARS-CoV-2 viruses from 81 clinical RNA ***®can also detect SARS-CoV-2 from 44 nasopharyngeal samples without RNA extraction by using a direct RT-PCR assay,which shortens the sample-to-answer time to an hour with minimal user ***,we validated the technology using an RT-LAMP assay on 54 clinical RNA ***,our platform provides a sensitive,cost-effective,and accurate diagnostic solution for lowresource settings.

关键词： fir confirmation diagnosis

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