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Clinical features and treatment outcomes of major depressive disorder with genital symptoms

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Chinese Medical Journal 2024年第5期137卷 622-624页

作者： Xiaohui wu Yuncheng Zhu Ping Sun Shuo Wang zhiguo wu Jia Huang Lan Cao Yun Wang Yousong Su Zhijian Yao Zuowei Wang Fan Wang Yong Wang Daihui Peng Jun Chen Yiru Fang Department of Clinical Research Center&Division of Mood Disorders Shanghai Mental Health CenterShanghai Jiao Tong University School of MedicineShanghai 200030China Department of Mood Disorders Shanghai Hongkou Mental Health CenterShanghai 200083China Department of Psychiatry Nanjing Medical University Affiliated Brain HospitalNanjingJiangsu 210029China Department of Psychiatry&Affective Disorders Center Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China CAS Center for Excellence in Brain Science and Intelligence Technology Shanghai 200031China Shanghai Key Laboratory of Psychotic Disorders Shanghai 200118China

To the Editor:Major depressive disorder(MDD)is a mood disorder characterized by complex patterns of emotional,cognitive,and behavioral symptomology and deficits in daily *** symptoms,including a reduction in libido and menstrual disturbances,have been considered to be a classic symptom of MDD for many *** evidence has reached a broad consensus that the incidence of genital symptoms is higher in patients with MDD than in the general population.A systematic review and meta-analysis found a bidirectional association between MDD and genital symptoms,with patients with MDD showing a 50–70%increased risk of developing genital symptoms,while individuals with genital symptoms had a 130–210%increased risk of developing MDD.^([1])As previously reported,50–70%of people with MDD experience sexual dysfunction.^([2])To date,few studies have focused on the comparison of clinical features between patients with MDD with and without genital symptoms,and the longitudinal prognosis.

关键词： symptoms Clinical features

考虑货运效益、碳排放和道路交通影响的城市公共物流节点选址分析

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管理评论 2024年第9期036卷 206-218页

作者：王艳霞李伊松吴志国北京交通大学经济管理学院北京联合大学城市轨道交通与物流学院

合理的公共物流节点选址是政府制定有效的城市物流节点空间布局规划，推动城市物流高效有序发展的前提。本文从政府角度出发，综合考虑基于城市公共物流节点位置的平均最短行驶时间、最小运输总成本、货运可达性三个方面的货运效益，货... 详细信息

合理的公共物流节点选址是政府制定有效的城市物流节点空间布局规划，推动城市物流高效有序发展的前提。本文从政府角度出发，综合考虑基于城市公共物流节点位置的平均最短行驶时间、最小运输总成本、货运可达性三个方面的货运效益，货运流动产生的碳排放和对道路交通的影响，提出了一个城市公共物流节点选址分析方法。本文将提出的方法应用于北京市，分析了北京市最佳的城市物流节点空间布局方案。研究发现：(1)北京市公共物流节点选址不宜超过距离城市中心40千米，当前布局方案可能会加重京良桥至六里桥之间的京港澳高速、北二环等部分路段的交通拥堵；(2)提高基于公共物流节点的货运可达性是政府提高城市货运效益，减少城市货运带来的碳排放的有效手段。本文提出的方法可以为政府通过制定合理的物流节点布局规划，实现可持续的城市物流发展提供理论支撑。

关键词：公共物流节点选址规划货运可达性碳排放交通拥堵

Influences of deposition parameters on the microstructure and properties of nanostructural TiN films synthesized by filtered cathodic arc plasma

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Rare Metals 2005年第4期24卷 370-375页

作者： ZHANG Yujuan YAN Pengxun wu zhiguo ZHANG Pingyu Laboratory for Special Functional Materials Henan University Kaifeng 475001 China Department of Physics Lanzhou University Lanzhou 730000 China

Titanium nitride （TIN） films with nanostructure were prepared at ambient temperature on a （111） silicon substrate by the filtered cathodic arc plasma （FCAP） technology with an in-plane ＂S＂ filter. The effects of deposition parameters on the grain size, texture and nano-hardness of the films were systematically investigated. The grain size was obtained through calculation using the Scherrer formula and observed by TEM. The results of X-ray diffraction and electron diffraction indicated that increasing either negative substrate bias or argon flow promoted the formation of （111） preferred orientation. High argon flow leads to biaxial texture. The micro-hardness of the TIN films as a function of grain size showed a behavior according to the Hall-Petch relation under high argon flow.

关键词： inorganic nonmetallic materials titanium nitride deposition nanostructure

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苯酚降解复合菌群的构建及其降解动力学

生物学杂志 2024年第3期41卷 98-102页

作者：杨宗政刘伟萌吴志国赵文立天津科技大学化工与材料学院天津300457 天津市卤水化工与资源生态化利用重点实验室天津300457

为提高废水中苯酚的降解效率,利用微生物之间的协同作用将3种菌株进行复配,构建出能有效降解苯酚的复合菌群。首先,通过正交试验优化不同菌株的复配比。随后,探究复合菌群对初始质量浓度范围为400~1 400 mg/L的苯酚的降解过程,并首次提... 详细信息

为提高废水中苯酚的降解效率,利用微生物之间的协同作用将3种菌株进行复配,构建出能有效降解苯酚的复合菌群。首先,通过正交试验优化不同菌株的复配比。随后,探究复合菌群对初始质量浓度范围为400~1 400 mg/L的苯酚的降解过程,并首次提出选用Three-half-order模型描述复合菌群对苯酚降解的动力学。结果表明:相比单株菌,优化复配比后的复合菌群能够将苯酚的去除率提高至99.85%。相比一级动力学模型,Three-half-order模型对不同初始质量浓度苯酚的降解过程的预测更加准确。对苯酚的生物降解过程进行动力学建模,有助于了解苯酚降解过程中苯酚质量浓度变化的规律。

关键词：苯酚生物降解复合菌群动力学污水处理

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基于二维码导引生物罐体AGV抓手设计

机械制造与自动化 2024年第5期53卷 175-179页

作者：吴治国仇隽挺徐辉上海松江开放大学上海201601 浙江工业大学浙江杭州310014

生物罐体AGV是医疗机构在低温冷库无人化存储、转运作业的一款机器人。为了解决机器人运行状态定位精度低、识别能力低、转运周期长和抓手机构繁冗等问题。从控制和结构两方面进行优化设计,设计一款基于激光导航融入二维码导航的AGV抓... 详细信息

生物罐体AGV是医疗机构在低温冷库无人化存储、转运作业的一款机器人。为了解决机器人运行状态定位精度低、识别能力低、转运周期长和抓手机构繁冗等问题。从控制和结构两方面进行优化设计,设计一款基于激光导航融入二维码导航的AGV抓手。控制方面,通过变化矩阵区域归一,使用HMD校准方法校准。定位方式,根据环境变化由激光导航与二维码导航相互切换。结构上,引入ECRS原则、变密度法,运用SolidWorks三维软件完成模型,使用SolidWorks分析单元,在材料和载荷的限定条件下对抓手核心部件进行有限元分析。试验结果表明:该设计缩短了作业周期,提高了抓手抓取精度,机构得到精简,具有良好的经济价值。

关键词： AGV抓手二维码导航三维模型有限元法

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基于潜在剖面分析的心理资本类型和相关生理、生化指标与睡眠质量的关系研究

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世界睡眠医学杂志 2024年第2期11卷 371-373页

作者：杜敏张楠吴志国郑傲山东电力中心医院健康管理中心济南250000

目的:探讨心理资本和相关生理、生化指标与睡眠质量的关系,为确定影响睡眠质量的生理因素、心理因素提供科学依据。方法:选取体检者,采用心理资本问卷、匹兹堡睡眠质量指数收集调查对象的相关信息,采集空腹静脉血,测定相关生理、生化指... 详细信息

目的:探讨心理资本和相关生理、生化指标与睡眠质量的关系,为确定影响睡眠质量的生理因素、心理因素提供科学依据。方法:选取体检者,采用心理资本问卷、匹兹堡睡眠质量指数收集调查对象的相关信息,采集空腹静脉血,测定相关生理、生化指标。数据分析采用潜在剖面分析、方差分析、独立样本t检验等分析方法。结果:睡眠质量差组的体质指数、收缩压、三酰甘油、血尿酸均显著高于对照组(均P0.05)。低心理资本组睡眠质量得分显著高于其他3组,中等偏高心理资本组与高心理资本组的睡眠质量得分差异不显著(P>0.05),但2组得分均低于中等偏低心理资本组、低心理资本组。结论:心理资本、体质指数、血压、血脂、尿酸是影响睡眠质量的因素。

关键词：睡眠质量济南市心理资本生化指标潜在剖面分析

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Improving the Thermal Stability of Cu_3N Films by Addition of Mn

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Journal of Materials Science & Technology 2015年第8期31卷 822-827页

作者： Xiaoyan Fan Zhenjiang Li Alan Meng Chun Li zhiguo wu Pengxun Yan Advanced Optoelectronic Materials and Technologies Engineering Laboratory of Qingdao School of Mathematics and PhysicsQingdao University of Science and Technology Key Laboratory of Polymer Material Advanced Manufacturing Technology of Shandong Province Qingdao University of Science and Technology College of Chemistry and Molecular Engineering Qingdao University of Science and Technology Department of Physics Ocean University of China School of Physical Science and Technology Lanzhou University

Mn-doped Cu3N films were deposited by cylindrical magnetron sputtering equipment on the common glass at room temperature. The incorporation of Mn can change the preferred growth orientation from Cu-rich plane （111） to N-rich plane （100） due to the improvement of nitridation of Cu. The shrinkage of the lattice and the X-ray photoelectron spectroscopy results reveal that Mn should replace Cu atoms in the lattice or be segregated in the grain boundaries. The thickness of Mn-doped film is smaller than that of the pure one due to the less physisorption of N species among the columnar grains. The mean grain size and the energy gap become larger with increasing Mn concentration to 2.2 at.% and then decrease when the concentration of Mn is higher than 2.2 at.%. Notably, weak doping of 1.5 at.% Mn successfully promotes the decomposed temperature by -50℃. According to the results of XRD and SEM for Mn- doped films annealed in vacuum, a possible decomposed mechanism with increasing the annealing temperature is proposed.

关键词： Magnetron sputtering Cu3N film Mn-doped Thermal stability

开放大学基层分校理工专业在线实践教学模式的应用研究

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湖北开放大学学报 2024年第2期44卷 30-35页

作者：王芳徐辉吴治国赵鹏程上海科创职业技术学院上海201600 上海松江开放大学上海201600

随着信息技术的不断发展,开放大学基层分校理工专业积极尝试在线实践教学模式的应用研究。通过观察、问卷访谈以及大量实践,提出了开放大学提高在线实践教学模式成效的三大途径,包括:加强虚拟仿真实验平台建设或引入云服务器技术、开展... 详细信息

随着信息技术的不断发展,开放大学基层分校理工专业积极尝试在线实践教学模式的应用研究。通过观察、问卷访谈以及大量实践,提出了开放大学提高在线实践教学模式成效的三大途径,包括:加强虚拟仿真实验平台建设或引入云服务器技术、开展课程在线实践教学案例设计以及设计合理的在线课程实践评价指标体系。

关键词：在线实践教学开放教育 STEAM 虚拟仿真实验平台云服务器技术

Large-scale long terminal repeat insertions produced a significant set of novel transcripts in cotton

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Science China(Life Sciences) 2023年第8期66卷 1711-1724页

作者： Yan Yang Xingpeng Wen zhiguo wu Kun Wang Yuxian Zhu Institute for Advanced Studies Wuhan UniversityWuhan 430072China College of Life Sciences Wuhan UniversityWuhan 430072China Hubei Hongshan Laboratory Wuhan 430072China TaiKang Center for Life and Medical Sciences RNA InstituteRemin HospitalWuhan UniversityWuhan 430072China

Genomic analysis has revealed that the 1,637-Mb Gossypium arboreum genome contains approximately 81%transposable elements(TEs),while only 57%of the 735-Mb *** genome is occupied by *** this study,we investigated whether there were unknown transcripts associated with TE or TE fragments and,if so,how these new transcripts were evolved and *** sequence depths increased from 4 to 100 G,a total of 10,284 novel intergenic transcripts(intergenic genes)were *** average,approximately 84%of these intergenic transcripts possibly overlapped with the long terminal repeat(LTR)insertions in the otherwise untranscribed intergenic regions and were expressed at relatively low *** of these intergenic transcripts possessed no transcription activation markers,while the majority of the regular genic genes possessed at least one such *** without transcription activation markers formed their+1 and-1 nucleosomes more closely(only(117±1.4)bp apart),while twice as big spaces(approximately(403.5±46.0)bp apart)were detected for genes with the activation *** analysis of 183 previously assembled genomes across three different kingdoms demonstrated systematically that intergenic transcript numbers in a given genome correlated positively with its LTR *** analysis revealed that genic genes originated during one of the whole-genome duplication events around 137.7million years ago(MYA)for all eudicot genomes or 13.7 MYA for the Gossypium family,respectively,while the intergenic transcripts evolved around 1.6 MYA,resultant of the last LTR *** characterization of these low-transcribed intergenic transcripts can facilitate our understanding of the potential biological roles played by LTRs during speciation and diversifications.

关键词： RNA-seq intergenic transcripts long terminal repeat epigenetic modification nucleosomes