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Process metallurgy and data-driven prediction and feedback of blast furnace heat indicators

International Journal of Minerals,Metallurgy and Materials 2024年第6期31卷 1228-1240页

作者： Quan Shi Jue Tang Mansheng chu School of Metallurgy Northeastern UniversityShenyang 110819China Institute for Frontier Technologies of Low-carbon Steelmaking Northeastern UniversityShenyang 110819China Engineering Research center of Frontier Technologies for Low-carbon Steelmaking(Ministry of Education) Shenyang 110819China

The prediction and control of furnace heat indicators are of great importance for improving the heat levels and conditions of the complex and difficult-to-operate hour-class delay blast furnace(BF)*** this work,a prediction and feedback model of furnace heat indicators based on the fusion of data-driven and BF ironmaking processes was *** data on raw and fuel materials,process op-eration,smelting state,and slag and iron discharge during the whole BF process comprised 171 variables with 9223 groups of data and were comprehensively analyzed.A novel method for the delay analysis of furnace heat indicators was *** extracted delay variables were found to play an important role in *** method that combined the genetic algorithm and stacking efficiently im-proved performance compared with the traditional machine learning algorithm in improving the hit ratio of the furnace heat prediction *** hit ratio for predicting the temperature of hot metal in the error range of±10℃ was 92.4%,and that for the chemical heat of hot metal in the error range of±0.1wt%was 93.3%.On the basis of the furnace heat prediction model and expert experience,a feedback model of furnace heat operation was established to obtain quantitative operation suggestions for stabilizing BF heat *** sugges-tions were highly accepted by BF ***,the comprehensive and dynamic model proposed in this work was successfully ap-plied in a practical BF *** improved the BF temperature level remarkably,increasing the furnace temperature stability rate from 54.9%to 84.9%.This improvement achieved considerable economic benefits.

关键词： blast furnace furnace heat genetic algorithm stacking prediction and feedback

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MOF-derived porous graphitic carbon with optimized plateau capacity and rate capability for high performance lithium-ion capacitors

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International Journal of Minerals,Metallurgy and Materials 2024年第2期31卷 395-404页

作者： Ge chu chaohui wang Zhewei Yang Lin Qin Xin Fan college of Materials Science&Engineering Guilin University of TechnologyGuilin 541004China Institute of Energy Innovation College of Materials Science and EngineeringTaiyuan University of TechnologyTaiyuan 030024China

The development of anode materials with high rate capability and long charge-discharge plateau is the key to improve per-formance of lithium-ion capacitors(LIcs).Herein,the porous graphitic carbon(PGc-1300)derived from a new triply interpenetrated co-balt metal-organic framework(co-MOF)was prepared through the facile and robust carbonization at 1300°c and washing by Hcl *** as-prepared PGc-1300 featured an optimized graphitization degree and porous framework,which not only contributes to high plateau capacity(105.0 mAh·g^(−1)below 0.2 V at 0.05 A·g^(−1)),but also supplies more convenient pathways for ions and increases the rate capability(128.5 mAh·g^(−1)at 3.2 A·g^(−1)).According to the kinetics analyses,it can be found that diffusion regulated surface induced capa-citive process and Li-ions intercalation process are coexisted for lithium-ion ***,LIc PGc-1300//Ac constructed with pre-lithiated PGc-1300 anode and activated carbon(Ac)cathode exhibited an increased energy density of 102.8 wh·kg^(−1),a power dens-ity of 6017.1 w·kg^(−1),together with the excellent cyclic stability(91.6%retention after 10000 cycles at 1.0 A·g^(−1)).

关键词： metal-organic framework porous graphitic carbon optimized plateau capacity kinetic analysis lithium-ion capacitor

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Developing risk models and subtypes of autophagy-associated LncRNAs for enhanced prognostic prediction and precision in therapeutic approaches for liver cancer patients

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Oncology Research 2024年第4期32卷 703-716页

作者： LU ZHANG JINGUO chu YUSHAN YU Department of General Practice The First Affiliated Hospital of Ningbo UniversityNingboChina

Background:Limited research has been conducted on the influence of autophagy-associated long non-coding RNAs(ARLncRNAs)on the prognosis of hepatocellular carcinoma(Hcc).Methods:we analyzed 371 Hcc samples from TcGA,identifying expression networks of ARLncRNAs using autophagy-related *** for prognostically relevant ARLncRNAs involved univariate cox regression,Lasso regression,and multivariate cox regression.A Nomogram was further employed to assess the reliability of Riskscore,calculated from the signatures of screened ARLncRNAs,in predicting ***,we compared drug sensitivities in patient groups with differing risk levels and investigated potential biological pathways through enrichment analysis,using consensus clustering to identify subgroups related to ***:The screening process identified 27 ARLncRNAs,with 13 being associated with Hcc ***,a set of signatures comprising 8 ARLncRNAs was successfully constructed as independent prognostic factors for *** in the high-risk group showed very poor prognoses in most clinical *** Riskscore was closely related to immune cell scores,such as macrophages,and the DEGs between different groups were implicated in metabolism,cell cycle,and mitotic ***,high-risk group patients demonstrated a significantly lower Ic50 for Paclitaxel,suggesting that Paclitaxel could be an ideal treatment for those at elevated risk for *** further identified c2 as the Paclitaxel subtype,where patients exhibited higher Riskscores,reduced survival rates,and more severe clinical ***:The 8 signatures based on ARLncRNAs present novel targets for prognostic prediction in *** drug candidate Paclitaxel may effectively treat Hcc by impacting ARLncRNAs *** the identification of ARLncRNAsrelated isoforms,these results provide valuable insights for clinical exploration of autophagy mechanisms in Hcc pathogenesis and offer potential av

关键词： Autophagy Hepatocellular carcinoma(Hcc) Prognosis Precision medicine Paclitaxel

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脑卒中伴融合型脑白质病变患者的他汀类药物治疗

脑卒中伴融合型脑白质病变患者的他汀类药物治疗

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2013年全国老年性痴呆与相关疾病学术会议

作者：熊云云 Adrian wong Margherita cavalieri Reinhold Schmidt winnie w.c.chu Ka Sing wong 刘新峰 Vincent Mok 南京军区南京总医院神经内科香港中文大学药物与治疗学系香港教育学院心理学研究部心理健康和老龄化中心

目的:脑白质病变(white matter hyperintensity,wMH)和腔隙性脑梗死是两种脑小血管病。他汀类药物可降低各类脑卒中的复发率,其中包括腔隙性脑梗死。本文旨在研究他汀类药物对脑卒中伴融合型wMH的患者是否存在延缓wMH进展和/或认知功能...

目的:脑白质病变(white matter hyperintensity,wMH)和腔隙性脑梗死是两种脑小血管病。他汀类药物可降低各类脑卒中的复发率,其中包括腔隙性脑梗死。本文旨在研究他汀类药物对脑卒中伴融合型wMH的患者是否存在延缓wMH进展和/或认知功能障碍的作用。方法:研究入组了100例基线MRI上存在融合型wMH的患者,其中81例完成了2年随访。使用MMSE和MDRS I/P量表分别评估总体认知功能和执行功能。比较他汀治疗组和非他汀治疗组wMH体积和认知的变化,同时评估他汀类药物对新发脑梗死灶和新发微出血发生率的影响。结果:他汀治疗组(50例)较非他汀治疗组(31例)的wMH体积进展慢(1.54±4.52cm VS 5.01±6.00 cm,P=0.01)。他汀类药物的使用是wMH体积进展的独立预测因子(β=-0.322,P=-0.010),并与MDRS I/P评分呈正相关(β=0.474,P=0.001),而与MMSE变化无相关性,与新发脑梗死灶和新发微出血无相关性。结论:对于脑卒中伴融合型白质病变的患者,他汀类药物可减缓wMH的进展以及执行功能的下降。

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Lipocoacervate,a tunable vesicle for protein delivery

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Nano Research 2024年第10期17卷 9135-9140页

作者： chia-wei Yeh Nathaniel wright chelsea Loh Nabeen chu Yadong wang Nancy E.and Peter c.Meinig School of Biomedical Engineering Cornell UniversityKimball Hall 290Ithaca 14853USA Human Biology Healthand Society.College of Human EcologyCornell UniversityIthaca 14853USA

controlled delivery of proteins and other biologics is a growing medium of therapy for diseases previously *** we report a self-assembling,tunable vesicle for the controlled delivery of growth factors and *** made of heparin and a biocompatible polycation,PEAD,forms the core of the vesicle;lipids form the membrane of the *** call this vesicle lipocoacervate(Lipco),which has a high affinity for growth factors and cytokines due to *** is a tunable protein delivery *** vesicle size is controlled through polymer and salt *** functionalization enables potential for targeting capabilities with long-term storage through ***,the controlled delivery of therapeutics also avoids high toxicity to treated cells in *** we report on these key principles of Lipco assembly and design.

关键词： complex coacervate drug delivery protein delivery heparin lipid particle

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香港儿童服用低剂量三聚氰胺后肾脏并发症的现况调查研究

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英国医学杂志中文版 2009年第3期12卷 145-148页

作者： Hugh S Lam Pak c Ng winnie c w chu william wong Dorothy F Y chan Stella S Ho Ka T wong Anil T Ahuja chi K Li 张宁(译) 杨勇(校) Department of Paediatrics The Chinese University of Hong Kong Department of Diagnostic Radiology and Organ Imaging The Chinese University of Hong Kong 首都医科大学北京朝阳医院泌尿外科

目的调查香港儿童服用小剂量三聚氰胺后的肾脏并发症。设计横断面调查方法。机构香港专业评估中心。调查对象根据全港初级医疗保健中心的记录，研究包括3170例（1748例男童，1422例女童）≤12岁、连续1个月或以上服用被三聚氰胺污... 详细信息

目的调查香港儿童服用小剂量三聚氰胺后的肾脏并发症。设计横断面调查方法。机构香港专业评估中心。调查对象根据全港初级医疗保健中心的记录，研究包括3170例（1748例男童，1422例女童）≤12岁、连续1个月或以上服用被三聚氰胺污染奶制品的儿童。主要评估指标是否存在肾结石和血尿。结果 1例儿童存在肾结石，7例儿童肾脏内可疑存在三聚氰胺结晶，应用尿试纸检查发现208例（6．6％）儿童存在血尿。这些儿童在专业评估中心进一步检查后，仅有7．4％的儿童确实存在显微镜下血尿，所以总体儿童血尿出现率低于1％。结论：在曾服用小剂量三聚氰胺的儿童中，没有急性肾功能衰竭或尿路梗阻等严重不良事件发生。我们的研究结果与全港调查一致。即使将7例肾内可疑存在三聚氰胺结晶的患儿包括在内，应用超声检查发现的可疑三聚氰胺相关不良事件发生率也仅为0．2％，且这些患儿尚不需要进一步治疗。应用尿试纸检测是否存在血尿，可能会过高估计血尿的发生率。研究结果提示对于曾服用小剂量三聚氰胺的儿童进行大范围、积极的检查可能并不会得到更多有意义的资料，所以不值得投入更多的经费去进行这种检查。

关键词：肾脏并发症儿童氰胺三聚服用香港低剂量镜下血尿

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Alterations of soil aggregates and intra-aggregate organic carbon fractions after soil conversion from paddy soils to upland soils:Distribution,mineralization and driving mechanism

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Pedosphere 2024年第1期34卷 121-135页

作者： Longfei KANG Jiamei wU chunfeng ZHANG Baoguo ZHU Guixin chu college of Life Science Shaoxing UniversityShaoxing 312000China The Key Laboratory of Oasis Eco-agriculture Xinjiang Production and Construction Group/Department of Resources and Environmental SciencesAgronomy CollegeShihezi UniversityShihezi 832000China Hunan Institute of Agricultural Environment and Ecology Changsha 410000China Jiamusi Branch Heilongjiang Academy of Agricultural SciencesJiamusi 154007China

Investigating the impacts of soil conversion on soil organic carbon(Oc) content and its fractions within soil aggregates is essential for defining better strategies to improve soil structure and Oc sequestration in terrestrial ecosystems. However, the consequences of soil conversion from paddy soil to upland soil for soil aggregates and intra-aggregate Oc pools are poorly understood. Therefore, the objective of this study was to quantify the effects of soil conversion on soil aggregate and intra-aggregate Oc pool distributions. Four typical rice-producing areas were chosen in North and South china, paired soil samples(upland soil converted from paddy soil more than ten years ago vs. adjacent paddy soil) were collected(0–20 cm) with three replicates in each area. A set of core parameters(Oc preservation capacity, aggregate carbon(c) turnover, and biological activity index) were evaluated to assess the responses of intra-aggregate Oc turnover to soil conversion. Results showed that soil conversion from paddy soil to upland soil significantly improved the formation of macro-aggregates and increased aggregate stability. It also notably decreased soil intra-aggregate Oc pools, including easily oxidized Oca(EOca), particulate Oca(POca), and mineral-bound(MOca) Oc, and the sensitivity of aggregate-associated Oc pools to soil conversion followed the order: EOca(average reduction of 21.1%) > MOca(average reduction of 15.4%) > POca(average reduction of 14.8%). The potentially mineralizable c(c_(0)) was significantly higher in upland soil than in paddy soil, but the corresponding decay constant(k) was lower in upland soil than in paddy soil. Random forest model and partial correlation analysis showed that EOca and pH were the important nutrient and physicochemical factors impacting k of c mineralization in paddy soil,while MOca and c-related enzyme(β-D-cellobiohydrolase) were identified as the key factors in upland soil. In conclusion, this study evidenced that soil conversion

关键词： decay constant easily oxidized organic c macro-aggregate meso-aggregate micro-aggregate mineral-bound organic c particulate organic c potentially mineralizable c

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Recent Advances in Photochemical/Electrochemical carboxylation of Olefins with cO_(2)

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chinese Journal of chemistry 2024年第18期42卷 2249-2266页

作者： Qian wang Yanwei wang Min Liu Ganghui chu Youai Qiu Xinjiang Laboratory of Native Medicinal and Edible Plant Resources chemistry College of Chemistry and Environmental ScienceKashiUniversityKashiXinjiang844000China state Key Laboratory and Institute of Elemento-Organic chemistry Frontiers Science Centerfor New Organic MatterCollege of Chemistry NankaiUniversity94WeijinRoadTianjin300071China

cO_(2) is an abundant,nontoxic,and renewable c1 feedstock in synthetic *** carboxylation of readily available olefins incorporating cO_(2) is regarded as a promising strategy to access high value-added carboxylic acids as well as cO_(2) ***,due to the thermodynamic stability and kinetic inertness of cO_(2) and the difficulty in controlling the regioselectivity,the carboxylation of olefins with cO_(2) still remains ***-type functionalization with olefins represented a powerful protocol and enabled the development of novel transformations in this *** recently,the advance of new technology,such as photoredox catalysis and the renaissance of electrochemistry in organic synthesis,offered access to unique chemical reactivities of radical precursors and provided new solutions to the functionalization of olefins.

关键词： cO_(2) carboxylation Olefins Photocatalysis Electrocatalysis Radical Reduction Difunctionalization

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Glycine-β-cyclodextrin-assisted cometabolism of phenanthrene and pyrene by Pseudomonas stutzeri DJP 1 from marine sediment

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Journal of Oceanology and Limnology 2024年第2期42卷 560-569页

作者： Junfeng JIANG weijun TIAN Zhiyang LU Meile chu Huimin cAO Dantong ZHANG college of Environmental Science and Engineering Ocean University of ChinaQingdao 266100China Key Laboratory of Marine Environment and Ecology Ministry of EducationQingdao 266100China

cometabolic degradation is currently an effective and extensively way to remove high molecular weight polycyclic aromatic hydrocarbons(HMw-PAHs).Unfortunately,due to low bio-accessibility and high biotoxicity,the cometabolic degradation rate of HMw-PAHs is ***-β-cyclodextrin(GcD)was obtained through amino modification ofβ-cyclodextrin(BcD)and added to cometabolic system of phenanthrene(PHE)and pyrene(PYR)to assist PYR *** show that the addition of GcD(100 mg/L)effectively improved the removal rate of PYR(20 mg/L)by 42.3%.GcD appeared to increase the bio-accessibility and reduce the biotoxicity of PHE and PYR,and then promoted the growth of Pseudomonas stutzeri DJP1 and stimulated the elevation of dehydrogenase(DHA)and catechol 12 dioxygenase(c12O)*** phthalate metabolic pathway was accelerated,which improved the cometabolic *** study provided a new reference for the cometabolic degradation of HMw-PAHs.

关键词： cometabolism phenanthrene pyrene glycine-β-cyclodextrin biological accessibility biotoxicity

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Fusion of Ground-Based and Spaceborne Radar Precipitation Based on Spatial Domain Regularization

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Journal of Meteorological Research 2024年第2期38卷 285-302页

作者： Anfan HUANG Leilei KOU Yanzhi LIANG Ying MAO Haiyang GAO Zhigang chu School of Atmospheric Physics Nanjing University of Information Science&TechnologyNanjing 210044 collaborative Innovation center on Forecast and Evaluation of Meteorological Disasters Nanjing University of Information Science&TechnologyNanjing 210044

High-quality and accurate precipitation estimations can be obtained by integrating precipitation information measures using ground-based and spaceborne radars in the same target *** the true precipitation state is a typical inverse problem for a given set of noisy radar precipitation *** regularization method can appropriately constrain the inverse problem to obtain a unique and stable *** different types of precipitation with different prior distributions,the L_(1) and L_(2) norms were more effective in constraining stratiform and convective precipitation,*** a combination of L_(1) and L_(2) norms,the Huber norm is more suitable for mixed precipitation *** study uses different regularization norms to combine precipitation data from the c-band dual-polarization ground radar(cDP)and dual-frequency precipitation radar(DPR)on the Global Precipitation Measurement(GPM)mission core *** to single-source radar data,the fused figures contain more information and present a comprehensive precipitation structure encompassing the reflectivity and precipitation *** 27 precipitation cases,the fusion results utilizing the Huber norm achieved a structural similarity index measure(SSIM)and a peak signal-to-noise ratio(PSNR)of 0.8378 and 30.9322,respectively,compared with the cDP *** fusion results showed that the Huber norm effectively amalgamate the features of convective and stratiform precipitation,with a reduction in the mean absolute error(MAE;16.1%and 22.6%,respectively)and root-mean-square error(RMSE;11.7%and 13.6%,respectively)compared to the 1-norm and ***,in contrast to the fusion results of scale recursive estimation(SRE),the Huber norm exhibits superior capability in capturing the localized precipitation intensity and reconstructing the detailed features of precipitation.

关键词： dual-frequency precipitation radar(DPR) dual-polarization radar data fusion regularization Huber norm

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