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苦丁茶米酒的发酵工艺条件优化

中国酿造 2023年第2期42卷 205-209页

作者：王芙蓉赵益梅李靖唐佳代黄丽姗曹文涛茅台学院酿酒工程系贵州遵义564500 仁怀市中等职业学校贵州遵义564500

以贵州本地特产苦丁茶和大米为原料制备苦丁茶米酒,通过单因素试验、响应面试验优化其发酵工艺条件。结果表明,苦丁茶米酒最佳发酵工艺条件为料液比1.0∶0.8(g∶mL)、酒曲添加量0.6%、发酵时间98 h、发酵温度30℃。在此优化条件下,苦丁... 详细信息

以贵州本地特产苦丁茶和大米为原料制备苦丁茶米酒,通过单因素试验、响应面试验优化其发酵工艺条件。结果表明,苦丁茶米酒最佳发酵工艺条件为料液比1.0∶0.8(g∶mL)、酒曲添加量0.6%、发酵时间98 h、发酵温度30℃。在此优化条件下,苦丁茶米酒酒精度为7.1%vol,茶多酚含量0.87 mg/mL,糖度为19.7°Bx,感官评分89.7分,酒质呈淡绿色,色泽透明,甜度适中,富含茶多酚,入口有米酒香味,后味伴随着苦丁茶的香气,口感协调,产品理化及微生物指标符合国标GB 2758—2012《发酵酒及其配制酒》要求。

关键词：苦丁茶米酒发酵工艺响应面优化

Multidimensional linear cryptanalysis with key difference invariant bias for block ciphers

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Cybersecurity 2021年第1期4卷 501-518页

作者： Wenqin cao wentao Zhang State Key Laboratory of Information Security Institute of Information EngineeringChinese Academy of SciencesNo.89 Minzhuang RoadHaidian District100093 BeijingChina School of Cyber Security University of Chinese Academy of SciencesNo.19 Yuquan RoadShijingshan District100049 BeijingChina School of Mathematics and Statistics Shandong University of TechnologyNo.266Xincunxi RoadZhangdian District255000 ZiboShandongChina

For block ciphers,Bogdanov et *** that there are some linear approximations satisfying that their biases are deterministically invariant under key *** property is called key difference invariant *** on this property,Bogdanov et *** a related-key statistical distinguisher and turned it into key-recovery attacks on LBlock and *** this paper,we propose a new related-key model by combining multidimensional linear cryptanalysis with key difference invariant *** main theoretical advantage is that our new model does not depend on statistical independence of linear *** demonstrate our cryptanalysis technique by performing key recovery attacks on LBlock and *** using the relations of the involved round keys to reduce the number of guessed subkey ***,the partial-compression technique is used to reduce the time *** can recover the master key of LBlock up to 25 rounds with about 260.4 distinct known plaintexts,278.85 time complexity and 261 bytes of memory *** attack can recover the master key of TWINE-128 up to 28 rounds with about 261.5 distinct known plaintexts,2126.15 time complexity and 261 bytes of memory *** results are the currently best ones on cryptanalysis of LBlock and TWINE-128.

关键词： Key-alternating cipher Key difference invariant bias Multidimensional linear cryptanalysis LBlock TWINE

Unraveling post-growth mechanisms of monolayer CsPbBr3 nanocubes:Laser-enhanced transformations and cathodoluminescence-electron microscopy correlations

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Journal of Energy Chemistry 2025年第1期100卷 146-156页

作者： Mingxing Li Xiaoge Wang Xiaofan cao Zhiqun He Chunjun Liang Mingxing Chen Jing Ju Fangtian You Key Laboratory of Luminescence and Optical Information Ministry of Education Institute of Optoelectronic Technology Beijing Jiaotong University Beijing National Laboratory for Molecular Sciences (BNLMS) College of Chemistry and Molecular Engineering Peking University

Lead-halide perovskite nanoparticles（LHP NPs） are highly promising materials for next-generation displays and solid-state lighting due to their exceptional optical properties. However, their inherent instability presents a significant challenge. Recent advances have demonstrated that optoelectronic devices based on monolayer nanoparticle films exhibit both high luminescence efficiency and long-term *** research demonstrates that mobility limitations and anisotropic alignments in CsPbBr3nanocube monolayer films are key to their stabilization, hindering spontaneous growth through face-to-face fusion and resulting in the formation of connecting necks in a diagonal direction. Introducing laser irradiation confirmed this by significantly accelerating nanocubes growth, increasing mobility, and enhancing local structural ordering, leading to larger and more regularly shaped nanosheets. Fourier transform infrared spectroscopy and energy dispersive spectroscopy line-scan analyses indicated that laser irradiation did not disrupt the ligand structure. Transmission electron microscopy and correlative cathodoluminescence electron microscopy revealed the effects of post-growth and heterogeneous structures, including enhanced luminescence and inhomogeneous intensity in the nanosheets. These findings deepen the understanding of the post-growth mechanism of monolayer nanoparticles and the structure-emission correlation and highlight the unique role of laser irradiation in directing the formation of well-defined and regular nanostructures.

关键词： Energy dispersive spectroscopy

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多尺度地理空间要素非一致性检测技术研究

地理空间信息 2020年第8期18卷 94-97,I0003页

作者：曹文涛郭明武贾小霞鲍龙武汉市测绘研究院湖北武汉430022

以线和面要素为例,基于多指标综合加权实现了要素最优组合匹配,在剔除了比例尺表达差异影响情况下,根据非一致性评价类型条件进行实验数据的自动化检测与评价,当选取合理的参数阈值时,验证了非一致性检测的可用性与正确性,大大提高了工... 详细信息

以线和面要素为例,基于多指标综合加权实现了要素最优组合匹配,在剔除了比例尺表达差异影响情况下,根据非一致性评价类型条件进行实验数据的自动化检测与评价,当选取合理的参数阈值时,验证了非一致性检测的可用性与正确性,大大提高了工作效率,有利于提高地理空间数据的应用价值。

关键词：多尺度最优匹配组合非一致性检测

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7×7交互捻钢丝绳拉伸特性的研究

橡胶科技 2022年第8期20卷 378-381页

作者：姚利丽周洁曹文涛江苏兴达钢帘线股份有限公司江苏泰州225721 江苏省结构与功能金属复合材料重点实验室江苏泰州225721

通过有限元模拟与力学试验相结合的方法分析了4种不同捻距配置的7×7Φ3.0 mm交互捻钢丝绳的拉伸特性。结果表明,在轴向拉伸载荷下,捻距对钢丝绳的应力分布有很大的影响,捻距越小,应力越大。试验结果与模拟结果的一致性说明所选用的计... 详细信息

通过有限元模拟与力学试验相结合的方法分析了4种不同捻距配置的7×7Φ3.0 mm交互捻钢丝绳的拉伸特性。结果表明,在轴向拉伸载荷下,捻距对钢丝绳的应力分布有很大的影响,捻距越小,应力越大。试验结果与模拟结果的一致性说明所选用的计算模型是合理的,同时得到了提高钢丝绳破断力的有效方法,可为下一步钢丝绳结构设计研究提供理论指导。

关键词：钢丝绳拉伸捻距应力有限元破断力

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改性沥青再生混合料疲劳抗裂性能评价

低温建筑技术 2020年第3期42卷 29-32页

作者：曹文涛郑俊秋姜严旭江苏交通控股有限公司南京210002 东南大学南京210096

文中基于再生沥青胶结料和再生混合料两个尺度,分别采用动态流变剪切试验(DSR)和弯曲梁流变试验(BBR)评价再生沥青的中低温性能,采用间接拉伸试验(IDT)和小梁弯曲疲劳试验评价再生混合料的疲劳抗裂性能。试验结果表明,再生改性沥青的中... 详细信息

文中基于再生沥青胶结料和再生混合料两个尺度,分别采用动态流变剪切试验(DSR)和弯曲梁流变试验(BBR)评价再生沥青的中低温性能,采用间接拉伸试验(IDT)和小梁弯曲疲劳试验评价再生混合料的疲劳抗裂性能。试验结果表明,再生改性沥青的中温疲劳性能变差,低温劲度变大,并且应力松弛能力下降。IDT试验结果表明,随着再生混合料中RAP掺量的增加,其抗拉强度与弹性模量增加,极限拉应变与韧性指数减小。疲劳试验结果表明,全新料的疲劳性能明显优于再生混合料,再生胶结料的疲劳因子能够很好地反映出再生混合的疲劳抗裂性能,并且施工工艺显著影响着再生混合料的疲劳性能。

关键词：改性沥青流变性能再生混合料疲劳性能抗裂性能

国家新型基础测绘建设武汉试点中期实践与思考

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测绘通报 2022年第1期 164-167页

作者：肖建华李鹏鹏李海亭陈凯曹文涛陈涛武汉市规划编制研究和展示中心湖北武汉430010 武汉市测绘研究院湖北武汉430022

2019年1月武汉正式成为自然资源部批复的首个国家新型基础测绘建设试点城市。经过两年的探索建设,武汉试点紧紧围绕目标任务,开展基础地理数据库的实体化改造升级,在产品体系、技术体系、组织管理体系及标准体系的转型升级方面初步形成... 详细信息

2019年1月武汉正式成为自然资源部批复的首个国家新型基础测绘建设试点城市。经过两年的探索建设,武汉试点紧紧围绕目标任务,开展基础地理数据库的实体化改造升级,在产品体系、技术体系、组织管理体系及标准体系的转型升级方面初步形成了可在全国推广借鉴的阶段性成果。随着试点建设的不断深入,各地、各单位关于新型基础测绘的思想认识也在逐步提升,一些关键问题和难点仍需要在下一阶段的建设工作中深度思考、共同攻关、形成共识,从而高质量推进国家新型基础测绘体系的全面建设。

关键词：国家新型基础测绘武汉试点中期地理实体

Gut microbiota-astrocyte axis: new insights into age-related cognitive decline

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Neural Regeneration Research 2025年第4期20卷 990-1008页

作者： Lan Zhang Jingge Wei Xilei Liu Dai Li Xiaoqi Pang Fanglian Chen Hailong cao Ping Lei Haihe Laboratory of Cell Ecosystem Department of GeriatricsTianjin Medical University General HospitalTianjinChina Tianjin Geriatrics Institute Tianjin Medical University General HospitalTianjinChina Department of Gastroenterology and Hepatology Tianjin Medical University General HospitalNational Key Clinical SpecialtyTianjin Institute of Digestive DiseasesTianjin Key Laboratory of Digestive DiseasesTianjinChina Department of Urology Tianjin Medical University General HospitalTianjinChina Tianjin Neurological Institution Tianjin Medical University General HospitalTianjinChina

With the rapidly aging human population,age-related cognitive decline and dementia are becoming increasingly prevalent *** is considered the main risk factor for cognitive decline and acts through alterations in the composition of the gut microbiota,microbial metabolites,and the functions of *** microbiota–gut–brain axis has been the focus of multiple studies and is closely associated with cognitive *** article provides a comprehensive review of the specific changes that occur in the composition of the gut microbiota and microbial metabolites in older individuals and discusses how the aging of astrocytes and reactive astrocytosis are closely related to age-related cognitive decline and neurodegenerative *** article also summarizes the gut microbiota components that affect astrocyte function,mainly through the vagus nerve,immune responses,circadian rhythms,and microbial ***,this article summarizes the mechanism by which the gut microbiota–astrocyte axis plays a role in Alzheimer’s and Parkinson’s *** findings have revealed the critical role of the microbiota–astrocyte axis in age-related cognitive decline,aiding in a deeper understanding of potential gut microbiome-based adjuvant therapy strategies for this condition.

关键词： age aging Alzheimer’s disease astrocytes cognitive decline dementia gut microbiota gut–brain axis microbial metabolites neuroinflammation Parkinson’s disease

Enhancing m^(6)A modification in the motor cortex facilitates corticospinal tract remodeling after spinal cord injury

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Neural Regeneration Research 2025年第6期20卷 1749-1763页

作者： Tian Qin Yuxin Jin Yiming Qin Feifei Yuan Hongbin Lu Jianzhong Hu Yong cao Chengjun Li Department of Spine Surgery and Orthopedics Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Key Laboratory of Organ Injury Aging and Regenerative Medicine of Hunan ProvinceChangshaHunan ProvinceChina National Clinical Research Center for Geriatric Disorders Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina Department of Sports Medicine Xiangya HospitalCentral South UniversityChangshaHunan ProvinceChina

Spinal cord injury typically causes corticospinal tract disruption. Although the disrupted corticospinal tract can self-regenerate to a certain degree, the underlying mechanism of this process is still unclear. N6-methyladenosine(m^(6)A) modifications are the most common form of epigenetic regulation at the RNA level and play an essential role in biological processes. However, whether m^(6)A modifications participate in corticospinal tract regeneration after spinal cord injury remains unknown. We found that expression of methyltransferase 14 protein(METTL14) in the locomotor cortex was high after spinal cord injury and accompanied by elevated m^(6)A levels. Knockdown of Mettl14 in the locomotor cortex was not favorable for corticospinal tract regeneration and neurological recovery after spinal cord injury. Through bioinformatics analysis and methylated RNA immunoprecipitation-quantitative polymerase chain reaction, we found that METTL14 regulated Trib2 expression in an m^(6)A-regulated manner, thereby activating the mitogen-activated protein kinase pathway and promoting corticospinal tract regeneration. Finally, we administered syringin, a stabilizer of METTL14, using molecular docking. Results confirmed that syringin can promote corticospinal tract regeneration and facilitate neurological recovery by stabilizing METTL14. Findings from this study reveal that m^(6)A modification is involved in the regulation of corticospinal tract regeneration after spinal cord injury.

关键词： corticospinal tract remodeling epigenetic regulations locomotor cortex m^(6)A modification methyltransferase 14 protein(METTL14) mitogen-activated protein kinase neural regeneration spinal cord injury syringin TRIB2