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An accidental gallbladder schwannoma misdiagnosis as malignant cancer

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Hepatobiliary & Pancreatic Diseases International 2023年第2期22卷 217-220页

作者： Zhen-Hua shen wen-Bin Yuan Qiang Yan Jing Mao qing Zhang Department of Hepatobiliary Pancreatic Surgery Huzhou Central HospitalHuzhou 313003China Department of Stomatology Huzhou Central HospitalHuzhou 313003China

To the Editor: Schwannomas are mainly benign neurogenic tumors originating from the Schwann cells in peripheral nerves sheaths and occur in patients at any age and in every location [ 1, 2 ]. The most common occurring sites of schwannomas are the head, neck and extremities [3]. In the abdominal cavity, the most frequently involved sites are the retroperitoneum and stomach [4].

关键词： stomach nerves cavity

Modal Parameters Identification of A Real Offshore Platform From the Response Excited by Natural Ice Loading

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China Ocean Engineering 2020年第4期34卷 558-570页

作者： YANG wen-long WANG Shu-qing ESI North America Farmington HillsMI 48334USA Shandong Provincial Key Lab of Ocean Engineering Ocean University of ChinaQingdao 266100China

This paper investigates the possibility of utilizing response from natural ice loading for modal parameter identification of real offshore *** test platform is the JZ20-2 MUQ jacket platform located in the Liaodong Bay,China.A field experiment is carried out in winter season,as the platform is excited by floating *** feasibility is demonstrated by the acceleration response of two different *** the SSI-data method,the modal frequencies and damping ratios of four structural modes can be successfully identified from both *** estimated information from both segments is almost identical,which demonstrates that the modal identification is ***,by taking the Jacket platform as a benchmark,the numerical performance of five popular time-domain EMA methods is systematically compared from different *** comparisons are categorized as:(1)stochastic methods versus deterministic methods;(2)high-order methods versus low-order methods;(3)data-driven versus covariance-driven stochastic subspace identification methods.

关键词： modal identification experimental modal analysis offshore platform ambient excitation natural ice loading comparative study

Simulation and Analysis of Dual-Evaporator Refrigeration System for Electric Vehicles

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Automotive Innovation 2020年第4期3卷 347-355页

作者： Ming shen qing Gao State Key Laboratory of Automotive Simulation and Control Jilin UniversityChangchun 130025China College of Automotive Engineering Jilin UniversityChangchun 130025China Department of Thermal Engineering Jilin UniveristyChangchun 130022China

Thermal management system is a crucial part in electric vehicles to ensure battery safety and driving comfort.A refrigerant-based thermal management system of electric vehicles with two evaporators connected in series(series system)or in parallel(parallel system)is *** performances of the two systems are investigated and *** results reveal that the optimal refrigerant charge is approximately 600 ***,there is no correlation between the optimal refrigerant charge,and in the arrangement of heat sinks or the heat *** the optimal refrigerant charge,the coefficient of perfor-mance of the series system ranges from 3.47 to *** coefficient of performance of the parallel system ranges from 3.40 to 4.59,which is lower than that of the series ***,the series system has higher exergy efficiency and better cooling *** heat source(cabin)with a small thermal mass placed in the rear evaporator of the series system can weaken the lag of its cooling *** additional serial evaporator is an alternative solution to the dual-evaporator thermal management system of electric vehicles.

关键词： Lithium-ion battery Thermal management Dual evaporators Simulation analysis

Paris saponin Ⅶ,a direct activator of AMPK,induces autophagy and exhibits therapeutic potential in non-small-cell lung cancer

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Chinese Journal of Natural Medicines 2021年第3期19卷 195-204页

作者： XIANG Yu-Chen shen Jie SI Yuan LIU Xue-wen ZHANG Liang wen Jun ZHANG Te YU qing-qing LU Jun-Fei XIANG Ke LIU Ying Laboratory of Molecular Target Therapy of Cancer Institute of Basic Medical SciencesHubei University of MedicineShiyan 442000China Hubei Key Laboratory of Wudang Local Chinese Medicine Research and Institute of Medicinal Chemistry Hubei University of MedicineShiyan 442000China Hubei Key Laboratory of Embryonic Stem Cell Research Hubei University of MedicineShiyan 442000China Laboratory of Molecular Target Therapy of Cancer Biomedical Research InstituteHubei University of MedicineShiyan 442000China Department of Science and Education Gucheng People’s HospitalHubei University of Arts and ScienceXiangyang 441700China

Paris saponinⅦ(PSⅦ),a bioactive constituent extracted from Trillium tschonoskii Maxim.,is cytotoxic to several cancer *** study was designed to explore whether PSⅦprevents non-small-cell lung cancer(NSCLC)proliferation and to investigate its molecular ***-activated protein kinase(AMPK)has been implicated in the activation of autophagy in distinct *** cultured human NSCLC cell lines,PSⅦinduces autophagy by activating AMPK and inhibiting m TOR ***,PSⅦ-induced autophagy activation was reversed by the AMPK inhibitor compound *** docking analysis showed that PSⅦdirectly interacted with the allosteric drug and metabolite site of AMPK to stabilize its *** thermophoresis assay and drug affinity responsive target stability assay further confirmed the high affinity between PSⅦand *** summary,PSⅦacts as a direct AMPK activator to induce cell autophagy,which inhibits the growth of NSCLC *** the future,PSⅦtherapy should be applied to treat patients with NSCLC.

关键词： Paris saponinⅦ NSCLC Autophagy AMPK

基于CNN和Transformer交叉教学的半监督医学图像分割

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陕西科技大学学报 2025年第1期43卷 185-192页

作者：杨云胡雯青杨虹吴亚男陕西科技大学电子信息与人工智能学院陕西西安710021 西安富德医疗电子有限公司陕西西安710075 西安计量技术研究院陕西西安710199

由于医学图像分割领域缺乏高质量的标注数据,半监督学习方法在医学图像语义分割任务中受到高度重视.为了充分利用卷积神经网络(Convolutional Neural Network,CNN)和Transformer在半监督学习中的优势,本文提出一种基于CNN与Transformer... 详细信息

由于医学图像分割领域缺乏高质量的标注数据,半监督学习方法在医学图像语义分割任务中受到高度重视.为了充分利用卷积神经网络(Convolutional Neural Network,CNN)和Transformer在半监督学习中的优势,本文提出一种基于CNN与Transformer交叉教学的半监督医学图像分割方法.该方法将经典的深度协同训练从一致性正则化简化为交叉教学,利用循环伪标签方案使两个网络的预测差异转换为无监督损失,以鼓励两个网络具有一致的低熵预测.所提方法在ISIC 2018数据集上进行实验,在采用20%的标注比例时,Dice系数和Jaccard系数分别达到87.25%和79.17%,相比于监督U-Net++的训练结果分别提升了2.89%和3.53%,并且优于目前主流的半监督学习方法,验证了所提方法在半监督医学图像分割上的有效性和泛化性.

关键词：半监督学习图像语义分割交叉教学循环伪标签

Geomorphologic patterns of dune networks in the Tengger Desert,China

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Journal of Arid Land 2016年第5期8卷 660-669页

作者： wen qing DONG Zhibao Cold and Arid Regions Environmental and Engineering Research Institute Chinese Academy of Sciences Department of Geography Shaanxi Normal University

Dune networks are widely distributed in the world＇s deserts,which include primary ridges and secondary ***,they have not been sufficiently studied in a systematic manner and their origins and spatial and morphological characteristics remain *** provide information on the geomorphology of dune networks,we analyze the software geomorphologic patterns of the dune networks in China＇s Tengger Desert using matrix and laboratory to process remote-sensing *** on analysis of image features and their layout in a topographic map,we identify two types of dune networks （square and rectangular dune networks） with different size and morphological structures in the Tengger *** important geomorphic pattern parameters,ridge length,spacing,orientation and defect density,are *** length of primary ridges of dune networks decreases from northwest of the desert to the southeast,resulting an increasing spacing and a transition from rectangular dune networks to square dune *** regime and sediment supply are responsible for the variation in pattern *** use the spacing and defect density data to estimate the construction time of dune networks and found that the dune networks in the Tengger Desert formed since about 1.3 ka BP.

关键词： aeolian geomorphology dune networks geomorphological parameters geomorphic pattern analysis Tengger Desert

不同内固定系统治疗股骨转子间骨折的力学稳定性

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中国组织工程研究 2025年第9期29卷 1783-1788页

作者：陈曦汤涛陈铜兵李青张文常州市第一人民医院江苏省常州市213003 苏州大学附属第三医院江苏省常州市213003 苏州大学苏州医学院骨科研究所江苏省苏州市215006

背景:股骨转子间骨折的骨折类型和固定方式多样,各固定系统间的力学稳定性相差较大。使用有限元分析方法对各固定系统开展生物力学研究具有科学的临床意义。目的:通过有限元方法对比分析多种内固定应用于股骨A031-A2.1型转子间骨折的力... 详细信息

背景:股骨转子间骨折的骨折类型和固定方式多样,各固定系统间的力学稳定性相差较大。使用有限元分析方法对各固定系统开展生物力学研究具有科学的临床意义。目的:通过有限元方法对比分析多种内固定应用于股骨A031-A2.1型转子间骨折的力学稳定性。方法:在已验证有效性的股骨有限元模型基础上,对模型进行必要的切割,造模成股骨A031-A2.1型转子间骨折,模拟临床手术方法置入不同的内固定系统,分别建立股骨近端防旋髓内钉、动力髋螺钉、经皮加压钢板和股骨近端锁定钢板固定模型。约束4组模型股骨远端下所有节点,在股骨头上施加700,1400和2100N的压缩载荷,通过计算分析,观察各组模型的等效应力分布和压缩刚度,比较各组模型之间的力学稳定性。结果与结论:①通过计算分析,对比各组模型的变形量计算压缩刚度后,在各级载荷作用下,各组模型上压缩刚度呈现的趋势:生理组>股骨近端防旋髓内钉组>股骨近端锁定钢板组>经皮加压钢板组>动力髋螺钉组;完整的生理组模型的压缩刚度明显高于所有的手术组模型;②观察应力指标,因存在应力遮挡效应,致使各固定组的应力峰值均高于生理组,最大峰值均集中分布于各内固定上;其中股骨近端防旋髓内钉固定组应力峰值最小,动力髋螺钉固定组应力最高,应力分布趋势呈现:生理组<股骨近端防旋髓内钉固定组<经皮加压钢板固定组<股骨近端锁定钢板固定组<动力髋螺钉固定组;③分布于骨质模型的应力,因内固定置入位置不同呈现不同的分布结果;④提示对于股骨转子间骨折,各种内固定均能起到有效的固定,结合有限元分析结果得出股骨近端防旋髓内钉组是较好的一种内固定选择,呈现变形量小、应力峰值低,应力分布均匀的特性;经皮加压钢板组和股骨近端锁定钢板组的力学效果优良,固定效果接近股骨近端防旋髓内钉固定;动力髋螺钉固定效果欠佳,同比于其他内固定,其力学稳定性较差。

关键词：股骨转子间骨折内固定系统力学稳定性有限元分析等效应力压缩刚度

Wave Dissipation Characteristics of A Mountain-Type Breakwater

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China Ocean Engineering 2020年第6期34卷 863-870页

作者： GONG Ye-jun ZHAN Jie-min HU wen-qing FAN qing CAI wen-hao MOE-LCSM School of Mathematics and StatisticsHunan Normal UniversityChangsha 410081China Department of Applied Mechanics and Engineering Sun Yat-sen UniversityGuangzhou 510275China

One mountain-type breakwater consisting of two inclined plates and one vertical plate is proposed based on several types of traditional free surface breakwaters, including the horizontal plate, curtain wall, and trapezoidal barriers. The interaction between the regular waves and the fixed free surface mountain-type breakwater is measured in one wave flume(15.0 m×0.6 m×0.7 m). The wave propagation, reflection, and transmission process are simulated using the VOF method and the hybrid SAS/laminar method. The simulated wave profiles are consistent with the experimental observations. For waves with a length smaller than four times width of the mountain-type breakwater, the reflected wave amplitudes are slightly larger than those of the vertical-plate breakwater, while the wave transmission coefficients are all smaller than 0.5, and the wave loss coefficients are larger than 0.7. The wave energy is dissipated by wave breaking on the windward inclined plate, and turbulent flow around the vertical plate and the leeward inclined plate.

关键词： wave-structure interaction mountain-type breakwater free surface breakwater

High-throughput data-driven interface design of high-energy-density polymer nanocomposites

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Journal of Materiomics 2020年第3期6卷 573-581页

作者： Zhong-Hui shen Yang shen Xiao-Xing Cheng Han-Xing Liu Long-qing Chen Ce-wen Nan State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Center of Smart Materials and DevicesWuhan University of TechnologyWuhan430070China School of Materials Science and Engineering State Key Lab of New Ceramics and Fine ProcessingTsinghua UniversityBeijing100084China Department of Materials Science and Engineering The Pennsylvania State UniversityUniversity ParkPA16802United States

Understanding the interface effect in dielectric nanocomposites is crucial to the enhancement of their *** this work,a data-driven interface design strategy based on high-throughput phase-field simulations is developed to study the interface effect and then optimize the permittivity and breakdown strength of ***,we use two microscopic features that are closely related to the macroscopic dielectric properties,the thickness and permittivity of the interface phases,to evaluate the role of interfaces in experimental configuration,and thus provide quantitative design schemes for the interfacial *** the polyvinyl difluoride(PVDF)-BaTiO_(3) nanocomposite as an example,the calculation results demonstrate that the interfacial polarization could account for up to 83.6% of the increase in the experimentally measured effective permittivity of the *** on the interface optimized strategy,a maximum enhancement of ~156% in the energy density could be achieved by introducing an interface phase with d/r=0.55 and ε_(interface)/ε_(filler)=0:036,compared to the pristine ***,the present work not only provides fundamental understanding of the interface effect in dielectric nanocomposites,but also establishes a powerful data-driven interface design framework for such materials that could also be easily generalized and applied to study interface issues in other functional nanocomposites,such as solid electrolytes and thermoelectrics.

关键词： Interface Polymer nanocomposites Energy storage Data-driven Phase-field simulation