检索结果-南通市图书馆

L-Type Calcium Channel Modulates Low-Intensity Pulsed Ultrasound-Induced Excitation in Cultured Hippocampal Neurons

Neuroscience Bulletin 2024年第7期40卷 921-936页

作者： wen-yong fan Yi-Ming Chen Yi-fan Wang Yu-Qi Wang Jia-Qi Hu wen-Xu Tang Yi Feng Qian Cheng Lei Xue State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433China Department of Physiology and Neurobiology School of Life SciencesFudan UniversityShanghai 200438China Institute of Acoustics School of Physics Science and EngineeringTongji UniversityShanghai 200092China Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration of Ministry of Education Tongji UniversityShanghai 200070China Center for Rehabilitation Medicine Department of Pain ManagementZhejiang Provincial People's HospitalAffliated People's HospitalHangzhou Medical CollegeHangzhou 310014China Department of Critical Care Medicine Shanghai General HospitalShanghai Jiaotong University School of MedicineShanghai 200080China Shanghai Research Institute for Intelligent Autonomous Systems Tongji UniversityShanghai 201210China Research Institute of Intelligent Complex Systems Fudan UniversityShanghai 200433China

As a noninvasive technique,ultrasound stimulation is known to modulate neuronal activity both in vitro and in *** latest explanation of this phenomenon is that the acoustic wave can activate the ion channels and further impact the electrophysiological properties of targeted ***,the underlying mechanism of low-intensity pulsed ultrasound(LIPUS)-induced neuro-modulation effects is still ***,we characterize the excitatory effects of LIPUS on spontaneous activity and the intracellular Ca^(2+)homeostasis in cultured hippocampal *** whole-cell patch clamp recording,we found that 15 min of 1-MHz LIPUS boosts the frequency of both spontaneous action potentials and spontaneous excitatory synaptic currents(sEPSCs)and also increases the amplitude of sEPSCs in hippocampal *** phenomenon lasts for>10 min after LIPUS *** with Ca^(2+)imaging,we clarified that LIPUS increases the[Ca^(2+)]cyto level by facilitating L-type Ca^(2+)channels(LTCCs).In addition,due to the[Ca^(2+)]cyto elevation by LIPUS exposure,the Ca^(2+)-dependent CaMKII-CREB pathway can be activated within 30 min to further regulate the gene transcription and protein *** work suggests that LIPUS regulates neuronal activity in a Ca^(2+)-dependent manner via *** may also explain the multi-activation effects of LIPUS beyond *** stimulation potentiates spontaneous neuronal activity by increasing Ca^(2+)influx.

关键词： Low-intensity pulsed ultrasound Neuromodulation L-type calcium channel Hippocampal neuron

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Effects of aggregate size distribution and carbon nanotubes on the mechanical properties of cemented gangue backfill samples under true triaxial compression

引用

International Journal of Minerals,Metallurgy and Materials 2025年第2期32卷 311-324页

作者： Qian Yin fan wen Zhigang Tao Hai Pu Tianci Deng Yaoyao Meng Qingbin Meng Hongwen Jing Bo Meng Jiangyu Wu State Key Laboratory of Intelligent Construction and Healthy Operation and Maintenance of Deep Underground Engineering China University of Mining and TechnologyXuzhou 221116China State Key Laboratory of Mining Response and Disaster Prevention and Control in Deep Coal Mines Anhui University of Science and TechnologyHuainan 232001China State Key Laboratory for Geomechanics&Deep Underground Engineering China University of Mining and Technology(Beijing)Beijing 100083China Key Laboratory of Xinjiang Coal Resources Green Mining Ministry of EducationXinjiang Institute of EngineeringUrumqi 830023China

The mechanical behavior of cemented gangue backfill materials(CGBMs)is closely related to particle size distribution(PSD)of aggregates and properties of cementitious ***,the true triaxial compression tests,CT scanning,SEM,and EDS tests were conducted on cemented gangue backfill samples(CGBSs)with various carbon nanotube concentrations(P_(CNT))that satisfied fractal theory for the PSD of *** mechanical properties,energy dissipations,and failure mechanisms of the CGBSs under true triaxial compression were systematically *** results indicate that appropriate carbon nanotubes(CNTs)effectively enhance the mechanical properties and energy dissipations of CGBSs through micropore filling and microcrack bridging,and the optimal effect appears at P_(CNT)of 0.08wt%.Taking PSD fractal dimension(D)of 2.500 as an example,compared to that of CGBS without CNT,the peak strength(σ_(p)),axial peak strain(ε_(1,p)),elastic strain energy(Ue),and dissipated energy(U_(d))increased by 12.76%,29.60%,19.05%,and90.39%,***,excessive CNTs can reduce the mechanical properties of CGBSs due to CNT agglomeration,manifesting a decrease inρ_(p),ε_(1,p),and the volumetric strain increment(Δε_(v))when P_(CNT)increases from 0.08wt%to 0.12wt%.Moreover,the addition of CNTs improved the integrity of CGBS after macroscopic failure,and crack extension in CGBSs appeared in two modes:detour and pass through the ***σ_(p)and U_(d)firstly increase and then decrease with increasing D,and porosity shows the opposite ***ε_(1,p)andΔε_(v)are negatively correlated with D,and CGBS with D=2.150 has the maximum deformation parameters(ε_(1,p)=0.05079,Δε_(v)=0.01990)due to the frictional slip effect caused by coarse *** increasing D,the failure modes of CGBSs are sequentially manifested as oblique shear failure,"Y-shaped"shear failure,and conjugate shear failure.

关键词： cemented gangue backfill materials particle size distribution true triaxial compression test carbon nanotubes mechanical properties failure modes

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Light tuning CO/H_(2)composition on Ag:Unraveling CO_(2)mass transfer and electron-phonon coupling in plasmon-enhanced electrocatalysis

引用

Nano Research 2025年第1期18卷 173-185页

作者： Rui Lin Dong fan Luca MBerger Thomas Possmayer Yu Zhou Jiexin Zhu Xingbao Chen wen Luo Lars Allmendinger Andreas Tittl Leonardo de Souza Menezes Guillaume Maurin Shihe Yang and Stefan AMaier Nanoinstitute Munich Faculty of PhysicsLudwig-Maximilians-Universität München80539 MunichGermany Institut Charles Gerhardt Montpellier UMR 5253 CNRS ENSCM UniversitéMontpellierPlace E.Bataillon34090 MontpellierFrance Guangdong Provincial Key Lab of Nano-Micro Material Research School of Advanced MaterialsPeking University Shenzhen Graduate SchoolShenzhen 518055China State Key Laboratory of Advanced Technology for Materials Synthesis and Processing Wuhan University of TechnologyWuhan 430070China Faculty of Chemistry and Pharmacy Ludwig-Maximilians-Universität München81377 MunichGermany Departamento de Física Universidade Federal de Pernambuco50670-901 Recife-PEBrazil School of Physics and Astronomy Monash University Clayton CampusMelbourneVictoria 3800Australia Department of Physics Imperial College LondonSW72AZ LondonUK

Plasmon-enhanced electrocatalysis(PEEC)is an emerging approach to mitigate CO_(2)*** mechanisms behind CO_(2)adsorption and reduction at the catalyst-electrolyte interface in PEEC still need to be further ***,we employ a well-defined Ag nanostructure to elucidate these pivotal *** shining light with wavelengths of 625,525,405 nm on Ag,an adjustable CO/H_(2)ratio from 35 to 1 can be *** reaction pathway changing under plasmonic excitation does not originate from the lowered CO_(2)mass transfer in the vicinity of Ag,as the electrochemical quartz crystal microbalance results unravel that a slightly elevated temperature in bulk electrolyte caused by light irradiation cannot weaken the CO_(2)adsorption at the Ag catalyst-electrolyte *** calculations reveal that optical excitation towards shorter wavelengths leads to a progressive lowered energy barrier for H_(2)formation together with an enhanced energy barrier for^(*)COOH *** thermodynamically suppressed,CO_(2)reduction can still be improved kinetically by optimizing the excitation wavelength and intensity,being accompanied with the enhanced *** absorption spectroscopy results further correlate the higher photocurrent with a prolonged electron-phonon coupling time,verifying that the improvement of CO_(2)reduction kinetics in PEEC can be realized by hot electron harnessing.

关键词： plasmonic catalysis photoelectrochemical CO_(2)reduction CO/H_(2)ratio hot electron generation electronphonon coupling thermal effect

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

锤击法在手扶拖拉机动态特性研究中的应用

引用

农业机械学报 1984年第3期 21-29页

作者：苏清祖王锦雯范永法江苏工学院

本文简述了用锤击法进行模态分析的基本原理以及用锤击法测取手扶拖拉机传递函数的试验技术,并从测取的传递函数数据中直接进行某些模态参数的识别,结果表明锤击法是对拖拉机某些零部件动态特性测定的一种简易可行的方法。

关键词：传递函数虚部转移函数动态特性手扶拖拉机田园式拖拉机锤击法

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Performance Evaluation of Advanced Wave Energy Converters in the Nearshore Areas of the North Indian Ocean

引用

China Ocean Engineering 2022年第6期36卷 980-993页

作者： WAN yong ZHANG wen fan Chen-qing LI Li-gang DAI yong-shou The College of Oceanography and Space Informatics China University of PetroleumQingdao 266580China The Laboratory of Physical Oceanography and Remote Sensing The First Institute of OceanographySOAQingdao 266061China

The 21st Century Maritime Silk Road is a profound measure for mankind,whilst its development is severely restricted by the energy shortage of surrounding *** the core construction area of Maritime Silk Road,the North Indian Ocean is rich in wave *** development and utilization of wave energy not only can overcome energy shortage,but also promote communication between peripheral ***,previous researchers often focused on wave energy itself,without combining devices to analyze wave energy ***,we conducted an overall assessment of wave energy resources using 20-year ERA5 data and determined the sites considered as superior for the construction of Wave Energy Farm(WEF)in the coastal *** order to point out which type of Wave Energy Converter(WEC)is best suited for the sites,we carried out the performance evaluation of eight advanced WECs using three parameters:the mean power output,the capacity factor and the capture width *** results show that the performance of Wave Star is superior to other devices,which is supposed to be the primary consideration of the Wave Energy Farms(WEFs)in the future.

关键词： ocean energy wave energy characteristics site selection wave energy converter performance evaluation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

锗锡浓度对硅锗锡合金性能影响的研究

引用

原子与分子物理学报 2025年第5期42卷 163-174页

作者：顾永顺温淑敏内蒙古工业大学理学院呼和浩特010051

由于SiGeSn合金材料其具有高的载流子迁移率和较长的载流子寿命,并且其结构具有较高的热力学稳定性,所以在光电子领域中是一种具有非常大应用潜力的半导体材料.本文采用密度泛函理论中的广义梯度近似GGA+U的方法,构建并计算了本征半导体... 详细信息

由于SiGeSn合金材料其具有高的载流子迁移率和较长的载流子寿命,并且其结构具有较高的热力学稳定性,所以在光电子领域中是一种具有非常大应用潜力的半导体材料.本文采用密度泛函理论中的广义梯度近似GGA+U的方法,构建并计算了本征半导体Si_(96)与五组掺杂模型Si_(92)Ge_(2)Sn_(2)、Si_(88)Ge_(4)Sn_(4)、Si_(84)Ge_(6)Sn_(6)、Si_(80)Ge_(8)Sn_(8)、Si_(76)Ge_(10)Sn_(10)的电子结构及光学性质.通过对计算结果的分析可知,Ge,Sn的加入使得Si材料的带隙宽度减小,并且发生了由间接带隙向直接带隙的转变;Ge,Sn浓度最高的SiGeSn合金的形成能相对较高,稳定性相较于Ge,Sn含量低的材料较差;随着Ge,Sn掺杂浓度的提高,电子态密度图显示出越来越明显的杂化现象,并且态密度的峰值主要有Si原子的s轨道提供;Ge,Sn浓度的提高还使得SiGeSn合金的吸收系数在可见光及近红外区域内增加、反射率在可见光及以上波段范围内提高、折射率变低、消光系数曲线向红外区域移动等光学性质变化,表明可以通过调节Ge,Sn浓度来获得合适的光学特性,这为SiGeSn半导体在红外区域光电材料和器件的应用上提供了研究方向.

关键词： SiGeSn 电子特性光学性质

来源：

维普期刊数据库博看期刊

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Molecular insight into the GaP(110)-water interface using machine learning accelerated molecular dynamics

引用

Journal of Energy Chemistry 2023年第7期82卷 239-247,I0006页

作者： Xue-Ting fan Xiao-Jian wen yong-Bin Zhuang Jun Cheng State Key Laboratory of Physical Chemistry of Solid Surfaces iChEMCollege of Chemistry and Chemical EngineeringXiamen UniversityXiamen 361005FujianChina Shenzhen Research Institute of Xiamen University Shenzhen 518057GuangdongChina Innovation Laboratory for Sciences and Technologies of Energy Materials of Fujian Province(IKKEM) Xiamen 361005FujianChina

GaP has been shown to be a promising photoelectrocatalyst for selective CO_(2)reduction to *** to the relevance of the interface structure to important processes such as electron/proton transfer,a detailed understanding of the GaP(110)-water interfacial structure is of great *** initio molecular dynamics(AIMD)can be used for obtaining the microscopic information of the interfacial ***,the GaP(110)-water interface cannot converge to an equilibrated structure at the time scale of the AIMD *** this work,we perform the machine learning accelerated molecular dynamics(MLMD)to overcome the difficulty of insufficient sampling by *** the help of MLMD,we unravel the microscopic information of the structure of the GaP(110)-water interface,and obtain a deeper understanding of the mechanisms of proton transfer at the GaP(110)-water interface,which will pave the way for gaining valuable insights into photoelectrocatalytic mechanisms and improving the performance of photoelectrochemical cells.

关键词： Photoelectrocatalysis GaP(110)-water interface Machine learning accelerated molecular dynamics

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effect of Deformation Temperatures on Microstructure of AQ80 Magnesium Alloy under Repeated Upsetting-Extrusion

引用

Acta Metallurgica Sinica(English Letters) 2023年第10期36卷 1649-1664页

作者： Yutian fan Liwei Lu Hongliang Zhao Zhiqiang Wu yong Xue wen Wang School of Materials Science and Engineering Hunan University of Science and TechnologyXiangtan411201China College of Materials Science and Engineering Zhengzhou UniversityZhengzhou450001China School of Material Science and Engineering North University of ChinaTaiyuan030051China School of Metallurgical Engineering National and Local Joint Engineering Research Center for Functional Materials ProcessingXi’an University of Architecture and TechnologyXi’an710055China

A new repeated upsetting-extrusion (RUE) process was proposed to improve the microstructure and the mechanical properties of Mg alloys. The effects of deformation temperature on the microstructure and microhardness of RUEed AQ80 Mg alloy were studied. The results showed that Mg alloy is subjected to sufficient corner shear deformation, upsetting deformation, and extrusion deformation, resulting in a large and uniformly distributed effective strain after RUE deformation. The microstructure is refined to an average grain size of 2.1 μm by the continuous dynamic recrystallization (CDRX) mechanism at 250 °C. As the temperature increases to 300 °C, the discontinuous dynamic recrystallization (DDRX) mechanism is activated and the average grain size is refined to 1.6 µm by the combined effect of CDRX and DDRX. In comparison to their parent grains, the orientations of the CDRXed grains show a clearly preferred orientation, but those of the DDRXed grains are completely different. At 350 °C, {10-12} extension twins appear in the microstructure, and the twinning-induced recrystallization (TDRX) mechanism plays an important role in grain refinement. With the two strengthening mechanisms of fine-grained strengthening and dislocation strengthening, the microhardness of the 250 °C sample is greatly improved, with an increase of about 35.1% compared to the initial sample.

关键词： AQ80 Mg alloy Repeated upsetting-extrusion Microstructure Microhardness

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Combined Subchronic Toxicity of Bisphenol A and Dibutyl Phthalate on Male Rats

引用

Biomedical and Environmental Sciences 2013年第1期26卷 63-69页

作者： ZHANG wen Zhong yong Ling JIA Xu Dong LI Ning fan yong Xiang China National Center for Food Safety Risk Assessment

Objective To evaluate the combined subchronic toxicity of bisphenol A（BPA） and dibutyl phthalate（DBP） in male Sprague Dawley（SD） *** Forty 4‐week‐old male rats weighing 115‐125 g were randomly divided into BPA‐treated,DBP‐treated group,BPA＋DBP‐treated and control groups and fed with a soy‐ and alfalfa‐free diet containing 285.4 ppm BPA,285.4 ppm DBP,285.4 ppm BPA plus 285.4 ppm DBP,and a control diet,respectively,for 90 consecutive *** the end of the study,the animals were sacrificed by exsanguination via the carotid artery under diethyl etherane aesthesia and ***,including liver,kidneys,spleen,thymus,heart,brain,and testis underwent pathological *** androgen receptor（AR）,gonadotropin‐releasing hormone receptor（GNRHR）,and progesterone hormone receptor（PR） genes from the hypothalamus were detected by real‐time *** biomedical parameters were *** No significant difference was found in food intake,body weight,tissue weight,organ/brain weight ratio,and biomedical parameters among the four groups（P〉0.05）.However,BPA and DBP up‐regulated AR,PR and GNRHR expression levels in rats and showed a synergistic or an additive effect in the BPA＋DBP *** The combined subchronic toxicity of BPA and DBP is synergistic or additive in male SD rats.

关键词： Bisphenol A Dibutyl phthalate Combined subchronic toxicity Sprague dawley rat Endocrine disruption

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Geochemical identification of a source rock affected by migrated hydrocarbons and its geological significance:Fengcheng Formation,southern Mahu Sag,Junggar Basin,NW China

引用

Petroleum Science 2024年第1期21卷 100-114页

作者： wen-Long Dang Gang Gao Xin-Cai You Ke-Ting fan Jun Wu De-wen Lei wen-Jun He yong Tang State Key Laboratory of Petroleum Resource and Prospecting China University of Petroleum(Beijing)Beijing102249China School of GeoSciences China University of Petroleum(Beijing)Beijing102249China Exploration&Development Institute Xinjiang Oil Field CompanyKaramay834000XinjiangChina

The Fengcheng Formation is a crucial source rock and the primary reservoir for oil accumulation in the Mahu *** oils are distributed throughout the Fengcheng Formation,ranging from the edge to the interior of the sag in the southern Mahu *** crude oils originate from in-situ source rocks in shallowly buried areas and the inner deep *** migration,the crude oil from the inner deep sag affects the source rocks close to carrier beds,leading to changes in the organic geochemical characteristics of the source *** changes might alter source rock evaluations and oil-source *** on data such as total organic carbon(TOC),Rock-Eval pyrolysis of source rocks,and gas chromatography-mass spectrometry(GC-MS)of the saturated fraction,and considering the geological characteristics of the study area,we define the identification characteristics of source rock affected by migrated hydrocarbons and establish the various patterns of influence that migrated hydrocarbons have on the source rock of the Fengcheng Formation in the southern Mahu *** source rocks of the Fengcheng Formation are mostly fair to good,containing mainly Type II organic matter and being thermally mature enough to generate *** rocks affected by migrated hydrocarbons exhibit relatively high hydrocarbon contents(S1/TOC>110 mg HC/g TOC,Extract/TOC>30%,HC:hydrocarbon),relatively low Rock-Eval Tmax values,and relatively high tricyclic terpane contents with a descending and mountain-shaped ***,biomarker composition parameters indicate a higher thermal maturity than in-situ source *** a comparison of the extract biomarker fingerprints of adjacent reservoirs and mudstones in different boreholes,three types of influence patterns of migrated hydrocarbons are identified:the edge-influence of thin sandstone-thick mudstone,the mixed-influence of sandstone-mudstone interbedded,and the full-influence of thick sandstone-thin *** finding reminds

关键词： Organic geochemistry Source rock Influence of migrated hydrocarbons Fengcheng Formation Southern Mahu Sag

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：