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Highly adaptive triboelectric tactile sensor on the foot of autonomous wall-climbing robots for detecting the adhesion state and avoiding the hazard

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Nano Research 2024年第7期17卷 6518-6526页

作者： Zhaoyang wang Jianhua Liu Ziyu wang Chang Liu Qingyu Chen Chaofan Zhang Wenbo Zhang Jicang Si xiu Xiao Peng Xu Minyi Xu Dalian Key Lab of Marine Micro/Nano Energy and Self-powered System Marine Engineering CollegeDalian Maritime UniversityDalian 116026China Information Science and Technology College Dalian Maritime UniversityDalian 116026China Navigation College Dalian Maritime UniversityDalian 116026China Intelligent Biomimetic Design Lab College of EngineeringPeking UniversityBeijing 100871China

Due to the excellent maneuverability and obstacle crossing of legged robots,it is possible for an autonomous legged wallclimbing robots to replace manual inspection of ship exterior ***,when the magnetic adsorption legged wallclimbing robot steps on the convex point or convex line of the wall,or even when the robot missteps,the robot is likely to detach from the ferromagnetic ***,this paper proposes a tactile sensor for the legged magnetic adsorption wall-climbing robot to detect the magnetic adsorption state and improve the safety of the autonomous crawling of the *** tactile sensor mainly comprises a three-dimensional(3D)-printed shell,a tactile slider,and three isometric sensing units,with an optimized *** experiment shows that the triboelectric tactile sensor can monitor the sliding depth of the tactile slider and control the light-emitting device(LED)signal *** addition,in the demonstration experiment of detecting the adsorption state of the robot's foot,the triboelectric tactile sensor has strong adaptability to various ferromagnetic wall ***,this study establishes a robot gait control system to verify the feedback control ability of the triboelectric tactile *** results show that the robot equipped with the triboelectric tactile sensor can recognize the dangerous area on the crawling wall and autonomously avoid the ***,the proposed triboelectric tactile sensor has great potential in realizing the tactile sensing ability of robots and enhancing the safety and intelligent inspection of ultra-large vessels.

关键词： legged wall-climbing robot ship inspection tactile perception triboelectric sensor

Design and Cryogenic Performance of a Hexapod Platform for a Large Ground-based Wide Field Survey Telescope

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Research in Astronomy and Astrophysics 2024年第1期24卷 178-187页

作者： Yang yu Xue-Wen wang yu Zhang Jia-Lin Sun Zhen-Bang Xu Jian-Li wang Changchun Institute of Optics Fine Mechanics and PhysicsChinese Academy of SciencesChangchun 130033China Chinese Academy of Sciences Key Laboratory of On-orbit Manufacturing and Integration for Space Optics System Changchun 130033China University of Chinese Academy of Sciences Beijing 100049China

The thermal gradient is an important factor that causes degradation to the image quality of telescopes. In order to ensure the accurate alignment of the primary focus unit and the primary mirror, the hexapod platform(as a corrector) is investigated in this paper. First, a ground-based telescope with 2.5 m aperture and 3.5 deg field of view is described. The telescope is under construction, and it is expected to be finished in 2023. Second, the hexapod platform with flexure hinges utilized to adjust the primary focus unit is proposed, which is applied as a ***, the inverse kinematics of the platform is established and an open-loop control system is built based on ***, the cryogenic performance test for the hexapod platform is performed. The experimental results show that the resolution and repeatability of the translation for the hexapod platform can be achieved at the micrometer *** resolution and repeatability of the rotation can be achieved at the arc-second level. Therefore, the cryogenic performance of the hexapod platform can meet the optical imaging requirements of the wide-field ground-based telescope. The kinematic analysis and cryogenic performance tests in the paper provide a technical reference for the precise alignment of the primary focus unit and the primary mirror, which can improve the imaging quality of the telescope.

关键词： methods:miscellaneous space vehicles:instruments telescopes miscellaneous

Uncovering Chemical Interactions between Danshen and Danggui Using Liquid Chromatography–Mass Spectrometry and Network Pharmacology-Based Research on Stroke

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World Journal of Traditional Chinese Medicine 2024年第2期10卷 230-243页

作者： Han-Qing Pang Jia-xiu Guo Xiao-yu Shang Jian wang Hui Liu Jing Tian Lu Zhang Jian-Bin wang Wei Shi Bing-Chun Yan Liang Liu Department of Pharmacy School of MedicineInstitute of Translational MedicineYangzhou UniversityYangzhouChina School of Medicine Jiangsu Key Laboratory of Integrated Traditional Chinese and Western Medicine for Prevention and Treatment of Senile DiseasesYangzhou UniversityYangzhouChina School of Chemistry and Pharmaceutical Sciences State Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources(Guangxi Normal University)GuilingChina Yangzhou Food and Drug Inspection and Testing Center YangzhouChina

Objective: The objective of this study was to decipher chemical interactions between Danshen and Danggui using liquid chromatography–mass spectrometry(LC-MS) and explore the mechanisms of Danshen–Danggui against stroke using network pharmacology and molecular docking. Materials and Methods: First, the chemical compounds of Danshen–Danggui were profiled using ultra-high-performance liquid chromatography(HPLC)-quadrupole time-of-flight MS. Accurately characterized compounds in various proportions of Danshen–Danggui were quantified using HPLC combined with triple quadrupole electrospray tandem MS. Network pharmacology was used to uncover the essential mechanisms of action of Danshen–Danggui against stroke. Discovery Studio Software was used for the molecular docking verification of key active chemicals and stroke-related targets. Results: A total of 53 compounds were characterized, and 22 accurately identified constituents(10 phenolic acids, 8 phthalides, and 4 tanshinones) were quantified in 15 proportions of Danshen–Danggui. The quantification results showed that Danggui significantly increased the dissolution of most phenolic acids(compounds from Danshen), whereas Danshen promoted the dissolution of most phthalides(compounds from Danggui). Overall, the combination of Danshen and Danggui at a 1:1 ratio resulted in the maximum total dissolution rate. Further network pharmacology and molecular docking results indicated that Danshen–Danggui exerted anti-stroke effects mainly by regulating inflammation-related(tumor necrosis factor, hypoxia-inducible factor, and toll-like receptor) signaling pathways, which ranked among the top three pathways based on Kyoto Encyclopedia of Genes and Genomes(KEGG) enrichment analysis. Conclusion: The chemical compounds in Danshen–Danggui could interact with each other to increase the dissolution of the most active compounds, which could provide a solid basis for uncovering the compatibility mechanisms of Danshen–Danggui and Danshen–Danggu

关键词： Chemical interactions Danggui Danshen liquid chromatography–mass spectrometry network pharmacology

Organic interfacial engineering of gold nanowires for selective glycerol electrooxidation

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Chinese Chemical Letters 2024年第3期35卷 502-507页

作者： Zhe wang Qingling Hong Boqiang Miao Tianjiao wang yu Ding Pujun Jin Pei Chen yu Chen Key Laboratory of Macromolecular Science of Shaanxi Province Key Laboratory of Applied Surface and Colloid Chemistry(Ministry of Education)Shaanxi Key Laboratory for Advanced Energy DevicesSchool of Materials Science and EngineeringShaanxi Normal UniversityXi'an 710062China

The selective electrochemical conversion of glycerol into value-added products is a green and sustainable strategy for the biomass *** this work,Au nanowires(Au-NW)modified with polyethyleneimine(PEI)molecule(Au-NW@PEI)is obtained by an up-bottom post-modification *** characterization,molecular dynamics simulation and density functional theory demonstrate that the loose-packed PEI monolayer firmly and uniformly distribute on the Au-NW surface due to the strong Au-N *** experiments and product analysis display that PEI modification significantly enhance the electro-activity of Au-NW for the glycerol electro-oxidation reaction(GEOR)due to the electronic ***,the steric hindrance and electrostatic effect of PEI layer make the optimizing adsorption of intermediates ***,the selectivity of C3 product glyceric acid over Au-NW@PEI is increased by nearly 20%.The work thus indicates that the rational design of metal-organic interface can effectively elevate the electro-activity and selectivity of Au nanostructures,which may have wide application in biomass development.

关键词： Glycerol electrooxidation reaction Organic interface engineering Gold-based nanomaterials Electrocatalysis Selectivity

Optimized parameters of downhole all-metal PDM based on genetic algorithm

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Petroleum Science 2024年第4期21卷 2663-2676页

作者： Jia-Xing Lu Ling-Rong Kong yu wang Chao Feng yu-Lin Gao China University of Geosciences (Beijing) Key Laboratory on Deep Geo-Drilling Technology of Ministry of Natural Resources

Currently, deep drilling operates under extreme conditions of high temperature and high pressure,demanding more from subterranean power motors. The all-metal positive displacement motor, known for its robust performance, is a critical choice for such drilling. The dimensions of the PDM are crucial for its performance output. To enhance this, optimization of the motor's profile using a genetic algorithm has been undertaken. The design process begins with the computation of the initial stator and rotor curves based on the equations for a screw cycloid. These curves are then refined using the least squares method for a precise fit. Following this, the PDM's mathematical model is optimized, and motor friction is assessed. The genetic algorithm process involves encoding variations and managing crossovers to optimize objective functions, including the isometric radius coefficient, eccentricity distance parameter,overflow area, and maximum slip speed. This optimization yields the ideal profile parameters that enhance the motor's output. Comparative analyses of the initial and optimized output characteristics were conducted, focusing on the effects of the isometric radius coefficient and overflow area on the motor's performance. Results indicate that the optimized motor's overflow area increased by 6.9%, while its rotational speed reduced by 6.58%. The torque, as tested by Infocus, saw substantial improvements of38.8%. This optimization provides a theoretical foundation for improving the output characteristics of allmetal PDMs and supports the ongoing development and research of PDM technology.

关键词： Positive displacement motor Genetic algorithm Profile optimization Matlab programming Overflow area

Association of Human Whole-blood NAD+Levels with Nabothian Cyst

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Biomedical and Environmental Sciences 2024年第5期37卷 471-478页

作者： XU Ling wang yue Xuan wang Wei FAN Xue CHEN Xue yu ZHOU Tian yun LIU yu He yu Ye YANG Fan JU Zhen yu ZHOU Yong wang Deng Liang Clinical Research Institute Shanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China NHC Key Lab of Reproduction Regulation Shanghai Engineering Research Center of Reproductive Health Drugs and DevicesShanghai Institute for Biomedical and Pharmaceutical TechnologiesShanghai 200237China Department of Applied Statistics Johannes Kepler University LinzLinz 4040Austria Hematology Center Beijing Key Laboratory of Pediatric Hematology OncologyNational Key Discipline of Pediatrics(Capital Medical University)Key Laboratory of Major Diseases in ChildrenMinistry of EducationBeijing Children's HospitalCapital Medical UniversityNational Center for Children's HealthBeijing 100045China Department of Biostatistics School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012ShandongChina Clinical Medicine School of Basic MedicineShanghai Medical College Fudan UniversityShanghai 200032China Department of Biochemistry and Molecular Biology Hengyang Medical SchoolUniversity of South ChinaHengyang 421001HunanChina Administrative Office Total Quality Management OfficeTotal Quality Management InstituteShanghai General HospitalShanghai Jiao Tong University School of MedicineShanghai 200080China The First Affiliated Hospital of Jinan University Institute of Aging and Regenerative MedicineJinan UniversityJinan 510632GuangzhouChina Department of Scientific Research The First Affiliated Hospital of Huzhou UniversityHuzhou 313000ZhejiangChina Department of Neurosurgery Neurosurgery Research InstituteThe First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Department of Neurosurgery Binhai Branch of National Regional Medical CenterThe First Affiliated HospitalFujian Medical UniversityFuzhou 350209FujianChina Fujian Provincial Institutes of Brain Disorders and Brain Sciences The First Affiliated HospitalFujian Medical UniversityFuzhou 350005FujianChina Fujian Provincial Clinical Research Center for Neurological

Objective Little is known about the association between whole-blood nicotinamide adenine dinucleotide(NAD^(+))levels and nabothian *** study aimed to assess the association between NAD^(+)levels and nabothian cysts in healthy Chinese *** Multivariate logistic regression analysis was performed to analyze the association between NAD^(+)levels and nabothian *** The mean age was 43.0±11.5 years,and the mean level of NAD^(+)was 31.3±5.3μmol/*** cysts occurred in 184(27.7%)participants,with single and multiple cysts in 100(15.0%)and84(12.6%)participants,*** total nabothian cyst prevalence gradually decreased from37.4%to 21.6%from Q1 to Q4 of NAD^(+)and the prevalence of single and multiple nabothian cysts also decreased across the NAD^(+)*** compared with the highest NAD^(+)quartile(≥34.4μmol/L),the adjusted odds ratios with 95%confidence interval of the NAD^(+)Q1 was 1.89(1.14–3.14)for total nabothian *** risk of total and single nabothian cysts linearly decreased with increasing NAD^(+)levels,while the risk of multiple nabothian cysts decreased more rapidly at NAD^(+)levels of 28.0 to35.0μmol/***:Low NAD^(+)levels were associated with an increased risk of total and multiple nabothian cysts.

关键词： Nicotinamide adenine dinucleotide Nabothian cyst Female Risk factor

Multidimensional regulation of Ti-Zr-Cr-Mn hydrogen storage alloys via Y partial substitution

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Nano Research 2024年第5期17卷 4211-4220页

作者： Haixiang xiu Wanqiang Liu Dongming Yin Nan Ding Wenfeng Qiao Shaolei Zhao Long Liang Cong Liu Shaohua wang Qingshuang wang Bingbing Chen Limin wang Yong Cheng School of Materials Science and Engineering Changchun University of Science and TechnologyChangchun 130022China State Key Laboratory of Rare Earth Resources Utilization Changchun Institute of Applied ChemistryChinese Academy of Sciences(CAS)Changchun 130022China School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei 230026China Department of Energy Science and Engineering Nanjing Tech UniversityNanjing 211816China National Engineering Research Center of Nonferrous Metals Materials and Products for New Energy GRINM Group Co.Ltd.Beijing 100088China GRIMAT Engineering Institute Co. Ltd.Beijing 101407China College of Life Science and Technology Changchun University of Science and TechnologyChangchun 130022China

High density and safe storage of hydrogen are the preconditions for the large-scale application of hydrogen ***,the hydrogen storage properties of Ti_(0.6)Zr_(0.4)Cr_(0.6)Mn_(1.4) alloys are systematically studied by introducing Y element instead of Ti element through vacuum arc *** the partial substitution of Y,a second phase of rare earth oxide is added in addition to the main suction hydrogen phase,C14 Laves *** to the unique properties of rare earth elements,the partial substitution of Y can not only improve the activation properties and plateau pressure of the alloys,but also increase the effective hydrogen storage capacity of the *** comprehensive properties of hydrogen storage alloys are improved by multidimensional regulation of rare earth *** them,Ti_(0.552)Y_(0.048)Zr_(0.4)Cr_(0.6)Mn_(1.4) has the best comprehensive *** alloy can absorb hydrogen without activation at room temperature and 5 MPa,with a maximum hydrogen storage capacity of 1.98 wt.%.At the same time,it reduces the stability of the hydride and the enthalpy change value,making it easier to release *** theoretical analysis and first-principle simulation,the results show that the substitution of Y element reduces the migration energy barrier of hydrogen and the structural stability of the system,which is conducive to hydrogen *** alloy has superior durability compared to the original alloy,and the capacity retention rate was 96.79%after 100 hydrogen absorption/desorption cycles.

关键词： AB_(2)-type hydrogen storage alloy rare earth element first-principles simulation multidimensional regulation

Subtype Identification of Avian Influenza Virus on DNA Microarray

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Agricultural Sciences in China 2005年第9期4卷 700-706页

作者： wang xiu-rong yu Kang-zhen DENG Guo-hua SHI Rui LIU Li-ling QIAO Chuan-ling BAO Hong-mei KONG Xian-gang CHEN Hua-lan Animal Influenza Laboratory of the Ministry of Agriculture and National Key Laboratory of Veterinary Biotechnology of Harbin VeterinaryResearch Institute of Chinese Academy of Agricultural Sciences Harbin 150001 P.R.China

We have developed a rapid microarray-based assay for the reliable detection of H5, H7 and H9 subtypes of avian influenza virus （AIV）. The strains used in the experiment were A/Goose/Guangdong/1/96 （H5N1）, A/African starling/983/79 （H7N1） and A/Turkey/Wiscosin/1/66 （H9N2）. The capture DNAs clones which encoding approximate 500-bp avian influenza virus gene fragments obtained by RT-PCR, were spotted on a slide-bound microarray. Cy5-labeled fluorescent cDNAs, which generated from virus RNA during reverse transcription were hybridized to these capture DNAs. These capture DNAs contained multiple fragments of the hemagglutinin and matrix protein genes of AIV respectively, for subtyping and typing AIV. The arrays were scanned to determine the probe binding sites. The hybridization pattern agreed approximately with the known grid location of each target. The results show that DNA microarray technology provides a useful diagnostic method for AIV.

关键词： Avian influenza virus DNA microarray Subtype identification

Identification of novel mammalian viruses in tree shrews(Tupaia belangeri chinensis)

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Zoological Research 2024年第2期45卷 429-438页

作者： Hong Zhou Ren-Rong Tian xiu-Rong wang Jin-Xuan Yang yun-Xiao wang Ming-Liang Zhao Xu-Dong Zhang yu-Hua Ma Long-Bao Lv Edward CHolmes Yong-Tang Zheng Wei-Feng Shi School of Clinical and Basic Medical Sciences Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China Key Laboratory of Emerging Infectious Diseases in Universities of Shandong Shandong First Medical University and Shandong Academy of Medical SciencesTaianShandong 271000China Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of yunnan Province KIZ-CUHK Joint Laboratory of Bioresources and Molecular Research in Common DiseasesCenter for Biosafety Mega-ScienceKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650223China School of Public Health Shandong First Medical University&Shandong Academy of Medical SciencesJi’nanShandong 250117China National Resource Center for Non-Human Primates Kunming Primate Research CenterKunming Institute of ZoologyChinese Academy of SciencesKunmingYunnan 650107China Sydney Institute for Infectious Diseases School of Medical SciencesThe University of SydneySydneyNew South Wales 2006Australia Department of Infectious Diseases Ruijin HospitalShanghai Jiao Tong University School of MedicineShanghai 200025China Shanghai Institute of Virology Shanghai Jiao Tong University School of MedicineShanghai 200025China

The Chinese tree shrew(Tupaia belangeri chinensis),a member of the mammalian order Scandentia,exhibits considerable similarities with primates,including humans,in aspects of its nervous,immune,and metabolic *** similarities have established the tree shrew as a promising experimental model for biomedical research on cancer,infectious diseases,metabolic disorders,and mental health ***,we used metatranscriptomic sequencing to analyze plasma,as well as oral and anal swab samples,from 105 healthy asymptomatic tree shrews to identify the presence of potential zoonotic *** total,eight mammalian viruses with complete genomes were identified,belonging to six viral families,including Flaviviridae,Hepeviridae,Parvovirinae,Picornaviridae,Sedoreoviridae,and ***,the presence of rotavirus was recorded in tree shrews for the first *** viruses-hepacivirus 1,parvovirus,and picornavirus-exhibited low genetic similarity(94%)to known viral *** analyses also revealed that the rotavirus and mammalian orthoreovirus identified in this study may be novel *** findings provide insights into the diverse viral spectrum present in captive Chinese tree shrews,highlighting the necessity for further research into their potential for crossspecies transmission.

关键词： Tree shrew(Tupaia belangeri chinensis) Meta-transcriptomic sequencing Mammalian viruses Genomic analysis