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基于人工神经网络的柔性机翼挠度预测

北京航空航天大学学报 2011年第4期37卷 405-408,414页

作者：王志飞王华贾青萍韩晶北京航空航天大学宇航学院北京100191

为实现对承载后柔性机翼挠度的准确预测,在全面分析柔性机翼挠度的影响因素基础上,应用正交试验法确定的影响柔性机翼挠度的主要因子作为输入变量,挠度作为输出变量,以大量试验数据为训练样本,通过多次试取隐含层和各隐含单元,并选取tra... 详细信息

为实现对承载后柔性机翼挠度的准确预测,在全面分析柔性机翼挠度的影响因素基础上,应用正交试验法确定的影响柔性机翼挠度的主要因子作为输入变量,挠度作为输出变量,以大量试验数据为训练样本,通过多次试取隐含层和各隐含单元,并选取trainlm作为最优训练函数,最终建立了预测柔性机翼挠度的BP(Back Propagation)人工神经网络模型.在此基础上,随机选取试验结果中的12组试验样本,连续进行10次挠度预测,预测结果和试验实测值最大相对误差和标准方差分别为4.481%,1.033 7.解析结果表明:柔性机翼挠度预测结果与实验值吻合的较好,建立的人工神经网络预测模型具有较高的预测精度.

关键词：柔性机翼 BP神经网络挠度预测

Memory-assisted quantum accelerometer with multi-bandwidth

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Photonics Research 2022年第4期10卷 1022-1030页

作者： zhifei Yu Bo Fang Liqing Chen Keye Zhang Chun-hua Yuan Weiping Zhang State Key Laboratory of Precision Spectroscopy School of Physics and Electronic ScienceEast China Normal UniversityShanghai 200062China Shanghai Research Center for Quantum Sciences Shanghai 201315China School of Physics and Astronomy Shanghai Jiao Tong Universityand Tsung-Dao Lee InstituteShanghai 200240China Collaborative Innovation Center of Extreme Optics Shanxi UniversityTaiyuan 030006China

The accelerometer plays a crucial role in inertial *** performance of conventional accelerometers such as lasers is usually limited by the sensing elements and shot noise limitation(SNL).Here,we propose an advanced development of an accelerometer based on atom–light quantum correlation,which is composed of a cold atomic ensemble,light beams,and an atomic vapor *** cold atomic ensemble,prepared in a magneto-optical trap and free-falling in a vacuum chamber,interacts with light beams to generate atom–light quantum *** atomic vapor cell is used as both a memory element storing the correlated photons emitted from cold atoms and a bandwidth controller through the control of free evolution *** of using a conventional sensing element,the proposed accelerometer employs interference between quantum-correlated atoms and light to measure *** below SNL can be achieved due to atom–light quantum correlation,even in the presence of optical loss and atomic *** can be achieved at the ng∕√Hz level,based on evaluation via practical experimental *** present design has a number of significant advantages over conventional accelerometers such as SNL-broken sensitivity,broad bandwidth from a few hundred Hz to near MHz,and avoidance of the technical restrictions of conventional sensing elements.

关键词： quantum accelerometer atomic

Association between mild or moderate obstructive sleep apnea hypopnea syndrome and cognitive dysfunction in children

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Association between mild or moderate obstructive sleep apnea...

Reducing the mode-mismatch noises in atom–light interactions via optimization of the temporal waveform

中国睡眠研究会第十届全国学术年会

作者： Jing Zhao Shujing Han Jishui Zhang Guixiang wang hua wang zhifei Xu Jun Tai Xiaoxia Peng Yongli Guo Haihong Liu Jinghong Tian Xin Jin Li Zheng Jie Zhang Xin Ni Beijing Key Laboratory for Pediatric Diseases of Otolaryngology Head and Neck SurgeryMOE Key Laboratory of Major Diseases in ChildrenBeijing Pediatric Research InstituteBeijing Children’s HospitalCapital Medical UniversityNational Center for Children's Health (NCCH) Department of Otolaryngology Head and Neck SurgeryBeijing Children’s HospitalCapital Medical UniversityNational Center for Children's Health (NCCH) Department of Neurorehabilitation Beijing Children’s HospitalCapital Medical UniversityNational Center for Children's Health (NCCH) Department of Respiratory Medicine Beijing Children’s HospitalCapital Medical UniversityNational Center for Children's Health (NCCH) Center for Clinical Epidemiology & Evidence-based Medicine Beijing Children’s HospitalCapital Medical UniversityNational Center for Children's Health (NCCH)

Background: Childhood obstructive sleep apnea hypopnea syndrome（OSAHS）,the most common sleep related breathing disorder,may lead to cognitive *** study aims to investigate the association between mild or moderate childhood OSAHS and cognitive ***: A total of 59 children（4-12 years） diagnosed with mild or moderate OSAHS by polysomnography and 60 age-and sex-matched healthy children were included in the *** China-Wechsler Younger Children Scale of Intelligence and China-Wechsler Intelligence Scale for Children were used to evaluate the cognition of the participating children aged ＜6 years and ≥6 years,***: In the subgroup of ＜6-year-old,children with OSAHS had significantly lower scores of full scale IQ（FIQ）,verbal IQ（VIQ）,comprehension test,and visual analysis than the healthy children（All P＜0.05）.In the subgroup of ≥6-year-old,VIQ and classification test scores were significantly lower in children with OSAHS than in the healthy controls（All P＜0.05）.FIQ,VIQ,and performance IQ（PIQ） scores did not correlate with AHI,OAHI,and the lowest nocturnal ***,in the ＜6-year-old subgroup of OSAHS,the accumulated time of SO2＜90%（P=0.046） and the percentage of the accumulated time of SO2＜90% in the total sleep time（P=0.034） correlated with PIQ negatively and ***: Mild to moderate childhood OSAHS may adversely affect cognitive function,particularly in young children（＜6 years of age）.This study may increase the awareness of childhood OSAHS-associated cognitive dysfunction and advocate early interventions in childhood OSAHS.

关键词： Children cognitive function obstructive sleep apnea hypopnea syndrome Wechsler Intelligence Scale for Children

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Photonics Research 2020年第11期8卷 1697-1702页

作者： Xiaotian Feng zhifei Yu Bing Chen Shuying Chen Yuan Wu Donghui Fan Chun-hua Yuan L.Q.Chen Z.Y.Ou Weiping Zhang State Key Laboratory of Precision Spectroscopy Quantum Institute for Light and AtomsDepartment of PhysicsEast China Normal UniversityShanghai 200062China School of Electronic Science and Applied Physics Hefei University of TechnologyHefei 230009China Department of Physics Indiana University-Purdue University IndianapolisIndianapolisIndiana 46202USA School of Physics and Astronomy and Tsung-Dao Lee InstituteShanghai Jiao Tong UniversityShanghai 200240China

Atom–light interface is at the core of quantum metrology and quantum information *** noises during interaction processes are always inevitable and *** this paper,we perform the stimulated Raman scattering(SRS)in a hot Rb 87 vapor cell and demonstrate the reduction of related noises originated from mode mismatch via optimizing the temporal waveform of the input *** using the seed with the optimized mode,the intensity fluctuation of the signal field generated in atom–light interaction is decreased by 4.3 ***,the fluctuation of the intensity difference between the signal and atomic spin wave is reduced by 3.1 *** a temporal mode-cleaning method can be applied to improve the precision of atom interferometry using SRS and should be helpful for quantum information processing based on an atom–light correlated system.

关键词： quantum optimization interferometry

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纳米银及抗菌胶乳的绿色合成

化工新型材料 2021年第6期49卷 253-257页

作者：赵志飞高向华王华魏丽乔太原理工大学新材料界面科学与工程教育部重点实验室太原030024 太原理工大学材料科学与工程学院太原030024

以D-葡萄糖为还原剂,植酸钠(SP)为稳定剂,原位制备出植酸钠-银纳米粒子(SP-AgNPs);将其与天然胶乳(NR)共混,制得抗菌胶乳。采用紫外分光光度计、X射线衍射仪等手段对所制备的样品进行了表征。结果表明:SP具有良好的稳定性作用,制得的纳... 详细信息

以D-葡萄糖为还原剂,植酸钠(SP)为稳定剂,原位制备出植酸钠-银纳米粒子(SP-AgNPs);将其与天然胶乳(NR)共混,制得抗菌胶乳。采用紫外分光光度计、X射线衍射仪等手段对所制备的样品进行了表征。结果表明:SP具有良好的稳定性作用,制得的纳米银(AgNPs)为球形,粒径约为5~12nm;采用大肠杆菌和金黄色葡萄球菌对样品的抗菌性能进行评价,SP-AgNPs具有优异的抗菌性能;改性后的天然胶乳具有良好的抑菌效果,且热稳定性提高。

关键词：植酸钠纳米银胶乳原位抗菌

人肺腺癌TLE1N端Q结构域片段在原核系统表达纯化及其多克隆抗体的制备

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中国肺癌杂志 2010年第11期13卷 1004-1008页

作者：王苏徐志飞唐华魏凌云赵学维第二军医大学附属上海长征医院胸心外科上海200003

背景与目的 TLE1是参与Wnt、Notch以及EGFR信号通路调控的一种重要蛋白。TLE1N端Q结构域片段通过介导自身寡聚化及与LEF1结合发挥调控作用。本实验旨在构建人TLE1N端Q区基因在大肠杆菌的融合表达载体,制备并纯化人TLE1N端Q结构域蛋白片... 详细信息

背景与目的 TLE1是参与Wnt、Notch以及EGFR信号通路调控的一种重要蛋白。TLE1N端Q结构域片段通过介导自身寡聚化及与LEF1结合发挥调控作用。本实验旨在构建人TLE1N端Q区基因在大肠杆菌的融合表达载体,制备并纯化人TLE1N端Q结构域蛋白片段,制备TLE1Q结构域多克隆抗体。方法以人肺腺癌cDNA库为模板聚合酶链反应(polymerase chain reaction,PCR)特异性扩增TLE1-Q(1-136)基因序列,与pGEX-4T-1质粒连接后转化感受态大肠杆菌***。以异丙基-β-D-硫代半乳糖苷(isopropyl-β-D thiogalactoside,IPTG)诱导表达产生融合蛋白GST-TLE1-Q(1-136)。经亲和层析,rombin酶切,FPLC纯化,SDS-PAGE鉴定目的蛋白TLE1-Q(1-136)。免疫家兔,制备多克隆抗体。结果测序证实重组表达质粒中的人TLE1N端Q结构域基因序列正确,成功构建表达型重组质粒pGEX-4T1-TLE1-Q。重组质粒转化大肠杆菌C+后,经诱导,重组蛋白GST-TLE1-Q(1-136)得到表达。SDS-PAGE鉴定示纯化蛋白为目的蛋白人TLE1N端Q结构域片段TLE1-Q(1-136)。免疫家兔后收获抗血清,ELISA显示抗体效价为1:20000,具有高度特异性。免疫印迹结果显示,制备的多抗可与TLE1-Q(1-136)蛋白特异性结合。结论成功构建了人TLE1N端Q结构域重组融合蛋白表达质粒pGEX-4T1-TLE1-Q,表达纯化了稳定可溶TLE1N端Q结构域蛋白TLE1-Q(1-136),制备了人TLE1N端Q结构域蛋白片段多克隆抗体,为进一步研究TLE1在肺癌生成中的作用奠定了基础。

关键词：肺肿瘤 TLE1 基因克隆原核表达蛋白纯化多克隆抗体

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永定河北京段蒸散发研究

地理科学进展 2013年第4期32卷 580-586页

作者：张士锋王翠翠孟秀敬华东门宝辉李智飞中国科学院地理科学与资源研究所北京100101 中国科学院陆地水循环及地表过程重点实验室北京100101 中国科学院大学北京100049 华北电力大学北京102206

永定河北京段蒸散发研究对永定河生态走廊建设有着重要的支撑作用。本文采用多种方法计算了永定河北京段的水面蒸发、潜在蒸散发和实际陆面蒸散发,结果显示:北京段水面蒸发为1182 mm,潜在蒸散发为969mm,1999-2009年北京市实际蒸散发494... 详细信息

永定河北京段蒸散发研究对永定河生态走廊建设有着重要的支撑作用。本文采用多种方法计算了永定河北京段的水面蒸发、潜在蒸散发和实际陆面蒸散发,结果显示:北京段水面蒸发为1182 mm,潜在蒸散发为969mm,1999-2009年北京市实际蒸散发494 mm。对各种水面蒸散发计算结果比较,并通过相关分析和RMSE分析发现,利用中国科学院地理研究所方法计算永定河北京段水面蒸散发较为合理,施成熙方法、前苏联扎依可夫方法计算结果相近,但彭曼公式结果偏大。潜在蒸散发采用Presley-Taylor公式,而联合国粮农组织(FAO)修正的彭曼公式和Hargreaves公式结果都偏大。研究区的实际蒸散量使用傅抱璞方法计算,结果得到了相同研究时段北京市水量平衡研究成果的验证。相比而言,张鲁公式和Turc公式结果偏大,而高桥公式所得结果与傅抱璞方法最为接近。

关键词：蒸散发彭曼公式 Presley-Taylor公式傅抱璞公式永定河

微量鲎试剂动态显色法定量检测重组新型冠状病毒疫苗(CHO细胞)细菌内毒素的研究

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中国药理学通报 2022年第7期38卷 1110-1113页

作者：刘骅王花花王珺宫文武丁震孙备许雷鸣蒲江安徽省食品药品检验研究院安徽合肥230051 安徽智飞龙科马生物制药有限公司安徽合肥230088 安徽省药品监督管理局安徽合肥230051 安徽医科大学第三附属医院安徽合肥230001

目的研究微量动态显色法用于重组新型冠状病毒疫苗(CHO细胞)中细菌内毒素定量检测的可行性。方法使用微量动态显色法鲎试剂,建立细菌内毒素标准曲线,通过干扰预实验确定稀释倍数,测定供试品溶液中外加内毒素的回收率进行干扰试验,完成... 详细信息

目的研究微量动态显色法用于重组新型冠状病毒疫苗(CHO细胞)中细菌内毒素定量检测的可行性。方法使用微量动态显色法鲎试剂,建立细菌内毒素标准曲线,通过干扰预实验确定稀释倍数,测定供试品溶液中外加内毒素的回收率进行干扰试验,完成供试品中细菌内毒素含量的定量检测试验。并与凝胶法试验结果进行比较。结果标准曲线的线性范围为0.02~2.0EU·mL^(-1),回归方程为lgT=-0.3027 lgC+2.8587,r=0.9989,供试品在稀释40倍时均对反应无干扰作用,细菌内毒素回收率在50%~200%范围内,三批供试品的内毒素定量检测结果均符合规定。检测结果与凝胶法一致,符合标准规定。结论微量动态显色法可用于重组新型冠状病毒疫苗(CHO细胞)细菌内毒素定量检测,结果准确,灵敏度高,过程可控。

关键词：重组新型冠状病毒疫苗(CHO细胞) 细菌内毒素检查法微量动态显色法内毒素定量检测凝胶法干扰实验

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Pulse delay of a stimulated Raman process in atomic vapor

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Pulse delay of a stimulated Raman process in atomic vapor