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International Journal of.Minerals,Metallurgy and Materials 2024年第6期31卷 1392-1405页

作者： Liangliang Yuan Mingxing Guo Yi wang Yun wang Linz.ong z.uang Institute of.Ef.ectiveness Evaluation of.f.ying Vehicle Beijing 100085China State Key Laboratory f.r Advanced Metals and Materials University of Science and Technology BeijingBeijing 100083China Beijing Advanced Innovation Center f.r Materials Genome Engineering University of Science and Technology BeijingBeijing 100083China Beijing Laboratory of.Metallic Materials and Processing f.r Modern Transportation University of Science and Technology BeijingBeijing 100083China

This study investigated the inf.uence of.graded z. content on the evolution of.precipitated and iron-rich phases and grain struc-ture of.the alloys,designed and developed the Al–8.0z.–1.5Mg–1.5Cu–0.2f.(wt%)alloy with high strength and *** the increase of.z. content,f.rming the coupling distribution of.multiscale precipitates and iron-rich phases with a reasonable matching ratio and dispersion distribution characteristics is *** phenomenon induces the f.rmation of.cell-like structures with alternate distribu-tion of.coarse and f.ne grains,and the average plasticity–strain ratio(characteriz.ng the f.rmability)of.the pre-aged alloy with a high strength is up to *** reveal the evolution and inf.uence mechanisms of.multiscale second-phase particles and the corresponding high f.rmability mechanism of.the *** developed coupling control process exhibits considerable potential,revealing remarkable improvements in the room temperature f.rmability of.high-strength Al–z.–Mg–Cu alloys.

关键词： Al–z.–Mg–Cu alloy iron-rich phase high f.rmability microstructure mechanisms

Ef.ects of.mesoclimate and microclimate variations mediated by high altitude and row orientation on sucrose metabolism and anthocyanin synthesis in grape berries

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Horticultural Plant Journal 2024年第3期10卷 713-731页

作者： Haining Yin z.aoxiang wang Lin wang Jianhong Cao Jiakui wang z.umei Xi College of.Enology Northwest A&F UniversityYanglingShaanxi 712100China Shangri-la Winery Co. LTDShangri-laYunnan 674400China

Climate change and extreme weather pose signif.cant challenges to the traditional viticulture *** high-altitude grape-producing regions with diverse orientations have shown great potential in coping with this ***,high-quality wine grape production may be achieved by synchroniz.ng the meso-and *** clarif. the role of.high altitude and row orientation in meso-and microclimate and the response of.berries to it,we evaluated seven years(2012-2018)of.climate data,two years of.basic grape(Cabernet Sauvignon,Vitis vinif.ra L.)quality,and one-year microclimate f.om veraison to *** comparing two locations(Sidon 2047 m,Sinon 2208 m)in Yunnan Province,China,we f.und that the average temperature has been stable at approximately 15℃ f.r seven years,with no extreme weather or,noticeable global *** light intensity(LI)in the north-south(NS)was more balanced than the east-west(EW)direction,and the east-west to the south(EW-S)canopy side was almost higher than the other *** LI was associated with high photosynthetically active radiation(PAR),ultraviolet(UV),and inf.ared(IR)light and vice *** north-south to the east(NS-E)and east-west to the north(EWN)sides were characteriz.d by lower LI and higher UV and IR light,and higher total anthocyanin *** anthocyanin synthesis-related genes,f.r example,Vvf.'H and Vvf.'5'H,were highly expressed in NS-E f.om veraison to *** UV and IR light induced their *** study provides new insights on the role of.dif.erently orientated rows in controlling grape quality due to varied light *** f.ndings are globally signif.cant,particularly in the context of.climate change,and of.er f.esh insights into berry physiological responses and decision-making f.r the management of.existing vineyards.

关键词： Vitis vinif.ra L. Orientated rows Berry composition Sugar Phenolic Light quality Solar radiation

Interf.ce catalytic reduction of.alumina by nickle f.r the aluminum nanowire growth: Dynamics observed by in situ TEM

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Nano Research 2024年第3期17卷 1225-1231页

作者： z.chun wang Dan wang Ang Li Liz.uo wang Xiaodong Han Yijiao Jiang Jianf.ng Chen Jun Huang Beijing Advanced Innovation Center f.r Sof. Matter Science and Engineering State Key Laboratory of Organic–Inorganic CompositesBeijing University of Chemical TechnologyBeijing 100029China Laboratory f.r Catalysis Engineering School of Chemical and Biomolecular EngineeringThe University of SydneyNew South Wales 2006Australia Beijing Key Laboratory of.Microstructure and Property of.Advanced Materials Beijing University of TechnologyBeijing 100024China Department of.Engineering Macquarie UniversitySydneyNew South Wales 2109Australia

Metal nanowires show promise in a broad range of.applications and can be f.bricated via a number of.methods,such as vapor–liquid–solid process and template-based ***,the synthesis of.Al nanowires(NWs)is still challenging f.om the stable alumina *** this work,the Ni-catalyz.d f.brication of.Al NWs has been realiz.d using various Al_(2)O_(3) *** growth dynamics of.Al NWs on Ni/Al_(2)O_(3) was studied using in situ transmission electron microscopy(TEM).The ef.ect of.alumina structures,compositions,and growth temperature were *** growth of.Al NWs correlates with the Na addition to the alumina *** no eutectic mixture of.nickel aluminide was f.rmed,a mechanism of.Ni-catalyz.d reduction of.Al_(2)O_(3) f.r Al NWs growth has been proposed instead of.the vapor–liquid–solid *** key insights reported here are not restricted to Ni-catalyz.d Al NWs growth but can be extended to understanding the dynamic change and catalytic perf.rmance of.Ni/Al_(2)O_(3) under working conditions.

关键词： in situ transmission electron microscopy(TEM) Al nanowires alumina reduction nanowire growth

Three dimensional velocity model and its tectonic implications at China Seismic Experimental Site,eastern margin of.the Tibetan Plateau

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Science China Earth Sciences 2024年第7期67卷 2268-2290页

作者： Jianping WU Yan CAI Wei wang Weilai wang Changz.i wang Lihua f.NG Yaning LIU Jing LIU Institute of.Geophysics China Earthquake AdministrationBeijing 100081China Beijing Baijiatuan Earth Science National Observation and Research Station Beijing 1095China Beijing Earthquake Agency Beijing 100080China

The China Seismic Experimental Site(CSES)is located at the intersection of.the Tibetan Plateau,South China Block,and Indian Plate and has complex geological settings and intense crustal def.rmation,making it one of.the most seismically active areas in Chinese mainland.A high-resolution,three-dimensional(3D)crust-mantle velocity structure is crucial f.r understanding seismotectonic environments,lithospheric def.rmation mechanisms,and deep dynamic *** f.rst constructed a high-vertical-resolution 3D initial velocity model using the joint inversion of.receiver f.nctions and surf.ce waves and then obtained a 3D P-and S-wave velocity model(CSES-VM1.0)with the highest lateral resolution of.0.25°f.r the CSES using double-dif.erence *** to the limitations of.the Sn observation data,the resolution of.the S-wave velocity model in the lower crust and upper mantle was reduced,making it closer to the initial model provided by joint inversion.A comparison with explosive-source seismic data showed that the synthetic P-wave f.rst-arrival travel times of.the new model were closer to the observations than those of.the previous velocity *** velocity cross-sections across the source areas of.the 2022 Lushan MS6.1 and Ludian MS6.8 earthquakes reveal that the f.rmer earthquake occurred near a weak contact z.ne between the Tibetan Plateau and Sichuan Basin,and the rupture of.the latter earthquake occurred in a granitic area,with the northern end blocked by rigid high-velocity bodies.A clear high-velocity anomaly z.ne is distributed along the western margin of.the Yangtz. Block,revealing the spatial distribution of.Neoproteroz.ic intermediate-basic *** high-velocity z.ne signif.cantly controls the morphology of.f.ult z.nes and inf.uences the rupture processes of.major *** northeast-southwest and north-south trending high-velocity anomalies were f.und near Panz.ihua,potentially related to Neoproteroz.ic and Middle-Late Permian intermediate

关键词： Eastern Tibetan Plateau China Seismic Experimental Site Yangtz. Block Velocity model Double-dif.erence tomography

Nonconserved epitopes dominate reverse preexisting T cell immunity in COVID-19 convalescents

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Signal Transduction and Targeted Therapy 2024年第7期9卷 2984-2998页

作者： Xin wang Jie z.ang Maoshun Liu Yuanyuan Guo Peipei Guo Xiaonan Yang Bingli Shang Min Li Jinmin Tian Ting z.ang Xi wang Ronghua Jin Jikun z.ou George f.Gao Jun Liu Department of.Epidemiology School of Public HealthCheeloo College of MedicineShandong UniversityJinan 250012China NHC Key Laboratory of.Biosaf.ty Research Unit of Adaptive Evolution and Control of Emerging VirusesChinese Academy of Medical SciencesNational Institute for Viral Disease Control and PreventionChinese Center for Disease Control and Prevention(China CDC)Beijing 102206China Beijing Key Laboratory of.Emerging Inf.ctious Diseases Institute of Infectious DiseasesBeijing Ditan HospitalCapital Medical UniversityBeijing 100015China Beijing Institute of.Inf.ctious Diseases Beijing 100015China National Center f.r Inf.ctious Diseases Beijing Ditan HospitalCapital Medical UniversityBeijing 100015P.R.China School of.Laboratory Medicine and Lif. Sciences Wenzhou Medical UniversityWenzhou 325035China School of.Ophthalmology&Optometry Wenzhou Medical UniversityWenzhou 325027China Collaborative Innovation Centre of.Regenerative Medicine and Medical BioResource Development and Application Co-constructed by the Province and Ministry Guangxi Medical UniversityNanningGuangxi 530021China Shijiaz.uang f.f.h Hospital Shijiazhuang 050011China CAS Key Laboratory of.Pathogen Microbiology and Immunology Institute of MicrobiologyChinese Academy of Sciences(CAS)Beijing 100101China Savaid Medical School University of Chinese Academy of SciencesBeijing 100049China

The herd immunity against SARS-CoV-2 is continuously consolidated across the world during the ongoing ***,the potential f.nction of.the nonconserved epitopes in the reverse preexisting cross-reactivity induced by SARS-CoV-2 to other human coronaviruses is not well *** our research,we assessed T cell responses to both conserved and nonconserved peptides shared by SARS-CoV-2 and SARS-CoV,identif.ing cross-reactive CD8^(+)T cell epitopes using enz.me-linked immunospot and intracellular cytokine staining ***,in vitro ref.lding and circular dichroism were perf.rmed to evaluate the thermal stability of.the HLA/peptide ***,single-cell T cell receptor reservoir was analyz.d based on tetramer ***,we discovered that cross-reactive T cells targeting SARS-CoV were present in individuals who had recovered f.om COVID-19,and identif.ed SARS-CoV-2 CD8^(+)T cell epitopes spanning the major structural antigens.T cell responses induced by the nonconserved peptides between SARS-CoV-2 and SARS-CoV were higher and played a dominant role in the cross-reactivity in COVID-19 ***-T cell reactivity was also observed within the identif.ed series of.CD8^(+)T cell *** representative immunodominant peptide pairs,although the HLA binding capacities f.r peptides f.om SARS-CoV-2 and SARS-CoV were similar,the TCR repertoires recogniz.ng these peptides were *** results could provide benef.cial inf.rmation f.r the development of.peptide-based universal vaccines against coronaviruses.

关键词： immunity conserved assessed

On equivalence of.state-based potential games

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Science China(Inf.rmation Sciences) 2024年第6期67卷 313-327页

作者： Han WU Jinhuan wang Institute of.Mathematics School of ScienceHebei University of Technology

In this paper, we explore state-based potential games using the semi-tensor product of.***, applying the potential equation, we derive both a necessary and suf.icient condition as well as a suf.icient condition to verif. whether a state-based game qualif.es as a potential game. Next, we present two static equivalence conditions of.state-based potential games. We then delve into dynamic equivalence. We propose a criterion that allows us to identif. state-based games that are dynamically equivalent to state-based potential games and share similar dynamic properties. Ultimately, we introduce the concept of.state-based networked evolutionary games. We provide a necessary and suf.icient condition to ensure that a state-based networked evolutionary game can be classif.ed as a state-based potential game.

关键词： semi-tensor product of.matrices state-based potential game verif.cation equivalence state-based networked evolutionary game

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Stimulated Raman scattering tomography f.r rapid three-dimensional chemical imaging of.cells and tissue

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Association of.DNA methylation/demethylation with the f.nctional outcome of.stroke in a hyperinf.ammatory state

Advanced Photonics 2024年第2期6卷 20-31页

作者： Weiqi wang z.iwei Huang National University of.Singapore College of Design and EngineeringOptical Bioimaging LaboratoryDepartment of Biomedical EngineeringSingapore

Three-dimensional(3D)imaging is essential f.r understanding intricate biological and biomedical systems,yet live cell and tissue imaging applications still f.ce challenges due to constrained imaging speed and strong scattering in turbid ***,we present a unique phase-modulated stimulated Raman scattering tomography(PM-SRST)technique to achieve rapid label-f.ee 3D chemical imaging in cells and *** accomplish PM-SRST,we utiliz. a spatial light modulator to electronically manipulate the f.cused Stokes beam along the needle Bessel pump beam f.r SRS tomography without the need f.r mechanical z.*** demonstrate the rapid 3D imaging capability of.PM-SRST by real-time monitoring of.3D Brownian motion of.polystyrene beads in water with 8.5 Hz.volume rate,as well as the instant biochemical responses to acetic acid stimulants in MCf.7 ***,combining the Bessel pump beam with a longer wavelength Stokes beam(NIR-II window)provides a superior scattering resilient ability in PM-SRST,enabling rapid tomography in deeper tissue *** PM-SRST technique providestwof.ld enhancement in imaging depth in highly scattering media(e.g.,polymer beads phantom and biotissue like porcine skin and brain tissue)compared with conventional point-scan *** also demonstrate the rapid 3D imaging ability of.PM-SRST by observing the dynamic dif.usion and uptake processes of.deuterium oxide molecules into plant *** rapid PM-SRST developed can be used to f.cilitate label-f.ee 3D chemical imaging of.metabolic activities and f.nctional dynamic processes of.drug delivery and therapeutics in live cells and tissue.

关键词： stimulated Raman scattering tomography deep tissue Raman imaging spatial light modulation

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Neural Regeneration Research 2024年第10期19卷 2229-2239页

作者： Yubo wang Ling z.ang Tianjie Lyu Lu Cui Shunying z.ao Xuechun wang Meng wang Yongjun wang z.xiao Li Vascular Neurology Department of NeurologyBeijing Tiantan HospitalCapital Medical UniversityBeijingChina China National Clinical Research Center f.r Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina National Center f.r Healthcare Quality Management in Neurological Diseases Beijing Tiantan HospitalCapital Medical UniversityBeijingChina Chinese Institute f.r Brain Research BeijingChina Research Unit of.Artif.cial Intelligence in Cerebrovascular Disease Chinese Academy of Medical SciencesBeijingChina Beijing Engineering Research Center of.Digital Healthcare f.r Neurological Diseases BeijingChina

Inf.ammation is closely related to stroke prognosis, and high inf.ammation status leads to poor f.nctional outcome in stroke. DNA methylation is involved in the pathogenesis and prognosis of.stroke. However, the ef.ect of.DNA methylation on stroke at high levels of.inf.ammation is unclear. In this study, we constructed a hyperinf.ammatory cerebral ischemia mouse model and investigated the ef.ect of.hypomethylation and hypermethylation on the f.nctional outcome. We constructed a mouse model of.transient middle cerebral artery occlusion and treated the mice with lipopolysaccharide to induce a hyperinf.ammatory state. To investigate the ef.ect of.DNA methylation on stroke, we used small molecule inhibitors to restrain the f.nction of.key DNA methylation and demethylation enz.mes. 2,3,5-Triphenyltetraz.lium chloride staining, neurological f.nction scores, neurobehavioral tests, enz.me-linked immunosorbent assay, quantitative reverse transcription PCR and western blot assay were used to evaluate the ef.ects af.er stroke in mice. We assessed changes in the global methylation status by measuring DNA 5-mc and DNA 5-hmc levels in peripheral blood af.er the use of.the inhibitor. In the group treated with the DNA methylation inhibitor, brain tissue 2,3,5-triphenyltetraz.lium chloride staining showed an increase in inf.rct volume, which was accompanied by a decrease in neurological scores and worsening of.neurobehavioral perf.rmance. The levels of.inf.ammatory f.ctors interleukin 6 and interleukin-1 beta in ischemic brain tissue and plasma were elevated, indicating increased inf.ammation. Related inf.ammatory pathway exploration showed signif.cant overactivation of.nuclear f.ctor kappa B. These results suggested that inhibiting DNA methylation led to poor f.nctional outcome in mice with high inf.ammation f.llowing stroke. f.rther, the ef.ects were reversed by inhibition of.DNA demethylation. Our f.ndings suggest that DNA methylation regulates the inf.ammatory response in stroke

关键词： DNA demethylation DNA methylation DNMT3A f.nctional outcome hyperinf.ammatory state interleukin neuroinf.ammation stroke TET2

Multi-granularity sequence generation f.r hierarchical image classif.cation

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Computational Visual Media 2024年第2期10卷 243-260页

作者： Xinda Liu Lili wang State Key Laboratory of.Virtual Reality Technology and Systems Beihang UniversityBeijing 100191China Peng Cheng Laboratory Shengzhen 518000China

Hierarchical multi-granularity image classif.cation is a challenging task that aims to tag each given image with multiple granularity labels *** methods tend to overlook that dif.erent image regions contribute dif.erently to label prediction at dif.erent granularities,and also insuf.iciently consider relationships between the hierarchical multi-granularity *** introduce a sequence-to-sequence mechanism to overcome these two problems and propose a multi-granularity sequence generation(MGSG)approach f.r the hierarchical multi-granularity image classif.cation ***,we introduce a transf.rmer architecture to encode the image into visual representation ***,we traverse the taxonomic tree and organiz. the multi-granularity labels into sequences,and vectoriz. them and add positional *** proposed multi-granularity sequence generation method builds a decoder that takes visual representation sequences and semantic label embedding as inputs,and outputs the predicted multi-granularity label *** decoder models dependencies and correlations between multi-granularity labels through a masked multi-head self.attention mechanism,and relates visual inf.rmation to the semantic label inf.rmation through a crossmodality attention *** this way,the proposed method preserves the relationships between labels at dif.erent granularity levels and takes into account the inf.uence of.dif.erent image regions on labels with dif.erent *** on six public benchmarks qualitatively and quantitatively demonstrate the advantages of.the proposed *** project is available at https://***/liuxindaz./mgs.

关键词： hierarchical multi-granularity classif.cation vision and text transf.rmer sequence generation f.ne-grained image recognition cross-modality attenti

Oxide-supported metal catalysts f.r anaerobic NAD+regeneration with concurrent hydrogen production

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Chinese Chemical Letters 2024年第2期35卷 263-267页

作者： Jianwei Li Joseph W.H.Burnett Claudia Martinez.Macias Russell f.Howe Xiaodong wang Chemical Engineering School of EngineeringLancaster UniversityLancaster LA1 4YWUnited Kingdom Chemistry Department University of AberdeenAberdeen AB24 3UEUnited Kingdom

We report SiO_(2)-supported monometallic Pt,Pd,Au,Ni,Cu and Co catalysts f.r proton-driven NAD+regeneration,co-producing H_(2).All metals are f.lly selective to NAD+where the order of.turnover f.equencies(Pt>Pd>Cu>Au,Ni and Co)coincides with those otherwise observed in electrochemical hydrogen evolution *** has revealed that NADH is capable of.converting the metal sites into a“cathode”without an external potential and the NADH to NAD+reaction involves transf.rring electron and hydrogen atom ***-def.cient Ptδ+(on CeO_(2))enhances TOf.and the heterogeneous Pt/CeO_(2) catalyst is recyclable without losing any activity/selectivity.

关键词： NAD+regeneration Heterogeneous catalyst Hydrogenase mimic Hydrogen binding energy Hydrogen production