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Treatment of hepatitis B virus-associated glomerulonephritis:A meta-analysis

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World Journal of Gastroenterology 2010年第6期16卷 770-777页

作者： Zhang, yu Zhou, Jian-Hua Yin, Xiao-Ling wang, feng-yu Huazhong Univ Sci & Technol Dept Pediat Tongji Hosp Tongji Med Coll Wuhan 430030 Hubei Province Peoples R China

AIM:To evaluate the efficacy of antiviral or corticosteroid treatment on hepatitis B virus-associated glomerulonephritis(HBV-GN) . METHODS:Six and five trials were used respectively to evaluate the efficacy of either antiviral or corticosteroid treatment on *** patients were pooled separately to assess their response to the above treatment *** primary and secondary outcomes were remission of proteinuria and clearance of Hepatitis B e-antigen(HBeAg) ,respectively.A fixed or random effect model was established to collect the data. RESULTS:The remission rate of proteinuria(RR=1.69,95%CI:1.08-2.65) and the clearance rate of HBeAg(RR =6.44,95%CI:3.11-13.35) were significantly higher in antiviral treatment group than in control *** proteinuria remission was significantly associated with HBeAg clearance(P=0.002) .However,the difference in proteinuria remission rate was not statistically significant between corticosteroid treatment group and controlgroup(RR=1.45,95%CI:0.68-3.11) .Antiviral therapy could significantly promote the HBeAg clearance in pediatric patients,but neither antiviral nor corticosteroid therapy could significantly decrease proteinuria in pediatric patients compared to controls. CONCLUSION:Antiviral but not corticosteroid treatment can decrease proteinuria and promote HBeAg clearance in HBV-GN patients.

关键词： Hepatitis B virus-associated glomerulonephritis Drug therapy Meta-analysis

A series of carbosilane dendrimers with acetyl end-group:From synthesis to their unique optical characteristics

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Chinese Chemical Letters 2009年第9期20卷 1085-1087页

作者： Wen Yan Sun Hai feng Lu Deng Xu wang Sheng yu feng School of Chemistry and Chemical Engineering Shandong University Ji'nan 250100 China

A series of c arbosilane dendrimers with acetyl end-group were synthesized. Their structures were characterized by 1H NMR, IR, and MS, respectively. Then dendrimers were coordinated with lanthanide ions （Eu3＋ and Tb3＋, respectively）. The luminescence spectra of the complexes show narrow-width emissions in visible light region. 2009 Sheng yu feng. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.

关键词： Synthesis Carbosilane dendrirner Luminescence Lanthanide ions

Synthesis of carbosilane dendrimers with N,N-dimethylaniline as end groups

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Chinese Chemical Letters 2009年第3期20卷 300-301页

作者： Wen Yan Sun Deng Xu wang Sheng yu feng School of Chemistry and Chemical Engineering Shandong University Ji'nan 250100 China

Carbosilane dendrimers with 4-bromo-N,N-dimethylaniline as end groups were synthesized from methyltfichlorosilane, aUyl chloride, magnesium and 4-bromo-N,N-dimethylaniline. All compounds were characterized by ^1H NMR,... 详细信息

关键词： Dendrimer Synthesis Carbosilane

Thermal hydraulic and mechanical analysis of CH HCSB TBM

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核聚变与等离子体物理 2006年第3期26卷 181-185页

作者： wang Xiao-yu feng Kai-ming ZHANG Guo-shu yuAN Tao Southwestern Institute of Physics Chengdu 610041

Based on the structure design and results of neutronics analysis of the CH HCSB TBM (Chinese helium cooled solid breeder test blanket module), thermal hydraulic and mechanical analyses have been carried out. Results s... 详细信息

关键词：热水力分析中子物理学分析再生区热核反应

Research on hybrid power filter of 6 kV power grid in coal mine

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Journal of Coal Science & Engineering(China) 2010年第4期16卷 434-440页

作者： wang yu-feng LI Jian Faculty of Electrical and Control Engineering Liaoning Technical University Huludao 125105 China

Studied the harmonic control of the 6 kV power grid in a coal mine *** harmonic suppression and reactive power compensation into account, and complyingwith the economic and efficient technical line of the smart grid, a new hybrid activefilter was proposed and applied to the power grid in the coal mine with the advantagessuch as large capacity, low cost and low *** order to improve detection speed and reducethe succeeding errors to improve the filtering performance of the active power filter,the DFT (Discrete Fourier Transform) sliding window algorithm based on coordinatetransformation and improved hysteresis control method was *** Matlab simulationresults show that the hybrid active filter is satisfactory, can improve the grid powerfactor and can meet the requirements of improving the power quality in the coal mine.

关键词： Hybrid power filter DFT hysteresis control method Matlab

Glucose,cellobiose,lactose and raffinose used as chiral stationary phases in HPLC

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Chinese Chemical Letters 2008年第10期19卷 1248-1251页

作者： Jian yu wang feng Zhao Mei Zhang Ya Peng Li Ming yuan Department of Chemistry Yunnan Normal University Kunming 650092 China

This paper presents the enantioseparation using glucose, cellobiose, lactose and raffinose as chiral selector bonded to silica gel via an arm in HPLC. Surprisingly, they also possess high enantioseparation selectivity, may be used in normal-phase and reversed- phase mode, and there is a big chiral discriminating complementary. This work indicates that oligosaccharides could soon become very attractive as a new class of chiral stationary phase for HPLC.

关键词： Oligosaccharides Chiral stationary phase HPLC

In vitro pancreas duodenal homeobox-1 enhances the differentiation of pancreatic ductal epithelial cells into insulin-producing cells

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World Journal of Gastroenterology 2007年第39期13卷 5232-5237页

作者： Tao Liu Chun-You wang feng yu Shan-Miao Gou He-Shui Wu Jiong-Xin Xiong feng Zhou Department of Pancreatic Surgery Union Hospital Tongji Medical College Huazhong University of Science and Technology Wuhan 430022 Hubei Province China

AIM: To observe whether pancreatic and duodenal homeobox factor-1 enhances the differentiation of pancreatic ductal epithelial cells into insulin-producing cells in vitro. METHODS: Rat pancreatic tissue was submitted to digestion by collegenase, ductal epithelial cells were separated by density gradient centrifugation and then cultured in RPMI1640 medium with 10% fetal bovine serum. After 3-5 passages, the cells were incubated in a six-well plate for 24 h before transfection of recombination plasmid XlHbox8VP16. Lightcycler quantitative real-time RT-PCR was used to detect the expression of PDX-1 and insulin mRNA in pancreatic epithelial cells. The expression of PDX-1 and insulin protein was analyzed by Western blotting. Insulin secretion was detected by radioimmunoassay. Insulin- producing cells were detected by dithizone-staining. RESULTS: XlHbox8 mRNA was expressed in pancreatic ductal epithelial cells. PDX-1 and insulin mRNA as well as PDX-1 and insulin protein were signifi cantly increased in the transfected group. The production and insulin secretion of insulin-producing cells differentiated from pancreatic ductal epithelial cells were higher than those of the untransfected cells in vitro with a significant difference (1.32 ± 0.43 vs 3.48 ± 0.81, P < 0.01 at 5.6 mmol/L; 4.86 ± 1.15 vs 10.25 ± 1.32, P < 0.01 at 16.7 mmol/L). CONCLUSION: PDX-1 can differentiate rat pancreaticductal epithelial cells into insulin-producing cells in vitro. In vitro PDX-1 transfection is a valuable strategy for increasing the source of insulin-producing cells.

关键词： Pancreatic ductal epithelial cells Islet Differentiation Pancreas duodenal homeobox-i

Formation mechanism of micro-flows in aqueous poly(ethylene oxide) droplets on a substrate at different temperatures

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Petroleum Science 2013年第2期10卷 262-268页

作者： Hu Yin-Chun Zhou Qiong wang yu-feng Song yun-Yang Cui Li-Shan Department of Material Science and Engineering College of ScienceChina University of Petroleum(Beijing)

The drying of aqueous poly（ethylene oxide）（PEO） droplet on a substrate at different temperatures was studied. It was found that the contact line receded when the substrate was at a temperature above 60 ℃. Different nucleation behavior and surface profiles of PEO films were found in different droplets drying processes. The rheological properties of aqueous PEO solutions were studied to understand the mechanism of contact line recession and micro-flow in drying aqueous PEO droplets. It was found that at low temperature, the contact line was static because of great viscous stress; while at high temperature, it receded because of great Marangoni force and the decrease of viscous stress. It was indicated that Marangoni convection was inhibited by the outward capillary flow and viscous stress at low temperature, whereas it became dominant at high temperature. Two types of mechanism for surface profiles and nucleation of PEO film from drying droplets are proposed, providing a theoretical guide for polymer solution application in oil and gas foam flooding technology.

关键词： Poly(ethylene oxide), droplet micro-flow, nucleation, surface profile

Simulation research of discrete sliding mode control for active power filter

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Journal of Coal Science & Engineering(China) 2011年第4期17卷 461-463页

作者： wang yu-feng SUN Bao YANG Zhen LI Jian Faculty of Electrical and Control Engineering Liaoning Technical University Huludao 125105 China

Because of the widely-used nonlinear loads, the problems of harmonics and low power factor in power systems are becoming more and more serious. In view of the above problems, a shunt three-phase active power filter （SAPF） based on discrete sliding mode control to suppress the harmonics was designed and the power factor improved. First, built the mathematical model of SAPF. Then, controlled the switch through analyzing the harmonic current that was controlled signal using discrete sliding mode control. Through simulation using MATLAB, verified the validity of the algorithm. By the simulation waveforms, it can be found that after the load current containing a large number of harmonics passes the active power filter, the waveform of the power current approximately becomes a sine wave and the harmonics is significantly reduced. As a result, it plays a good role in purifying power systems. Moreover, from the waveforms of harmonic current and power current, it can be found that the algorithm has a faster tracking speed. The waveform can fect.

关键词： discrete sliding mode control be stably tracked in the half cycle and real-time if the algorithm is perpower electronics shunt active power filter