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Glucose,cellobiose,lactose and raffinose used as chiral stationary phases in HPLC

Glucose,cellobiose,lactose and raffinose used as chiral stationary phases in HPLC

作     者:Jian Yu Wang Feng Zhao Mei Zhang Ya Peng Li Ming Yuan 

作者机构:Department of Chemistry Yunnan Normal University Kunming 650092 China 

出 版 物:《Chinese Chemical Letters》 (中国化学快报(英文版))

年 卷 期:2008年第19卷第10期

页      面:1248-1251页

核心收录:

学科分类:0710[理学-生物学] 071010[理学-生物化学与分子生物学] 081704[工学-应用化学] 07[理学] 08[工学] 0817[工学-化学工程与技术] 

基  金:National Natural Science Foundation and Yunnan Province's Natural Science Foundation of China(No.20775066No.2005E0006Z) 

主  题:Oligosaccharides Chiral stationary phase HPLC 

摘      要:This paper presents the enantioseparation using glucose, cellobiose, lactose and raffinose as chiral selector bonded to silica gel via an arm in HPLC. Surprisingly, they also possess high enantioseparation selectivity, may be used in normal-phase and reversed- phase mode, and there is a big chiral discriminating complementary. This work indicates that oligosaccharides could soon become very attractive as a new class of chiral stationary phase for HPLC.

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