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The reason for the amelioration of N-methyl-N-nitrosourea-induced retinitis pigmentosa in rats by hydrogen-rich saline

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International Journal of Ophthalmology(English edition) 2017年第10期10卷 1495-1503页

作者： wei-ming yan Tao Chen xiao-Cheng wang Lin-Song Qi Guan-Hua zhao Guo-qing yang Yi-Fei Ma Ye Tao Lei zhang Zuo-ming zhang Department of Clinical Medicine Faculty of Aerospace MedicineKey Laboratory of Aerospace Medicine of the National Education Ministrythe Fourth Military Medical University Department of Health Service Faculty of Aerospacethe Fourth Military Medical University Department of Aviation Physical Examination and Ophthalmology Air Force General Hospital Department of Ophthalmology General Hospital of Chinese PLAOphthalmology &Visual Science Key Lab of PLA

AIM：To investigate the effects of hydrogen-rich saline（HRS）on microglia activation and Sirtuin type 1（Sirt1）in rats with N-methyl-N-nitrosourea（MNU）-induced retinitis pigmentosa（RP）.METHODS：Rats were divided into norm（N）group,model（M）group and HRS（H）*** in M and H groups were given saline and HRS respectively prior to and after administration of *** one day（d1）and d3 afterwards,electroretinogram and histological examination were performed to confirm the effects of HRS on retinal function and structure of MNU-induced *** staining of anti-ionized calcium-binding adapter molecule 1（Iba1）,a maker of microglia cells,was performed,with quantitative real-time polymerase chain reaction（qRT-PCR）for its m RNA ***,Sirt1 m RNA and protein expression in the retinas were detected by Western blot and ***：HRS preserved the retinal function and mitigated the reduction of photoreceptor degeneration in MNU-treated *** presence of microglia cells was somewhat more obvious in H group than that in M group at *** suppressed the further activation of microglia cells,with the number of microglia cells less than that of M group at *** of qRT-PCR of Iba1 were consistent with those of immunofluorescence staining,with the m RNA expression of Iba1 in H group more intensive than that of M group at d1（P〈0.05）,while less than that of M group at d3（P〈0.05）.Furthermore,the Sirt1 m RNA and protein expression decreased after MNU administration,while HRS mitigated the MNU-induced downregulation of ***：HRS can effectively keep microglia activation induced by MNU to an appropriate extent,while upregulate Sirt1 in MNU-induced RP.

关键词： hydrogen hydrogen-rich saline electroretinogram microglia Sirtl retinitis pigmentosa

Onset and Recurrence Characteristics of Chinese Patients with Noncardiogenic Ischemic Stroke in Chinese Medicine Hospitals

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Chinese Journal of Integrative Medicine 2022年第6期28卷 492-500页

作者： GAO yang XIE yan-ming wang Gui-qian CAI Ye-feng SHEN xiao-ming zhao De-xi XIE Ying-zhen zhang Yin MENG Fan-xing YU Hai-qing JIANG Jun-jie wei Rui-Li Institute of Basic Research in Clinical Medicine China Academy of Chinese Medical SciencesBeijing100700China Department of Rehabilitation Dongfang HospitalBeijing University of Chinese MedicineBeijing100078China Department of Emergency Beijing Hospital of Traditional Chinese MedicineCapital Medical UniversityBeijing100010China Department of Neurology Guangdong Provincial Hospital of Chinese MedicineGuangzhou510120China Department of Neurology the First Affiliated Hospital of Henan University of Chinese MedicineZhengzhou450000China Department of Neurology the Affiliated Hospital of Changchun University of Chinese MedicineChangchun130017China Department of Neurology Dongzhimen HospitalBeijing University of Chinese MedicineBeijing100700China Department of Neurology Taiyuan Hospital of Traditional Chinese MedicineTaiyuan140107China

Objective:To delineate the onset and recurrence characteristics of noncardiogenic ischemic stroke patients in ***:A prospective,multicenter and registry study was carried out in 2,558 patients at 7 representative clinical sub-centers during November 3,2016 to February 17,2019.A questionnaire was used to collect information of patients regarding CM syndromes and constitutions and associated risk ***,stroke recurrence was defined as a primary outcome ***:A total of 327(12.78%)patients endured recurrence events,1,681(65.72%)patients were men,and the average age was 63.33±9.45 *** 1,741(68.06%)patients suffered first-ever ischemic stroke,1,772(69.27%)patients reported to have hypertension,and1,640(64.11%)of them reported dyslipidemia,1,595(62.35%)patients exhibited small-artery occlusion by The Trial of Org 10172 in Acute Stroke Treatment(TOAST)***,1,271(49.69%)patients were considered as qi-deficient constitution,and 1,227(47.97%)patients were determined as stagnant blood *** were 1,303(50.94%)patients diagnosed as blood stasis syndrome,1,280(50.04%)patients exhibited phlegm and dampness syndrome and 1,012(39.56%)patients demonstrated qi deficiency *** 1,033(40.38%)patients declared intracranial artery stenosis,and 478(18.69%)patients reported carotid artery *** plaque in 1,508(41.36%)patients were of ***,41.09%of them demonstrated abnormal levels of glycated hemoglobin(HbA1 c)***:Recurrence in minor and small-artery stroke cannot be ***,dyslipidemia,abnormal HbA1 c,intracranial artery stenosis and carotid plaque were more common in stroke ***,phlegm-dampness and blood stasis syndromes,as well as qi deficiency and blood stasis constitutions,were still the main manifestations of stroke.(Trial registration at ***,***03174535)

关键词： noncardiogenic ischemic stroke Chinese medicine hospital onset characteristics recurrence

Characterization of chromosome segment substitution lines reveals candidate genes associated with the nodule number in soybean

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Journal of Integrative Agriculture 2022年第8期21卷 2197-2210页

作者： ZOU Jia-nan zhang Zhan-guo KANG qing-lin YU Si-yang wang Jie-qi CHEN Lin LIU yan-ru MA Chao ZHU Rong-sheng ZHU Yong-xu DONG xiao-hui JIANG Hong-wei WU xiao-xia wang Nan-nan HU Zhen-bang QI zhao-ming LIU Chun-yan CHEN qing-shan XIN Da-wei wang Jin-hui College of Agriculture Northeast Agricultural UniversityHarbin 150030P.R.China Suihua Branch of Heilongjiang Academy of Agricultural Sciences Suihua 152000P.R.China Soybean Research Institute Jilin Academy of Agricultural SciencesChangchun 130033P.R.China Jiamusi Branch of Heilongjiang Academy of Agricultural Sciences Jiamusi 154000P.R.China

Soybean is one of the most important food crops *** other legumes,soybean can form symbiotic relationships with Rhizobium *** fixation of soybean via its symbiosis with Rhizobium is pivotal for sustainable *** Ⅲ effectors(T3Es)are essential regulators of the establishment of the symbiosis,and nodule number is a feature of nitrogen-affected ***,genes encoding T3Es at quantitative trait loci(QTLs)related to nodulation have rarely been *** segment substitution lines(CSSLs)have a common genetic background but only a few loci with heterogeneous genetic information;thus,they are suitable materials for identifying candidate genes at a target *** this study,a CSSL population was used to identify the QTLs related to nodule number in *** nucleotide polymorphism(SNP)markers and candidate genes within the QTLs interval were detected,and it was determined which genes showed differential expression between *** candidate genes(GmCDPK28,GmNAC1,GmbHLH,and GmERF5)linked to the SNPs were identified as being related to nodule traits and pivotal processes and pathways involved in symbiosis establishment.A candidate gene(GmERF5)encoding a transcription factor that may interact directly with the T3E NopAA was *** confirmed CSSLs with important segments and candidate genes identified in this study are valuable resources for further studies on the genetic network and T3Es involved in the signaling pathway that is essential for symbiosis establishment.

关键词： soybean TypeⅢeffectors nodule number chromosome segment substitution lines

Optimized online filter stack spectrometer for ultrashort X-ray pulses

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Nuclear Science and Techniques 2024年第5期35卷 85-98页

作者： Jia-Xing Wen Ge Ma ming-Hai Yu Yu-Chi Wu Yong-Hong yan Shao-Yi wang Huai-Zhong Gao Lu-Shan wang Yu-Gang Zhou Qiang Li Yue yang Fang Tan xiao-Hui zhang Jie zhang Wen-Bo Mo Jing-Qin Su wei-Min Zhou Yu-Qiu Gu ming Zeng Zong-qing zhao Science and Technology on Plasma Physics Laboratory Laser Fusion Research CenterCAEPMianyang 621900China Department of Engineering Physics Tsinghua UniversityBeijing 100084China Key Laboratory of Particle and Radiation Imaging(Tsinghua University) Ministry of EducationBeijing 100084China School of Information Engineering Southwest University of Science and TechnologyMianyang 621010China

Currently,with the advent of high-repetition-rate laser-plasma experiments,the demand for online diagnosis for the X-ray spectrum is increasing because the laser-plasma-generated X-ray spectrum is very important for characterizing electron dynamics and *** this study,scintillators and silicon PIN(P-type–intrinsic-N-type semiconductor)diodes were used to construct a wideband online filter stack *** X-ray sensor and filter arrangement was optimized using a genetic algorithm to minimize the condition number of the response ***,the unfolding error was significantly reduced based on numerical *** detector responses were quantitatively calibrated by irradiating the scintillator and PIN diode with various nuclides and comparing the measuredγ-ray peaks.A prototype 15-channel spectrometer was developed by integrating an X-ray detector with front-and back-end *** prototype spectrometer could record X-ray pulse signals at a repetition rate of 1 ***,an optimized spectrometer was employed to record the real-time spectra of laser-driven bremsstrahlung *** optimized spectrometer offers a compact solution for spectrum diagnostics of ultrashort X-ray pulses,exhibiting improved accuracy in terms of spectrum measurements and repetition rates,and could be widely used in next-generation high-repetition-rate high-power laser facilities.

关键词： Filter stack spectrometer Laser plasma diagnostics X-ray diagnostics Scintillator PIN diode

Erlotinib versus gemcitabine plus cisplatin as neoadjuvant treatment of stage IIIA-N2 EGFR-mutant non-small-cell lung cancer:final overall survival analysis of the EMERGING-CTONG 1103 randomised phase II trial

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Signal Transduction and Targeted Therapy 2023年第3期8卷 1310-1317页

作者： Wen-zhao Zhong Hong-Hong yan Ke-Neng Chen Chun Chen Chun-Dong Gu Jun wang Xue-Ning yang wei-Min Mao Qun wang Gui-Bin Qiao Ying Cheng Lin Xu Chang-Li wang ming-wei Chen xiao-Zheng Kang Wan-Pu yan Ri-Qiang Liao Jin-Ji yang Xu-Chao zhang Si-yang Liu qing Zhou Yi-Long Wu Guangdong Provincial People’s Hospital Guangdong Academy of Medical Sciences510080 GuangzhouChina Peking University Cancer Hospital and Institute 100142 BeijingChina Fujian Medical University Union Hospital 350001 FuzhouChina First Affiliated Hospital of Dalian Medical University 116011 DalianChina Peking University People’s Hospital 100044 BeijingChina Zhejiang Cancer Hospital 310022 HangzhouChina Zhongshan Hospital 200032 ShanghaiChina Guangzhou Liuhuaqiao Hospital 510000 GuangzhouChina Jilin Provincial Tumor Hospital 130012 ChangchunChina Jiangsu Cancer Institute and Hospital 210009 NanjingChina Tianjin Medical University Cancer Institute and Hospital 300060 TianjinChina First Affiliated Hospital of Xi’an Jiaotong University 710061 Xi’anChina

EMERGING-CTONG 1103 showed improved progression-free survival(PFS)with neoadjuvant erlotinib *** for patients harbouring EGFR sensibility mutations and R0 resected stage IIIA-N2 non-small cell lung cancer(NSCLC)(NCT01407822).Herein,we report the final *** patients were randomly allocated 1:1 to the erlotinib group(150 mg/day orally;neoadjuvant phase for 42 days and adjuvant phase to 12 months)or to the GC group(gemcitabine 1250 mg/m2 plus cisplatin 75 mg/m2 intravenously;2 cycles in neoadjuvant phase and 2 cycles in adjuvant phase).Objective response rate(ORR),complete pathologic response(pCR),PFS,and overall survival(OS)were assessed along with *** hoc analysis was performed for subsequent treatments after disease *** investigated 72 patients(erlotinib,n=37;GC,n=35),the median follow-up was 62.5 *** median OS was 42.2 months(erlotinib)and 36.9 months(GC)(hazard ratio[HR],0.83;95%confidence interval[CI],0.47-1.47;p=0.513).The 3-and_(5-y)ear OS rates were 58.6%and 40.8%with erlotinib and 55.9%and 27.6%with GC(p_(3-y)=0.819,p_(5-y)=0.252).Subsequent treatment was administered in 71.9%and 81.8%of patients receiving erlotinib and GC,respectively;targeted therapy contributed mostly to OS(HR,0.35;95%CI,0.18-0.70).After disease progression,the ORR was 53.3%,and the median PFS was 10.9 months during the EGFR-TKI *** postoperative therapy,grade 3 or 4 adverse events(AEs)were 13.5%in the erlotinib group and 29.4%in the GC *** serious adverse events were *** exhibited clinical feasibility for resectable IIIA-N2 NSCLC over chemotherapy in the neoadjuvant setting.

关键词： neoadjuvant cisplatin chemotherapy

Systematic evaluation of IgG responses to SARS-CoV-2 spike protein-derived peptides for monitoring COVID-19 patients

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Cellular & Molecular Immunology 2021年第3期18卷 621-631页

作者： yang Li Dan-yun La qing Lei zhao-wei Xu Feng wang Hongyan Hou Lingyun Chen Jiaoxiang Wu yan Ren ming-liang Ma Bo zhang Hong Chen Caizheng Yu Jun-biao Xue Yun-xiao Zheng Xue-ning wang He-wei Jiang Hai-nan zhang Huan Qi Shu-juan Guo yandi zhang xiaosong Lin Zongjie Yao Pengfei Pang Dawei Shi wei wang xiao yang Jie Zhou Huiming Sheng Ziyong Sun Hong Shan Xionglin Fan Sheng-ce Tao Shanghai Center for Systems Biomedicine Key Laboratory of Systems Biomedicine(Ministry of Education)Shanghai Jiao Tong UniversityShanghaiChina Department of Pathogen Biology School of Basic MedicineTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Key Laboratory of Gastrointestinal Cancer(Fujian Medical University) Ministry of EducationSchool of Basic Medical SciencesFujian Medical UniversityFuzhouChina Department of Clinical Laboratory Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina SBGI Education Center University of Chinese Academy of SciencesShenzhen 518083China Tongren Hospital Shanghai Jiao Tong University School of MedicineShanghaiChina BGI-Shenzhenf Shenzhen 518083 China Department of Public Health Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhanChina Center for Interventional Medicine The Fifth Affiliated Hospital of Sun Yat-sen UniversityZhuhai 519000China National Institutes for Food and Drug Control Beijing 100050China Foshan Fourth Peopled Hospital Foshan 528000China Key Laboratory of RNA Biology Institute of BiophysicsChinese Academy of SciencesBeijing 100101China

Serological tests play an essential role in monitoring and combating the COVID-19 *** spike protein(S protein),especially the S1 protein,is one of the major reagents used for serological ***,the high cost of S protein production and possible cross-reactivity with other human coronaviruses pose unavoidable *** taking advantage of a peptide microarray with full spike protein coverage,we analyzed 2,434 sera from 858 COVID-19 patients,63 asymptomatic patients and 610 controls collected from multiple clinical *** on the results,we identified several S protein-derived 12-mer peptides that have high diagnostic *** particular,for monitoring the IgG response,one peptide(aa 1148-1159 or S2-78)exhibited a sensitivity(95.5%,95%CI 93.7-96.9%)and specificity(96.7%,95%CI 94.8-98.0%)comparable to those of the S1 protein for the detection of both symptomatic and asymptomatic COVID-19 ***,the diagnostic performance of the S2-78(aa 1148-1159)IgG was successfully validated by ELISA in an independent sample cohort.A panel of four peptides,S1-93(aa 553-564),S1-97(aa 577-588),S1-101(aa 601-612)and S1-105(aa 625-636),that likely will avoid potential cross-reactivity with sera from patients infected by other coronaviruses was *** peptides identified in this study may be applied independently or in combination with the S1 protein for accurate,affordable,and accessible COVID-19 diagnosis.

关键词： SARS-CoV-2 Spike peptide Antibody Diagnosis

Frontiers in high entropy alloys and high entropy functional materials

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Rare Metals 2024年第10期43卷 4639-4776页

作者： Wen-Tao zhang Xue-Qian wang Feng-Qi zhang xiao-Ya Cui Bing-Bing Fan Jia-ming Guo Zhi-Min Guo Rui Huang Wen Huang Xu-Bo Li Meng-Ru Li yan Ma Zhi-Hua Shen Yong-Gang Sun De-Zhuang wang Fei-yang wang Li-Qiang wang Nan wang Tian-Li wang wei wang xiao-yang wang Yi-Han wang Fu-Jie Yu Yu-Zhen Yin Ling-Kun zhang Yi zhang Jian-yang zhang Qi zhao Yu-Ping zhao Xin-Dong Zhu Yasir Sohail Ya-Nan Chen Tao Feng Qi-Long Gao Hai-yan He Yong-Jiang Huang Zeng-Bao Jiao Hua Ji Yao Jiang Qiang Li xiao-ming Li wei-Bing Liao Huai-Jun Lin Hui Liu Qi Liu qing-Feng Liu wei-Di Liu Xiong-Jun Liu yang Lu Yi-Ping Lu Wen Ma Xue-Fei Miao Jie Pan qing wang Hong-Hui Wu Yuan Wu Tao yang wei-ming yang Qian Yu Jin-Yu zhang Zhi-Gang Chen Liang Mao yang Ren Bao-Long Shen Xun-Li wang Zhe Jia He Zhu Zhen-Duo Wu Si Lan School of Materials Science and Engineering Nanjing University of Science and TechnologyNanjing 210094China Jiangsu Key Laboratory for Advanced Metallic Materials School of Materials Science and EngineeringSoutheast UniversityNanjing 211189China Department of Physics City University of Hong KongHongKong 999077China School of Materials Science and Engineering Tianjin UniversityTianjin 300072China School of Physics and Microelectronics Zhengzhou UniversityZhengzhou 450001China Department of Mechanical Engineering Research Institute for Advanced ManufacturingThe Hong Kong Polytechnic UniversityHong Kong 100872China Center of Electron Microscopy and State Key Laboratory of Silicon Materials School of Materials Science and EngineeringZhejiang UniversityHangzhou 310027China Key Laboratory of Solidification Control and Digital Preparation Technology(Liaoning Province) School of Materials Science and EngineeringDalian University of TechnologyDalian 116024China Institute of Advanced Wear&Corrosion Resistance and Functional Materials Jinan UniversityGuangzhou 510632China School of Mechanics and Civil Engineering China University of Mining and TechnologyXuzhou 221116China School of Physical Sciences Great Bay UniversityDongguan 523000China School of Materials Science and Engineering Harbin Institute of TechnologyHarbin 150001China State Key Laboratory of Materials-Oriented Chemical Engineering College of Chemical EngineeringNanjing Tech UniversityNanjing 211816China Beijing Advanced Innovation Center for Materials Genome Engineering Research Institute for Carbon NeutralityUniversity of Science and Technology BeijingBeijing 100083China Department of Mechanical Engineering The University of Hong KongHong Kong 999077China School of Computing Macquarie UniversitySydney 2113Australia Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060China State Key Laborato

Owing to their exceptional properties,high-entropy alloys(HEAs)and high-entropy materials have emerged as promising research areas and shown diverse ***,the recent advances in the field are comprehensively reviewed,organized into five *** first section introduces the background of HEAs,covering their definition,significance,application prospects,basic properties,design principles,and *** subsequent section focuses on cutting-edge high-entropy structural materials,highlighting developments such as nanostructured alloys,grain boundary engineering,eutectic systems,cryogenic alloys,thin films,micro-nano-lattice structures,additive manufacturing,high entropy metallic glasses,nano-precipitate strengthened alloys,composition modulation,alloy fibers,and refractory *** the following section,the emphasis shifts to functional materials,exploring HEAs as catalysts,magneto-caloric materials,corrosion-resistant alloys,radiation-resistant alloys,hydrogen storage systems,and materials for ***,the review encompasses functional high-entropy materials outside the realm of alloys,including thermoelectric,quantum dots,nanooxide catalysts,energy storage materials,negative thermal expansion ceramics,and high-entropy wave absorption *** paper concludes with an outlook,discussing future directions and potential growth areas in the *** this comprehensive review,researchers,engineers,and scientists may gain valuable insights into the recent progress and opportunities for further exploration in the exciting domains of high-entropy alloys and functional materials.

关键词： High entropy alloys Cutting-edge structural materials Cutting-edgefunctional materials

Paired quasi-periodic pulsations of hard X-ray emission in a solar flare

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Science China(Physics,Mechanics & Astronomy) 2023年第5期66卷 195-206页

作者： Hai-Sheng zhao Dong Li Shao-Lin Xiong yan-Qiu zhang yang Su wei Chen Yi zhao xiao-Bo Li Jia-Cong Liu Wen-Xi Peng Rui Qiao Xin-Qiao Li Xiang-yang Wen Li-ming Song Shi-Jie Zheng Xin-Ying Song xiao-Yun zhao Yue Huang Shuang-Nan zhang Shuo xiao Ce Cai Zheng-Hua An Can Chen Gang Chen wei Chen yan-Qi Du Min Gao Ke Gong Dong-Ya Guo Zhi-wei Guo Jian-Jian He Bin Li Chao Li Chao-yang Li Gang Li Jian-Hui Li Lu Li qing-Xin Li yan-Guo Li Jing Liang xiao-Hua Liang Jin-Yuan Liao xiao-Jing Liu Ya-qing Liu Qi Luo Xiang Ma Bin Meng Ge Ou Dong-Li Shi Jing-yan Shi Gong-Xing Sun Xi-Lei Sun You-Li Tuo Chen-wei wang Hui wang Jin wang Jin-Zhou wang Ping wang Wen-Shuai wang Hong Wu Sheng-Lun Xie yan-Bing Xu Yu-Peng Xu wang-Chen Xue Sheng yang Min Yao Jian-Ying Ye Qi-Bin Yi Chao-Yue zhang Da-Li zhang Fan zhang Fei zhang Hong-Mei zhang Kai zhang Peng zhang xiao-Lu zhang Zhen zhang Guo-Ying zhao Shi-Yi zhao Chao Zheng Xing Zhou Yue Zhu Key Laboratory for Particle Astrophysics Institute of High Energy PhysicsChinese Academy of SciencesBeijing 100049China Purple Mountain Observatory Chinese Academy of SciencesNanjing 210023China University of Chinese Academy of Sciences Beijing 100049China Department of Astronomy Beijing Normal UniversityBeijing 100875China School of Computing and Artificial Intelligence Southwest Jiaotong UniversityChengdu 611756China Physics and Space Science College China West Normal UniversityNanchong 637002China Key Laboratory of Stellar and Interstellar Physics and Department of Physics Xiangtan UniversityXiangtan 411105China Institute of Astrophysics Central China Normal UniversityWuhan 430079China School of Physics Changchun University of Science and TechnologyChangchun 130022China College of Physics and Engineering Qufu Normal UniversityQufu 273165China College of Physics Sciences&Technology Hebei UniversityBaoding 071002China

We investigate high time resolution data obtained by the Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)during the flare event on 2022 April 21 at 01:52 *** subpeaks with durations of 4-6 s have been detected in the hard X-ray precursor phase,and the key feature is that they appear in pairs and seem like double-peak *** subpeaks are rarely observed in hard X-ray band and confirmed by the microwave obtained by Nobeyama Radio Polarimeters(NoRP)and Radio Solar Telescope Network(RSTN).While an exponential function can describe the continuum component of the time profile from the precursor to part of the impulsive *** periods of quasi-periodic pulsations(QPPs)are detected to be about 7.3 and 12.8 s for the precursor and impulsive phase,respectively,with at least 95%confidence *** paired QPPs are assumed to be double-peak QPPs and then the scenario of current loop coalescence model is found to be in good agreement with our *** precursor phase can be interpreted as the oscillating coalescence of two islands,while the impulsive phase can be interpreted as more islands to coalesce one by one to form larger islands.

关键词： solar flare QPPs loop coalescence circular-ribbon flare

In-flight Energy Calibration of the GECAM Gamma-ray Detectors

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Research in Astronomy and Astrophysics 2024年第10期24卷 48-57页

作者： Rui Qiao Dong-Ya Guo Wen-Xi Peng yan-Qiu zhang Shuo xiao Shao-Lin Xiong Chao Zheng Chao-yang Li Jia-Cong Liu wang-Chen Xue Jian-Jian He Zheng-Hua An Da-Li zhang Xin-Qiao Li Li-ming Song Shi-Jie Zheng Ke Gong Ya-qing Liu Xin-Ying Song xiao-Yun zhao Xiang-yang Wen yan-Bing Xu Xiang Ma xiao-Bo Li Ping wang Yue Huang Ce Cai Qi-Bin Yi Yi zhao Chen-wei wang Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China University of Chinese Academy of Sciences Beijing 100049China China West Normal University Nanchong 637002China Xiangtan University Xiangtan 411105China Beijing Normal University Beijing 100875China

The Gravitational wave high-energy Electromagnetic Counterpart All-sky Monitor(GECAM)mission is designed to monitor the Gamma-Ray Bursts(GRBs)associated with gravitational waves and other high-energy transient *** mission consists of two microsatellites which are planned to operate at the opposite sides of the *** GECAM satellite could detect and localize GRBs in about 8 keV-5 MeV with its 25 Gamma-Ray Detectors(GRDs).In this work,we report the in-flight energy calibration of GRDs using the characteristic gamma-ray lines in the background spectra,and show their performance evolution during the commissioning ***,a preliminary cross-calibration of energy response with Fermi GBM data is also presented,validating the energy response of GRDs.

关键词： (stars:)gamma-ray burst:general instrumentation:detectors methods:data analysis