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Image Smearing Modeling and Verification for Strapdown Star Sensor

Chinese Journal of Aeronautics 2012年第1期25卷 115-123页

作者： wang Haiyong ZHOU Wenrui CHENG xuan LIN Haoyu School of Astronautics Beihang UniversityBeijing 100191China School of Instrument Science and Opto-electronics Engineering Beihang UniversityBeijing 100191China

To further extend study on celestial attitude determination with strapdown star sensor from static into dynamic field, one prerequisite is to generate precise dynamic simulating star maps. First a neat analytical solution of the smearing trajectory caused by spacecraft attitude maneuver is deduced successfully, whose parameters cover the geometric size of optics, three-axis angular velocities and CCD integral time. Then for the first time the mathematical law and method are discovered about how to synthesize the two formulae of smearing trajectory and the static Gaussian distribution function （GDF） model, the key of which is a line integral with regard to the static GDF attenuated by a factor 1/Ls （Ls is the arc length of the smearing trajectory） along the smearing trajectory. The dynamic smearing model is then obtained, also in an analytical form. After that, three sets of typical simulating maps and data are simulated from this dynamic model manifesting the expected smearing effects, also compatible with the linear model as its special case of no boresight rotation. Finally, model validity tests on a rate turntable are carried out, which results in a mean correlation coefficient 0.920 0 between the camera images and the corresponding model simulated ones with the same parameters. The sufficient similarity verifies the validity of the dynamic smearing model. This model, after pa- rameter calibration, can serve as a front-end loop of the ground semi-physical simulation system for celestial attitude determination with strapdown star sensor.

关键词： dynamic Gaussian distribution image smearing star sensor star map simulation

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半夏泻心汤加减联合TP方案治疗晚期食管鳞癌的临床研究

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中医肿瘤学杂志 2023年第3期5卷 31-36页

作者：唐仕敏李娜王明选李勇毛英李丹丹杨帆孔德华李韵遂宁市中心医院四川遂宁629000

目的本研究通过观察半夏泻心汤加减联合紫杉醇+顺铂方案(TP方案)化疗对晚期食管鳞癌临床疗效、毒副反应、营养状况的影响,评价其有效性及安全性。方法本研究纳入遂宁市中心医院符合纳排标准的食管鳞癌患者142例,随机分为试验组和对照组... 详细信息

目的本研究通过观察半夏泻心汤加减联合紫杉醇+顺铂方案(TP方案)化疗对晚期食管鳞癌临床疗效、毒副反应、营养状况的影响,评价其有效性及安全性。方法本研究纳入遂宁市中心医院符合纳排标准的食管鳞癌患者142例,随机分为试验组和对照组,试验组71例,对照组71例。试验组使用半夏泻心汤加减联合TP方案化疗,每3周调整处方1次,连续中药治疗,对照组仅给予TP方案化疗。两组化疗均以3周为一个给药周期,最多治疗6个周期。观察两组患者近期疗效、无进展生存期(progression-free survival,PFS)、毒副反应及营养状况。结果试验组客观缓解率(objective response rate,ORR)为45.46%,对照组ORR为38.57%,两组对比,差异不具有统计学意义(χ^(2)=0.661,P=0.416)。试验组疾病控制率(disease control rate,DCR)为72.73%,对照组DCR为51.43%,两组对比,试验组优于对照组,差异具有统计学意义(χ^(2)=6.525,P=0.011)。试验组中位无进展生存期(progression-free survival,PFS)为5.9个月,对照组中位PFS为4.5个月,两组对比,试验组优于对照组,差异具有统计学意义(χ^(2)=31.597,P=0.000)。恶心呕吐程度,试验组明显优于对照组,差异具有统计学意义(P=0.001)。两组PG-SGA评分对比,试验组优于对照组,差异具有统计学意义(χ^(2)=19.799,P=0.000)。结论本研究提示半夏泻心汤加减干预提高了晚期食管鳞癌化疗的近期临床疗效、PFS,减轻了化疗毒副反应,改善了患者营养状况,具有临床应用价值。

关键词：半夏泻心汤化疗食管癌随机对照研究

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UPLC-Q-TOF/MS-Based Serum Metabolomics Reveals Potential Anti-tumor Mechanism of Banxia Xiexin Decoction in Colorectal Cancer Mice

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Chinese Journal of Integrative Medicine 2024年第7期30卷 623-632页

作者： YUE Yin-zi LI ming-xuan wang Xiao-hui QIN Yuan-yuan wang Ya-hui TAN Jin-hua SU Lian-lin YAN Shuai Department of General Surgery Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China School of Pharmacy Nanjing University of Chinese MedicineNanjing210023China Department of General Surgery Bayinguoleng Mongolian Autonomous Prefecture People’s HospitalXinjiang Uygur Autonomous RegionKorla841000China Department of Pharmacy Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China Department of Anorectal Surgery Suzhou TCM Hospital Affiliated to Nanjing University of Chinese MedicineSuzhou215009China

Objective To clarify the potential mechanism of Banxia Xiexin Decoction(BXD)on colorectal cancer(CRC)from the perspective of *** Forty male C57BL/6 mice were randomly divided into normal control(NC),azoxymethane/dextran sulfate sodium(AOM/DSS)model,low-dose BXD(L-BXD),high-dose BXD(H-BXD)and mesalamine(MS)groups according to a random number table,8 mice in each *** cancer model was induced by AOM/*** was administered daily at doses of 3.915(L-BXD)and 15.66 g/kg(H-BXD)by gavage for consecutive 21 days,and 100 mg/kg MS was used as positive *** the entire modeling cycle,colon length of mice was measured and quantity of colorectal tumors were *** spleen and thymus index were determined by calculating the spleen/thymus weight to body *** cytokine and changes of serum metabolites were analyzed by enzyme-linked immunosorbent assay kits and ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry(UPLC-Q/TOF-MS),*** Notably,BXD supplementation protected against weight loss,mitigated tumor formation,and diminished histologic damage in mice treated with AOM/DSS(P<0.05 or P<0.01).Moreover,BXD suppressed expression of serum inflammatory enzymes,and improved the spleen and thymus index(P<0.05).Compared with the normal group,102 kinds of differential metabolites were screened in the AOM/DSS group,including 48 potential biomarkers,involving 18 main metabolic *** 18 potential biomarkers related to CRC were identified,and the anti-CRC mechanism of BXD was closely related to D-glutamine and D-glutamate metabolism,phenylalanine,tyrosine and tryptophan biosynthesis,arginine biosynthesis,nitrogen metabolism and so *** BXD exerts partial protective effects on AOM/DSS-induced CRC by reducing inflammation,protecting organism immunity ability,and regulating amino acid metabolism.

关键词： colorectal cancer metabolomics ultra performance liquid chromatography-quadrupole/time-of-flight mass spectrometry azoxymethane dextran sulfate sodium Banxia Xiexin Decoction Chinese medicine

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A multi-objective optimization based on machine learning for dimension precision of wax pattern in turbine blade manufacturing

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Advances in Manufacturing 2024年第3期12卷 428-446页

作者： Jing Dai Song-Zhe Xu Chao-Yue Chen Tao Hu San-San Shuai Wei-Dong xuan Jiang wang Zhong-ming Ren State Key Laboratory of Advanced Special Steels School of Materials Science and EngineeringShanghai UniversityShanghai200444People’s Republic of China

Wax pattern fabrication in the investment casting of hollow turbine blades directly determines the dimension accuracy of subsequent casting,and therefore significantly affects the quality of final *** this work,we develop a machine learning-based multi-objective optimization framework for improving dimension accuracy of wax pattern by optimizing its process *** consider two optimization objectives on the dimension of wax pattern,i.e.,the surface warpage and core *** active learning of Bayesian optimization is employed in data sampling to determine process parameters,and a validated numerical model of injection molding is used to compute objective results of dimension under varied process *** collected dataset is then leveraged to train different machine learning models,and it turns out that the Gaussian process regression model performs best in prediction accuracy,which is then used as the surrogate model in the optimization framework.A genetic algorithm is employed to produce a non-dominated Pareto front using the surrogate model in searching,followed by an entropy weight method to select the most optimal solution from the Pareto *** optimized set of process parameters is then compared to empirical parameters obtained from previous trial-and-error experiments,and it turns out that the maximum and average warpage results of the optimized solution decrease 26.0%and 20.2%,and the maximum and average errors of wall thickness compared to standard part decrease from 0.22 mm and 0.0517 mm using empirical parameters to 0.10 mm and 0.0356 mm using optimized parameters,*** framework is demonstrated capable of addressing the challenge of dimension control arising in the wax pattern production,and it can be reliably deployed in varied types of turbine blades to significantly reduce the manufacturing cost of turbine blades.

关键词： Hollow turbine blade Wax pattern fabrication Dimension control Multi-objective optimization Machine learning Numerical simulation

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Solvent-mediated handedness inversed and amplified circularly polarized luminescence system based on camptothecin derivative

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Chinese Chemical Letters 2023年第2期34卷 188-192页

作者： xuan Wu ming Liu Cheng Zheng Yingying wang Yujing Zheng Yuna Qian Zhiyong Liao Guoyong Fang Jianliang Shen Wenzhou Institute University of Chinese Academy of SciencesWenzhou 325000China School of Ophthalmology and Optometry School of Biomedical EngineeringWenzhou Medical UniversityWenzhou 325035China Oujiang Laboratory(Zhejiang Lab for Regenerative Medicine Vision and Brain Health)Wenzhou 325001China College of Life and Environmental Science Wenzhou UniversityWenzhou 325000China College of Chemistry and Materials Engineering Wenzhou UniversityWenzhou 325000China National Laboratory of Solid State Microstructures Nanjing UniversityNanjing 210093China

To realize the handedness controllable circularly polarized luminescence(CPL) system remains challenging. Herein, the solvent-mediated CPL inversion and amplification systems were successfully constructed by camptothecin derivative(CPT-A). Due to the planar structure of N,N-dimethylformamide, it could coassemble with CPT-A, resulting in the alteration of g_(lum) from –0.0082 to +0.0085 by increasing water content. While in the non-planar solvent(hexafluoroisopropanol), the g_(lum) was amplified to 0.034 with the increase in water content. Moreover, the CPT-A could react with the glutathione, resulting in the anticancer drug CPT to make it more toxic to the cancer cells. Overall, the handedness controllable CPL systems were realized by tuning the supramolecular self-assembly of a prodrug.

关键词： Circularly polarized luminescence Chirality inversion and amplification Solvent-incorporated self-assembly Camptothecin derivative Stimuli-responsiveness

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Long-term outcome of indwelling colon observed seven years after radical resection for rectosigmoid cancer: A case report

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World Journal of Clinical Cases 2021年第19期9卷 5252-5258页

作者： Zi-xuan Zhuang ming-Tian Wei Xu-Yang Yang Yang Zhang Wen Zhuang Zi-Qiang wang Department of Gastrointestinal Surgery West China HospitalSichuan UniversityChengdu 610041Sichuan ProvinceChina

BACKGROUND Indwelling colon is characterized by an excluded segment of the colon after surgical diversion of the fecal stream with colostomy so that contents are unable to pass through this part of the *** report a rare case of purulent colonic necrosis that occurred 7 years after surgical colonic *** SUMMARY A 73-year-old male had undergone extended radical resection for rectosigmoid *** invaded ileocecal area and sigmoid colon were removed during the procedure,and the ileum was anastomosed side-to-side with the *** excluded ascending,transverse,and descending colon were sealed at both ends and left in the *** 7 years,the patient developed persistent abdominal pain and ***-up indicated intestinal *** patient underwent ultrasound-guided catheter drainage of the descending colon and a large amount of viscous liquid was drained,but the symptoms persisted;therefore,surgery was ***,extensive adhesions were found in the abdominal cavity,and the small intestine and the indwelling colon were widely *** dilated colon was 56 cm long,5 cm wide(diameter),and contained about 1500 mL of viscous *** indwelling colon was surgically removed and its histopathological examination revealed colonic congestion and necrosis with hyperplasia of granulation *** bacterial culture of the secretions was *** patient recovered after the *** Although colonic exclusion is routinely performed,this report aimed to increase awareness regarding the possible long-term complications of indwelling colon.

关键词： Colon Colectomy Intestinal obstruction Diversion colitis Sigmoid cancer Colitis Case report

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Exploring Image Generation for UAV Change Detection

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IEEE/CAA Journal of Automatica Sinica 2022年第6期9卷 1061-1072页

作者： xuan Li Haibin Duan Yonglin Tian Fei-Yue wang Peng Cheng Laboratory Shenzhen 518000China IEEE State Key Laboratory of Virtual Reality Technology and Systems School of Automation Science and Electrical EngineeringBeihang UniversityBeijing 100083 Department of Automation University of Science and Technology of ChinaHefei 230027 State Key Laboratory for Management and Control of Complex Systems Institute of AutomationChinese Academy of SciencesBeijing 100190China Research Center for Computational Experiments and Parallel Systems Technology National University of Defense TechnologyChangsha 410073China

Change detection(CD)is becoming indispensable for unmanned aerial vehicles(UAVs),especially in the domain of water landing,rescue and ***,even the most advanced models require large amounts of data for model training and ***,sufficient labeled images with different imaging conditions are *** by computer graphics,we present a cloning method to simulate inland-water scene and collect an auto-labeled simulated *** simulated dataset consists of six challenges to test the effects of dynamic background,weather,and noise on change detection ***,we propose an image translation framework that translates simulated images to synthetic *** framework uses shared parameters(encoder and generator)and 22×22 receptive fields(discriminator)to generate realistic synthetic images as model training *** experimental results indicate that:1)different imaging challenges affect the performance of change detection models;2)compared with simulated images,synthetic images can effectively improve the accuracy of supervised models.

关键词： Change detection computer graphics image translation simulated images synthetic images unmanned aerial vehicles(UAVs)

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香石竹植物伤流液及其中有机成分的提取研究

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云南师范大学学报（自然科学版） 2011年第3期31卷 68-70页

作者：王明轩范利花段良飞李池丽段军雄官会林高旭红云南师范大学能源与环境科学学院可再生能源材料先进技术与制备教育部重点实验室云南昆明650092

在总结了已报道的植物伤流液提取方法的基础上,对香石竹植物伤流液及其中有机成分的提取方法进行了研究,研究结果表明选用加压收集法来提取香石竹植物伤流液,能够获得较好的提取效果。此外,实验结果还表明香石竹健康植株和病害植株伤流... 详细信息

在总结了已报道的植物伤流液提取方法的基础上,对香石竹植物伤流液及其中有机成分的提取方法进行了研究,研究结果表明选用加压收集法来提取香石竹植物伤流液,能够获得较好的提取效果。此外,实验结果还表明香石竹健康植株和病害植株伤流液的提取物在颜色、状态及溶解性等方面存在明显差异。

关键词：香石竹伤流液提取研究

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Intercultural Understanding in A Global Context

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学术界 2016年第12期 298-302页

作者： wang xuan Shanghai International Studies University North China University of Water Resources and Electric Power

Intercultural understanding has become more important in a globalized world with increasing intercultural contact and cultural *** reviewing the main studies about intercultural understanding at home and abroad,a survey was conducted by the means of qualitative methods such as interview and focus group,together with questionnaires to help us have a closer look at the practice of intercultural understanding in Shanghai some problems are discussed and suggestions for future research are proposed.

关键词： Intercultural understanding global context field research

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What Does ChatGPT Say:The DAO from Algorithmic Intelligence to Linguistic Intelligence

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IEEE/CAA Journal of Automatica Sinica 2023年第3期10卷 575-579页

作者： Fei-Yue wang Qinghai Miao xuan Li Xingxia wang Yilun Lin School of Artificial Intelligence University of Chinese Academy of SciencesBeijing 100049China State Key Laboratory for Management and Control of Complex Systems Chinese Academy of SciencesBeijing 100190China Virtual Reality Fundamental Research Laboratory Department of Mathematics and TheoriesPeng Cheng LaboratoryShenzhen 518000China Urban Computing Lab Department of Applied ResearchShanghai AI LaboratoryShanghai 200232China IEEE

THE well-known ancient Chinese philosopher Lao Tzu(老子)or Laozi(6th~4th century BC during the Spring and Autumn period)started his classic Tao Teh Ching《道德经》or Dao De Jing(see Fig.1)with six Chinese characters:"道(Dao)可(Ke)道(Dao)非(Fei)常(Chang)道(Dao)",which has been traditionally interpreted as“道可道,非常道”or"The Dao that can be spoken is not the eternal Dao".

关键词： DAO Intelligence Spring

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