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女英雄的想像與歷史記憶

岭南学报 2015年第1期 85-108页

作者：李惠儀哈佛大學

明季女英雄是一個具彈性的象徵符號,代表異彩紛呈的議論、抒情和想像空間。歷史與文學如何交錯?滄桑巨變的經歷與記憶,為何藉女英雄想像為媒介?不同的歷史環境如何塑造歷史記憶?明季女英雄的壓抑與重構,如何應運而生?清末民初與抗戰期... 详细信息

明季女英雄是一個具彈性的象徵符號,代表異彩紛呈的議論、抒情和想像空間。歷史與文學如何交錯?滄桑巨變的經歷與記憶,為何藉女英雄想像為媒介?不同的歷史環境如何塑造歷史記憶?明季女英雄的壓抑與重構,如何應運而生?清末民初與抗戰期間述説明末女英雄,激勵人心,救亡圖存的目標極明顯。相對而言,明末清初的同題書寫複雜而多元。其中有記實的層面,即不願獨立特行的奇女子湮没無聞,亦有馳騁想像,純屬虚構的故事。然而無論虚實,均呈現晚明以來對此話題之特殊興趣。廣義而言,這主題也許可溯源於'好奇'的文學傳統,其中包涵追求解脱、投射理想、抒發憤懣,種種創作動機。間或緊扣時代,成為歷史判斷的關鍵,歷史記憶的依附。同時,世變與女詩人的英雄想像息息相關。明清之際女性文學主流之一是憂國傷時的詩詞。從戎靖亂的記憶或幻想,間或引發對性別定位的質疑,間或醖釀詩心之覺醒。書寫19世紀離亂的女詩人,乃至晚清秋瑾,均屬於此一隱約的系譜。

关键词：女英雄想像歷史記憶明清之際明季

Effects of root morphology and anatomy on cadmium uptake and translocation in rice(Oryza sativa L.)

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Journal of Environmental Sciences 2019年第1期31卷 296-306页

作者： Lu Huang wai Chin li Nora Fung yee Tam Zhihong Ye School of life Sciences Sun Yat-sen University Department of Science and Environmental Studies The Education University of Hong Kong State Key Laboratory in Marine Pollution and Department of Chemistry City University of Hong Kong

A clear description of the certain mechanisms of cadmium(Cd) uptake and translocation in rice(Oryza sativa L.) may help to reduce Cd accumulation in rice grain. Hydroponic experiments were carried out to determine the effects of cultivation conditions(aerated and stagnant) on the uptake, translocation and subcellular distribution of Cd in relation to the morphology and anatomy of roots in two rice genotypes with different Cd accumulations in grains. Marked differences in morphology and anatomy were observed between these two genotypes under different cultivation conditions. Genotypes with low Cd accumulation in grains tended to develop fewer root tips per root surface area, larger root porosity and more mature apoplastic barriers. The stagnant cultivation condition decreased the number of root tips per root surface area but increased root porosity and accelerated apoplastic barrier formation in root *** Cd uptake studies revealed that rice plants with fewer number of root tips per root surface area reduced root Cd uptake ability, while mature apoplastic barriers increased root Cd retention in cell walls and the symplast. Thus, the fewer number of root tips per root surface area and the earlier formation of mature apoplastic barriers led to lower Cd uptake and translocation. The results indicated that the morphology and anatomy of roots could play important roles in Cd uptake and translocation in rice, and could be influenced by both genotype and cultivation conditions. The present results would be useful in screening and planting rice plants with low Cd accumulation.

关键词： Apoplastic barriers Cadmium Rice Root morphology

hale gas reservoir modeling and production evaluation considering complex gas transport mechanisms and dispersed distribution of kerogen

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Petroleum Science 2021年第1期18卷 195-218页

作者： Jie Zeng Jishan liu wai li yee-Kwong Leong Derek Elsworth Jianchun Guo School of Engineering The University of Western Australia35 Stirling HighwayPerthWA 6009Australia Department of Energy and Mineral Engineering G3 Center and Energy InstituteThe Pennsylvania State UniversityUniversity ParkPA 16802USA State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation Southwest Petroleum UniversityChengdu 610500China

Stimulated shale reservoirs consist of kerogen,inorganic matter,secondary and hydraulic *** dispersed distribution of kerogen within matrices and complex gas flow mechanisms make production evaluation *** we establish an analytical method that addresses kerogen-inorganic matter gas transfer,dispersed kerogen distribution,and complex gas flow mechanisms to facilitate evaluating gas *** matrix element is defined as a kerogen core with an exterior inorganic *** most previous models,we merely use boundary conditions to describe kerogen-inorganic matter gas transfer without the instantaneous kerogen gas source *** is closer to real inter-porosity flow conditions between kerogen and inorganic *** diffusion,surface diffusion,adsorption/desorption,and slip corrected flow are involved in matrix gas ***-fracture coupling is realized by using a seven-region linear flow *** model is verified against a published model and field *** reveal that inorganic matrices serve as a major gas source especially at early *** provides limited contributions to production even under a pseudo-steady *** properties’influence starts from the late matrix-fracture inter-porosity flow regime,while inorganic matter properties control almost all flow regimes except the early-mid time fracture linear flow *** contribution of different linear flow regions is also documented.

关键词： Analytical solution Shale gas reservoir Well performance Kerogen and inorganic matter

唇部血管瘤早期手术治疗指南：214例临床经验总结

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中国美容整形外科杂志 2012年第3期23卷 I0017-I0017页

作者： wai-yee li Obaid Chaudhry John F. Reinisch 魏峰高景恒张晨美国加利福尼亚州洛杉矶南加州大学凯克医学院整形再造外科中心爱尔兰都柏林爱尔兰皇家外科医学院加利福尼亚州比佛利山西达斯西奈医学中心《中国美容整形外科杂志》编辑部大连大学附属新华医院整形外科

背景与目的血管瘤是最常见的婴幼儿血管病变。因为血管瘤大多位于面部，所以患儿家长恐其损毁面容而明显感到焦虑。因为婴幼儿血管瘤会在一段时间后明显改善，所以通常对其行“观察等待”的保守处理方式。但是，唇部血管瘤较明显，即便... 详细信息

背景与目的血管瘤是最常见的婴幼儿血管病变。因为血管瘤大多位于面部，所以患儿家长恐其损毁面容而明显感到焦虑。因为婴幼儿血管瘤会在一段时间后明显改善，所以通常对其行“观察等待”的保守处理方式。但是，唇部血管瘤较明显，即便消退后也会遗留残余畸形，所以保守观察的方式并不适应。方法1992．2006年洛杉矶儿童医院收治的行手术切除的上、下唇部婴幼儿血管瘤患儿，对相关信息列图表进行回顾性分析。结果本组214例唇部血管瘤患儿，手术时平均年龄23．6个月。

关键词：唇部血管瘤早期手术临床经验治疗指南婴幼儿血管瘤患儿家长血管病变手术切除

Polyvinylpyrrolidone-based bioink:influence of bioink properties on printing performance and cell proliferation during inkjet-based bioprinting

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Bio-Design and Manufacturing 2023年第6期6卷 676-690页

作者： Wei Long Ng Xi Huang Viktor Shkolnikov Ratima Suntornnond wai yee Yeong HP-NTU Digital Manufacturing Corporate Lab Nanyang Technological University(NTU)Singapore 637460Singapore Singapore Centre for 3D Printing(SC3DP) School of Mechanical and Aerospace EngineeringNanyang Technological University(NTU)Singapore 639798Singapore HP Inc. Palo AltoCA 94304USA

Among the different bioprinting techniques,the drop-on-demand(DOD)jetting-based bioprinting approach facilitates contactless deposition of pico/nanoliter droplets ofmaterials and cells for optimal cell–matrix and cell–cell *** bioinks play a critical role in the bioprinting process,there is a poor understanding of the influence of bioink properties on printing performance(such as filament elongation,formation of satellite droplets,and droplet splashing)and cell health(cell viability and proliferation)during the DOD jetting-based bioprinting *** inert polyvinylpyrrolidone(PVP360,molecular weight=360 kDa)polymerwas used in this study to manipulate the physical properties of the bioinks and investigate the influence of bioink properties on printing performance and cell *** experimental results showed that a higher bioink viscoelasticity helps to stabilize droplet filaments before rupturing from the nozzle *** highly stretched droplet filament resulted in the formation of highly aligned“satellite droplets,”which minimized the displacement of the satellite droplets away from the predefined ***,a significant increase in the bioink viscosity facilitated droplet deposition on the wetted substrate surface in the absence of splashing and significantly improved the accuracy of the deposited main *** analysis showed that cell-laden bioinks with higher viscosity exhibited higher measured average cell viability(%),as the presence of polymer within the printed droplets provides an additional cushioning effect(higher energy dissipation)for the encapsulated cells during droplet impact on the substrate surface,improves the measured average cell viability even at higher droplet impact velocity and retains the proliferation capability of the printed *** the influence of bioink properties(e.g.,bioink viscoelasticity and viscosity)on printing performance and cell proliferation is important for the formulation

关键词： Biofabrication 3D bioprinting Drop-on-demand bioprinting Bioink properties Polyvinylpyrrolidone

Exploratory use of ultrasound to determine whether demyelination following carpal tunnel syndrome co-exists with axonal degeneration

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Neural Regeneration Research 2018年第2期13卷 317-323页

作者： Xue Deng Lai-Heung Phoebe Chau Suk-yee Chiu Kwok-Pui Leung Sheung-wai li Wing-Yuk Ip Department of Orthopedics & Traumatology The University of Hong Kong Clinical Electro-diagnostic Unit Tung Wah Hospital Department of Medicine The University of Hong Kong

Carpal tunnel syndrome （CTS） accompanied by secondary axonal degeneration cannot be clearly dis- criminated using the current cross-validated ultrasound severity classification system. This study aimed at exploring cut-off values of ultrasound parameters, including wrist cross-sectional area （W-CSA）, wrist perimeter （W-P）, ratio of cross-sectional area （R-CSA） and perimeter （R-P）, changes of CSA and P from wrist to one third distal forearm （△CSA＆AP） for differentiation. Seventy-three patients （13 male and 60 female） were assigned into group A （demyelination only, n = 40） and group B （demyelination with secondary axonal degeneration, n = 33） based on the outcomes of nerve conduction studies （NCS）. Receiver Operative Characteristics （ROC） curves were plotted to obtain sensitivity, specificity, and accuracy of cut- off values for all the ultrasound parameters. The overall identified cut-off values （W-CSA 12.0 mm2, W-P 16.27 mm, R-CSA 1.85, R-P 1.48, △CSA 6.98 mm2, △P 5.77 mm） had good sensitivity （77.1-88.6%）, fair specificity （40-62.2%） and fair-to-good accuracy （0.676-0.758）. There were also significant differences in demographics （age and severity gradation, P 〈 0.001）, NCS findings （wrist motor latency and conduction velocity, P 〈 0.0001; wrist motor amplitude, P 〈 0.05; distal sensory latency, P 〈 0.05; sensory amplitude, P 〈 0.001） and ultrasound measurements （W-CSA, W-P, R-CSA, R-P, △CSA＆△P, P 〈 0.05） between groups. These findings suggest that ultrasound can be potentially used to differentiate demyelinating CTS with sec- ondary axonal degeneration and provide better treatment guidance.

关键词： carpal tunnel syndrome nerve conduction studies ultrasound receiver operating characteristic curve peripheral nerve compression injury ultrasonography neural conduction axonal degeneration neural regeneration

Engineering behaviour of in situ cored deep cement mixed marine deposits subjected to undrained and drained shearing

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第5期16卷 1749-1760页

作者： Wei li Chung yee Kwok Faculty of Engineering China University of GeosciencesWuhan430074China Department of Civil Engineering The University of Hong Kong999000Hong Kong SARChina

The deep cement mixing(DCM)is used to improve the capacity and reduce the settlement of the soft ground by forming cemented clay *** investigation on the mechanical behaviour of the DCM samples is limited to either laboratory-prepared samples or in-situ samples under unconfined *** this study,a series of drained and undrained triaxial shearing tests was performed on the in-situ cored DCM samples with high cement content to assess their mechanical *** is found that the drainage condition affects significantly the stiffness,peak and residual strengths of the DCM samples,which is mainly due to the state of excess pore water pressure at different strain levels,*** positive before the peak deviatoric stress and negative after the peak deviatoric stress,in the undrained *** slope of the failure envelope changes obviously with the confining pressures,being steeper at lower stress levels and flatter at higher stress *** strength parameters,effective cohesion and friction angle obtained from lower stress levels(c′0 andφ′0)are 400 kPa and 58°,respectively,which are deemed to be true for design in most DCM applications where the in-situ stress levels are normally at lower values of 50-200 ***,the computed tomography(CT)scanning system was adopted to visualize the internal structures of DCM *** is found that the clay pockets existing inside the DCM samples due to uneven mixing affect markedly their stress-strain behaviour,which is one of the main reasons for the high variability of the DCM samples.

关键词： Deep cement mixing(DCM) In-situ cored sample Triaxial shearing Drainage condition Confining pressure Computed tomography(CT)

A facile method to fabricate cell-laden hydrogel microparticles of tunable sizes using thermal inkjet bioprinting

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Droplet 2024年第4期3卷 29-38页

作者： Ratima Suntornnond Wei Long Ng Viktor Shkolnikov wai yee Yeong HP-NTU Digital Manufacturing Corporate Lab Nanyang Technological University(NTU)Singapore Singapore Centre for 3D Printing(SC3DP) School of Mechanical and Aerospace EngineeringNanyang Technological University(NTU)Singapore HP Inc. Palo AltoCaliforniaUSA

This study investigates the application of a drop-on-demand(DOD)thermal inkjet(TIJ)-based bioprinting system for the fabrication of cell-laden hydrogel microparticles(HMPs)with tunable *** TIJ bioprinting technique involves the formation of vapor bubbles within the print chamber through thermal energy,expelling small droplets of bio-ink onto a *** study employs a heat-treated saponified gelatin-based bio-ink,*** bio-ink is modified through methacrylic anhydride functionalization and undergoes subsequent saponification and heat treatment *** concentrations of SPAN 80 surfactant in mineral oil were evaluated to assess their influence on HMP size and *** results indicate a direct correlation,with higher SPAN 80 concentrations resulting in smaller and more stable *** study further investigates the influence of jetting volume on HMP size distribution,revealing that larger jetting volumes lead to increased HMP sizes,attributed to droplet *** is supported by our further study via a Monte Carlo simulation,which shows that the mean droplet diameter grows approximately linear with the number of dispensed *** addition,the study demonstrates the capability of the TIJ bioprinting system to achieve multimaterial encapsulation within HMPs,exemplified by staining living cells with distinct cytoplasmic membrane *** presented approach provides insights into the controlled fabrication of cell-laden HMPs,highlighting the versatility of the TIJ bioprinting system for potential applications in tissue engineering and drug delivery.

关键词： printing thermal sizes

Outlook of PINK1/Parkin signaling in molecular etiology of Parkinson's disease,with insights into Pink1 knockout models

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Zoological Research 2023年第3期44卷 559-576页

作者： Zhangting Wang See-Wing Chan Hui Zhao Kai-Kei Miu wai-yee Chan School of Biomedical Sciences Faculty of MedicineThe Chinese University of Hong KongHong Kong SARChina Kunming Institute of Zoology-The Chinese University of Hong Kong(KIZ-CUHK)Joint Laboratory of Bioresources and Molecular Research of Common Diseases Hong Kong SARChina Hong Kong Branch of CAS Center for Excellence in Animal Evolution and Genetics School of Biomedical SciencesThe Chinese University of Hong KongHong Kong SARChina Key Laboratory for Regenerative Medicine Ministry of EducationSchool of Biomedical SciencesThe Chinese University of Hong KongHong Kong SARChina

Parkinson’s disease(PD)relates to defective mitochondrial quality control in the dopaminergic motor *** studies have revealed that PINK1 and Parkin mutations are indicative of a heightened propensity to PD onset,pinpointing mitophagy and inflammation as the culprit pathways involved in neuronal loss in the substantia nigra(SNpc).In a reciprocal manner,LRRK2 functions in the regulation of basal flux and inflammatory responses responsible for PINK1/Parkin-dependent mitophagy *** intervention in these diseasemodifying pathways may facilitate the development of novel PD therapeutics,despite the current lack of an established drug evaluation *** such,we reviewed the feasibility of employing the versatile global Pink1knockout(KO)rat model as a self-sufficient,spontaneous PD model for investigating both disease etiology and drug *** rats retain clinical features encompassing basal mitophagic flux changes with PD *** demonstrate the versatility of this PD rat model based on the incorporation of additional experimental insults to recapitulate the proinflammatory responses observed in PD patients.

关键词： Parkinson’s disease Mitophagy Inflammatory response Genetic model Pink1 KO rats