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对于非选择性急性腹痛病人腹部CT检查中观察者间的一致性

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国际医学放射学杂志 2009年第4期32卷 411-411页

作者： A.van Randen w.laméris C.Y.Nio A.M.Spijkerboer M.A.Meier C.Tutein Nolthenius 华锐 Academic Medical Center

对急症科非选择性急性腹痛病人的腹部CT进行观察者间一致性评估。前瞻性研究连续200例急性腹痛病人,对所有病人仅行静脉注射对比剂后的多层螺旋CT检查。由3名放射科医师独立阅片,记录特征性影像学表现和病历记录的最终诊断。对于所有的... 详细信息

对急症科非选择性急性腹痛病人的腹部CT进行观察者间一致性评估。前瞻性研究连续200例急性腹痛病人,对所有病人仅行静脉注射对比剂后的多层螺旋CT检查。由3名放射科医师独立阅片,记录特征性影像学表现和病历记录的最终诊断。对于所有的常见急腹症诊断．我们计算一致性的比例和K值。本组被评估病人的平均年龄为46岁（范嗣19～94岁）,其中54％为女性。总体诊断一致性较高,中位数κ值为0．66。而对于一些特殊的急腹症诊断一致性更高,

关键词：观察者间腹部CT 急性腹痛

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阑尾炎高度可能性的超声和CT影像特征概况

国际医学放射学杂志 2010年第5期 497-497页

作者： A.van Randen w.laméris H.w.van Es w.ten Hove w.H.Bouma M.S.van Leeuwen 李艳辉 Department of Radiology Academic Medical CenterUniversity of Amsterdam

关键词：急性阑尾炎 CT 超声检查影像学特征急腹症

超声与CT在急腹症常见病因诊断准确性方面的比较

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国际医学放射学杂志 2011年第5期 500-500页

作者： A.van Randen w.laméris H.w.van Es H.P.M.van Heesewijk B.van Ramshorst w.ten Hove 王翠 Department of Radiology (suite G1-227) Academic Medical CentreMeibergdreef 91105 AZ AmsterdamThe Netherlands

目的对照研究超声与CT在急腹症的常见病因诊断方面的准确性。材料与方法本研究对象的入组条件是腹痛时间超过2h且少于5d的连续性急诊病人,所有病人均

关键词：急腹症 CT 超声急诊科

临床疑似急性阑尾炎病人行条件性CT检查与即刻增强CT检查的成像策略对比

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国际医学放射学杂志 2015年第5期 508-508页

作者： J.J.Atema S.L.Gans A.Van Randen w.laméris H.w.van Es J.P.M.van Heesewijk 马菊香 Department of Surgery(G4-142) Academic Medical Centre

摘要目的对比研究临床疑似阑尾炎病人行条件性CT检查(当超声检查阴性或诊断不明时)和直接CT检查两者阑尾炎的诊断准确率。方法本研究为前瞻性诊断准确性研究,收集急性腹痛成人病例。所有病人行超声和CT检查。阅片者在不知另外一种成像... 详细信息

摘要目的对比研究临床疑似阑尾炎病人行条件性CT检查(当超声检查阴性或诊断不明时)和直接CT检查两者阑尾炎的诊断准确率。方法本研究为前瞻性诊断准确性研究,收集急性腹痛成人病例。所有病人行超声和CT检查。阅片者在不知另外一种成像结果情况下分别阅片。仅临床疑似阑尾炎病人纳入本研究。随访6个月后,由专家组参考临床标准

关键词：阑尾炎病人条件性检查诊断 CT

Experimental Investigation of the Decay from A Ship’s Propeller

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China Ocean Engineering 2011年第2期25卷 265-284页

作者： w.lam G.A.Hamill 宋永臣 D.J.Robinson S.Raghunathan Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education Dalian University of Technology Queen's University Belfast

In the present study, an experimental investigation of the decay of the maximum velocity and its turbulent characteristics behind a ship propeller, in ＂bollard pull＂ condition （zero speed of advance）, is reported. Velocity measurements were performed in laboratory by use of a Laser Doppler Anemometry （LDA） measurement system. Earlier researchers described that the maximum axial velocity is constant at the initial stage of a ship＇s propeller jet （Fuehrer and Romisch, 1977; Blaauw and van de Kaa, 1978; Berger et al, 1981; Verhey, 1983） as reported in a pure water jet （Albertson et al., 1950; Lee et al., 2002; Dai, 2005）, but a number of researchers disagreed with the constant velocity assumption. The present study found that the maximum axial velocity decays in the zone of flow establishment and the zone of established flow with different rates. The investigation provides an insight into the decays of both the maximum velocity and the maximum turbulent fluctuation in axial, tangential and radial components and the decay of the maximum turbulent kinetic energy. Empirical equations are proposed to allow coastal engineers to estimate the jet characteristics from a ship＇s propeller.

关键词： ship's propeller jet Laser Doppler Anemometry (LDA) maximum velocity decay

TRMT6 and TRMT61A facilitated acute pancreatitis severity via regulation of neutrophil function

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Science China Life Sciences 2025年

作者： Yuan Dong Li Su Sin Man lam Cen Yan Yalan Deng Guotao Lu Jinkui Yang Guanghou Shui Yingmei Feng Beijing Institute of Hepatology Beijing Youan HospitalCapital Medical University Department of Science and Development Beijing Youan HospitalCapital Medical University Laboratory for Clinical Medicine Capital Medical University Neuroscience Research Institute Peking University Center of Medical and Health AnalysisPeking University State Key Laboratory of Molecular Developmental Biology Institute of Genetics and Developmental BiologyChinese Academy of Sciences Pancreatic Center Department of GastroenterologyAffiliated Hospital of Yangzhou UniversityYangzhou University Beijing Key Laboratory of Diabetes Research and Care Department of EndocrinologyBeijing Tongren HospitalCapital Medical University

Dear Editor,Type 2 diabetes mellitus (T2DM) has been identified as a risk factor for increased severity in acute pancreatitis (AP)(Mikóet al,2018).However,to date,no studies have simultaneously included healthy individuals,T2DM patients,and AP patients to investigate which diabetes-associated metabolites are linked to AP severity.

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A novel method for clustering cellular data to improve classification

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Neural Regeneration Research 2025年第9期20卷 2697-2705页

作者： Diek w.wheeler Giorgio A.Ascoli Center for Neural Informatics Structures&PlasticityKrasnow Institute for Advanced Study Bioengineering Department Volgenau School of Engineering George Mason University FairfaxVAUSA

Many fields,such as neuroscience,are experiencing the vast prolife ration of cellular data,underscoring the need fo r organizing and interpreting large datasets.A popular approach partitions data into manageable subsets via hierarchical clustering,but objective methods to determine the appropriate classification granularity are *** recently introduced a technique to systematically identify when to stop subdividing clusters based on the fundamental principle that cells must differ more between than within *** we present the corresponding protocol to classify cellular datasets by combining datadriven unsupervised hierarchical clustering with statistical *** general-purpose functions are applicable to any cellular dataset that can be organized as two-dimensional matrices of numerical values,including molecula r,physiological,and anatomical *** demonstrate the protocol using cellular data from the Janelia MouseLight project to chara cterize morphological aspects of neurons.

关键词： cellular data clustering dendrogram data classification Levene's one-tailed statistical test unsupervised hierarchical clustering

Genistein:a possible solution for the treatment of Alzheimer’s disease

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Neural Regeneration Research 2025年第10期20卷 2903-2905页

作者： Karolina Pierzynowska Bartosz Karaszewski Grzegorz węgrzyn Department of Molecular Biology University of GdanskGdanskPoland Gdansk Polandand Department of Adult NeurologyFaculty of MedicineMedical University of GdanskGdanskPoland

Neurodegenerative diseases are defined as disorders resulting from the slow and progressive loss of function and eventual death of neural cells that result from the primary pathology of nervous *** can lead to severe nervous system dysfunction,eventually affecting multiple organs and *** hundred neurodegenerative diseases have been described,and owing to their prevalence,severity.

关键词： organs Alzheimer death

Glia-to-neuron reprogramming to the rescue?

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Neural Regeneration Research 2025年第5期20卷 1395-1396页

作者： Jack w.Hickmott Cindi M.Morshead Department of Surgery University of TorontoTorontoONCanada Donnelly Centre for Cellular and Biomolecular Research TorontoONCanada Institute of Biomedical Engineering University of TorontoTorontoONCanada The KITE Research Institute Toronto Rehabilitation InstituteUniversity Health NetworkTorontoONCanada

Over the last two decades,the dogma that cell fate is immutable has been increasingly challenged,with important implications for regenerative *** brea kth rough discovery that induced pluripotent stem cells could be generated from adult mouse fibroblasts is powerful proof that cell fate can be *** exciting extension of the discovery of cell fate impermanence is the direct cellular reprogram ming hypothesis-that terminally differentiated cells can be reprogrammed into other adult cell fates without first passing through a stem cell state.

关键词： programming passing proof