检索结果-南通市图书馆

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

新地缘政治时代下的跨大西洋关系

国际政治 2006年第1期

作者：卡斯滕d·福格特（Karsten d.voigt）

柏林墙的倒塌和“9·11”恐怖袭击事件使全球地缘政治环境发生了重大变化，也改变了德美和欧美关系。本文认为：面对这一变化，如果仍固守冷战时期形成的行为方式和理念，已不利于德、欧、美跨大西洋关系的发展。德国、欧洲和美国应通... 详细信息

柏林墙的倒塌和“9·11”恐怖袭击事件使全球地缘政治环境发生了重大变化，也改变了德美和欧美关系。本文认为：面对这一变化，如果仍固守冷战时期形成的行为方式和理念，已不利于德、欧、美跨大西洋关系的发展。德国、欧洲和美国应通过跨大西洋政策和跨大西洋机构的改革，构建一种新的跨大西洋关系。

关键词：新地缘政治跨大西洋关系德美关系欧美关系

来源：人大复印报刊资料评论

在线全文

人大复印报刊资料

学校读者我要写书评

暂无评论

重度多形性红斑对α干扰素治疗应答

世界核心医学期刊文摘（皮肤病学分册） 2006年第4期2卷 11-11页

作者： Geraminejad P. Walling H.W. voigt M.d. Stone M.S. 李政霄 University of Iowa Department of Dermatology Boyd Tower 200 Hawkins Dr Iowa City IA 52242 United States Dr.

Erythema multiforme (EM) is a targetoid eruption with interface pathology often triggered by a hypersensitivity response to a variety of infections, most commonly herpes simplex virus. Hepatitis C virus is rarely associated with EM. We present a 37-year-old man with an 8-year history of severe EM unresponsive to valacyclovir, acitretin, and cyclosporin, and marginally responsive to high- dose prednisone. The eruption had cleared 6 years previously during treatment with interferon for his concurrent hepatitis C virus. Although his viral titer was undetectable, we initiated therapy with interferon and ribavirin. The patient responded dramatically within 2 months and remained clear of EMafter 1 year of continued interferon therapy. This is the third case reported in the world literature documenting a response of EM to interferon, and the first case in which hepatitis C virus was undetectable in serum prior to interferon therapy.

关键词：多形性红斑治疗应答 α干扰素干扰素治疗伐昔洛韦丙型肝炎病毒环孢素泼尼松治疗超敏反应文

Migratory flight imposes oxidative stress in bats

在线全文

学校读者我要写书评

暂无评论

Current Zoology 2019年第2期65卷 147-153页

作者： david COSTANTiNi Oliver LINdECKE Gunars PETERSONS Christian C. voigt UMR 7221 CNRS/MNHN Museum National d'Histoire Naturelle Sorbonne Universites 7 rue Cuvier Paris 75005 France department of Biology University of Antwerp Universiteitsplein 1 Antwerp 2610 Belgium department of Evolutionary Ecology Leibniz Institute for Zoo and Wildlife Research Alfred-Kowalke-StraBe 17 Berlin 10315Germany lnstitute of Biology Freie Universitat Berlin Takustr. 6 Berlin 14195 Germany Faculty of Veterinary Medicine Latvia University of Life Sciences and Technologies K. Helmaqa & Jelgava LV 3004 Latvia

Many animal species migrate over long distances, but the physiological challenges of migration are poorly understood. It has recently been suggested that increased molecular oxidative damage might be one important challenge for migratory animals. We tested the hypothesis that autumn migration imposes an oxidative challenge to bats by comparing values of 4 blood-based markers of oxidative status (oxidative damage and both enzymatic and nonenzymatic antioxidants) between Nathusius' bats Pipistrellus nathusii that were caught during migration flights with those measured in conspecifics after resting for 18 or 24 h. Experiments were carried out at Pape Ornithological Station in Pape (Latvia) in 2016 and 2017. Our results show that flying bats have a blood oxidative status different from that of resting bats due to higher oxidative damage and different expression of both non enzymatic and enzymatic antioxidants (glutathione peroxidase). The differences in oxidative status markers varied betwee n sampli ng years and were in depende nt from in dividual body con dition or sex. Our work provides evidence that migratory flight might impose acute oxidative stress to bats and that resting helps animals to recover from oxidative damage accrued en route. Our data suggest that migrating bats and birds might share similar strategies of mitigating and recovering from oxidative stress.

关键词： antioxidants mammals oxidative damage stopover stress

Proteome-wide alterations in an industrial clavulanic acid producing strain of Streptomyces clavuligerus

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Synthetic and Systems Biotechnology 2017年第1期2卷 39-48页

作者： EserÜnsaldı Aslıhan Kurt-Kızıldogan Birgit voigt dorte Becher Gülay Ozcengiz department of Biological Sciences Middle East Technical University06800AnkaraTurkey department of Agricultural Biotechnology Ondokuz Mayıs University55139SamsunTurkey Institute of Microbiology Ernst-Moritz-Arndt-University of GreifswaldD-17487GreifswaldGermany

The usefulness of genetic/metabolic engineering for further improvement of industrial strains is subject of discussion because of the general lack of knowledge on genetic alterations introduced by iterative cycles of random mutagenesis in such *** industrial clavulanic acid(CA)-overproducer Streptomyces clavuligerus dEPA was assessed to understand proteome-wide changes that have occurred in a local industrial CA overproducer developed through succesive mutagenesis *** proteins that could be identified corresponded to 33 distinct ORFs for underrepresented ones and 60 ORFs for overrepresented *** CA biosynthetic enzymes were overrepresented in *** dEPA;carboxyethylarginine synthase(Ceas2),clavaldehyde dehydrogenase(Car)and carboxyethyl-arginine betalactam-synthase(Bls2)whereas the enzymes of two other secondary metabolites were underrepresented along with two important global regulators[two-component system(TCS)response regulator(SCLAV_2102)and TetR-family transcriptional regulator(SCLAV_3146)]that might be related with CA production and/or differentiation.g-butyrolactone biosynthetic protein AvaA2 was 2.6 fold underrepresented in *** *** levels of two glycolytic enzymes,2,3-bisphosphoglycerate-dependent phosphoglycerate mutase and phosophoglycerate kinase were found decreased while those of dihydrolipoyl dehydrogenase(E3)and isocitrate dehydrogenase,with two isoforms were found as significantly increased.A decrease of amino acid metabolism,methionine biosynthesis in particular,as well as S-adenosylmethionine synthetase appeared as one of the prominent mechanisms of success of *** dEPA strain as a prolific producer of *** levels of two enzymes of shikimate pathway that leads to the production of aromatic amino acids and aromatic secondary metabolites were also *** of the overrepresented stress proteins in *** dEPA included polynucleotide phosphorylase/polyadenylase(PNPase),ATP

关键词： Clavulanic acid Streptomyces clavuligerus Industrial strain Proteomics 2dE MALdI-TOF/MS

Cultured keratinocyte grafting on various biologic matrices

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

第二军医大学学报 1998年第S1期19卷 5-12页

作者： Stark GB△ Horch RE voigt M Kopp J Saied S Jiao XY Guest professor of Second Military Medical University From the department of Plastic and Hand Surgery and Tissue Engineering Lab. and valley TEC University of Freiburg Medical Center Freiburg Germany department of Plastic Surgery Changhai Hospital Second Military Medical University Shanghai 200433

１ＩｎｔｒｏｄｕｃｔｉｏｎＣｕｌｔｕｒｅｄｋｅｒａｔｉｎｏｃｙｔｅｓａｓｒｅｌａｔｉｖｅｌｙｄｉｆｅｒｅｎｔｉ－ａｔｉｅｄｓｈｅｅｔｇｒａｆｔｓｈａｖｅｉｍｐｒｏｖｅｄｔｈｅｃａｒｅｆｏｒｂｕｒｎｓａｎｄｏｔｈｅｒｗ... 详细信息

１ＩｎｔｒｏｄｕｃｔｉｏｎＣｕｌｔｕｒｅｄｋｅｒａｔｉｎｏｃｙｔｅｓａｓｒｅｌａｔｉｖｅｌｙｄｉｆｅｒｅｎｔｉ－ａｔｉｅｄｓｈｅｅｔｇｒａｆｔｓｈａｖｅｉｍｐｒｏｖｅｄｔｈｅｃａｒｅｆｏｒｂｕｒｎｓａｎｄｏｔｈｅｒｗｏｕｎｄｓ．Ｆｏｒｔｈｅｌａｓｔｄ...

关键词： keratinocyte culture tissue engineering skin substitute burns biomaterials

Chloroplast Proteins without Cleavable Transit Peptides： Rare Exceptions or a Major Constituent of the Chloroplast Proteome？

在线全文

学校读者我要写书评

暂无评论

Molecular Plant 2009年第6期2卷 1325-1335页

作者： Ute Armbruster Alexander Hertle Elina Makarenko Jessica Zuhlke Mathias Pribil Angela dietzmann Ivo Schliebner Elena Aseeva Elena Fenino Michael Scharfenberg Christian voigt dario Leister Lehrstuhl fur Botanik Department Biologie I Ludwig-Maximilians-Universit~t MQnchen Menzinger Str. 67 D-80638 Munchen Germany

Most chloroplast proteins （cp proteins） are nucleus-encoded, synthesized on cytosolic ribosomes as precursor proteins containing a presequence （cTP）, and post-translationally imported via the Tic/Toc complex into the organelle, where the cTP is removed. Only a few unambiguous instances of cp proteins that do not require cTPs （non-canonical cp proteins） have been reported so far. However, the survey of data from large-scale proteomic studies presented here suggests that the fraction of such proteins in the total cp proteome might be as large as -30%. To explore this discrepancy, we chose a representative set of 28 putative non-canonical cp proteins, and used in vitro import and Red Fluorescent Protein （RFP）-fusion assays to determine their sub-cellular destinations. Four proteins, including embryo defective 1211, glycolate oxidase 2, protein disulfide isomerase-like protein （PdII）, and a putative glutathione S-transferase, could be unambiguously assigned to the chloroplast. Several others （＇potential cp proteins＇） were found to be imported into chloroplasts in vitro, but failed to localize to the organelle when RFP was fused to their C-terminal ends. Extrapolations suggest that the fraction of cp proteins that enter the inner compartments of the organelle, although they lack a cTP, might be as large as 11.4% of the total cp proteome. Our data also support the idea that cytosolic proteins that associate with the cp outer membrane might account for false positive cp proteins obtained in earlier studies.

关键词： Chloroplast biology mitochondria organelle biogenesis/function protein targeting.

Three-dimensional problem of transient contact dynamics

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Science China Mathematics 1996年第10期39卷 1096-1105页

作者：范天佑 H.G.Hahn A.voigt Beijing Institute of Technology Beijing 100081 China University of Kaiserslautern d -67663 Kaiserslautern Germany

An analytic solution to three-dimensional problem of transient contact dynamics is developed, and a generalized Galin’s theorem is proved. Based on the theorem, contact displacements can be determined analytically when the given contact stresses are some quite general functions; in contrast to this, one can readily evaluate the corresponding contact stresses in analytic version when some quite general displacements are prescribed. The quite general form mentioned above means the prescribed quantities are any polynomials of x and y and any transient function of time. Numerical results for the contact displacements-time variation dearly demonstrate the effect of inertia induced by the dynamic stress.

关键词： transient dynamic contact three-dimensional problem generalized Galin’s theorem.

3d cardiac strain estimation using spatio-temporal elastic registration:in-vivo application

在线全文

学校读者我要写书评

暂无评论

3D cardiac strain estimation using spatio-temporal elastic r...

大豆粗蛋白对新生羔羊空肠粘膜生长发育的影响

2008 IEEE International Ultrasonics Symposium

作者： An Elen Andras Horvath Javier Ganame Brage Amundsen Jens-Uwe voigt Piet Claus Frederik Maes Jan d'hooge Catholic University of Leuven ESAT Catholic University of Leuven Cardiovascular DiseasesLeuven Norwegian University of Science and Technology Circulation and Medical Imaging

＜正＞Background,Motivation and Objective doppler-and speckle-tracking based deformation imaging of the heart has already proven its clinical value. despite promising findings,both methodologies remain limited as they...

关键词：

来源： cnki会议评论

在线全文

cnki会议

学校读者我要写书评

暂无评论

营养学报 2008年第3期30卷 290-293页

作者：何军 Schnhusen U. voigt J. 沈赞明南京农业大学农业部动物生理生化重点开放实验室 Research Institut efor the Biology of Farm Animals D-181196Germany

目的研究大豆粗蛋白(soybean protein,SP)取代部分乳源蛋白对新生羔羊空肠粘膜生长发育的影响,为大豆代乳品的合理利用和开发提供依据。方法17只7日龄羔羊随机分为SP组(n=8)和CS组(n=9),人工哺乳。SP组用大豆粗蛋白取代30%乳源蛋白;CS... 详细信息

目的研究大豆粗蛋白(soybean protein,SP)取代部分乳源蛋白对新生羔羊空肠粘膜生长发育的影响,为大豆代乳品的合理利用和开发提供依据。方法17只7日龄羔羊随机分为SP组(n=8)和CS组(n=9),人工哺乳。SP组用大豆粗蛋白取代30%乳源蛋白;CS组用与大豆蛋白等氮的酪蛋白取代,作为对照。每日哺乳2次,1W适应期。饲喂4W后宰杀取空肠组织样,扫描电镜观察空肠绒毛形态;以玻片刮取空肠各段粘膜用于蛋白质、RNA/dNA含量及碱性磷酸酶(ALP)含量测定。结果SP和CS两组羔羊采食量和体增重没有差别。SP组羔羊空肠绒毛明显萎缩;前段(127.2±4.6vs143.6±7.3mg/g粘膜,P=0.07)和中段(111.2±6.3vs132.7±8.5mg/g,P=0.06)粘膜总蛋白含量有降低的趋势;前段粘膜RNA/dNA(1.40±0.10vs1.68±0.08)及蛋白质/dNA(41.3±3.2vs51.5±2.8)比率均显著低于CS组(P<0.05);各段粘膜ALP含量均显著下降(P<0.05)。结论短期以大豆蛋白取代30%的乳源蛋白饲喂新生羔羊,延缓空肠粘膜生长和发育,但未影响摄食和体增重。

关键词：大豆蛋白酪蛋白空肠粘膜碱性磷酸酶羔羊