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Hyponatremia in the acute phase of spinal cord trauma: Review

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Journal of Acute Disease 2018年第3期7卷 103-107页

作者： Luis Rafael Moscote Salazar Amit Agrawal Guru Dutta Satyarthee Huber S.Padilla-Zambrano Boris vladimir Cabrera-Nanclares Romario Mendoza-Flórez Samer Hoz Alexis Narvaez-Rojas Universidad de Cartagena Cartagena de IndiasColombia Department of Neurosurgery Narayna Medical College HospitalChinthareddypalemNellore-524003Andhra PradeshIndia All India Institute of Medical Sciences New DelhiIndia School of Medicine.Centro de Investigaciones Biomédicas(CIB).Cartagena Neurotrauma Research Group research line.Faculty of Medicine-University of Cartagena CartagenaColombia Neurosurgery Teaching Hospital BaghdadIraq Universidad Nacional Autonoma de Managua Nicaragua

Hyponatremia is a common electrolyte disturbance usually observed in neurosurgical patients undergoing surgical management of traumatic, as well as, nontraumatic intracranial pathology. The spinal cord trauma is also associated with occasional development of such hyponatremia;it usually occurs within the first two-weeks of the injury. Hyponatremia can lead to alterations of consciousness, convulsions, coma, cardiac arrhythmias and on rare occasions, death. Authors present a practical oriented review of the literature.

关键词： Hyponatremia Serum sodium Spinal cord trauma Neurotrauma Injury

The Role of Atherosclerosis and Inflammation in the Development of Descending Aortic Aneurysms: Special Aspects of Medical Correction

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Health 2016年第13期8卷 1335-1348页

作者： vladimir Petrovich Krylov Nikolay Andreevich Mana Leonid Petrovich Titov Valentina Nikolaevna Gayduk Leonid Ivanovich Reut Nadezhda vladimirovna Mankevich Alexander Stanislavovich Zhigalcovitch Aleksey Leonidovich Smolyakou Gennady Adolfovich Popel Roman Nikolaevich Pyzhyk Republican Scientific and Practical Centre “Cardiology” Ministry of Health of Belarus Minsk Belarus Republican Scientific and Practical Centre “Epidemiology and Microbiology” Ministry of Health of Belarus Minsk Belarus Belarusian Medical Academy of Post-Graduate Education Minsk Belarus

Modern medicine has achieved much progress in the field of medical and surgical repair of a variety of disorders. It is especially true for the early stages of treatments. In long-term period, however, instead of recovery, we frequently observe progressive regression, which completely annuls all our efforts. Moreover, the algorithm used to correct acute process may sometimes be detrimental to organs and tissues. Such situation is also frequent in the treatment of atherosclerotic descending aortic aneurysms (DAA). This is because the successful medical and even surgical repair to prevent aneurysm rupture in long-term period may trigger some detrimental processes in other regions thus producing negative results of the treatment. The present article doesn’t aim to prove some provisions in DAA clinical picture, atherosclerosis and inflammatory states. But we have faced some systematicity at these clinical implications which are absolutely not specified in literature. We have managed to find an explanation for this thing making a scrupulous analysis of nonsurgical sources. Comparing them with our observations, we have found out that aseptic and septic inflammation of connective tissue, probably, is a key component in the formation of DAA disregarding of which correction of dyslipidemia may lead to negative results. We are looking for in-depth research and discussion.

关键词： Aneurism Formation Atherosclerosis and Inflammation Aortic Aneurisms

Theory, Practice and Prospection of Si Fertilizer

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Agricultural Science & Technology 2013年第3期14卷 498-502,506页

作者：弗拉基米尔.马基琴科夫魏晓刘代平埃琳娜.伯查妮科娃俄罗斯科学院基础生物研究所俄罗斯莫斯科普希诺142290 湖南省经济地理研究所湖南长沙410004 俄罗斯科学院物理化学和生物研究所俄罗斯莫斯科谱希诺142290

This paper summarizes the theory of the chemical and physical properties of Si, soil classification for Si soil test and Si fertilizer types, effect of Si fertilizer on plant and soil etc., and proves that Si fertilizer can increase the P nutrition, yield and quality, resistance to any biotic and abiotic stress ability, reduce the toxici- ty of heavy metals of plants and improve the water fertilizer retention of soil by practice; also points out that the best source for Si fertilizers is natural rich Si ma- terials. At last, it gives the prospection about the application of Si fertilizer in the sustainable and organic agriculture.

关键词： Si fertilizer Theory Practice Prospection

A new form of Miscanthus (Chinese silver grass, Miscanthus sinensis—Andersson) as a promising source of cellulosic biomass

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Advances in Bioscience and Biotechnology 2010年第3期1卷 167-170页

作者： vladimir K. Shumny Sergey G. Veprev Nikolay N. Nechiporenko Tatiana N. Goryachkovskaya Nikolay M. Slynko Nikolay A. Kolchanov Sergey E. Peltek 不详

The Far East population of Miscanthus sinensis (Andersson) was introduced into the West Siberia conditions. There was distinguished a form with a modified structure of the rootage which forms long shoots with leader buds and rapidly colonizes soil, thus forming a continuous and flat (without tussocks) plantation of miscanthus. It is shown that using usual agrotechnologies, it is possible to obtain 10-15 tons of dry biomass of high quality cellulose (about 40%) per ha/year.

关键词： Cellulose Lignin Biomass Cellulosic Biomass Miscanthus sinensis Vegetative Reproduction of Plants

A pain-inducing centipede toxin targets the heat machinery of nociceptor TRPV1

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A pain-inducing centipede toxin targets the heat machinery o...

Nonlinear Polarizability of Erythrocytes in Non-Uniform Alternating Electric Field

第12届生物毒素研究及医药应用学术大会

作者： Shilong Yang Fan Yang Ningning Wei Jing Hong Bowen Li Lei Luo Mingqiang Rong vladimir Yarov-Yarovoy Jie Zheng KeWei Wang Ren Lai Key Laboratory of Animal Models and Human Disease Mechanisms Chinese Academy of SciencesKunming Institute of Zoology University of Chinese Academy of Sciences Department of Physiology and Membrane Biology University of California Department of Neurobiology Neuroscience Research InstitutePeking University Health Science Center College of Biological Science and Engineering Fuzhou University Department of Molecular and Cellular Pharmacology PKU-IDG/McGovern Institute for Brain ResearchPeking University School of Pharmaceutical Sciences Department of Pharmacology Qingdao University

The Capsaicin receptor ion channel TRPV1 is a polymodal nociceptor that responds to heat with exquisite sensitivity through an unknown *** we report the identification of a toxin,RhTx,from the venom of Chinese red-headed centipede that potently activates TRPV1 to produce excruciating *** is a 27-amino acid small peptide that forms a compact polarized molecule with very rapid binding reaction and high affinity for *** show that RhTx targets the channel’s heat activation machinery to cause powerful activation at normal body *** RhTx-TRPV1 interaction is mediated by the toxin’s highly charged C-terminus,which associates tightly to the charge-rich outer pore region of the channel where it can directly interact with the pore helix and *** findings demonstrate that RhTx binding to the outer pore can induce TRPV1 heat activation,therefore providing crucial new structural information on the heat activation machinery.

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Open Journal of Biophysics 2014年第3期4卷 97-103页

作者： Konstantin V. Generalov vladimir M. Generalov Alexander S. Safatov Alexander G. Durymanov Galins A. Buryak Margarita V. Kruchinina Mikhail I. Voevoda Andrey A. Gromov Federal Budget Research Institution State Research Center of Virology and Biotechnology Vector Koltsovo Novosibirsk Region Russian Federation Federal State Budgetary Institution of Internal and Preventive Medicine Siberian Branch under the Russian Academy of Medical Sciences Novosibirsk Russian Federation

Nonlinear polarizability of erythrocytes in non-uniform alternating electric field (NUAEF) was proved theoretically and experimentally by dielectrophoresis method. The paper presents experimental evidence of the nonlinear polarizability of erythrocytes in the non-uniform alternating electric field. The rotation of erythrocyte around its own axis at more than one revolution per second in the non-uniform alternating electric field in the frequency range and the electric field intensity?is the evidence of its nonlinear polarizability. The theoretical analysis of the density of electric charges capable of overcoming the membrane potential was carried out on the basis of statistical mechanics, the thermal equilibrium in which the particle stays. The nonlinear polarizability of the erythrocyte emerges if the voltage on the membrane exceeds?, which was theoretically proved. The alternating electric field from the donor erythrocyte with the amplitude exceeding forms the constant component of the current? in the cytoplasm of the recipient erythrocyte whose energy can be considered as a signal one. The nonlinear equivalent electric circuit of the cell was proposed.

关键词： Dielectrophoresis Polarizability Rotation Erythrocyte Nonlinearity

A Dual Effect of Au-Nanoparticles on Nucleic Acid Cholesteric Liquid-Crystalline Particles

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Journal of Biomaterials and Nanobiotechnology 2011年第4期2卷 461-471页

作者： Yuri M. Yevdokimov Sergey G. Skuridin Victor I. Salyanov vladimir I. Popenko Victor M. Rudoy Ol,ga V. Dement′eva Eleonora V. Shtykova 不详

Au-nanoparticles (size about 2 nm, but not 5 or 15 nm) are capable of effectively incorporating into quasinematic layers of particles of cholesteric liquid-crystalline dispersion formed by double-stranded nucleic acid molecules of various families (DNA and poly(I)xpoly(C)). This Au-size-dependent process is accompanied by a decrease in amplitudes of abnormal bands in the CD spectra specific to initial cholesteric liquid-crystalline dispersions and simultaneously by an appearance of plasmon resonance band in visible absorption spectrum. The study of properties of particles of cholesteric liquid-crystalline dispersion treated with Au-nanoparticles by means of various physico-chemical methods demonstrates that incorporation of Au-nanoparticles into quasinematic layers of these particles results in two effects: i) it facilitates reorganization of the spatial cholesteric structure of particles, and ii) it induces the formation of Au-clusters in the content of particles. It is not excluded that these effects represent a possible reason for genotoxicity of Au-nanopar- ticles.

关键词： Double-Stranded Nucleic Acids Gold Nanoparticles Nucleic Acid Liquid-Crystalline Dispersions Circular Dichroism Structure of Lyotropic Liquid Crystals of (Bio)Polymers Genotoxity of Nanoparticles

Evaluation of Natural Radioactivity Levels for Structural Material Used in the Construction of the Neutrino Detector

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World Journal of Nuclear Science and Technology 2015年第1期5卷 43-56页

作者： vladimir G. Zinovyev Anatolii P. Serebrov Ivan A. Mitropolsky Yuriy E. Loginov Georgiy I. Shulyak Tatyana M. Tyukavina Sergey L. Sakharov Anatoly V. Chernyj Neutron Research Department National Research Centre “Kurchatov Institute” B.P. Konstantinov Petersburg Nuclear Physics Institute Gatchina Russia

In this work, the evaluation of natural radioactivity and spontaneous fission rates was performed for 8 nuclides from the natural radioactive 238U, 235U and 232Th decay chains. For this purpose, three samples of structural materials of the neutrino detector, i.e. aluminum, titanium and glass were analyzed by gamma spectroscopy and by neutron activation analysis to quantify a specific radioactivity of the samples. According to the results of this investigation, glass and aluminum samples have maximum values of the mean uranium concentrations 7.3(7) × 10-4% and 3.1(6) × 10-5%, respectively, while the lowest value for mean concentration of the uranium was found in titanium samples to be 4.7(3) × 10-6%. Aluminum sample had maximum values of the mean thorium concentrations, 2.5(8) × 10-3%, while the lowest value for mean concentration of the thorium was found in titanium samples to be 6.2(3) × 10-7%.

关键词： Spontaneous Fission Radioactive Decay Chain α-Decay Radionuclide Branching Factor

Molybdenum Carbide Nano-Powder for Production of Mo-99 Radionuclides

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World Journal of Nuclear Science and Technology 2012年第2期2卷 58-63页

作者： vladimir D. Risovany Konstantin V. Rotmanov Genady I. Maslakov Yury D. Goncharenko Grigory A. Shimansky Aleksandr I. Zvir Irina M. Smirnova Irina N. Kuchkina Joint Stock Company State Scientific Center—Research Institute of Atomic Reactors Dimitrovgrad Russia

At present, there are two ways to produce 99Mo in a reactor: 1) fission process—from U fission product by reaction 235U (n, f) 99Mo and 2) activation process—by radiation capture reaction 98Mo (n, γ) 99Mo. This paper presents the results of experiments performed with molybdenum carbide nano-powder to produce 99Mo. These results show the implementation of the above idea in practice.

关键词： Carbide Nano-Powder Molybdenum-99 Activation Process Fission Process