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BIERMER’s Disease: About 4 Cases Diagnosed at Regional University Hospital of Ouahigouya (Chur/Ohg) and Literature Review

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Open Journal of Gastroenterology 2024年第9期14卷 322-329页

作者： Zanga Damien Ouattara Stève Léonce Zoungrana Saïdou Santi Emeline Agathe Carama Fabien Dembele Bafima Désiré Diarra Alain Bougouma Department of Gastroenteroly Ouahigouya Regional University Hospital Ouahigouya Burkina Faso Department of Neurology Bogodogo University Hospital Ouagadougou Burkina Faso Department of Gastroenterology Yalgado Oudraogo University Hospital Center Ouagadougou Burkina Faso

Megaloblastic pernicious anemia is an autoimmune disorder, considered rare in African context. The objective of this study was to report four clinical cases collected at the CHUR/OHG, and to review the literature. The study population consisted of two men and two women. The clinical manifestations were mainly neurological and hematological. The neurological signs were mainly paresthesia. One patient presented memory problems. On the biological level, macrocytic anemia and vitamin B12 deficiency were reported in two cases prior to treatment while the other two without serological assay of vitamin B12 were put on trial treatment. Anti-intrinsic factor antibodies were positive in three patients. The Schilling test was not used. Upper gastrointestinal endoscopy revealed atrophic fundic gastritis in all four patients who received treatment through intramuscular injection of hydroxocobalamin (vitamin B12). The evolution was favorable after one month of treatment in all cases. The literature review is dominated by clinical case reports, the largest cohorts of which are from the Maghreb.

关键词： Anemia Pernicious Megaloblastic Vitamin B12

Nurses’perceptions about neonatal intensive care units providing family-centered care are associated with skin-to-skin contact implementation

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Pediatric Investigation 2024年第1期8卷 61-65页

作者： Marilyn Aita Gwenaëlle De Clifford-Faugère Geneviève Laporte Sébastien Colson Nancy Feeley Faculty of Nursing Universitéde MontréalMontrealCanada CHU Sainte-Justine Research Centre MontrealCanada Quebec Network on Nursing Intervention Research MontrealCanada Faculty of Medical and Paramedical Sciences CEReSSAix-Marseille UniversitéMarseilleFrance Ingram School of Nursing McGill UniversityMontrealCanada Centre for Nursing Research and Lady Davis Institute Jewish General HospitalMontrealCanada

Skin-to-skin contact(SSC)consists of positioning the diaper-clad infant against the parent’s chest and is considered a nursing practice rooted in family-centered care(FCC).1 SSC implies simultaneous parental presence and helps to facilitate their involvement from the earliest hours of their preterm infants’lives as this intervention is delivered by parents.1 FCC has gained worldwide popularity in recent years to promote parental presence and active participation of parents in care during neonatal intensive care units(NICUs)hospitalization.2 Both practices relate to developmental care(DC),which regroups specific interventions aimed at reducing stress and improving infant neurological development.

关键词： centered gained Skin

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物理刺激响应型蠕虫状胶束研究进展

精细化工 2024年

作者： (2)捕集新原理与技术研究中心 (2)捕集新原理与技术研究中心 (2)捕集新原理与技术研究中心 (2)捕集新原理与技术研究中心天府永兴实验室CO

物理刺激响应型蠕虫状胶束是指在光、温度、磁场、超声等物理因子刺激下，微观结构发生明显改变的蠕虫状胶束体系，具有非侵入性、可远程操控、环境友好等诸多优点，契合当代绿色环保的发展理念。首先，综述了物理刺激响应型蠕虫状胶束... 详细信息

物理刺激响应型蠕虫状胶束是指在光、温度、磁场、超声等物理因子刺激下，微观结构发生明显改变的蠕虫状胶束体系，具有非侵入性、可远程操控、环境友好等诸多优点，契合当代绿色环保的发展理念。首先，综述了物理刺激响应型蠕虫状胶束〔光响应型、温度响应型、外力场（磁、电、超声）响应型、多重物理刺激响应型蠕虫状胶束〕的构筑策略、响应机制及流变性质。然后，阐述了物理刺激响应型蠕虫状胶束的应用进展及取得的成果。目前，物理刺激响应型蠕虫状胶束的研究主要侧重于体系构建和基础理论层面，构筑方式仍以低效率的试错法为主，而相关应用开发还处于实验室阶段。最后，指出未来物理刺激响应型蠕虫状胶束的开发应注重与大数据模拟、机器学习等人工智能技术的结合，探索出物理刺激响应型蠕虫状胶束的高效、低廉、规模化合成方法，并深入探究其在现场实施中的性能变化与响应特性，为其规模化生产与应用提供理论依据和技术支撑。

关键词：蠕虫状胶束黏弹性物理刺激响应表面活性剂流变特性

Exploring conservative management for cervical intraepithelial neoplasia grade 2 in organised cervical cancer screening programmes:a multicentre study in Italy

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Family Medicine and Community Health 2024年第S02期12卷 1-7页

作者： Silvia Gori Helena Frayle Alessio Pagan Marika Soldà Cesare Romagnolo Egle Insacco Licia Laurino Mario Matteucci Giuseppe Sordi Enrico Busato Manuel Zorzi Tiziano Maggino Annarosa Del Mistro CIN2 study Working Group veneto Institute of Oncology IOV-IRCCS PadovaItaly Local Health Unit Marca Trevigiana TrevisoItaly Local Health Unit Serenissima VeneziaItaly Obstetrics and Gynecology Azienda Ospedale UniversitàPadovaItaly Local Health Unit Scaligera VeronaItaly veneto Tumour Registry Azienda ZeroPadovaItaly 不详

Cervical intraepithelial neoplasia grade 2(CIN2)lesions may regress spontaneously,offering an alternative to immediate treatment,especially for women of childbearing age(15–45 years).We conducted a prospective multicentre study on conservative CIN2 management,with semiannual follow-up visits over 24 months,biomarkers’investigation and treatment for progression to CIN3+or CIN2 persistence for more than 12 ***,we assess women’s willingness to participate and adherence to the study *** study was set in population-based organised cervical cancer *** April 2019 to October 2021,640 CIN2 cases were diagnosed in women aged 25–64 participating in the screening *** to our predefined inclusion and exclusion criteria,228(35.6%)women were not eligible;93(22.6%)of the 412 eligible refused,and 319(77.4%)were *** for personal reasons(ie,desire to become pregnant,anxiety,difficulty in complying with the study protocol)and external barriers(ie,residence elsewhere and language problems)accounted for 71%and 17%,*** 9%expressed a preference for *** primary ineligibility factor was the upper age limit of 45 *** enrolment,12(4%)women without evidence of progression requested treatment,125(39%)were lost to follow-up(mostly after 6–12 months)and 182(57%)remained ***,40%of enrolees did not fully adhere to the protocol,whereas only 5%(20/412)of the eligible women desired *** study demonstrates a good acceptance of conservative management for CIN2 lesions by the women,supporting its implementation within cervical screening programmes.

关键词： cervical conservative centre

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2型糖尿病患者卒中预防及血糖管理专家共识

中华内科杂志 2024年第7期63卷 649-659页

作者：《2型糖尿病患者卒中预防及血糖管理专家共识》编写委员会陈莉明母义明不详天津医科大学朱宪彝纪念医院内分泌科天津300134 解放军总医院第一医学中心内分泌科北京100853

糖代谢异常与卒中关系密切,对卒中的发生、发展及预后均有不良影响。良好的血糖控制对改善卒中预后具有重要意义。部分降糖药物能够减少2型糖尿病患者卒中的发生及复发风险。2型糖尿病合并卒中患者应控制血压、血脂,合理应用抗血小板药... 详细信息

糖代谢异常与卒中关系密切,对卒中的发生、发展及预后均有不良影响。良好的血糖控制对改善卒中预后具有重要意义。部分降糖药物能够减少2型糖尿病患者卒中的发生及复发风险。2型糖尿病合并卒中患者应控制血压、血脂,合理应用抗血小板药物。共识专家组基于循证医学证据和临床实践,并经过多次讨论最终形成本共识,以期为临床提供参考。

关键词：糖尿病 2型卒中预防血糖管理专家共识

拥抱城市法国Groupe Galia办公楼

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室内设计与装修 2024年第1期 56-61页

作者： [法国]h2o architects 小麦(编译) h2o architects

Groupe Galia办公楼位于巴黎11区的Villadu Clos-de-Malevart,原建筑改造前是一家汽车销售店。该大楼面朝内街且独立于周围的建筑,因此在这个建筑密集的区域内几乎是一个完全不透明的体量。经过设计团队简单却精心的策划干预,使得这座... 详细信息

Groupe Galia办公楼位于巴黎11区的Villadu Clos-de-Malevart,原建筑改造前是一家汽车销售店。该大楼面朝内街且独立于周围的建筑,因此在这个建筑密集的区域内几乎是一个完全不透明的体量。经过设计团队简单却精心的策划干预,使得这座翻新建筑与城市环境重新建立起了联系。

关键词：建筑改造建筑与城市办公楼建筑密集设计团队

Chinese expert consensus on the clinical application of sodium-glucose cotransporter 2 inhibitors in patients with chronic kidney disease

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Chinese Medical Journal 2024年第11期137卷 1264-1266页

作者： The Expert Group of Chinese Expert Consensus on the Clinical Application of Sodium-glucose Cotransporter 2 Inhibitors in Patients with Chronic Kidney Disease Fan Fan Hou Chuanming Hao Min Zhang Chuanming Hao 不详 Department of Nephrology Nanfang HospitalSouthern Medical UniversityGuangzhouGuangdong 510515China Division of Nephrology Huashan HospitalFudan UniversityShanghai 200040China

The prevalence of chronic kidney disease(CKD)in China was 8.2%in 2018-2019.[1]CKD may progress to end-stage kidney disease(ESKD),necessitating kidney replacement treatment such as dialysis or kidney transplantation,[2]which imposes a substantial burden on both family and ***,patients with CKD have a high risk of comorbidities including cardiovascular diseases.[3]The risk of death rises as the estimated glomerularltration rate(eGFR)declines.[3]A substantial portion of CKD patients die,primarily from cardiovascular events,before reaching the stage requiring dialysis.[3]As such,delaying the progression of CKD and reducing cardiovascular events are key elements in patient *** recent years,important progress has been made in the cardiorenal protection of patients with ***cally,the advent of sodium-glucose cotransporter 2(SGLT2)inhibitors has provided a new and important approach for the treatment of CKD.

关键词： kidney patients dialysis

Knowledge Enhancement and Question-Answering of Metallurgical Industry Based on Generative AI Large Models

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Knowledge Enhancement and Question-Answering of Metallurgica...

第35届中国过程控制会议

作者： Ronghui Liu Hao Ren Wei Cui Chunhua Yang Weihua Gui Xiaojun Liang Peng Tang2Jie Han School of Future Technology South China University of Technology Industrial Intelligence Basic Studio Peng Cheng Laboratory

The metallurgical industry, characterized as a typical process industry, exhibits features such as frequent changes in raw material compositions, severe fluctuations in operational conditions, and complex physicochemical reaction *** attributes result in the knowledge within the field being extensive and intricate, making centralized management and effective application challenging. Addressing these challenges, this paper introduces a method that leverages the expertise of local knowledge bases and the powerful semantic understanding and text generation capabilities of Generative AI Large Models(GLM) to enhance metallurgical industry knowledge and facilitate Question-Answering(Q&A). The approach includes: initially cleaning and deduplicating raw data from industrial literature, production manuals, and briefings to establish a local knowledge base for the metallurgical industry. Subsequently, the contents of the knowledge base are embedded using Word2vec technology to create a local vector library of knowledge. FAISS(Facebook AI Similarity Search) technology is then utilized to search for knowledge vectors similar to specific industrial problems. Finally, selected question vectors and knowledge base vectors are integrated into input prompts for the GLM, which then produces accurate and coherent answers. Experimental results indicate that this method significantly improves the accuracy of Question-Answering in the metallurgical industry.

关键词： Generative AI Knowledge Enhancement Large Language Models Metallurgical Industry Question-Answering

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大数据视域下烟草企业营销工作优化路径

商界（评论） 2024年第9期 0191-0193页

作者：杨傲梅1 杨童舒2 湖北中烟工业有限公司襄阳卷烟厂1 襄阳市融资担保集团2