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International Journal of Geosciences 2010年第2期1卷 58-65页

作者： Montrasio Lorella valentino roberto Chiara Quintavalla 不详

For the development of alert systems for soil slip occurrence, it is important to evaluate the degree of saturation of shallow soils (Sr) over wide areas. Taking into account the possibility to estimate spatial and temporal variation of soil moisture using remote sensing techniques, a possible correlation between Sr and the daily output of a sequential data assimilation system called ACHAB (Assimilation Code for HeAt and moisture Balance) has been studied. ACHAB is based on integrated use of remotely sensed land surface temperature (LST) and common data on meteorological forcing such as air temperature, wind-speed and incident solar radiation. The aim of this study is to understand if it is possible to use ACHAB output (a daily value of evaporative fraction for the whole Italian territory) to define the parameter Sr that could be introduced in a simplified model for the description of soil slip triggering mechanisms on territorial scale.

关键词： Degree of Saturation Soil Slip Satellite Observations

Coronal plane deformity around the knee in the skeletally immature population:A review of principles of evaluation and treatment

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World Journal of Orthopedics 2022年第5期13卷 427-443页

作者： valentino Coppa Mario Marinelli roberto Procaccini Danya Falcioni Luca Farinelli Antonio Gigante Clinical Orthopaedics Department of Clinical and Molecular SciencesUniversitàPolitecnica delle MarcheAncona 60121Italy

Coronal plane deformity around the knee,also known as genu varum or genu valgum,is a common finding in clinical practice for pediatricians and *** deformities can be physiological or *** untreated,pathological deformities can lead to abnormal joint loading and a consequent risk of premature *** aim of this review is to provide a framework for the diagnosis and management of genu varum and genu valgum in skeletally immature patients.

关键词： Genu varum Genu valgum Pediatric deformity Knee deformity Guided growth Osteotomy Lower limb deformity

Identification of Characteristic Values in Impulse-Based Processes Using Small Specimens

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Nanomanufacturing and Metrology 2022年第3期5卷 310-323页

作者： Tobias valentino Tim Radel BIAS-Bremer Institut Fur Angewandte Strahltechnik GmbH Klagenfurter StraBe 528359 BremenGermany

Suitable approaches are needed for rapid and cost-efficient materials ***-throughput experimentation reduces the identification time of suitable material *** approach is to use small specimen geometries to save additional production ***,research is continuously being conducted on a new hardness test based on laser-induced shock *** far,characteristic values from the induced indentations have been extracted,which correlate with hardness and tensile ***,the indentation result varies in dependence of the specimen size and *** condition hinders the correlation between characteristic values and material ***,the goal was to induce similar indentation results to minimum specimen ***,different mounting materials and methods were *** created indentations were compared with those induced in large *** mounting parameters were derived from the ***,small specimens can be used for material characterization by considering these mounting parameters.

关键词： Mounting Stiffness Coefficient of restitution Forming efficiency Measuring instrument TEA-CO_(2)laser

The multifaceted PDCD10/CCM3 gene

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Genes & Diseases 2021年第6期8卷 798-813页

作者： Mariaelena valentino Elisabetta Dejana Matteo Malinverno The FIRC Institute of Molecular Oncology(IFOM) Milan1620139Italy Department of Oncology and Haemato-Oncology University of MilanMilan720122Italy Vascular Biology Department of ImmunologyGenetics and PathologyUppsala UniversityUppsalaSE-75105Sweden

The programmed cell death 10(PDCD10)gene was originally identified as an apoptosis-related gene,although it is now usually known as CCM3,as the third causative gene of cerebral cavernous malformation(CCM).CCM is a neurovascular disease that is characterized by vascular malformations and is associated with headaches,seizures,focal neurological deficits,and cerebral *** PDCD10/CCM3 protein has multiple subcellular localizations and interacts with several multi-protein complexes and signaling *** PDCD10/CCM3 governs many cellular functions,which include cell-to-cell junctions and cytoskeleton organization,cell proliferation and apoptosis,and exocytosis and *** its central role in the maintenance of homeostasis of the cell,dysregulation of PDCD10/CCM3 can result in a wide range of altered cell *** can lead to severe diseases,including CCM,cognitive disability,and several types of ***,we review the multifaceted roles of PDCD10/CCM3 in physiology and pathology,with a focus on its functions beyond CCM.

关键词： Cancer Cell signaling Cell-cycle Neurovascular unit PDCD10/CCM3

Contrasting responses of native and alien plant species to soil properties shed new light on the invasion of dune systems

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Journal of Plant Ecology 2020年第6期13卷 667-675页

作者： Stefano Vitti Elisa Pellegrini valentino Casolo Giacomo Trotta Francesco Boscutti Department of Life Sciences University of TriesteVia L.Giorgieri 1034127 TriesteItaly Department of Agricultural FoodEnvironmental and Animal SciencesUniversity of Udinevia delle Scienze 91Udine 33100Italy Department of Biology University of CopenhagenUniversitetsparken 42100 KøbenhavnØDenmark

Aims Among terrestrial ecosystems,coastal sandy dunes are particularly prone to alien plant *** studies related the invasion of dune habitats to anthropic causes,but less is known about the role of soil properties and plant traits in plant *** this study,we tested the relationships between soil features and alien plant invasion in dune systems,focusing on the interplay between soil nutrients,soil salinity and plant functional *** Study sites were sandy barrier islands of the Marano and Grado lagoon(northern Adriatic Sea).One hundred plots(4 m×4 m)were selected within 10 areas according to the main habitats occurring along the ecological gradient of dune system(foredune,backdune and saltmarsh).In each plot,we recorded all plant species occurrence and abundance and we collected a soil *** each soil sample,soil texture,conductivity(as proxy of soil salinity),organic carbon and nitrogen content were analyzed and related to the species number and cover of native and alien *** of main reproductive and vegetative functional traits among habitats was also analyzed for both alien and native *** Findings Soil properties were strongly related to overall plant diversity,by differently affecting alien and native species *** backdune,the most invaded habitat,a high soil conductivity limited the number of alien species,whereas the content of soil organic carbon increased along with alien plant abundance,suggesting also the occurrence of potential feedback processes between plant invasion and *** found a significant convergence between native and alien plant functional trait spectra only in backdune habitat,where environmental conditions ameliorate and plant competition *** findings suggest that in harsh conditions only native specialized plants can thrive while at intermediate conditions,soil properties gradient acts in synergy with plant traits to curb/facilitate alien plant richness.

关键词： invasive alien species functional traits soil nutrients plant communities dune system

Spatial-controlled etching of coordination polymers

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Chinese Chemical Letters 2021年第2期32卷 635-641页

作者： Qi Dang Yucen Li Wei Zhang Yusuf valentino Kaneti Ming Hu Yusuke Yamauchi School of Physics and Electronic Science.East China Normal University Shanghai 200241China International Center for Materials Nanoarchitectonics(MANA) National Institute for Materials Science(NIMS)Ibaraki 305-0044Japan School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology(A1BN) The University of QueenslandQueensland 4072Australia Department of Plant and Environmental New Resources Kyung Hee University.Gyeonggi-do 446-701South Korea

Nanoarchitectonics provide versatile opportunities for modifying the properties of coordination polymers(CP) other than molecular ***-controlled etching focuses on the controlled disassembly of the *** etching method provides an excellent opportunity for tailoring the properties and functions of the ***,we discuss the mechanism for controlled etching of the CPs and summarized the two main strategies utilized so *** examples are illustrated to demonstrate recent developments in this ***,advantages of the etched CPs are summarized in several important applications,including energy storage,catalysis and nanomedicine.

关键词： Coordination polymer Metal-organic frameworks Etching Hollow structure Sodium ion battery Catalysis Nanomedicine

When important steps for a reliable Meta-analysis are missing: the bevacizumab versus ranibizumab case

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International Journal of Ophthalmology(English edition) 2015年第1期8卷 204-205页

作者： valentino Conti Mauro Venegoni Ugo Moretti Corrado Barbui Regional Pharmacovigilance Centre of Lombardy Regional Pharmacovigilance Centre of Veneto Section of Psychiatry Department of Public Health and Community MedicineUniversity of VeronaPoliclinico GB Rossi

Dear Sir,W e have read with attention and interest the systematic review on the effectiveness and safety of bevacizumab and ranibizumab in the treatment of age-related macular degeneration(AMD)written by Zhang et al[1]and published on number of April 2014 of International Journal of *** authors,who collected data from 4randomized clinical trials(RCTs)and 11 observational

关键词： the bevacizumab versus ranibizumab case When important steps for a reliable Meta-analysis are missing than

Integrin-targeting with peptide-bioconjugated semiconductor-magnetic nanocrystalline heterostructures

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Nano Research 2016年第3期9卷 644-662页

作者： Gianpiero Valente Nicoletta Depalo Ivan de Paola Rosa Maria lacobazzi Nunzio Denora valentino Laquintana roberto Comparelli Emiliano Altamura Tiziana Latronico Michele Altomare Elisabetta Fanizza Marinella Striccoli Angela Agostiano Michele Saviano Annarita Del Gatto Laura Zaccaro Maria Lucia Curri Universita degli Studi di Bari Aldo Moro Dipartimento di Chimica Via Orabona 4 70125 - Bari Italy Istituto per i Processi Chimico-Fisici-CNR UOS Bari Via Orabona 4 70125 - Bari Italy Istituto di Biostrutture e Bioimmagini-CNR Via Mezzocannone 16 80134 - Napoli Italy Universita degli Studi di Bari Aldo Moro Dipartimento di Farmacia - Scienze del Farmaco Via Orabona 4 70125 - Bari Italy Universita degli Studi di BariAIdo Moro Dipartimento di Bioscienze Biotecnologie e Biofarmaceutica Via Orabona 4 70125 - Bari Italy lstituto di Cristallografia-CNR Via Amendola 122/0 70126 Bari Italy

Binary asymmetric nanocrystals （BNCs）, composed of a photoactive TiO2 nanorod joined with a superparamagnetic γ-Fe203 spherical domain, were embedded in polyethylene glycol modified phospholipid micelle and successfully bioconjugated to a suitably designed peptide containing an RGD motif. BNCs represent a relevant multifunctional nanomaterial, owing to the coexistence of two distinct domains in one particle, characterized by high photoactivity and magnetic properties, that is particularly suited for use as a phototherapy and hyperthermia agent as well as a magnetic probe in biological imaging. We selected the RGD motif in order to target integrin expressed on activated endothelial cells and several types of cancer cells. The prepared RGD-peptide/BNC conjugates, comprehensively monitored by using complementary optical and structural techniques, demon- strated a high stability and uniform dispersibility in biological media. The cytotoxicity of the RGD-peptide/BNC conjugates was studied in vitro. The cellular uptake of RGD-peptide conjugates in the cells, assessed by means of two distinct approaches, namely confocal microscopy analysis and emission spectroscopy determination in cell lysates, displayed selectivity of the RGD-peptide-BNC conjugate for the cw]33 integrin. These RGD-peptide-BNC conjugates have a high potential for theranostic treatment of cancer.

关键词： nanocrystallineheterostructures photoactive semiconductor magnetic nanostructure cyclic RGD peptide αvβ3 integrin active targeting

Spontaneous gastric hematoma as a rare cause of acute abdomen:A case report

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World Journal of Clinical Cases 2023年第36期11卷 8551-8556页

作者： Ivan Budimir MirnaŽulec Ksenija Eljuga MarcelŽidak valentino Lisek Department for Plastic and Reconstructive Surgery University Hospital DubravaZagreb 10000Croatia Zagreb School of Medicine University of ZagrebZagreb 10000Croatia Faculty of Medicine Osijek Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia Department of Nursing Catholic University of CroatiaZagreb 10000Croatia Department of Nursing Bjelovar University of Applied SciencesBjelovar 43000Croatia Department of Surgery University of ZagrebDubrava University HospitalZagreb 10000Croatia Department of Abdominal Surgery University Hospital DubravaZagreb 10000Croatia Doctoral Study of Biomolecular Sciences Josip Juraj Strossmayer University of OsijekOsijek 31000Croatia

BACKGROUND Spontaneous gastric hematoma is an exceedingly rare condition characterized by the accumulation of blood within the gastric wall without any apparent iatrogenic or traumatic *** are the most frequent cause of gastric ***,other causes include amyloidosis,pancreatitis,visceral vas-cular aneurysms,endoscopy complications and *** pathophysiology of spontaneous gastric hematoma is not completely ***,it is postulated that it is caused by disruption of submucosal vessels that leads to dissection of the muscularis layer and formation of false *** rarity of this condition increases the challenge of diagnosis,and there is no standard treatment *** SUMMARY We present the case of a spontaneous gastric hematoma in a 22-year-old *** presented to our emergency department complaining of pain in the left flank area lasting for 2 *** was no history of trauma,antico-agulant medications or endoscopy *** hemoglobin and hematocrit levels were slightly lower than ***-slice computed tomography,ultrasound and endoscopy confirmed a gastric intramural *** recommended conservative treatment because there was no hemodynamic instability nor significant *** patient responded well,and there were no unexpected *** the 3-mo follow-up,the ultrasound exa-mination revealed complete regression of the *** After reviewing the literature and our experience,we recommend that more of these cases should be treated *** tendency to treat these cases with potentially burdensome procedures such as total or subtotal gastrectomy should be significantly reduced.

关键词： Spontaneous Intramural hematoma Stomach Acute abdomen Conservative treatment Case report

Calculation of <i>G</i>Gravity Constant from the Mass and Electron Charge, and Fine Structure Constant

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Journal of Modern Physics 2021年第8期12卷 1172-1181页

作者： valentino Straser Department of Science Environment and Energy Brussels Belgium

This study proposes, from the theoretical point of view, the calculation of the gravitational constant G, made starting from the charge and the electron mass, taking the constant of the Fine Structure into examination. In the empty space, couples of virtual positron electrons dematerialize, giving virtual photon origin. They, at their time, will become electrons, positrons and so on. These transformations are made keeping the board of their “amount of movement” and when they meet the matter, these couples come, reissued depending on the field and on the matter mass. The matter is the change of the trend of their gyromagnetic movement relationship which puts under pressure. In presence of two masses, this gyromagnetic movement relationship is already partially oriented towards the other mass. From here a force is established between these two masses that give as calculated constant equal to 6.678532. This value of G, obtained leaving from the charge and the electron mass, is very near the experimental values estimated in these last decades regard the value of the gravitational constant of G.

关键词： Electron Positron Gravitational Constant String Theory Theory of Everything Fine Structure Constant