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Classifying Big Medical Data through Bootstrap Decision Forest Using Penalizing Attributes

Intelligent Automation & Soft Computing 2023年第6期36卷 3675-3690页

作者： v.gowri v.vijaya Chamundeeswari Department of CSE SRM Institute of Science and TechnologyRamapuram CampusChennaiTamilnaduIndia Department of CSE Saveetha Engineering CollegeChennaiTamilnaduIndia

Decision forest is a well-renowned machine learning technique to address the detection and prediction problems related to clinical ***,the tra-ditional decision forest(DF)algorithms have lower classification accuracy and cannot handle high-dimensional feature space *** this work,we pro-pose a bootstrap decision forest using penalizing attributes(BFPA)algorithm to predict heart disease with higher *** work integrates a significance-based attribute selection(SAS)algorithm with the BFPA classifier to improve the performance of the diagnostic system in identifying cardiac *** pro-posed SAS algorithm is used to determine the correlation among attributes and to select the optimum subset of feature space for learning and testing *** selects the optimal number of learning and testing data points as well as the density of trees in the forest to realize higher prediction accuracy in classifying imbalanced datasets *** effectiveness of the developed classifier is cautiously verified on the real-world database(i.e.,Heart disease dataset from UCI repository)by relating its enactment with many advanced approaches with respect to the accuracy,sensitivity,specificity,precision,and intersection over-union(IoU).The empirical results demonstrate that the intended classification approach outdoes other approaches with superior enactment regarding the accu-racy,precision,sensitivity,specificity,and IoU of 94.7%,99.2%,90.1%,91.1%,and 90.4%,***,we carry out Wilcoxon’s rank-sum test to determine whether our proposed classifier with feature selection method enables a noteworthy enhancement related to other classifiers or *** the experimental results,we can conclude that the integration of SAS and BFPA outperforms other classifiers recently reported in the literature.

关键词： Data classification decision forest feature selection healthcare data heart disease prediction penalizing attributes

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Development and validation of a high throughput UPLC–MS/MS method for simultaneous quantification of esomeprazole,rabeprazole and levosulpiride in human plasma

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Journal of Pharmaceutical Analysis 2016年第3期6卷 190-198页

作者： Raja Haranadha Babu Chunduri gowri Sankar Dannana School of Pharmaceutical Sciences and Technologies Jawaharlal Nehru Technological University Kakinada 533003 Andhra Pradesh India A.U. College of Pharmaceutical Sciences Andhra University Vishakapamam 530003 Andhra Pradesh. India

A high throughput ultra pressure liquid chromatography-mass spectrometry （UPLC-MS/MS） method with good sensitivity and selectivity has been developed and validated for simultaneous quantification of esomeprazole, rabeprazole and levosulpiride in human plasma using lansoprazole as internal standard （IS）. The extraction method based on liquid-liquid extraction technique was used to extract the analytes and IS from of 50 μL of human plasma using methyl tert-butyl ether：ethyl acetate （80：20, v/v）, which offers a high recovery. Chromatographic separation of analytes and IS was achieved on a Hypersil gold C18 column using gradient mobile phase consisting of 2 mM ammonium formate/acetonitrile. The flow rate was set at 0.5 mL/min to elute all the analytes and IS within 1.00 min runtime. Detection of target compounds was performed on a triple quadruple mass spectrometer by multiple reaction monitoring （MRM） mode via positive electrospray ionization （ESI）. Method validation results demonstrated that the developed method has good precision and accuracy over the concentration ranges of 0.1-2000 ng/mL for each analyte. Stability of compounds was established in a battery of stability studies, i.e., bench top, autosampler, dry extract and long-term storage stability as well as freeze-thaw cycles. The validated method has been successfully applied to analyze human plasma samples for application in pharmaco- kinetic studies.

关键词： Esomeprazole Rabeprazole Levosulpiride UPLC-MS/MS Pharmacokinetic studies

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Adaptive Sub-Threshold voltage Level Control for voltage Deviate-Domino Circuits

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Intelligent Automation & Soft Computing 2023年第2期35卷 1767-1781页

作者： C.Arun Prasath C.gowri Shankar Department of Electronics and Communication Engineering Mahendra Engineering CollegeNamakkal637503India Department of Electrical and Electronics Engineering KSR College of EngineeringTiruchengode637215India

Leakage power and propagation delay are two signiﬁcant issues found in sub-micron technology-based Complementary Metal-Oxide-Semiconductor(CMOS)-based very Large-Scale Integration(vLSI)circuit *** Channel Metal Oxide Semiconductor(PMOS)has been replaced by Negative Channel Metal Oxide Semiconductor(NMOS)in recent years,with low dimen-sion-switching changes in order to shape the mirror of voltage *** is used to reduce stacking leakage as well as total *** Logic Cir-cuit is a powerful and versatile digital programmer that gained popularity in recent *** this study regarding Adaptive Sub Threshold voltage Level Control Pro-blem,the researchers intend to solve the contention issues,reduce power dissipa-tion,and increase the noise immunity by proposing Adaptive Sub Threshold voltage Level Control(ASvLC)-based domino *** efﬁciency and effec-tiveness of the domino circuit are demonstrated through simulation *** suggested system makes use of high-speed broad fan-gate circuits,occupies mini-mum space,and consumes meagre amount of *** proposed circuit was validated in Cadence simulation tool at a supply voltage of 1v,frequency of 100 MHz,and an operating temperature of 27°C with 64 input OR *** per the simulation results,the suggested Domino Gate reduced the power dissipa-tion by 17.58 percent and improved the noise immunity by 1.21 times in compar-ison with standard domino logic circuits.

关键词： Domino logic power consumption ﬁgure of merit adaptive sub-threshold voltage level wide fan-in gates

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Optical Field Confinement Enhanced Single ZnO Microrod Uv Photodetector

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Chinese Physics Letters 2017年第7期34卷 283-286页

作者：魏铭徐春祥秦飞飞 Arumugam gowri Manohari 卢俊峰祝秋香 State Key Laboratory of Bioelectronics School of Biological Science and Medical Engineering Southeast University Nanjing 210096

ZnO microrods are synthesized using the vapor phase transport method, and the magnetron sputtering is used to decorate the A1 nanoparticles （NPs） on a single ZnO microrod. The micro-PL and I-v responses are measured before and after the decoration orAl NPs. The FDTD stimulation is also carried out to demonstrate the optical field distribution around the decoration of Al NPs on the surface of a ZnO microrod. Due to an implementation of AI NPs, the ZnO microrod exhibits an improved photoresponse behavior. In addition, AI NPs induced localized surface plasmons （LSPs） as well as improved optical field confinement can be ascribed to an enhancement of ultraviolet （Uv） response. This research provides a method for improving the responsivity of photodetectors.

关键词： ZnO Optical Field Confinement Enhanced Single ZnO Microrod Uv Photodetector Uv

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Large Riedel’s lobe and atrophic left liver in a donor-Accept for transplant or call off?

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World Journal of Transplantation 2020年第5期10卷 129-137页

作者： Yuhki Sakuraoka Rashmi Seth Amanda PCS Boteon Moira Perrin J Isaac gowri Subash Paolo Muiesan Andrea Schlegel The Liver Unit Queen Elizabeth University Hospital BirminghamBirmingham B152THUnited Kingdom Second Department of Surgery Dokkyo Medical UniversityTokyo 321-0293Japan NIHR Liver Biomedical Research Unit University Hospitals BirminghamBirmingham B152THUnited Kingdom

BACKGROUND In context of suboptimal liver utilisation,grafts with various risk factors are under consideration *** example,impaired vascularity with severe arterial calcifications and modified liver shapes are no longer contraindications and their use depends on the centre policy and experience of the surgical *** liver lobes represent a tongue-like liver shape with inferior projection in the right liver *** development modifications were initially described when patients developed a lesion and subsequently presented with *** here present the first case report in the literature,where such livers with anatomical variations were used for *** SUMMARY We describe here two cases of adult human liver transplantation,where we have accepted two donor livers with modified *** technical considerations for transplantation of such livers,found with enlarged right lobes,or Riedel shape,and hypo-trophic left lateral segment are *** recipients experienced immediate liver function and overall good outcomes with a minimum follow up of 1 *** also provide detailed pictures and outcome analysis in combination with a literature *** The utilisation of donor livers with modified shape,such as Riedel’s Lobe appears safe and will increase the donor pool.

关键词： Case report Anatomical variations Riedel’s lobe Liver utilization Liver transplantation

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