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Nano-chromium picolinate and heat stress enhance insulin sensitivity in cross-bred sheep

Animal Nutrition 2023年第2期13卷 173-184页

作者： Alex T.Hung Brian J.Leury Matthew A.Sabin fahri fahri Kristy DiGiacomo tu-fa lien Frank R.Dunshea faculty of Veterinary and Agricultural Sciences The University of MelbourneParkvilleVIC 3010Australia Murdoch Children's Research Institute The University of MelbourneParkvilleVIC 3010Australia Department of Animal Science National Chiayi UniversityChiayiChina faculty of Biological Sciences The University of LeedsLeeds LS29JTUnited Kingdom

This study evaluated the effects of heat stress(HS)and dietary nano chromium picolinate(nCrPic)on metabolic responses of sheep to an intravenous glucose tolerance test(IVGTT),an intravenous insulin tolerance test(ITT)and an intramuscular adrenocorticotropin hormone(ACTH)challenge in ***-six sheep housed in metabolic cages were randomly allocated within 3 dietary groups(0,400 and 800 mg/kg supplemental nCrPic)to either thermoneutral(22℃)or cyclic HS(22 to 40℃)conditions for 3 *** plasma glucose tended to be increased during HS(P=0.052)and decreased by dietary nCrPic(P=0.013)while plasma non-esterified fatty acid concentrations were decreased(P=0.010)by ***-etary nCrPic reduced the plasma glucose area under the curve(P=0.012)while there were no significant effects of HS on plasma glucose area under the curve in response to the *** plasma insulin response over the first 60 min after the IVGTT was decreased by HS(P=0.013)and dietary nCrPic(P=0.022)with the effects being *** response to the ITT plasma glucose reached a nadir sooner(P=0.005)in sheep exposed to HS,although there was no effect on the depth of the *** nCrPic decreased(P=0.007)the plasma glucose nadir after *** the duration of the ITT plasma insulin concentrations were lower in sheep exposed to HS(P=0.013)whereas there was no significant effect of supplemental *** was no effect of either HS or nCrPic on cortisol response to *** nCrPic supple-mentation decreased(P=0.013)mitogen-activated protein kinase-8(JNK)and increased(P=0.050)carnitine palmitoyltransferase 1B(CPT1B)mRNA expression in skeletal *** of this experiment demonstrated that animals under HS and supplemented with nCrPic had greater insulin sensitivity.

关键词： Chromium picolinate Sheep Heat stress Insulin sensitivity

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Dietary nano chromium picolinate can ameliorate some of the impacts of heat stress in cross-bred sheep

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Animal Nutrition 2021年第1期7卷 198-205页

作者： Alex T.Hung Brian J.Leury Matthew A.Sabin fahri fahri Kristy DiGiacomo tu-fa lien Frank R.Dunshea faculty of Veterinary and Agricultural Sciences The University of MelbourneParkvilleVIC3010Australia Murdoch Children's Research Institute The University of MelbourneParkvilleVIC3010Australia Department of Animal Science National Chiayi UniversityChina faculty of Biological Sciences The University of LeedsLeeds LS29JTUnited Kingdom

Two studies were conducted to evaluate the effect of nano chromium picolinate(nCrPic)during heat stress(HS)in *** the initial study,36 Merino×Poll cross-bred sheep were individually penned and allocated to 3 dietary treatments(0,400 and 800μg/kg nCrPic)for 8 *** composition was determined at the beginning and end of the experiment using dual energy X-ray *** sheep remained in their dietary groups but were then placed in metabolic cages and randomly allocated within the dietary group to differing ambient temperature regimes,i.e.,thermo-neutral(TN)(n=18)and HS(n=18),for 3 *** nCrPic had no effect on growth performance and body composition during the initial study conducted under TN *** stress decreased average daily feed intake(ADFI)(P=0.002)whereas sheep under HS had reduced average daily gain(ADG)and indeed lost weight(Pture(Pture was lower in sheep fed nCrPic(P=0.050),particularly under peak HS conditions during the afternoon as indicated by the interactions between dietary nCrPic and time of day(P<0.001)and dietary nCrPic,thermal treat-ment and time of day(P=0.010).Similarly,respiration rate was lower in sheep fed nCrPic under peak HS conditions during the afternoon as indicated by the interactions between dietary nCrPic and thermal treatment(P<0.001)and dietary nCrPic and time of day(P=0.030).In conclusion,dietary nCrPic can partially ameliorate the negative effects of HS as indicated by the maintenance of ADFI and decreased physiological responses,such as elevatio

关键词： Chromium picolinate Sheep Heat stress Nanotechnology Physiology

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定量核磁共振磷谱同时测定浓维磷糖浆中甘油磷酸钠和磷酸的含量

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分析化学 2024年第7期52卷 1020-1027页

作者：屠相土李俊雷虹徐玲萍曾茂法台州市食品药品检验研究院

建立了定量核磁共振磷谱法(31P-q NMR)同时测定浓维磷糖浆中α-甘油磷酸钠、β-甘油磷酸钠和磷酸含量的方法。考察了q NMR实验条件对测定结果的影响，选择六甲基磷酰三胺为内标、20%重水溶液（V/V）为溶剂，选择zgig脉冲序列、延迟时间3... 详细信息

建立了定量核磁共振磷谱法(31P-q NMR)同时测定浓维磷糖浆中α-甘油磷酸钠、β-甘油磷酸钠和磷酸含量的方法。考察了q NMR实验条件对测定结果的影响，选择六甲基磷酰三胺为内标、20%重水溶液（V/V）为溶剂，选择zgig脉冲序列、延迟时间30 s、扫描次数64次为实验条件，进行采样测试获取31P-q NMR谱，其中，六甲基磷酰三胺、α-甘油磷酸钠、β-甘油磷酸钠和磷酸的定量共振峰分别为δ 29.80、δ 0.69、δ 0.17和δ 0.03（供试品溶液p H≈4.8）。结果表明，31P-q NMR法测定α-甘油磷酸钠、β-甘油磷酸钠和磷酸的检出限分别为23.58、23.58和11.61μg/m L，定量限分别为78.60、78.60和38.70μg/m L，线性相关系数（R）均大于0.999，精密度小于0.6%，平均回收率为99.8%～103.2%，相对标准偏差（RSD）为0.41%～1.98%。本研究建立的31P-q NMR方法测定结果准确，稳定可靠。采用本方法测定了7批次不同厂家的浓维磷糖浆样品，其中，总磷量检测结果与比色法一致；甘油磷酸钠含量（α型与β型之和）偏低，约为标示量的82%；磷酸含量偏高。本方法操作简单、专属性强，适合作为浓维磷糖浆质量控制的方法。

关键词：定量核磁共振磷谱法浓维磷糖浆甘油磷酸钠磷酸

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NIR-IIb-triggered photodynamic therapy combined with chemotherapy platform based on rare-earth-doped nanoparticles

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Rare Metals 2024年第7期43卷 3220-3231页

作者： Zhuo tu Yong Wan Juan Ge Chen-Chen Li Tao Liang Zhen Li Chemistry and Chemical Engineering Hubei UniversityWuhan 430062China

Photodynamic therapy(PDT),with high spatiotemporal selectivity,minimal side effects and less drug resistance,has emerged as a promising approach for the treatment of ***,inadequate penetration depth and poor efficacy seriously restrict its practical *** address these challenges,we developed a combined therapy platform(RENP@C/D-fa)based on rare-earth-doped nanoparticles(RENPs)with a structure of NaErF_(4):Tm(0.5%)@NaYF_(4),on which photosensitizer Ce6(chlorin e6)and chemo-therapeutic drug(DOX)(doxorubicin)were loaded by encapsulating with an amphiphilic polymer distearoyl phosphatidylethanolamine-polyethylene glycol-folic acid(DSPE-PEG-fa).RENPs with NaErF_(4) as the matrix possess multiple excitation/emission peaks,enabling activation of PDT under near-infrared-Ⅱb(NIR-Ⅱb,1500-1700 nm)excitation and luminescence imaging in NIR-Ⅱb region by absorbing 808 nm near-infrared ***,DOX can be selectively released in the acidic microenvironment of *** from the tumor targeting capability of folic acid,this platform can successfully ablate tumor cells and inhibit tumor growth by combining PDT and *** innovative approach holds great promise as a powerful tool for cancer treatment,showing the potential to revolutionize PDT.

关键词： Photodynamic therapy Rare-earth-doped nanoparticles NIR-IIb Chemotherapy Combined therapy

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高校优秀运动员培养的演化博弈分析

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广州体育学院学报 2024年第2期44卷 94-100页

作者：陈土发东莞城市学院通识教育学院广东东莞523419

高校作为运动员培养的重要基地之一,对优秀运动员的培养与发掘有着重要作用。本研究根据双方的行为逻辑构建演化博弈模型,模拟不同时间序列下的情景,真实动态地分析探究高校运动员与高校教育体系投入(认真)行为的关联影响程度,深入研究... 详细信息

高校作为运动员培养的重要基地之一,对优秀运动员的培养与发掘有着重要作用。本研究根据双方的行为逻辑构建演化博弈模型,模拟不同时间序列下的情景,真实动态地分析探究高校运动员与高校教育体系投入(认真)行为的关联影响程度,深入研究寻找双方行为概率的关键性因素。研究表明:高校优秀运动员培养与高校方投入成本、运动员训练投入程度、社会声誉支持等参数有直接关系。结合Matlab仿真分析,高校竞技体育产业化道路、竞赛体制改革等方式有助于优化高校优秀运动员培养机制。

关键词：优秀运动员体制改革模式优化演化博弈

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Application of prostate resectoscope in the treatment of massive rectal bleeding after transrectal prostate puncture

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World Journal of Clinical Cases 2024年第18期12卷 3438-3443页

作者： Hong-Mei Li fa-Ying Yang Song tu Peng Yan Jun Qian Jia-Xi Yao Department of Urology Hexi University Affiliated Zhangye People’s HospitalHexi UniversityZhangye 734000Gansu ProvinceChina Department of General Surgery II Hexi UniversityZhangye 734000Gansu ProvinceChina

BACKGROUND Ultrasound-guided prostate biopsy is a reliable diagnostic procedure for prostate cancer diagnosis with minimal procedure-related ***,complications,such as massive rectal bleeding may occur after the *** hypothesized that using a transrectal resectoscope could help treat massive rectal bleeding after transrectal prostate *** To identify a simple and effective treatment for massive rectal bleeding after transrectal prostate *** Patients requiring treatment for massive rectal bleeding after transrectal prostate punctures were included.A SIMAI resectoscope was inserted through the *** electrocoagulation was performed for superficial bleeding *** of the rectal mucosa or surface muscle layer was removed to expose deep bleeding points,followed by *** electric cutting ring was used to compress and stop the bleeding for jet-like points before *** fluid color in the drainage tube was monitored postoperatively for continuous *** Eight patients were included from 2012 to *** of the patients with massive rectal bleeding after the transrectal prostate punctures improved with conventional conservative and blood transfusion *** patients had an inferior artery embolism,and digital subtraction angiography was *** patients received emergency transanal prostate resection,which immediately stopped the *** days after the procedure,the patients had recovered and were *** Using a transanal prostate resection instrument is a simple,safe,and effective method for treating massive rectal bleeding after transrectal prostate punctures.

关键词： Electrocoagulation Hemostasis Transanal prostate resection instrumentation Prostate puncture

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日粮添加适量的鱼油和油菜籽油可生产更利于人体健康的猪肉

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猪业科学 2017年第9期34卷 24-26页

作者：伍佰鑫李昊帮孙鏖张翠永 Jyun-Ru Yang tu-fa lien 湖南省畜牧兽医研究所湖南长沙410131

60头三元杂交猪(长白猪×约克夏×杜洛克),平均体重(66.5±5.2)kg,分成5个日粮处理组,每组4个重复;即(1)猪油;(2)豆油;(3)含有亚麻籽的商业鱼产品;(4)油菜籽油;(5)50%的鱼油和50%的油菜籽油。试验期为90 d,日粮分为生长阶段(体重80 kg以... 详细信息

60头三元杂交猪(长白猪×约克夏×杜洛克),平均体重(66.5±5.2)kg,分成5个日粮处理组,每组4个重复;即(1)猪油;(2)豆油;(3)含有亚麻籽的商业鱼产品;(4)油菜籽油;(5)50%的鱼油和50%的油菜籽油。试验期为90 d,日粮分为生长阶段(体重80 kg以下)和育肥阶段。在第60天采集血样,在试验结束时每组宰杀8头猪,取肌肉和脂肪样品。结果表明,不同油脂的日粮不会影响育肥猪的生长性能、胴体特征、猪肉储藏后的抗氧化特性和肉质,但会影响猪体脂肪酸组成。随着豆油和油菜籽油的追加,饱和脂肪酸减少、多元不饱和脂肪酸增加;含有亚麻籽鱼产品、油菜籽油、50%鱼油和50%油菜籽油的日粮可以减少猪肉中n-6脂肪酸与n-3脂肪酸的比率,随着追加时间的延长,效果相当明显;含有50%鱼油和50%油菜籽油的日粮可减少血浆胆固醇、低密度脂蛋白、低密度脂蛋白-胆固醇(动脉和心脏的不利因子),增加高密度脂蛋白和高密度脂蛋白-胆固醇的含量(动脉和心脏的有利因子)。因此,日粮添加适量的鱼油和油菜籽油,可为消费者生产出更为健康的猪肉。

关键词：猪日粮油脂 n-6脂肪酸 n-3脂肪酸

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新文科背景下大学英语教师课程思政素养能力调研与策略

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红河学院学报 2024年第2期22卷 43-48页

作者：周发忠涂慧娟江西理工大学基础课教学部江西南昌330013 江西财经大学外国语学院江西南昌330013

新文科坚持立德树人,倡导跨学科跨专业创新教学;教师是课程思政建设关键。研究以跨学科政治素养认知、跨学科专业素养认知、跨专业人文素养认知和跨学科信息素养认知为维度,通过对江西地方高校大学英语教师课程思政素养能力问卷调研,结... 详细信息

新文科坚持立德树人,倡导跨学科跨专业创新教学;教师是课程思政建设关键。研究以跨学科政治素养认知、跨学科专业素养认知、跨专业人文素养认知和跨学科信息素养认知为维度,通过对江西地方高校大学英语教师课程思政素养能力问卷调研,结果显示四个维度均受到教师性别、教龄、职称等个人因素不同程度影响。为此,研究提出组建“亲他—亲我”共同体、营造跨学科课程思政教科研氛围和搭设多样化信息技术学习平台的建议以作问题策略,供新文科背景下大学英语教师队伍建设与发展以支撑参考用。

关键词：新文科大学英语教师课程思政素养

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基于RFID温度标签的变电站装配式线缆槽盒温度监控方法

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自动化技术与应用 2024年第8期43卷 68-72页

作者：徐伟明屠锋李斌吴正清王法嘉兴恒创电力设计研究院有限公司浙江嘉兴314000 国网浙江省电力有限公司浙江杭州310000 国网嘉兴供电公司浙江嘉兴314000

由于红外测温仪和温度传感器在采集温度数据时会出现偏差,且监控方法能耗较高。对此,提出基于RFID温度标签的变电站装配式线缆槽盒温度监控方法。设计一种RFID温度标签,采集变电站装配式线缆槽盒温度数据,并实施数据清理以及数据变换预... 详细信息

由于红外测温仪和温度传感器在采集温度数据时会出现偏差,且监控方法能耗较高。对此,提出基于RFID温度标签的变电站装配式线缆槽盒温度监控方法。设计一种RFID温度标签,采集变电站装配式线缆槽盒温度数据,并实施数据清理以及数据变换预处理。结合关联维提取预处理好的温度数据特征。通过计算异常指数,判断变电站装配式线缆槽盒温度异常状态。结果表明:与基于红外测温仪的监控方法和基于温度传感器的监控方法相比,所研究的方法采集数据与真实数据的拟合度更高,达到0.9852,说明采集数据更为准确,该方法更能维持长时间的监控工作。

关键词： RFID温度标签变电站装配式线缆槽盒特征提取温度监控方法

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Designing a location update strategy for free-moving and network-constrained objects with varying velocity

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Journal of Zhejiang University-Science C(Computers and Electronics) 2014年第8期15卷 675-686页

作者： Yuan-Ko HUANG lien-fa LIN Department of Information Communication Kao-Yuan University

Spatio-temporal databases aim at appropriately managing moving objects so as to support various types of queries. While much research has been conducted on developing query processing techniques, less effort has been made to address the issue of when and how to update location information of moving objects. Previous work shifts the workload of processing updates to each object which usually has limited CPU and battery capacities. This results in a tremendous processing overhead for each moving object. In this paper, we focus on designing efficient update strategies for two important types of moving objects, free-moving objects(FMOs) and network-constrained objects(NCOs), which are classified based on object movement models. For FMOs, we develop a novel update strategy, namely the FMO update strategy(FMOUS), to explicitly indicate a time point at which the object needs to update location information. As each object knows in advance when to update(meaning that it does not have to continuously check), the processing overhead can be greatly reduced. In addition, the FMO update procedure(FMOUP) is designed to efficiently process the updates issued from moving objects. Similarly, for NCOs, we propose the NCO update strategy(NCOUS) and the NCO update procedure(NCOUP) to inform each object when and how to update location information. Extensive experiments are conducted to demonstrate the effectiveness and efficiency of the proposed update strategies.

关键词： Spatio-temporal databases Moving objects Free-moving objects Network-constrained objects

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