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与早产儿视网膜病变瘢痕期相关的闭角型青光眼的高分辨超声检查

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世界核心医学期刊文摘(眼科学分册) 2006年第1期 59-59页

作者： suzuki A. Kondo N. Terasaki H. 邢咏新 Department of Ophthalmology NagoyaUniversitySchool of Medicine 65 Tsuruma-cho Showa-ku Nagoya 466-8550 Japan

Background: Angle-closure glaucoma in children at the cicatricial stage of retinopathy of prematurity (ROP) has been thought to be caused by the anterior displacement of the lensiris diaphragmresulting from contraction of a retrolental fibrous membrane. Other possible mechanisms include pupillary block and ciliary block. Cases: Three patients (three eyes) at the cicatricial stage of ROP with angle-closure glaucoma were examined by high-resolution ultrasonography before and after peripheral iridectomy. Observations: High-resolution ultrasonography preoperatively showed that the angle was closed. A retrolental fibrous membrane was attached behind the lens. After the iridectomy, ultrasonography showed an open angle, and the intraocular pressure was normal. Conclusions: The angle closure in our three patients was caused mainly by a pupillary block and could be treated by peripheral iridectomy.

关键词：闭角型青光眼高分辨超声视网膜早产儿瘢痕病变

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明日风尚 2007年第3期 59-59页

作者：吴靖李雁刚 suzuki 一本 Eric Lu

停驻"脚下"天色微暗,有些清冷的空气,沿着鼓楼外大街走着,路过几家闪着红色小彩灯的小酒馆,从铃铛胡同往北,看着在路边嬉戏玩耍的孩子,一抬头,就到了鼓楼。再顺着墙角儿一拐,突然被一片温暖的灯光包围。这,就是"脚下咖啡"了。跟其他拥... 详细信息

停驻"脚下"天色微暗,有些清冷的空气,沿着鼓楼外大街走着,路过几家闪着红色小彩灯的小酒馆,从铃铛胡同往北,看着在路边嬉戏玩耍的孩子,一抬头,就到了鼓楼。再顺着墙角儿一拐,突然被一片温暖的灯光包围。这,就是"脚下咖啡"了。跟其他拥挤在后海前沿的咖啡馆不一样,"脚下咖啡"选择了鼓楼旁这条僻静的小巷——钟楼湾。小小的门面,安静地对着鼓楼前的一小片草地。如果不是遛弯。

关键词：色微后海游来游去举办地点冷调奥地利人空间延伸娱乐区歇歇脚私密性

Cyclophilin A在血管平滑肌细胞中经囊状途径分泌

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中国动脉硬化杂志 2006年第5期14卷 394-394页

作者： suzuki J Meoli DF Matoba T Berk BC 谢闵

活性氧通过促进血管平滑肌细胞生长来部分地促使动脉粥样硬化发生。我们以前的研究证明,cyclophi1in A(CyPA)是一种分泌型氧化应激诱导因子,它促进炎症发生、血管平滑肌细胞生长和内皮细胞凋亡。然而,调节CyPA分泌的机制还不清楚。在这... 详细信息

活性氧通过促进血管平滑肌细胞生长来部分地促使动脉粥样硬化发生。我们以前的研究证明,cyclophi1in A(CyPA)是一种分泌型氧化应激诱导因子,它促进炎症发生、血管平滑肌细胞生长和内皮细胞凋亡。然而,调节CyPA分泌的机制还不清楚。在这个研究中,假设由活性氧诱导的CyPA自血管平滑肌细胞的分泌需要一个囊泡转运、对接和与质膜融合的高度调节过程。制备条件培养基和质膜片,[第一段]

关键词：血管平滑肌细胞生长 Cyclophilin 分泌型囊状中经动脉粥样硬化内皮细胞凋亡 CyPA 条件培养基诱导因子

Anti-Melanogenesis Activity of Supercritical Carbon Dioxide Extract from Perilla frutescens Seeds

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在不影响人足细胞(前)肾素受体信号下,阿利吉仑能抑制细胞内血管紧张素Ⅱ水平

Advances in Biological Chemistry（生物化学进展） 2023年第1期

作者： Satoshi suzuki Hitomi Fujisawa Junpei Abe Ken-ichi Kimura

来源：博看期刊评论

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中华高血压杂志 2010年第7期18卷 698-698页

作者： Sakoda M Ichihara A Kurauchi-Mito A Narita T Kinou-chi K Murohashi-Bokuda K Saleem MA Nishiyama A suzuki F Itoh H 黄晓斌

直接肾素抑制剂能使已接受血管紧张素Ⅱ1型受体拮抗剂治疗的2型糖尿病患者尿白蛋白排出量减少,这表明阿利吉仑也许有区别于传统肾素血管紧张素系统(renin-angiotensin system,RAS)拮抗剂的作用。最近发现了(前)肾素结合受体[(pro)reninr... 详细信息

直接肾素抑制剂能使已接受血管紧张素Ⅱ1型受体拮抗剂治疗的2型糖尿病患者尿白蛋白排出量减少,这表明阿利吉仑也许有区别于传统肾素血管紧张素系统(renin-angiotensin system,RAS)拮抗剂的作用。最近发现了(前)肾素结合受体[(pro)reninreceptor,(P)RR],可以激活两条通路:血管紧张素肽生成和激活受体依赖的细胞外信号相关蛋白激酶(extracellular signal-related protein kinase,ERK)。由于(P)RR存在于人足细胞并且是肾小球滤过屏障的一个重要组成部分,所以假设阿利吉仑可以影响人足细胞(P)RR诱导的两条通路。[第一段]

关键词：肾素血管紧张素系统足细胞肾素抑制剂咪达普利拉受体拮抗剂坎地沙坦水平细胞抑制细胞治疗后磷酸化

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螺内酯对腹膜透析患者的长期效应

中华肾病研究电子杂志 2014年第3期3卷 14-14页

作者： Ito Y Mizuno M suzuki Y 王建中解放军总医院解放军肾脏病研究所

经血液透析或腹膜透析治疗的终末期肾脏病（end—stagerenalfailure，ESRD）患者，常常合并左心室肥厚（1eftventficularhypertrophy，LVH）、纤维化和毛细血管减少。导致CKD（chronickidneydisease，CKD）患者发生心肌病和左心室衰竭... 详细信息

经血液透析或腹膜透析治疗的终末期肾脏病（end—stagerenalfailure，ESRD）患者，常常合并左心室肥厚（1eftventficularhypertrophy，LVH）、纤维化和毛细血管减少。导致CKD（chronickidneydisease，CKD）患者发生心肌病和左心室衰竭的主要机制有三个：压力超负荷、容量超负荷、以及CKD相关的非血液动力学因素。LVH的晚期事件包括泵衰竭和心律失常性猝死。因此，需要一种新的治疗模式来预防和逆转ESRD患者的LVH和心肌纤维化。据报道，盐皮质激素受体拮抗剂能够改善慢性心力衰竭和心肌梗塞后心力衰竭患者的生存期，并能减少左心室的质量。然而，有关盐皮质激素受体阻断剂对透析患者的作用报道很少，样本也小，尚不足以得出相关结论。

关键词：腹膜透析治疗透析患者长期效应螺内酯血液动力学因素左心室肥厚心肌纤维化盐皮质激素

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伴睑板腺炎的疱性角膜炎青年患者

世界核心医学期刊文摘（眼科学分册） 2005年第12期1卷 10-10页

作者： suzuki T Mitsuishi Y Sano Y 陈立军 Department of Ophthalmology Kyoto Prefectural University of Medicine Kajii-cho Kamigyo-ku Kyoto City 602- 0841 JapanDr

PURPOSE: To describe the unique clinical features of phlyctenular keratitis, including the association with meibomitis, in young patients. DESIGN: Observational case series. METHODS: The study population consisted of 23 Japanese patients aged under 35 years with phlyctenular keratitis. We examined their clinical history, signs and symptoms, human leukocyte antigen (HLA), bacterial cultures of meibum, and the efficacy of antibiotics. The minimal diagnostic criteria included corneal nodules consisting of cellular infiltrates and superficial neovascularization. RESULTS: Of the 23 patients, 20 (87% )- were women, and 13 (56.5% ) had a history of chalazia. In all cases, the lesions and the severity of corneal nodules and neovascularization corresponded well with the location and the severity of meibomitis. The frequency of HLA- A26 and HLA- B35 was significantly increased in our patients (P=.003 and .016, respectively). Propionibacterium acnes in bacterial cultures of pure meibum in 12 of the 20 patients (60% ) was statistically more highly positive than those in four of the 17 age-matched normal control subjects (23.5% ; P=.028). CONCLUSION: The characteristics of phlyctenular keratitis in our cases include significantly higher prevalence in female patients, severity variation of ocular surface manifestation corresponding to meibomitis, specific HLA association, and possible P. acnes involvement.

关键词：睑板腺炎小疱棒状杆菌霰粒肿人白细胞抗原研究人群严重度病例研究观察性

源于非色素睫状上皮伴发视盘新生血管和黄斑囊样水肿的腺瘤

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世界核心医学期刊文摘（眼科学分册） 2005年第6期1卷 12-12页

作者： suzuki J. Goto H. UsuiM. 程燕

To report a case of adenoma of the nonpigmented ciliary epithelium concomitant with marked neovascularization of the optic disk and cystoid macular edema (CME). Observational case report. A 34- year-old woman presented with a nonpigmented, vascularized tumor behind the iris and neovascularization of the optic disk (NVD). Visual acuity decreased gradually as a result of the development ofCME. Iridocyclectomy to excise the tumorwas performed 8months after initial examination. Histopathologic study revealed an adenoma arising from the NPCE. The levels of vascular endothelial growth factor were signifi-cantly elevated in both aqueous and vitreous humor obtained at surgery. The NVD and CME regressed after surgery, and the postoperative visual acuity improved to 20/40. NVD and CME may develop secondary to adenoma of the nonpigmented ciliary epithelium. Increased levels of vascular endothelial growth factor in intraocular fluids may play a role in NVD and CME development.

关键词：黄斑囊样水肿于非术后视力眼内液病理学研究观察性中起

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输卵管腺癌引起的伴癌小脑退行性变

世界核心医学期刊文摘（妇产科学分册） 2006年第3期2卷 46-46页

作者： Tanaka Y. suzuki N. 杨晓梅 Department of Obstetrics and Gynecology School of Medicine Keio University 35 Shinanomachi Shinjuku-ku Tokyo 160-8582 Japan

Background. Paraneoplastic cerebellar degeneration (PCD) is rarely caused by fallopian tube adenocarcinoma. Case. We present a patient with PCD and fallopian tube cancer. Anti-Yo antibody, one of an anti-neuronal antibody, was positive in serum and cerebrospinal fluid. She was also positive for HLA A24, which is common in patients with PCD. Radical surgery did not significantly ameliorate her neurological impairment, although the dysarthria improved slightly. Conclusion. This case highlights the importance of detecting the underlying malignancy in patients with subacute neurological impairment and shows that fallopian tube cancer can potentially cause PCD.

关键词：输卵管癌退行性变抗神经元抗体发音困难神经损害根治手术