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20-Hydroxyecdysone from Dacrycarpus imbricatus bark inhibits the proliferation of acute myeloid leukemia cells

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Asian Pacific Journal of Tropical Medicine 2017年第2期10卷 151-153页

作者： trinh Thi Thuy Nguyen Thanh Tam Nguyen Thi Hoang Anh Dang Viet Hau Dinh Thi Phong Le Quoc Thang Sabrina Adorisio Tran van Sung Domenico V Delfino Institute of Chemistry Vietnam Academy of Science and Technology Vietnam National Museum of Nature Vietnam Academy of Science and Technology Hue University’s College of Educations Section of Pharmacology Department of MedicineUniversity of Perugia

Objective:To investigate the anti-proliferative effects of 20-hydroxyecdysone isolated from the bark of Dacrycarpus imbricatus(Blume) de ***:Column chromatography was used for isolation of compounds from plant *** structure of the isolated compound was identified by mass spectrometry and nuclear magnetic resonance techniques,including HSQC,HMBC,NOE-difference *** isolated compound was tested for its anti-proliferative activity in acute myeloid leukemia(AML) and OCI-AML ***:Compound 1 was isolated from the ethyl acetate fraction of Dacrycarpus imbricatus barks by column *** chemical structure was identified as 20-hydroxyecdysone(20HE),a cholestane-type ecdysteroid,by a combination of mass spectrometry and nuclear magnetic resonance spectrometric *** goal was to test the anti-proliferative activity of 20 HE using the OCI-AML cell line.20 HE significantly decreased OCI cell number at a concentration of 1 mg/mL,whereas lower concentrations were ***,this decrease was due to partial blockage of the G_1/S phase of the cell cycle,with a reduction of cells in the G_2M phase,not due to increased ***:This indicates that 20 HE significantly decreases the number of cells in the G_1/S phase of the cell cycle in human AML *** is the first time that the anti-proliferative activity of 20 HE against a human tumor cell line has been reported.

关键词： Dacrycarpus imbricatus Ecdysteroid 20-hydroxyecdysone Proliferation Acute myeloid leukemia

Positron Annihilation in Perfect and Defective TiO<sub>2</sub>Rutile Crystal with Single Particle Wave Function: Slater Type Orbital and Modified Jastrow Functions

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World Journal of Nuclear Science and Technology 2014年第1期4卷 33-39页

作者： trinh Hoa Lang Chau van Tao Kieu Tien Dung Le Hoang Chien Faculty of Physics and Engineering Physics University of Science Ho Chi Minh City Vietnam Swinburne University of Technology Melbourne Australia

Positron annihilation in TiO2 rutile crystal is studied by an assumption that a positron binds with valance electrons of a titanium dioxide to form a pseudo TiO2-positron molecule before it annihilates with these electrons. The orbital modification consisting of explicit electron-positron and electron-electron correlation in each electronic orbital is used for the electrons and positron wave functions. By these wave functions, the calculation results of the positron lifetimes in unmitigated and defective TiO2 crystals are about 170 ps, 266 ps and 243 ps, respectively. These results are in good agreement with experimental data of the positron lifetimes in vacancies of TiO2 from 180 ps to 300 ps.

关键词： Positron Annihilation Jastrow Lifetime VQMC TiO2

Adaptability Zoning for Salty-Tolerant Rice Varieties in Soc Trang Prefecture by Using GIS and Remote Sensing

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Journal of Geological Resource and Engineering 2016年第3期4卷 142-150页

作者： Tran Thanh Dan Tran Thi Ngoc trinh Vo Quang Minh Huynh Ngoc van Department of Land Resources College of the Environment and Natural Resources Can Tho University Viet Nam Department of Science and Technology Graduate School of Engineering Nagasaki University Japan Center of Seed and Plant Soc Trang province Viet Nam

Soc Trang is one of coastal provinces in which rice land is relatively low and therefore under annual threat of saline intrusion and other climatic variabilities. It raises an urgent need to identify various rice varieties which are short-duration, highly adaptive to salinity penetration, floods and aluminium poisonous matters, as well as high productivity and quality. The research applies the GIS （Geo-Information System） and RS （Remote Sensing） techniques to accurately evaluate the adaptability of different salinity-tolerant rice varieties. We have used information from FAO （The Food and Agriculture Organization）, Maplnfo and ArcGIS to map different components separately that are overlapped and mixed together to build different maps indicating the adaptability of different rice varieties to salinity in different locations in Soc Trang. We have also identified various factors affecting the productivity of these rice varieties. Then, several salinity-resistent rice varieties have been piloted in different areas to figure out which varieties are most suitable for specific regions.

关键词： Adaptability salty-tolerant rice climate change remote sensing GIS.

Design and Manufacture an Elastic Neutron Scattering Spectrometer at the Dalat Nuclear Reactor

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Journal of Analytical Sciences, Methods and Instrumentation 2021年第3期11卷 23-28页

作者： Dang Hong Ngoc Quy Pham Ngoc Son Phan Bao Quoc Hieu trinh van Cuong Nuclear Research Institute Dalat Lam Dong Vietnam

The objective of this study is to design an elastic neutron scattering system according to the angle with a sample using thermal neutron beam at the Dalat Nuclear Reactor (DNR). The system is used for research and training in the field of material structure analysis by neutron scattering and diffraction techniques. It is designed on the basis of inheriting the neutron measurement spectrometer systems at the DNR and the scattered neutron measurement systems in the world. The measuring system, which was installed at the horizontal channel 4 of the DNR, consists of 5-helium-3 detectors and a fully electronic system to record the scatter counts and a mechanical system with the possibility of rotating at 15˚-75˚ angles. The constructed system is tested for evaluation of the accuracy, stability and reliability of the mechanical and electronic systems of moving detectors by angles.

关键词： Neutron Scattering Small-Angle Neutron Scattering (SANS) Elastic Neu-tron Cross Section

In vivo anticancer activity of maesopsin 4—O— β—glucoside isolated from leaves of Artocarpus tonkinensis *** Gagnep

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Asian Pacific Journal of Tropical Medicine 2016年第4期9卷 343-348页

作者： trinh Thi Thuy Dao Duc Thien Tran Quang Hung Nguyen Thanh Tam Nguyen Thi Hoang Anh Nguyen Thi Nga Nguyen Thi Cuc Le Phuong Mai Tran van Sung Domenico V.Delfino Do Thi Thao Institute of Chemistry.Vietnam Academy of Science and Technology Institute of Biotechnology Vietnam Academy of Science and Technology National Research Council Canada Measurement Science and Standards1200 Montreal RoadBuilding M-12.Ottatca.Ontario KIA OR6 Department of Medicine University of PerugiaPiazzale Gambuli.S.Andrea delle Fratte

Objective:To investigate the antitumor effect of maesopsin 4-O-β-glucoside(TAT2) isolated from the leaves of Artocarpus tonkinensis(***) *** ***:The antitumor activity of TAT2 was evaluated in Lewis lung carcinoma(LLC) tumor-bearing ***/c mice had tumors induced by implantation with 2× 10~6 LLC cells into the subcutaneous right posterior ***-bearing mice were treated orally with a range of doses of TAT2 and a standard drug,*** were observed for tumor growth and mortality *** was collected to determine hematological and biochemical *** TAT2 was isolated from an ethanolic extract of *** *** structure was determined by MS and NMR spectroscopy,and identified as *** compound did not show acute toxicity at the highest dose tested(2 OIK) mg/kg body weight).TAT2 exhibited antitumor activity by decreasing tumor growth,increasing the survival rale,and ameliorating some hematological and biochemical parameters at doses of 100 and 200 mg/kg body weight(P<0.05).Conclusions:These results indicate that TAT2 possesses clear antitumor *** to its bioavailability and low toxicity,and the fact that it could be isolated in a large scale from *** leaves,the compound shows promise as a potential anticancer drug.

关键词： Artocarpus tonkinensis BALB/c Hematological parameters Lewis lung carcinoma Maesopsin 4-0-β-glucoside

Assessment of Groundwater Recharge from Rainfall in the Plain of Cai Phan Rang, Vietnam

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Journal of Environmental Science and Engineering(A) 2014年第3期3卷 141-149页

作者： Chau Tran Vinh Nguyen Minh Khuyen Nguyen Hong Hieu Doan van Long Nguyen Tien Bach trinh ThiThu van Department of Water Resources Management Ministry of Natural Resources and Environment Hanoi 100000 Vietnam

This paper presents the quantitative assessment results of rainwater supply to groundwater in Cai Phan Rang River basin, Ninh Thuan province, Vietnam. In order to obtain the results, the authors developed two experimental areas with 10 wells which were monitored in one year to assess the infiltration supply of rainwater to groundwater. The results of this research assessed the amount of rainwater infiltrates into groundwater varies from 307.16-314.98 tam·year^-1, average is 311 mm·year^-1. The findings are significant in terms of science which identify sources of groundwater storage from the infiltration supply of rainwater. The findings are also practical in suggesting measures to reserve groundwater for the purpose of socio-economic development in the study area.

关键词： Groundwater recharge rainwater infiltration rainwater infiltration into groundwater.

Genesis and Quality of Groundwater in the Southeastern Region of Southern Vietnam

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Journal of Environmental Science and Engineering(A) 2017年第6期6卷 277-292页

作者： Chau Tran Vinh Tran Hong Thai Doan van Canh Dang Due Nhan Nguyen Cao Huan Nguyen van Nghia Nguyen Hong Hieu trinh Thi Thu van Department of Water Resources Management Ministry of Natural Resources and Environment Hanoi 100000 Vietnam National Meteorological and Hydrological Center Hanoi 100000 Viemam Hydrogeology Assoeiation of Vietnam Hanoi 100000 Vietnam Department of Geology Hanoi University of Natural Sciences Hanoi 100000 Vietnam

The origin and quality of groundwater in the Southeastern region （belongs to Southern Plain） were identified by using isotopic techniques and geochemical analysis. Groundwater samples were collected from 7 aquifers： the Holocene, upper Pleistocene, middle Pleistocene, lower Pleistocene, upper Pliocene, middle Pliocene and Miocene aquifers. The water isotopic compositions （82H and 8180） were determined to elucidate the origin and the interaction between surface water and groundwater studies. Transit time （age） of the groundwater samples was determined to explain the direction of groundwater flow. The dating techniques included 3H and ^14C isotopes measurement, followed by a correction for the initial ^14C-activity by the ^13C-composition （^13C） in TDIC （Total Dissolved Inorganic Carbon）. Geochemical parameters of the groundwater samples were measured either directly in the field or in the laboratory. The results showed that the groundwater from the Holocene and upper Pleistocene aquifers was most recharged from the local meteorological and hydrological systems, including local precipitation, fiver and reservoirs. Thus, it has short transit time and its stable isotopic composition is spread around the local meteoric waterline and lines for rivers or reservoirs water. The groundwater in the deeper aquifers： middle and lower Pleistocene, and Neogene aquifers has old age up to 22.5 ka BP. Its water seems to be recharged from the areas with an altitude from 600 to 700 m higher to the Neogene deposit layer altitude. The groundwater in the SE SP （South-Eastern Southern Plain） region has a high quality. The water type is Na-Ca-Mg-HCO3 with low content of chloride and TDS （Total Dissolved Solids）. Calcite/dolomite and gypsum dissolution, organic matter decomposition and sequence of red-ox reactions proceeding through different electron acceptors sediment were controlled the chemistry of the groundwater in the study region.

关键词： Water isotopic composition ^14C-dating groundwater South-Eastern Southern Plain region Vietnam.

Ecoregional variations of aboveground biomass and stand structure in evergreen broadleaved forests

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Journal of Forestry Research 2020年第5期31卷 1713-1722页

作者： Tran van Do Mamoru Yamamoto Osamu Kozan Vo Dai Hai Phung Dinh Trung Nguyen Toan Thang Lai Thanh Hai Vu Thanh Nam Trieu Thai Hung Hoang van Thang Tran Duc Manh Cao Chi Khiem Vu Tien Lam Nguyen Quang Hung Tran Hoang Quy Pham Quang Tuyen trinh Ngoc Bon Nguyen Thi Thu Phuong Ninh Viet Khuong Nguyen van Tuan Dang Thi Hai Ha Tran Hai Long Dang van Thuyet Dang Thinh Trieu Nguyen van Thinh Tran Anh Hai Duong Quang Trung Nguyen van Bich Dinh Hai Dang Pham Tien Dung Nguyen Huy Hoang Le Thi Hanh Phan Minh Quang Nguyen Thi Thuy Huong Hoang Thanh Son Nguyen Thanh Son Nguyen Thi van Anh Nguyen Thi Hoai Anh Pham Dinh Sam Hoang Thi Nhung Hoang van Thanh Nguyen Huu Thinh Tran Hong van Ho Trung Luong Bui Kieu Hung Research Institute for Sustainable Humanosphere Kyoto UniversityUjiKyotoJapan Silviculture Research Institute Vietnamese Academy of Forest SciencesNorth Tu LiemHanoiVietnam Center for Southeast Asian Studies Kyoto UniversityKyotoJapan Vietnamese Academy of Forest Sciences North Tu LiemHanoiVietnam Vietnam Administration of Forestry No.2 Ngoc HaBa DinhHanoiVietnam

Biotic and abiotic factors control aboveground biomass(AGB)and the structure of forest *** study analyses the variation of AGB and stand structure of evergreen broadleaved forests among six ecoregions of Vietnam.A data set of 1731-ha plots from 52 locations in undisturbed old-growth forests was *** results indicate that basal area and AGB are closely correlated with annual precipitation,but not with annual temperature,evaporation or hours of *** area and AGB are positively correlated with trees>30 cm *** areas surveyed(52.6%)in these old-growth forests had AGB of 100–200 Mg ha^-1;5.2%had AGB of 400–500 Mg ha^-1,and 0.6%had AGB of>800 Mg ha^-*** percent of the areas surveyed had stand densities of 300–600 ***^-1,and 64%had basal areas of 20–40 m^2 ha^-*** is an important factor influencing the AGB of old-growth,evergreen broadleaved forests in *** causing the loss of large-diameter trees(e.g.,>100 cm DBH)affects AGB but may not seriously affect stand density.

关键词： Aboveground biomass Carbon storage Climatic variables Ecoregion Edaphic variables Oldgrowth forest

Using Isotope Technology for Surface Water Environment Research in Southern Hanoi

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Journal of Environmental Protection 2016年第8期7卷 1113-1118页

作者： Vo Thi Anh Tran Khanh Minh trinh van Giap Ha Lan Anh Nguyen Thanh Cong Nguyen Hong Thinh Vu Hoai Institute for Nuclear Science and Technology Hanoi Vietnam Vinh University Vinh Vietnam

The surface water in the southern of Hanoi capital is researched by identifying δ2H and δ18O stable isotopes together with EC, DO, BOD5, COD, TSS. Surface water samples for studying include the Red river, Nhue river and Kim Nguu river, Thanh Nhan lake, Yen So lake and van Quan lake were collected in the dry season (April) and the rainy season (August) in 2015. The stable isotope analysis results showed that the δ18O values is a range from -42.53‰ to -64.05‰ and, the δ2H values is the range from -5.09‰ to -8.79‰ under global meteoric waterline (in the water vapor region). The δ2H results of the rivers and lakes in the dry season are more negative than the rainy season with a small difference. The δ18O results of lakes in the dry season are more negative than the rainy season, but the δ18O results of river in the dry season are more positive than the rainy season. The results of the EC, BOD, COD, DO, TSS analysis showed that surface water environment has changed clearly in the two seasons and the contamination level in the dry season is usually higher than the rainy season. The lakes and rivers strongly influenced by human activities led to seriously pollution are van Quan lake and Yen So lake, Nhue river and Kim Nguu river.

关键词： Isotope Technology Surface Water Quality Change in Difference Seasons