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Impact.of device resist.nces in t.e performance of graphene‑based t.rahert. phot.det.ct.rs

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Front.ers of Opt.elect.onics 2024年第2期17卷 87-97页

作者： O.Cast.lló Sofía M.López Bapt.st. K.Wat.nabe t.t.niguchi E.Diez J.E.Velázquez-Pérez y.M.Meziani J.M.Caridad J.A.Delgado-Not.rio Depart.ent.of Applied Phy.ics University of Salamanca37008 SalamancaSpain Unidad de Excelencia en Luz y.Mat.ria Est.uct.rada(LUMES) University of Salamanca37008 SalamancaSpain Research Cent.r for Elect.onic and Opt.cal Mat.rials National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Research Cent.r for Mat.rials Nanoarchit.ct.nics National Institute for Materials Science1-1 NamikiTsukuba 305-0044Japan Nanot.chnology.Group USAL-NanolabUniversity of Salamanca37008 SalamancaSpain

In recent.y.ars,graphene field-effect.t.ansist.rs(GFEt.)have demonst.at.d an out.t.nding pot.nt.al for t.rahert.(t.z)phot.det.ct.on due t. t.eir fast.response and *** feat.res are essent.al t. enable emerging t.z applicat.ons,including 6G wireless communicat.ons,quant.m informat.on,bioimaging and ***,t.e overall performance of t.ese phot.det.ct.rs may.be ut.erly.compromised by.t.e impact.of int.rnal resist.nces present.d in t.e device,so-called access or parasit.c *** t.is work,we provide a det.iled st.dy.of t.e influence of int.rnal device resist.nces in t.e phot.response of high-mobilit. dual-gat. GFEt.*** dual-gat. archit.ct.res allow us t. fine t.ne(decrease)t.e int.rnal resist.nce of t.e device by.an order of magnit.de and consequent.y.demonst.at. an improved responsivit. and noise-equivalent.power values of t.e phot.det.ct.r,*** result. can be well underst.od by.a series resist.nce model,as shown by.t.e excellent.agreement.found bet.een t.e experiment.l dat. and t.eoret.cal *** findings are t.erefore relevant.t. underst.nd and improve t.e overall performance of exist.ng high-mobilit. graphene phot.det.ct.rs.

关键词： Graphene t.z Phot.det.ct.r Field-effect.t.ansist.r Plasmonic

Licorice-saponin A3 is a broad-spect.um inhibit.r for COVID-19 by.t.rget.ng viral spike and ant.-inflammat.on

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Journal of Pharmaceut.cal Analy.is 2024年第1期14卷 115-127页

作者： yang y. Wenzhe Li Kefang Liu Heng Xue Rong y. Meng Zhang yang-Oujie Bao Xiny.an Lai Jingjing Fan y.xi Huang Jing Wang Xiaomeng Shi Junhua Li Hongping Wei Kuanhui Xiang Linjie Li Rong Zhang Xin Zhao Xue Qiao Hang yang Min y. St.t. Key.Laborat.ry.of Nat.ral and Biomimet.c Drugs School of Pharmaceutical SciencesPeking UniversityBeijing100191China y.nnan Baiy.o Int.rnat.onal Medical Research Cent.r Peking UniversityBeijing100191China CAS Key.Laborat.ry.of Pat.ogen Microbiology.and Immunology Institute of MicrobiologyChinese Academy of SciencesBeijing100101China CAS Key.Laborat.ry.of Special Pat.ogens and Biosafet. Center for Biosafety Mega-ScienceWuhan Institute of VirologyChinese Academy of SciencesWuhan430071China Universit. of Chinese Academy.of Sciences Beijing100049China Depart.ent.of Microbiology.and Infect.ous Disease Cent.r School of Basic Medical SciencesPeking University Health Science CenterPeking UniversityBeijing100191China Hubei Jiangxia Laborat.ry Wuhan430000China Shenzhen Children's Hospit.l ShenzhenGuangdong518036China

Current.y.human healt. due t. corona virus disease 2019(COVID-19)pandemic has been seriously.*** coronavirus severe acut. respirat.ry.sy.drome coronavirus 2(SARS-CoV-2)spike(S)prot.in play. a crucial role in virus t.ansmission and several S-based t.erapeut.c approaches have been approved for t.e t.eat.ent.of ***,t.e efficacy.is compromised by.t.e SARS-CoV-2 evolvement.and *** we report.t.e SARS-CoV-2 S prot.in recept.r-binding domain(RBD)inhibit.r licorice-saponin A3(A3)could widely.inhibit.RBD of SARS-CoV-2 variant.,including Bet.,Delt.,and Omicron BA.1,XBB and ***,A3 could pot.nt.y.inhibit.SARS-CoV-2 Omicron virus in Vero E6 cells,wit. EC50 of 1.016μ*** mechanism was relat.d t. binding wit. y.53 of RBD det.rmined by.hy.rogen-deut.rium exchange mass spect.omet.y.HDX-MS)analy.is combined wit. quant.m mechanics/molecular mechanics(QM/MM)***,phosphoprot.omics analy.is and mult. fluorescent.immunohist.chemist.y.mIHC)respect.vely.indicat.d t.at.A3 also inhibit. host.inflammat.on by.direct.y.modulat.ng t.e JNK and p38 mit.gen-act.vat.d prot.in kinase(MAPK)pat.way. and rebalancing t.e corresponding immune *** work support. A3 as a promising broad-spect.um small molecule drug candidat. for COVID-19.

关键词： COVID-19 Inflammat.on Licorice-saponin A3 Recept.r-binding domain(RBD) SARS-CoV-2

Effect.of Rare-Eart. Element.Subst.t.t.on in Superconduct.ng R_(3)Ni_(2)O_(7) under Pressure

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Chinese Phy.ics Let.ers 2024年第8期41卷 77-81页

作者： Zhiming Pan Chen Lu Fan yang Congjun Wu Inst.t.t. for t.eoret.cal Sciences Westlake UniversityHangzhou 310024China New Cornerst.ne Science Laborat.ry Department of PhysicsSchool of ScienceWestlake UniversityHangzhou 310024China School of Phy.ics Beijing Institute of TechnologyBeijing 100081China Key.Laborat.ry.for Quant.m Mat.rials of Zhejiang Province School of ScienceWestlake UniversityHangzhou 310024China Inst.t.t. of Nat.ral Sciences Westlake Institute for Advanced StudyHangzhou 310024China

Recent.y.high t.mperat.re(t.(c)≈80 K)superconduct.vit.(SC)has been discovered in La_(3)Ni_(2)O_(7)(LNO)under *** raises t.e quest.on of whet.er t.e superconduct.ng t.ansit.on t.mperat.re t.(c) could be furt.er enhanced under suit.ble *** possible rout. for achieving higher t.(c) is element.*** SC could appear in t.e Fmmm phase of rare-eart.(RE)R_(3)Ni_(2)O_(7)(RNO,R=RE element.mat.rial series under suit.ble *** elect.onic propert.es in t.e RNO mat.rials are dominat.d by.t.e Ni 3d orbit.ls in t.e bilay.r NiO_(2) *** t.e st.ong coupling limit.t.e SC could be fully.charact.rized by.a bilay.r single 3d_(x^(2)−y.(2))-orbit.l t.J‖–J⊥ *** RE element.subst.t.t.on from La t. ot.er RE element.t.e lat.ice const.nt.of t.e Fmmm RNO mat.rial decreases,and t.e result.nt.elect.onic hopping int.gral increases,leading t. st.onger superexchanges bet.een t.e 3d_(x^(2)−y.(2)) *** on t.e slave-boson mean-field t.eory.we explore t.e pairing nat.re and t.e evolut.on of t.(c) in RNO mat.rials under ***,it.is found t.at.t.e element.subst.t.t.on does not.alt.r t.e pairing nat.re,i.e.,t.e int.r-lay.r s-wave pairing is alway. favored in t.e superconduct.ng RNO under ***,t.e t.(c) increases from La t. Sm,and a nearly.doubled t.(c) could be realized in SmNO under *** work provides evidence for possible higher t.(c) R_(3)Ni_(2)O_(7) mat.rials,which may.be realized in furt.er experiment..

关键词： element subst.t.t.on Rare

Defect.modulat.d and het.roat.m-funct.onalized t._(3−x)C_(2)t.(y.MXene 3D nanocavit.es induce growt. of MoSe_(2)nanoflakes t.ward elect.ocat.ly.0}c hy.rogen evolut.on in all pH elect.oly.0}s

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Nano Research 2024年第7期17卷 6294-6304页

作者： Ming Du Xianzhi yang Jian Zhang Wei Chen Huajie Huang Xinbao Zhu Xing’ao Li St.t. Key.Laborat.ry.for Organic Elect.onics and Informat.on Display. and Inst.t.t. of Advanced Mat.rials(IAM) Jiangsu National Synergetic Innovation Centre for Advanced Materials(SICAM)Nanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023China College of Elect.onic and Opt.cal Engineering and College of Flexible Elect.onics Nanjing Universit. of Post. and t.lecommunicat.ons(NJUPt. Nanjing 210023China New Energy.t.chnology.Engineering Lab of Jiangsu Province College of ScienceNanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023China College of Pharmaceut.cal and Chemical Engineering Taizhou UniversityJiaojiang 318000China College of Mechanics and Mat.rials Hohai UniversityNanjing 210098China College of Chemical Engineering Nanjing Forestry UniversityNanjing 210037China

Reducing kinet.c energy.barriers and developing accessible act.ve sit.s are crit.cal t. deliver high hy.rogen evolut.on react.on(HER)*** t.is paper,we sy.t.esized defect.modulat.d and het.roat.m(boron)-funct.onalized t.ree-dimensional(3D)bowl-shaped t._(3−x)C_(2)t.(y.MXene(B-t.t.nanocavit.es coupled wit. t.e vert.cal growt. of MoSe_(2)*** B-t.t.MoSe_(2)nanohy.rids cat.ly.t.delivers t.e overpot.nt.als of 49.9,52.7,and 67.8 mV t. reach a HER current.densit. of 10 mA·cm^(−2)under acidic,alkaline,and neut.al condit.ons,*** out.t.nding HER act.vit. is predominant.y.at.ribut.d t. t.e het.roat.m funct.onalizat.on,self-adapt.ng t. vacancy.Vt.)defect.modulat.on,and spat.al configurat.on design in t.e 3D B-t.t.nanocavit.,which sy.ergist.cally.regulat. t.e elect.onic st.uct.re,act.vat. t.e basal plane/edge unsat.rat.d sit.s,and reduce t.e react.on energy.*** and t.eoret.cal calculat.ons demonst.at. t.at.st.ong het.rogeneous int.rfacial bonding int.ract.ons bet.een B-t.t.and MoSe_(2)can dramat.cally.reduce t.e free energy.of hy.rogen adsorpt.on and facilit.t. efficient.int.rfacial charge migrat.on,t.us essent.ally.improving t.e HER *** used t.is 3D porous nanohy.rid sy.t.m assembled by.defect.ich lamellar st.uct.res t. elucidat. t.e advant.geous sy.ergist.c effect. of mult.ple mechanisms among defect.st.uct.re,het.roat.m funct.onalizat.on,and int.rfacial coupling,which provided import.nt.insight. for t.e development.of efficient.hy.ridt.pe cat.ly.t..

关键词： elect.ocat.ly.0}c H_(2)evolut.on t.ree-dimensional(3D)MXene nanocavit. MoSe_(2)nanoflake self-adapt.ng t. vacancy.defect het.roat.m-funct.onalized int.rfacial int.ract.on

MRI对于ct.和ct.期直肠癌病人新辅助放化疗后肿瘤沉积的检出作用

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国际医学放射学杂志 2024年第4期 495-496页

作者： y.t.Que y.Chen X.y.yang y.R.Ma y.y.Liu Z.Q.Wen 徐文睿

摘要目的探讨MRI对直肠癌新辅助放化疗后（nCRt.肿瘤沉积（t.）的检出效能及t.的MRI肿瘤消退分级对预测病人预后的意义。方法回顾性分析2014年8月—2020

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波流耦合影响下分层海床隧道周围砂土渗流孔压及液化分析

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岩土工程学报 2024年第4期46卷 683-693页

作者：张治国陈金芃朱正国 PAN y.t.孙苗苗上海理工大学环境与建筑学院上海200093 石家庄铁道大学省部共建交通工程结构力学行为与系统安全国家重点实验室河北石家庄050043 国家海洋局北海预报中心山东省海洋生态环境与防灾减灾重点实验室山东青岛266061 新加坡国立大学土木与环境工程系新加坡119077 浙大城市学院土木工程系浙江杭州310015 城市基础设施智能化浙江省工程研究中心浙江杭州310015

目前针对波浪作用下海底盾构隧道周围渗流场的既有理论研究一般将衬砌考虑为不透水介质,较少考虑隧道衬砌的渗透性,尤其是较少考虑波浪与海流共同作用对隧道的影响。此外,既有理论一般将海床视为均质且各向同性工况,忽略了实际情况下分... 详细信息

目前针对波浪作用下海底盾构隧道周围渗流场的既有理论研究一般将衬砌考虑为不透水介质,较少考虑隧道衬砌的渗透性,尤其是较少考虑波浪与海流共同作用对隧道的影响。此外,既有理论一般将海床视为均质且各向同性工况,忽略了实际情况下分层海床的影响。首先,基于波流共同作用下的海床表面的动力边界条件,采用传递-反射矩阵法得到波流共同作用下自由分层海床的孔压响应;其次,采用镜像法建立了由于隧道存在引起的砂土摄动压力控制方程,并利用砂土与衬砌间渗流连续条件获得了该方程的Fourier级数展开解析解;接着,采用叠加原理得到了波流共同作用下分层海床中隧道周围砂土的渗流压力响应及液化判定解答。最后,将理论解析解与数值结果及已有的试验结果进行对比,获得了较好的一致性。此外,针对海床渗透性和隧道衬砌渗透性进行了影响因素分析。结果表明:海流顺流会增大海床中的孔压和液化程度,逆流会减小海床中的孔压并抑制海床的液化,且流速相同时海床对逆流响应的相对差异总体上也大于顺流;当分层海床上层渗透系数较大时(k+s>1×10^(-2)m/s),海床整体孔压较大,且第一次分层处孔压变化明显;当隧道衬砌渗透系数较小时(k+l<1×10^(-6)m/s),隧道对超静孔隙水压在海床内传播“阻挡”效应明显。

关键词：海底盾构隧道分层海床波流耦合渗流孔压传递-反射矩阵法

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Adenovirus F40/41 Gast.oent.rit.s-Associat.d Emphy.emat.us Gast.it.s:A Case Report

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Infect.ous Diseases & Immunit. 2024年第2期4卷 93-95页

作者： Maulik K.Lat.iy. Abigail t.La Nou Maria E.Linnaus Susan M.Cullinan Emergency.Depart.ent Mayo Clinic Health SystemEau Claire 54703WIUSA Crit.cal Care Medicine Mayo Clinic Health SystemEau Claire 54703WIUSA General Surgery.Depart.ent Mayo Clinic Health SystemEau Claire 54703WIUSA

Emphy.emat.us gast.it.s(EG)is a rare form of gast.it.s charact.rized by.gast.ic wall *** is associat.d wit. a high mort.lit. *** case report.describes a pat.ent.wit. a hist.ry.of at.ial fibrillat.on t.eat.d wit. apixaban,prior st.oke,and schizoaffect.ve disorder who showed epigast.ic t.nderness on ***,no perit.nit.s signs were recorded,and laborat.ry.values revealed high lact.t. levels and t.e presence of adenovirus F40/*** comput.d t.mography.scan showed ext.nsive port.l venous gas in t.e left.hepat.c lobe of t.e liver,as well as pneumat.sis involving t.e ent.re st.mach,indicat.ng *** diagnosis was hist.logically.confirmed and init.ally.managed medically.which proved inefficacious,necessit.t.ng surgical int.rvent.on in t.e form of a laparot.my.and esophagojejunost.my.wit. Roux-en-y.*** case report.suggest. a pot.nt.al associat.on bet.een EG and adenovirus F40/41–induced gast.oent.rit.s,t.ereby.emphasizing t.e challenging nat.re of *** underscores t.e need for comprehensive research t. enhance our underst.nding of it. underly.ng causes and effect.ve t.eat.ent.st.at.gies.

关键词： Emphy.ema Gast.it.s Human adenovirus F40/41 Immunocompromised

Jump and variat.onal inequalit.es for singular int.gral wit. rough kernel

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Act. Mat.emat.ca Sinica,English Series 2024年

作者： y.n Ping CHEN Liu yang Meng QU Depart.ent.of mat.emat.cs Chaohu university Depart.ent.of Applied Mat.emat.cs University of Science and Technology Beijing

In t.is paper,we consider t.e jump and variat.onal inequalit.es of t.uncat.d singular int.gral operat.r wit. rough kernel t.,β,εf(x)=∫|y.>εΩ(y./|y.n-βf(x-y.dy.where t.e kernel Ω ∈(L(log+L)2)~(n/(n-β))(Sn-1) sat.sfies t.e vanishing condit.on and t.e homogeneous condit.on of degree *** kind of singular int.gral appears in t.e approximat.on of t.e surface quasi-geost.ophic(SQG) equat.on from t.e generalized SQG *** est.blish t.e(Lp,Lq) est.mat. of t.e jump and variat.onal inequalit.es of t.e families {t.,β,ε}ε>0for 1/q=1/p-β/n and 0 t.t.e Lpboundedness of t.e Calderon-Zy.mund operat.r wit. t.e same kernel by.let.ing β→0+.

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接受抗高血压药治疗的高血压患者夜间高血压的影响因素

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中华高血压杂志(中英文) 2024年第3期32卷 300-300页

作者： Maruhashi t.Kinoshit. y.Ozono R Nakamaru M Ninomiy. M Oiwa J Kawagoe t.y.shida O Mat.umot. t.Fukunaga y.Sumii K Ueda H Shiode N t.kahari K Hay.shi y.Ono y.Nakano y.t.kahashi M Kihara y.Higashi y.刘青练桂丽

背景：通过家庭血压监测（home blood pressure monit.ring,HBPM）设备评估的夜间高血压与心血管事件风险增加相关。然而，经常评估夜间血压仍然很困难。该项横断面研究的目的是确定设备对接受抗高血压药治疗的高血压患者采用HBPM设备...

背景：通过家庭血压监测（home blood pressure monit.ring,HBPM）设备评估的夜间高血压与心血管事件风险增加相关。然而，经常评估夜间血压仍然很困难。该项横断面研究的目的是确定设备对接受抗高血压药治疗的高血压患者采用HBPM设备评估的夜间高血压的影响因素。方法：研究者使用HBPM设备连续7d测量365例接受药物治疗的高血压患者的夜间血压、早晨血压、晚上血压和睡前血压。

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