检索结果-南通市图书馆

Response of axillary bud development in garlic(Allium sativum L.) to seed cloves soaked in gibberellic acid(GA3) solution

引用

Journal of Integrative Agriculture 2020年第4期19卷 1044-1054页

作者： LIU Hong-jiu HUANG Cai-ping tong pei-jiang YANG Xue CUI Ming-ming CHENG Zhi-hui College of Horticulture Northwest A&F UniversityYangling 712100P.R.China College of Plant Protection Northwest A&F UniversityYangling 712100P.R.China

Gibberellins(GAs) are important phytohormones that regulate many developmental processes in plants. Clove, as the reproductive organ of garlic, dramatically affected garlic bulb development. Considering the potential of gibberellins in plant development and our previous studies, we investigated the effect of soaking two types of seed cloves(seed clove-I: without root/shoot sprouting;seed clove-II: with root/shoot sprouting) in GA3 solution on axillary bud development and examined the effect of soaking seed cloves in GA3 solution on bulb development, phytohormone level and sugar content in this *** indicated seed clove types, soaking liquids and their interaction significantly affected the number of cloves per bulb and the rate of single-clove bulb. Moreover, soaking seed cloves in 1 mmol L^-1 GA3 solution for 24 h not only promoted axillary bud formation and secondary plant growth(equal to tillering or branching), but also slightly increased the number of cloves per bulb and changed bulb structure with a low yield and marketable quality. On the 40 th day after GA3 treatment(at axillary bud outgrowth stage), zeatin riboside(ZR) and soluble protein in stem were sharply increased with the increase of GA3, sucrose, fructose and soluble protein in leaf. However, GA3, indole-3-acetic acid(IAA), soluble sugar and sucrose in stem(3.52 ng g^-1 fresh weight(FW), 19.88 ng g^-1 FW, 237.3 mg g^-1 FW, and 8.24 mg g^-1 FW, respectively) were significantly decreased on the 40 th day after GA3 treatment, compared to the control of water treatment(5.56 ng g^-1 FW, 32.96 ng g^-1 FW, 263.6 mg g^-1 FW, and 10.37 mg g^-1 FW, respectively). To our knowledge, these novel results indicate seed cloves soaked in GA3 solution promotes axillary bud formation and outgrowth that caused the changes in plant architecture and bulb structure. Meanwhile, our findings suggest that the level of endogenous plant hormone(GA3, IAA and ZR) cooperates with the content of sugar(sucrose and fructose)

关键词： garlic(Allium sativum) gibberellic acid seed clove axillary bud plant hormone sugar

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Cohort study on the treatment of BRAF V600E mutant metastatic colorectal cancer with integrated Chinese and western medicine

引用

World Journal of Clinical Oncology 2025年第1期16卷 25-33页

作者： jiang-Yu Bian Yu-Fang Feng Wen-Ting He tong Zhang Department of Oncology Xiyuan Hospital of China Academy of Chinese Medical SciencesBeijing 100091China Department of Oncology The Fourth Clinical Medical College of Xinjiang Medical UniversityUrumqi 830001China Department of Oncology Traditional Chinese Medicine Hospital Affiliated to Xinjiang Medical UniversityUrumqi 830001China

BACKGROUND Patients with BRAF V600E mutant metastatic colorectal cancer(mCRC)have a low incidence rate,poor biological activity,suboptimal response to conventional treatments,and a poor *** the previous cohort study on mCRC conducted by our team,it was observed that integrated Chinese and Western medicine treatment could significantly prolong the overall survival(OS)of patients with colorectal ***,we further explored the survival benefits in the population with BRAF V600E mutant *** To evaluate the efficacy of integrated Chinese and Western medicine in the treatment of BRAF V600E mutant metastatic colorectal *** A cohort study was conducted on patients with BRAF V600E mutant metastatic colorectal cancer admitted to Xiyuan Hospital of China Academy of Chinese Medical Sciences and Traditional Chinese Medicine Hospital of Xinjiang Uygur Autonomous Region from January 2016 to December *** patients were divided into two *** A total of 34 cases were included,with 23 in Chinese-Western medicine cohort(cohort A)and 11 in Western medicine cohort(cohort B).The median overall survival was 19.9 months in cohort A and 14.2 months in cohort B,with a statistically significant difference(P=0.038,hazard ratio=0.46).The 1-3-year survival rates were 95.65%(22/23),39.13%(9/23),and 26.09%(6/23)in cohort A,and 63.64%(7/11),18.18%(2/11),and 9.09%(1/11)in cohort B,*** analysis showed statistically significant differences in median OS between the two cohorts in the right colon,liver metastasis,chemotherapy,and first-line treatment subgroups(P<0.05).CONCLUSION Integrated Chinese and Western medicine can prolong the survival and reduce the risk of death in patients with BRAF V600E mutant metastatic colorectal cancer,with more pronounced benefits observed in patients with right colon involvement,liver metastasis,combined chemotherapy,and first-line treatment.

关键词： Metastatic colorectal cancer BRAF V600E mutation Integrated Chinese and Western medicine Cohort study

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Hydrogen sulfide reduces oxidative stress in Huntington's disease via Nrf2

引用

Neural Regeneration Research 2025年第6期20卷 1776-1788页

作者： Zige jiang Dexiang Liu Tingting Li Chengcheng Gai Danqing Xin Yijing Zhao Yan Song Yahong Cheng tong Li Zhen Wang Department of Physiology School of Basic Medical SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Medical Psychology and Ethics School of Basic Medicine SciencesCheeloo College of MedicineShandong UniversityJinanShandong ProvinceChina Department of Neurosurgery Surgery Qingdao Municipal HospitalQingdaoShandong ProvinceChina

The pathophysiology of Huntington's disease involves high levels of the neurotoxin quinolinic acid. Quinolinic acid accumulation results in oxidative stress, which leads to neurotoxicity. However, the molecular and cellular mechanisms by which quinolinic acid contributes to Huntington's disease pathology remain unknown. In this study, we established in vitro and in vivo models of Huntington's disease by administering quinolinic acid to the PC12 neuronal cell line and the striatum of mice, respectively. We observed a decrease in the levels of hydrogen sulfide in both PC12 cells and mouse serum, which was accompanied by down-regulation of cystathionine β-synthase, an enzyme responsible for hydrogen sulfide production. However, treatment with NaHS(a hydrogen sulfide donor) increased hydrogen sulfide levels in the neurons and in mouse serum, as well as cystathionine β-synthase expression in the neurons and the mouse striatum, while also improving oxidative imbalance and mitochondrial dysfunction in PC12 cells and the mouse striatum. These beneficial effects correlated with upregulation of nuclear factor erythroid 2-related factor 2 expression. Finally, treatment with the nuclear factor erythroid 2-related factor 2inhibitor ML385 reversed the beneficial impact of exogenous hydrogen sulfide on quinolinic acid-induced oxidative stress. Taken together, our findings show that hydrogen sulfide reduces oxidative stress in Huntington's disease by activating nuclear factor erythroid 2-related factor 2,suggesting that hydrogen sulfide is a novel neuroprotective drug candidate for treating patients with Huntington's disease.

关键词： apoptosis cystathionine-β-synthase nuclear factor erythroid 2-related factor 2 Huntington's disease hydrogen sulfide mitochondrion neuroplasticity oxidative stress quinolinic acid reactive oxygen species

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of ultrasonic-assisted extraction on bioactive compounds,volatile flavors and antioxidant activities of vine tea water extracts

引用

Traditional Medicine Research 2025年第1期10卷 73-81页

作者： Xiao-Long Zhou Wei-Jin jiang Ji Yu Mao-Jun Yao Yun-tong Li Hunan Provincial Key Laboratory of Research Resource Mining and High-valued Utilization on Edible&Medicinal PlantCollege of Chemistry and Chemical EngineeringJishou UniversityJishou 416000China Hunan Gaoge Dairy Co. Ltd.Changsha 410000China

Background:Ampelopsis grossedentata,vine tea,which is the tea alternative beverages in *** vine tea processing,a large amount of broken tea is produced,which has low commercial ***:This study investigates the influence of different extraction methods(room temperature water extraction,boiling water extraction,ultrasonic-assisted room temperature water extraction,and ultrasonic-assisted boiling water extraction,referred to as room temperature water extraction(RE),boiling water extraction(BE),ultrasonic assistance at room temperature water extraction(URE),and ultrasonic assistance in boiling water extraction(UBE))on the yield,dihydromyricetin(DMY)content,free amino acid composition,volatile aroma components,and antioxidant properties of vine tea ***:A notable influence of extraction temperature on the yield of vine tea extracts(P<0.05),with BE yielding the highest at 43.13±0.26%,higher than that of RE(34.29±0.81%).Ultrasound-assisted extraction significantly increased the DMY content of the extracts(P<0.05),whereas DMY content in the RE extracts was 59.94±1.70%,that of URE reached 66.14±2.78%.Analysis revealed 17 amino acids,with L-serine and aspartic acid being the most abundant in the extracts,nevertheless ultrasound-assisted extraction reduced total free amino acid *** chromatography-mass spectrometry analysis demonstrated an increase in the diversity and quantity of compounds in the vine tea water extracts obtained through ultrasonic-assisted ***,69 and 68 volatile compounds were found in URE and UBE extracts,which were higher than the number found in RE and BE *** vitro,antioxidant activity assessments revealed varying antioxidant capacities among different extraction methods,with RE exhibiting the highest DPPH scavenging rate,URE leading in ABTS•+free radical scavenging,and BE demonstrating superior ferric ion reducing antioxidant ***:The findings suggest that extraction methods signi

关键词： vine tea dihydromyricetin ultrasonic-assisted extraction volatile aroma components

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A novel architecture of electro-hydrostatic actuator with digital distribution

引用

Chinese Journal of Aeronautics 2021年第5期34卷 224-238页

作者： Jing YAO pei WANG Zhaosheng DONG Dongting jiang tong SHA School of Mechanical Engineering Yanshan UniversityQinhuangdcio 066004China Key Laboratory of Advanced Forging&Stamping Technology and Science of Ministry of Education of China Ycmshan UniversityQinhuangdao 066004China Hebei Key Laboratory of Heavy Machinery Fluid Power Transmission and Control Ycmshan UniversityQinhuangdao 066004China

To address the flow imbalance rapidly of the asymmetric Electro-Hydrostatic Actuator(EHA),this paper presents a novel architecture of asymmetric EHA with the Digital Distribution(EHA-DD).It also improves the flow nonlinearity and control accuracy of the pump,especially in the low-speed *** digital distribution with two High-Speed on–off Valves(HSVs)not only balances flow instead of the check valves,but also replaces the pump at the low-speed to control output flow by adjusting the PWM *** pump and HSVs are the crucial components to control flow ***,the flow calculation models of the pump and the duty ratio inversed model of the HSV are obtained through experimental tests and the identification *** get the control input signal for the required flow,the pump speed and PWM duty ratio for the HSVs are inversed to compensate for flow ***,a multimode digital flow distribution control method based on pump speed,mainly including the pump-controlled mode for large flow demand and valve-controlled mode for little flow demand,is proposed to control the accurate flow output *** step extension experiments based on the flow calculation models are conducted on the EHA-DD prototype under elastic,opposite varying *** results demonstrate that the EHADD realizes little position error by accurate flow control,and it is also beneficial to improve the service life of the pump.

关键词： Asymmetrical flow Digital distribution EHA High-speed on–off valve Nonlinearity PWM control

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

电刺激诱导miR-741-3p调控Radil促进施万细胞的迁移

引用

中国组织工程研究 2025年第19期29卷 4038-4043页

作者：刘庆高博杨霄姜宇王培承德医学院附属医院河北省承德市067000 承德医学院河北省承德市067000

背景:越来越多的动物实验和临床研究证实电刺激可以促进周围神经损伤修复,具体的机制尚未完全明确。目的:探讨电刺激诱导miR-741-3p调控Radil对施万细胞迁移的影响。方法:①12只雄性SD大鼠,随机分为电刺激组和对照组,电刺激组在坐骨神... 详细信息

背景:越来越多的动物实验和临床研究证实电刺激可以促进周围神经损伤修复,具体的机制尚未完全明确。目的:探讨电刺激诱导miR-741-3p调控Radil对施万细胞迁移的影响。方法:①12只雄性SD大鼠,随机分为电刺激组和对照组,电刺激组在坐骨神经挤压伤后连续电刺激7 d,对照组在坐骨神经挤压后不做任何处理。术后第7天取损伤处神经,利用荧光原位杂交技术检测两组miR-741-3p的表达差异。②通过miRDB、TargetScan和miRWalk数据库预测miR-741-3p靶基因。③将miR-741-3p模拟物及其对照、miR-741-3p抑制物及其对照、Radil siRNA及其对照、miR-741-3p抑制物+Radil siRNA及miR-741-3p抑制物+siRNA对照对施万细胞进行转染,采用RT-PCR检测转染效率,Transwell小室检测施万细胞的迁移能力。结果与结论:①电刺激组神经残端miR-741-3p荧光强度低于对照组;②数据库预测结果显示有69个基因可能是miR-741-3p靶基因,Radil是预测靶基因之一,主要参与细胞黏附和迁移;③与miR-741-3p抑制物对照组相比,miR-741-3p抑制物组施万细胞迁移数增多(P<0.05);与miR-741-3p模拟物对照组相比,miR-741-3p模拟物组施万细胞迁移数减少(P<0.05);与siRNA对照组相比,Radil siRNA组施万细胞迁移数减少(P<0.05);④与miR-741-3p抑制物对照组相比,miR-741-3p抑制物组Radil的表达水平升高;与miR-741-3p模拟物对照组相比,miR-741-3p模拟物组Radil的表达水平降低;⑤与miR-741-3p抑制物+siRNA对照组相比,miR-741-3p抑制物+Radil siRNA组施万细胞迁移数减少(P<0.05)。结果表明,电刺激通过下调miR-741-3p调控Radi的表达来促进施万细胞迁移。

关键词：施万细胞电刺激 miR-741-3p Radil 细胞迁移神经再生

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Understanding the mechanisms of resistance to tomato leaf mold:A review

引用

Horticultural Plant Journal 2022年第6期8卷 667-675页

作者： Tingting Zhao tong pei Jingbin jiang Huanhuan Yang He Zhang Jingfu Li Xiangyang Xu Key Laboratory of Biology and Genetic Improvement of Horticultural Crops(Northeast Region) Ministry of Agriculture and Rural AffairsCollege of Horticulture and Landscape ArchitectureNortheast Agricultural UniversityHarbin 150030China

Tomato leaf mold is a common disease in tomato production and severely impacts the growth,fruit quality and yield of tomato *** on tomato leaf mold has a long history and has focused mainly on the differentiation of pathogen races,the structure and function of pathogen Avr gene products,the cloning of Cf resistance genes and the analysis of disease resistance *** between Cf and Avr are in accordance with the"gene-for-gene"hypothesis and typical Cf/Avr interactions are part of effector-triggered immunity(ETI).However,an increasing number of studies have proven that pathogen-associated molecular pattern(PAMP)-triggered immunity(PTI)is involved in the disease resistance response system mediated by Cf *** addition,different Cf genes have both similar and different roles in the disease resistance response,indicating that the disease resistance mechanism of Cf genes is *** this paper,progress in tomato leaf mold research was reviewed,and the regulatory mechanism underlying the Cf-mediated disease resistance response was thoroughly *** hope this summary will lay a foundation for research on tomato leaf mold disease resistance mechanisms and is applicable to breeding for disease resistance.

关键词： Tomato leaf mold Cf genes Disease resistance Cf/Avr interactions

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Using ecosystem service supply and ecosystem sensitivity to identify landscape ecology security patterns in the Lanzhou-Xining urban agglomeration, China

引用

Journal of Mountain Science 2020年第11期17卷 2758-2773页

作者： tong Hua-li SHI pei-ji College of Geography and Environmental Science Northwest Normal UniversityLanzhou 730070China Gansu Province Land Use and Comprehensive Improvement Engineering Research Center Lanzhou 730070China

The construction of an ecological security pattern(ESP)is an important way to ensure regional ecological security and to achieve sustainable regional *** is also one of the hotspot topics of landscape ecology *** paper identifies the ecological source through the evaluation of the ecosystem service and ecosystem sensitivity of the Lanzhou-Xining(Lan-Xi)urban *** minimum cumulative resistance(MCR)model modified by night light data NPP/VIIRS(National Polar-orbiting Operational Environmental Satellite System Preparatory Project/Visible Infrared Imaging Radiometer Suite)was used to measure the relative resistance of the materials and energy circulation between the source areas,and to establish the resistance surface of the ecological source area *** ecological corridors were identified based on ecological sources and resistance *** ecological strategic node is the ecological fragile point in the ecological *** ecological strategic node is identified with hydrological module by superimposing the"ridge line"of cumulative ecological resistance with the ecological *** with ecological sources,corridors and strategic nodes,the ESP of the Lan-Xi urban agglomeration can be *** ecological source of the Lan-Xi urban agglomeration accounts for 28.42%of the total area,most of which is distributed within Qinghai *** nature reserves in the area are all located within the ecological source area.A total of 41 potential ecological corridors have been identified in the study *** total length of the potential corridors is 1201.03 km,comprising 23 source corridors and 18 radiation *** are 30 strategic nodes identified in the Lan-Xi urban *** locations are the most vulnerable areas of the ecological *** engineering should be applied in the construction of *** by the ecological source,the potential ecological corridor extends from

关键词： Ecological security pattern Ecosystem service Ecosystem sensitivity Ecological source Ecological corridor Urban agglomeration

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Role of Solute Rare Earth in Altering Phase Transformations during Continuous Cooling of a Low Alloy Cr–Mo–V Steel

引用

Acta Metallurgica Sinica(English Letters) 2023年第9期36卷 1523-1535页

作者： Zhonghua jiang pei Wang Dianzhong Li Shenyang National Laboratory for Materials Science Institute of Metal ResearchChinese Academy of SciencesShenyang110016China

Effects of solute rare earth(RE)on continuous cooling transformation of a low-alloy Cr–Mo–V bainitic steel are investigated in detail by dilatometry,optical microscopy(OM),scanning electron microscopy(SEM)and transmission electron microscopy(TEM).Microstructures appeared in thermal dilatometric samples of both low-alloy Cr–Mo–V(RE)steels are composed of quasi-polygonal ferrite(QPF),degenerate pearlite(DP),granular bainite(GB),lath bainite(LB),and martensite(M)depending on cooling *** cooling rate is lower than 2°C/s,the addition of RE suppresses QPF transformation,and thereby inducing a broader transformation region of *** cooling rate ranges from 2 to 100°C/s,the addition of RE decreases the start temperature of bainitic transformation distinctly,which results in finer bainitic ferrite grain size and higher dislocation *** addition of RE can enhance the hardness of the low alloy Cr–Mo–V steel by affecting the aforementioned diffusional and/or partly displacive ***,when cooling rate increases up to 150°C/s,two steels have the same hardness value of about 435 HV due to only martensite obtained by displacive transformation.

关键词： Low-alloy Cr-Mo-V steel Rare earth Phase transformation Bainitic microstructures Continuous cooling transformation

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Nonlinear Tripartite Entangled State Representation and Related Generalized Wigner Function

引用

Communications in Theoretical Physics 2005年第3X期44卷 541-546页

作者： WANG pei-Qing SONG tong-Qiang Physics Department Ningbo University Ningbo 315211 China

We construct the nonlinear tripartite entangled state representation and the related generalized Wigner operator. Then we discussed the Wigner functions of the nonlinear tripartite entangled state and the three-mode nonlinear squeezed vacuum state, and obtained the classical Weyl corresponding function of the three-mode nonlinear squeezed state.

关键词： nonlinear entangled states generalized Wigner operator IWOP technique

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：