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Interaction between encapsulated microbubbles:A finite element modelling study

Chinese Physics B 2018年第8期27卷 315-323页

作者： Chen-Liang Cai Jie Yul Juan Tu Xia-Sheng Guo Pin-tong huang Dong Zhang Key Laboratory of Modem Acoustics（MOE） Department of PhysicsCollaborative Inovation Center of Advanced Microstructure Nanjing UniversityNanjing 210093China Department of Ultrasound the Second Affiliated Hospital of Zhejiang University School of MedicineHangzhou 310009China The State Key Laboratory of Acoustics Chinese Academy of SciencesBeijing 100190China

Theoretical studies on the multi-bubble interaction are crucial for the in-depth understanding of the mechanism behind the applications of ultrasound contrast agents （UCAs） in clinics. A two-dimensional （2D） axisymmetric finite element model （FEM） is developed here to investigate the bubble-bubble interactions for UCAs in a fluidic environment. The effect of the driving frequency and the bubble size on the bubble interaction tendency （viz., bubbles＇ attraction and repulsion）, as well as the influences of bubble shell mechanical parameters （viz., surface tension coefficient and viscosity coefficient） are discussed. Based on FEM simulations, the temporal evolution of the bubbles＇ radii, the bubble-bubble distance, and the distribution of the velocity field in the surrounding fluid are investigated in detail. The results suggest that for the interacting bubble-bubble couple, the overall translational tendency should be determined by the relationship between the driving frequency and their resonance frequencies. When the driving frequency falls between the resonance frequencies of two bubbles with different sizes, they will repel each other, otherwise they will attract each other. For constant acoustic driving parameters used in this paper, the changing rate of the bubble radius decreases as the viscosity coefficient increases, and increases first then decreases as the bubble shell surface tension coefficient increases, which means that the strength of bubble-bubble interaction could be adjusted by changing the bubble shell visco-elasticity coefficients. The current work should provide a powerful explanation for the accumulation observations in an experiment, and provide a fundamental theoretical support for the applications of UCAs in clinics.

关键词： ultrasound contrast agent microbubbles bubble-bubble interaction finite element model shellparameter

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A New Type of Polymer-Supported Metallocene Catalyst for Ethylene Polymerization

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Chinese Chemical Letters 2001年第3期12卷 257-260页

作者： Guang Qian YU De Ze ZHANG Fu SHUN Li Jun QIAO Tao TANG Bao tong huang State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesPolymer Chemistry LaboratoryChemistry Academy of Sciences and China Petro-Chemical CorporationChangchun 130022

A new polymer-supported metallocene catalyst has been prepared, The polymer-supported metallocene displayed considerably high activity in ethylene polymerization, the highest being 3.62x10(7) gPE/molZr.h, the molecular weight of the polyethylene produced was Mn = 1.29x10(5). about 3-4 times those of corresponding homogeneous zirconocenes. The polymer-supported metallocene keeps the characteristics of homogeneous metallocene catalysts, and offers some features, such as adaptable to gas phase and slurry processes: easy to prepare in low cost: relatively high activity and lower MAO/Zr ratio; lower inorganic residues in the polyolefins as compared to cases of SiO2, Al2O3 or MgCl2; unitary active structure, no complex surface as with SiO2; good control of morphology of the resulting polymer.

关键词： Polymer-support metallocene catalyst ethylene polymerization

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Treatment strategies for hepatocellular carcinoma with extrahepatic metastasis

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World Journal of Clinical Cases 2021年第21期9卷 5754-5768页

作者： Hai-Yi Long tong-Yi huang Xiao-Yan Xie Jian-Ting Long Bao-Xian Liu Department of Medical Ultrasonics Institute of Diagnostic and Interventional Ultrasoundthe First Affiliated Hospital of Sun Yat-Sen UniversityGuangzhou 510080Guangdong ProvinceChina Department of Medical Oncology The First Affiliated Hospital of Sun Yat-sen UniversityGuangzhou 510080Guangdong ProvinceChina

Extrahepatic metastasis(EHM)of hepatocellular carcinoma(HCC)has increasingly been seen due to improved survival with effective management of intrahepatic *** presence of EHM indicates an advanced stage of HCC,for which systemic therapy serves as the standard treatment *** the approval of Sorafenib as the first systemic agent in 2007,it took almost a decade to show its efficacy in both first and further lines of setting until the landscape of systemic drugs was finally ***,with inspiring results from immunotherapy trials in HCC,it appears that the introduction of immunotherapy may lead to an evolution in the portfolio of HCC *** the locoregional approach in the management of EHM is not recommended for advancedstage HCC,efforts have been made to demonstrate its efficacy in symptom relief and potential benefit for overall *** review provides a summary of recent updates of the systemic agents in the treatment of advanced HCC,with an emphasis on aggressive locoregional management of EHM by various treatment modalities.

关键词： Hepatocellular carcinoma Extrahepatic metastasis Systemic therapy Targeted therapy Immunotherapy Locoregional therapy

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Design of Scenery Complementary Solar Water Heater Based cm Eddy Current Method

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International Journal of Technology Management 2014年第7期 27-30页

作者： huang tong Electrical and Electronic Engineering School North China Electric Power University Baoding 071003 China

This paper uses scenery complementary heating method to discuss a new type of scenery complementary water heater design. This product can be divided into two parts. The first part is the eddy current method wind power heating part, which is driven by wind power and vertical axis wind turbines and the design of magnet array rotor disc rotation, namely, magnetic field rotating, induced eddy current in the stator, so as to generate heat. The second part is the solar heating part. This works has broad market prospect, which provides a new idea for large-scaled heating method.

关键词： eddy current method scenery complementary solar water heater

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Toward alkaline‑stable anion exchange membranes in fuel cells:cycloaliphatic quaternary ammonium‑based anion conductors

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Electrochemical Energy Reviews 2022年第2期5卷 348-400页

作者： Jiandang Xue Junfeng Zhang Xin Liu tong huang Haifei Jiang Yan Yin Yanzhou Qin Michael D.Guiver State Key Laboratory of Engines Tianjin UniversityTianjin 300072China Key Laboratory for Green Chemical Technology Ministry of Education of ChinaSchool of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Collaborative Innovation Center of Chemical Science and Engineering(Tianjin) Tianjin 300072China

Anion exchange membrane(AEM)stability has been a long-standing challenge that limited the widespread development and adoption of AEM fuel cells(AEMFCs).The past five years have been a period of exceptional progress in the development of several alkaline-stable AEMs with remarkable both ex situ and in situ AEMFC *** cycloaliphatic quaternary ammonium(cQA)(mainly five-and six-membered)based AEMs appear to be among those having the most promising overall *** this review,we categorize cQAs as cage-like(such as quaternized 1,4-diazabicyclo[2.2.2]octane,(QDABCO)and quinuclidinium),non-cage-like(such as pyrrolidinium and piperidinium)and N-spirocyclic(such as 6-azonia-spiro[5.5]undecane(ASU)).The degradation mechanisms of categorized cQAs are first *** an understanding of how the cations are attacked by strongly nucleophilic OH–,improved structural design of incorporating alkaline-stable cations into AEMs is *** a detailed description and comparison of the alkaline stability of cQAs and their respective AEMs,current protocols for the assessment of alkaline stability are discussed in ***,the initial AEMFC performance and fuel cell performance stability based on cQA AEMs are also *** main focus and highlight of this review are recent advances(2015–2020)of cQA-based AEMs,which exhibit both excellent cation and membrane alka-line *** aim to shed light on the development of alkaline-stable cQA-type AEMs,which are trending in the AEM community,and to provide insights into possible solutions for designing long-lived AEM materials.

关键词： Fuel cells Anion exchange membrane Alkaline stability Cycloaliphatic quaternary ammonium

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Predicting transformer temperature field based on physics-informed neural networks

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High Voltage 2024年第4期9卷 839-852页

作者： Pengfei Tang Zhonghao Zhang Jie tong Tianhang Long Can huang Zihao Qi China Electric Power Research Institute BeijingChina

The safe operation of oil-immersed transformers is critical to the safety and stability of the power *** the operating time increases,the failure rate of oil-immersed transformers shows an increasing trend,posing serious challenges to safe *** is necessary to investigate the internal state of the oil-immersed transformer to improve the digital degree and achieve digitalisation and intelligent operation and maintenance.A physics-informed neural network(PINN)for oil-immersed transformers was introduced to reconstruct the temperature distribution inside the *** to the approach,the loss function of the network would be optimised by incorporating physical constraint loss terms including heat transfer equations,initial conditions and boundary *** results show that the method proposed can be used to reconstruct and predict the temperature field of transformers in a few seconds with satisfactory *** conclusion,the PINN proposed outperforms deep neural networks in terms of accuracy,reliability and interpretability,especially in data-poor cases.

关键词： immersed conclusion constraint

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Research and Application of Probability Distribution of Wind Power Fluctuation Characteristics

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International Journal of Technology Management 2014年第4期 28-32页

作者： huang tong College of Electrical and Electronic Engineering North China Electric Power University Baoding 071003 China

The fluctuation characteristics is the inherent property of wind *** analysis of a large number of wind t＇anns based on measured data,we find it describes the best probability distribution of wind power fluctuation for the mixed Gauss distribution of two components,and try to carry out the physical interpretation of two *** discussion is between the probability distribution of fluctuating wind power time difference and whole *** is found that the two have basic *** comparing the different time level data quantified losses the information of wind power fluctuation,quantitative determination of the degree of impact *** can summarize and understand of wind power fluctuation,constructing instance from the wind farm construction and monitoring prediction two aspect recommendations to overcome the adverse effects of wind power fluctuations on the power grid operation.

关键词： wind power fluctuation characteristics probability distribution gauss mixture distribution:

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In vivo 3-photon fluorescence microscopy of white matter in mouse brain excited at the 1700 nm window

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Journal of Innovative Optical Health Sciences 2024年第5期17卷 81-87页

作者： Jie huang Jincheng Zhong Shen tong Yingxian Zhang Ping Qiu Ke Wang Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province College of Physics and Optoelectronic EngineeringShenzhen UniversityShenzhen 518060P.R.China School of Medical Information and Engineering Xuzhou Medical UniversityXuzhou 221004P.R.China

White matter,a densely packed collection of myelinated axons,plays an essential part in neural *** high spatial resolution and deep penetration,multi-photon microscopy(MPM)is promising for white matter imaging in animal models in *** third harmonic generation(THG)signal can be generated from white matter,but the bottom part of the white matter layer generates weak THG due to its high ***,we demonstrate an in vivo labeling and imaging technology,capable of visualizing the white matter layer in the mouse brain,combining°uorescence labeling with MitoTracker Red and three-photon°uorescence(3PF)microscopy excited at the 1700 nm window.3PF signals are several times higher than THG signals,resulting in deeper imaging of the white matter layer with the *** results indicate that 3PF microscopy is a promising technology for white matter imaging in the deep brain in vivo.

关键词： Three-photon microscopy white matter myelin MitoTracker Red

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Exploring the Interplay between Local Chain Structure and Stress Distribution in Polymer Networks

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Chinese Journal of Polymer Science 2024年第6期42卷 874-885页

作者： Jin-tong Xue Yang Bai Li Peng Xian-Bo huang Zhao-Yan Sun School of Applied Chemistry and Engineering University of Science and Technology of ChinaHefei230026China State Key Laboratory of Polymer Physics and Chemistry Changchun Institute of Applied ChemistryChinese Academy of SciencesChangchun130022China National-certified Enterprise Technology Center Kingfa Science and Technology Co.Ltd.Guangzhou510663China

The mechanical behavior of polymer networks is intrinsically correlated with the local chain topology and chain *** this study,we delve into this relationship through the lens of coarse-grained molecular dynamics(CG-MD)*** aim is to illuminate the intricate interplay between local topology and stress distribution within polymer monomers,cross-linkers,and various components with distinct cross-link connections,thereby elucidating their collective impact on the mechanical properties of polymer *** mainly focus on how specific local structures contribute to the overall mechanical response of the *** particular,we employ local stress analysis to unravel the mechanics of these *** findings reveal the diverse responses of individual components,such as junctions,strands,cross-linkers between junctions,and dangling chain ends,when subjected to ***,we observe that these components exhibit varying degrees of deformation tolerance,underscoring the significance of their roles in determining the mechanical characteristics of the *** investigations highlight junctions as primary contributors to stress accumulation,and particles with higher local stress showing a stronger correlation between stress and Voronoi ***,our results indicate that both strands and cross-linkers between junctions exhibit heightened stress levels as strand lengths *** study enhances our understanding of the multifaceted factors governing the mechanical attributes of cross-linked polymer systems at the microstructural level.

关键词： Local chain structure Local stress Molecular dynamics simulation

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Development of a low-loss magnetic-coupling pickup for 166.6-MHz quarter-wave beta=1 superconducting cavities

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Nuclear Science and Techniques 2020年第9期31卷 25-32页

作者： tong-Ming huang Pei Zhang Zhong-Quan Li Xin-Ying Zhang Hai-Ying Lin Qiang Ma Fan-Bo Meng Wei-Min Pan Institute of High Energy Physics Chinese Academy of SciencesBeijing 100049China Key Laboratory of Particle Acceleration Physics and Technology IHEPCASBeijing 100049China School of Nuclear Sciences and Technology University of Chinese Academy of SciencesBeijing 100049China

166.6-MHz quarter-waveβ=1 superconducting cavities have been adopted for the High Energy Photon Source,a 6-GeV diffraction-limited synchrotron light source currently under construction.A large helium jacket was required to accommodate the enlarged cavity beam pipe for the heavy damping of higher-order modes;the original electric-probe pickup thus becomes inevitably long with unfavorable mechanical *** to an existing high-pressure-rinsing port,a magnetic-loop pickup was designed,characterized by low radio-frequency and cryogenic losses and being multipacting-free and insensitive to manufacturing and assembly *** consequent removal of the original pickup port from the cavity largely simplified the helium jacket fabrication and may also reduce cavity *** paper presents a comprehensive design of a low-loss magnetic-coupling pickup for quarter-waveβ=1 superconducting *** design can also be applied to other non-elliptical structures.

关键词： Pickup Magnetic coupling Quarter-wave cavity Superconducting cavity Low loss Synchrotron light source

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