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Modulation of phase boundary and domain structures to engineer strain properties in BNT-based ferroelectrics

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Journal of Advanced Ceramics 2024年第7期13卷 967-975页

作者： Yule Yang Zhiyong Liu Pengrong Ren Yuqing mao Haijun Sun Bingliang Liang Pu mao Kun Guo Bing Xie Longlong Shu School of Materials Science and Engineering Nanchang Hangkong UniversityNanchang 330063China School of Materials Science and Engineering Xi'an University of TechnologyXi’an 710048China School of Aircraft Engineering Nanchang Hangkong UniversityNanchang 330063China School of Physics and Materials Science Nanchang UniversityNanchang 330031China

Bismuth sodium titanate(BNT)ceramics exhibit outstanding strain responses but are unfavorable for application in high-sensitivity displacement actuators due to the large negative strain resulting from irreversible changes in their phase transition and domain ***,(1−x)Bi_(0.50)Na_(0.41)K_(0.09)TiO_(3)-xNaNbO_(3)(BNKT−xNN)solid solutions were prepared to improve the strain properties through the strategy of modulating the phase boundary and domain *** introduction of sodium niobate could effectively regulate the relative content of the tetragonal(P4bm)and rhombohedral(R3c)phases in the phase boundary *** ferroelectric-to-relaxor phase transition(TF−R)was reduced,and the ergodic relaxor(ER)state was nurtured at room *** zero-negative strain properties of S=0.41%and d33*=742 pm/V were achieved from the reversible transition between the ER and ferroelectric states under an applied electric field(x=0.04).Additionally,understanding the domain states via piezoelectric force microscopy(PFM)and firstorder reversal curve(FORC)revealed that the superior strain responses originated from the reversible inter-transformation of substable macrodomains and polar nanoregions(PNRs)in the phase *** study provides new insight into the interplay between the evolution of phase boundaries and domain structures and the strain properties of BNT-based ceramics.

关键词： bismuth sodium titanate(BNT) domain structure phase boundary strain response relaxor state

Improved Segmented Belief Propagation List Decoding for Polar Codes with Bit-Flipping

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China Communications 2024年第3期21卷 19-36页

作者： mao Yinyou Yang Dong Liu Xingcheng Zou En School of Electronics and Information Technology(SEIT) Sun Yat-sen University(SYSU)Guangzhou 510006China School of Information Science Guangzhou Xinhua UniversityGuangzhou 510520China Southern Marine Science and Engineering Guangdong Laboratory(Zhuhai) Zhuhai 519080China

Belief propagation list(BPL) decoding for polar codes has attracted more attention due to its inherent parallel nature. However, a large gap still exists with CRC-aided SCL(CA-SCL) *** this work, an improved segmented belief propagation list decoding based on bit flipping(SBPL-BF) is proposed. On the one hand, the proposed algorithm makes use of the cooperative characteristic in BPL decoding such that the codeword is decoded in different BP decoders. Based on this characteristic, the unreliable bits for flipping could be split into multiple subblocks and could be flipped in different decoders simultaneously. On the other hand, a more flexible and effective processing strategy for the priori information of the unfrozen bits that do not need to be flipped is designed to improve the decoding convergence. In addition, this is the first proposal in BPL decoding which jointly optimizes the bit flipping of the information bits and the code bits. In particular, for bit flipping of the code bits, a H-matrix aided bit-flipping algorithm is designed to enhance the accuracy in identifying erroneous code bits. The simulation results show that the proposed algorithm significantly improves the errorcorrection performance of BPL decoding for medium and long codes. It is more than 0.25 d B better than the state-of-the-art BPL decoding at a block error rate(BLER) of 10^(-5), and outperforms CA-SCL decoding in the low signal-to-noise(SNR) region for(1024, 0.5)polar codes.

关键词： belief propagation list(BPL)decoding bit-flipping polar codes segmented CRC

Can whole steps of grain production be outsourced? Empirical analysis based on the three provinces of Jiangsu,Jilin,and Sichuan in China

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Journal of Integrative Agriculture 2024年第1期23卷 336-347页

作者： Jiacheng Liu Shengzhi mao Qiufen Zheng Zhigang Xu School of Finance and Taxation Nanjing University of Finance and EconomicsJiangsu 210023China School of Economics Southwestern University of Finance and EconomicsSichuan 611130China School of Economics and Management Nanjing Agricultural UniversityJiangsu 210095China

Certain outsourcing services for agricultural management in China,such as pest control in grain production,have experienced prolonged sluggishness,contrasting with the relatively high level of outsourcing services observed in harvesting,land preparation,and *** study examines the feasibility of implementing whole-step outsourcing in grain production by conducting a case study of rice and maize production in Jiangsu,Jilin,and Sichuan provinces in *** provision of outsourcing services hinges on two essential conditions:technological advancements fostering specialized production and economies of scale,coupled with a market size sufficient to realize the aforementioned potential economies of *** results showed that outsourcing pest control or harvesting services had varying economies of *** outsourcing services in pest control were less common than in harvesting services,and their marginal growth space of the economies of scale with technological change was also *** by the operational characteristics of pest control itself,the market scale of its professional services is ***,achieving the whole-step outsourcing of grain production necessitates not only technological innovation but also effective policy interventions to overcome the constraints of market *** interventions include(1)optimizing crop layouts between planning regions and reducing land fragmentation and(2)supplying timely and effective inter-regional agricultural information for service providers aided by information technology.

关键词： outsourcing services economy of scale technical conditions market scale

On a Flexible Loan Repayment Method Depending on Borrower's Asset with an Early Termination Clause

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Acta Mathematicae Applicatae Sinica 2024年第2期40卷 557-567页

作者： Jin LIANG Jia-qi mao Zhao-ya LIU School of Mathematical Sciences Tongji UniversityShanghai 200092China

Aiming at the problem that the asset’s fluctuation influences the borrower’s repayment ability,a loan with a new and flexible repayment method is designed,which depends on the asset value of the *** repayment method can reduce the loan default probability,but it causes the uncertainty of the pay off *** the repayment term is related to the regular repayment amount in this method,a boundary for the regular repayment amount is set up in order to avoid too long repayment *** will balance the benefit of borrowers and lenders and improve the applicability of this *** establishing a mathematical model of the residual value of the loan,this model can be transformed into an initial-boundary problem of a partial differential *** analytic solution and the expected time to pay off the loan are ***,numerical analysis are shown.

关键词： flexible repayment method repayment ratio early termination clause expected pay off time

Area Operators on Bergman Spaces

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Acta Mathematica Sinica,English Series 2024年第5期40卷 1161-1176页

作者： Xiao Fen LV Jordi PAU mao Fa WANG Department of Mathematics Huzhou UniversityHuzhou 313000P.R.China Departament de Matemàtiques i Informàtica Universitat de Barcelona08007 BarcelonaCataloniaSpain School of Mathematics and Statistics Wuhan UniversityWuhan 430072P.R.China

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0 详细信息

We completely characterize the boundedness of area operators from the Bergman spaces A_(α)^(p)(Bn)to the Lebesgue spaces L^(q)(S_(n))for all 0

关键词： Area operator Bergman space tent space area formula

Research trends in pharmacogenomics of immune diseases:A bibliometric study

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Clinical Research Communications 2024年第3期7卷 13-22页

作者： Xue-ting mao Hong-ting Nie Guan-Ru Chen Xiao-Ling Wang Xiao-Lin Xu Department of Pharmacy Beijing Children's HospitalCapital Medical UniversityNational Center for Children’s HealthBeijing 100045China. Department of Clinical Pharmacology School of Pharmaceutical SciencesCapital Medical UniversityBeijing 100069China. Department of Clinical Pharmacy Anhui Provincial Children's HospitalHefei 230000China.

Background:Numerous academic studies have explored the utilization of pharmacogenomics in the context of immunologic diseases in recent *** this,there is a notable absence of scientometric analyses focusing on the literature within this ***:This study employs bibliometric methods to systematically categorize the literature pertaining to pharmacogenomics in the context of immune diseases,with the aim of identifying research trends,key areas of interest,and prominent research institutions in this ***:Scientometric analysis compared 812 international publications with 71 Chinese publications,finding that the prevailing international research focus is on the precise dosing and therapy of immunosuppressants like mercaptopurine,a topic more extensively explored than in Chinese ***:It is found that the research focus is centered on precision medication and therapy,with a particular emphasis on the utilization of different immunosuppressants like mercaptopurine and ***,it is anticipated that precision dosing of emerging immunosuppressants like sirolimus will be a significant are a of future research.

关键词： pharmacogenomics immunization American Science Citation Index Online Edition bibliometrics analysis CiteSpace

The posterior selection method for hyperparameters in regularized least squares method

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Control Theory and Technology 2024年第2期22卷 184-194页

作者： Yanxin Zhang Jing Chen Yawen mao Quanmin Zhu School of Science Jiangnan UniversityWuxi214122JiangsuChina The Science and Technology on Near-Surface Detection Laboratory Wuxi214122JiangsuChina Department of Engineering Design and Mathematics University of the West of EnglandBristolBS161QYUK

The selection of hyperparameters in regularized least squares plays an important role in large-scale system identification. The traditional methods for selecting hyperparameters are based on experience or marginal likelihood maximization method, which are inaccurate or computationally expensive. In this paper, two posterior methods are proposed to select hyperparameters based on different prior knowledge (constraints), which can obtain the optimal hyperparameters using the optimization theory. Moreover, we also give the theoretical optimal constraints, and verify its effectiveness. Numerical simulation shows that the hyperparameters and parameter vector estimate obtained by the proposed methods are the optimal ones.

关键词： Regularization method Hyperparameter System identification Least squares algorithm

Heat stress induced hepatocyte apoptosis in largemouth bass Micropterus salmoides via IRE1α/TRAF2/ASK1/JNK pathway

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Journal of Oceanology and Limnology 2024年第3期42卷 988-1000页

作者： Xuqian ZHAO Wenjia mao Zijie LIN Qufei LING School of Biology and Basic Medical Sciences Suzhou Medical College of Soochow UniversitySuzhou 215000China

Heat stress(HS)has been shown to adversely affect fish livers and can lead to extensive *** investigate the relationship between endoplasmic reticulum(ER)stress and HS-induced apoptosis in fish livers,we isolated and cultured primary hepatocytes of largemouth bass,Micropterus salmoides by trypsin method,then established an in-vitro model of liver cells under HS(35℃).The contents of lactic dehydrogenase(LDH)and hydrogen peroxide(H2O2)were determined to evaluate the effects of HS on hepatocyte injury and oxidative ***-qPCR was performed to discover the key genes in unfolded protein response(UPR)pathways involved at different HS *** inhibitor 4-PBA and IRE1αinhibitor 4μ8C were used to further investigate the effects of HS on IRE1αapoptosis pathway in *** show that HS led to significant increases in the release of LDH,the content of H2O2,and the expressions of oxidative protein folding genes(ero1αand pdi)under HS,suggesting severe hepatocyte injury and oxidative stress happened in heat-stressed largemouth bass *** continuous activation of IRE1αpathway genes(grp78,grp94,atf6,perk,eif2a,atf4,chop,ire1α,traf2,ask1,jnk1,and jnk2)indicated that HS led significantly to ER *** particular,the mRNA expression levels of ER stress-related genes(grp78,grp94,atf6,perk,ire1α,chop,jnk1,and jnk2)in the high temperature(HT)+4-PBA group and the HT+4μ8C group were significantly down-regulated under *** 4μ8C treatment,the expression levels of apoptosis-related genes(caspase-2,caspase-3,caspase-6,caspase-7,caspase-8,caspase-9,and caspase-10)and LDH content were significantly decreased,whereas the cell survival rate was significantly increased when given 4-PBA or 4μ8C *** findings demonstrate that HS could induce liver apoptosis of largemouth bass through the IRE1αpathway,which may act as a key switch mediating liver apoptosis of largemouth bass under HS.

关键词： heat stress Micropterus salmoides endoplasmic reticulum stress apoptosis oxidative stress

NHE7 upregulation potentiates the uptake of small extracellular vesicles by enhancing maturation of macropinosomes in hepatocellular carcinoma

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Cancer Communications 2024年第2期44卷 251-272页

作者： Yue Yao Yi Xu Liang Yu ting-mao Xue Zhi-Jie Xiao Pui-Chi Tin Hiu-Ling Fung Hoi-Tang Ma Jing-Ping Yun Judy Wai Ping Yam Department of Pathology School of Clinical MedicineLi Ka Shing Faculty of MedicineThe University of Hong KongHong KongP.R.China Department of Endocrinology and Metabolism Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjingP.R.China Department of Hepatopancreatobiliary Surgery Second Affiliated Hospital of Harbin Medical UniversityHarbinHeilongjingP.R.China State Key Laboratory of Oncology in South China Cancer Center of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China Department of Hepatobiliary Surgery II Zhujiang HospitalSouthern Medical UniversityGuangzhouGuangdongP.R.China Scientific Research Center The Seventh Affiliated HospitalSun Yat-sen UniversityShenzhenGuangdongP.R.China State Key Laboratory of Liver Research The University of Hong KongHong KongP.R.China Department of Pathology Cancer Center of Sun Yat-sen UniversityGuangzhouGuangdongP.R.China

Background:Small extracellular vesicles(sEVs)mediate intercellular commu-nication that contributes to hepatocellular carcinoma(HCC)progression via multifaceted *** success of cell entry determines the effect of sEV on recipient ***,we aimed to delineate the mechanisms underlying the uptake of sEV in ***:AF,Alexa Fluor;ANOVA,analysis of variance;ATP9A,ATPase Phospholipid Transporting 9A;BCECF-AM,2’,7’-bis-(2-barboxyethyl)-5-(and-6)-carboxyfluorescein,acetoxymethyl ester;BSA,bovine serum albumin;CCMR,Centre for Comparative Medicine Research;CRISPR,clustered regularly interspaced short palindromic repeats;CTL,ctrl;CXCR4,C-X-C Chemokine Receptor Type 4;DAPI,4′,6-diamidino-2-phenylindole;DFS,disease-free survival;DMEM,Dulbecco’s Modified Eagle Medium;DMSO,dimethyl sulfoxide;Dox,doxycycline;EEA1,early endosome antigen 1;EIPA,5-(N-ethyl-N-isopropyl)-amiloride;FBS,fetal bovine serum;FITC,fluorescein isothiocyanate;GAPDH,glyceraldehyde-3-phosphate dehydrogenase;GM130,Golgi matrix protein 130;HCC,hepatocellular carcinoma;HEPES,4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid;HPRT1,hypoxanthine phosphoribosyltransferase 1;H-score,histoscore;IAA,indole-3-acetic acid;KD,knockdown;KO,knockout;mAID,mini-auxin-inducible degron;MTT,3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide;NHE7,Na(+)/H(+)exchanger 7;ns,non-significant;OD,optical density;OS,overall survival;PBS,phosphate-buffered saline;PCR,polymerase chain reaction;pHe,endosomal pH;pHi,intracellular pH;PKH67,Paul Karl Horan 67;Rab21,Ras-associated binding protein 21;RIPA,radioimmunoprecipitation assay;SAM,synergistic activation mediator;SEMs,standard error of the means;sEVs,small extracellular vesicles;sgRNA,single-guide RNA;shRNA,short-hairpin RNA;SLC9,solute carrier gene 9;SLiCE,Seamless Ligation Cloning Extract;TCGA,The Cancer Genome Atlas;TCL,total cell lysates;TGN,trans-Golgi network;TMA,tissue microarray;TMR,tetramethyl rhodamine;TSG101,tumor susceptibility gene *** Yao an

关键词： hepatocellular carcinoma small extracellular vesicles macropinocytosis pH regulation sodium-hydrogen exchanger