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小蘖鹼对细菌的抗生作用及其机制的初步研究

生理学报 1957年第3期 213-224页

作者：蓝天鹤徐仲吕侯助存梅行刘宗定林志靖杜寿昌杜水仙四川医学院生物化学教研组四川医学院微生物学教研组四川医学院微生物学教研组成都

黄连在祖国医学中应用甚早而广泛,1917年日本学者若林发现小蘖鹼封大腸桿菌、伤寒桿菌、及霍乱弧菌有抑制作用,1928年苏联学者发现植物殺菌素,此後即有许多学者研究植物的抗生物质,在祖国及日本等国亦有学者研究黄連浸膏及小蘖鹼的抗生... 详细信息

黄连在祖国医学中应用甚早而广泛,1917年日本学者若林发现小蘖鹼封大腸桿菌、伤寒桿菌、及霍乱弧菌有抑制作用,1928年苏联学者发现植物殺菌素,此後即有许多学者研究植物的抗生物质,在祖国及日本等国亦有学者研究黄連浸膏及小蘖鹼的抗生作用,並碓定小蘖鹼为黄连主要抗生成份。但小蘖鹼对细菌抗生作用的机制則尚无报告,因此作者们从川产黄連中提取小蘖鹼,並作了若干种氨基酸、维生素和其他物质封小蘖鹼有无拮抗作用的研究,从而初步探讨其对金黄色葡萄球菌的抗生机制,此外,又研究了福氏痢疾桿菌,及溶血性链球菌对小蘖鹼的抗药性等。

关键词：金黄色葡萄球菌尼克酸生素烟酸抗生作用小粟

5-羟基嘧啶——Ⅳ.5-烷氧基-5-烷基-2-硫代巴比酸和有关化合物的合成

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化学学报 1965年第6期 502-508页

作者：黄湘舲周政陶鏡蓉錢瑞卿陸大荇王真陈立滇伍少蘭張滂北京大学化学系北京大学化学系 1956年毕业生 1957年毕业生 1962年毕业生 1963年毕业生

自烷氧基乙酸乙酯的乙氧草酰化,继以热裂去羰化反应,合成了一系列烷氧基丙二酸二乙酯(Ⅵ,R=n-C3H7,n-C4H9,iso-C4H9,iso-C5H11和C6H5CH2);进一步烷基化,得到烷氧基烷基丙二酸二乙酯（Ⅶ,R′=CH3,C2H5,n-C3H7和n-C4H-9）。烷氧基烷基丙... 详细信息

自烷氧基乙酸乙酯的乙氧草酰化,继以热裂去羰化反应,合成了一系列烷氧基丙二酸二乙酯(Ⅵ,R=n-C3H7,n-C4H9,iso-C4H9,iso-C5H11和C6H5CH2);进一步烷基化,得到烷氧基烷基丙二酸二乙酯（Ⅶ,R′=CH3,C2H5,n-C3H7和n-C4H-9）。烷氧基烷基丙二酸二乙酯（Ⅶ）与脲、硫脲和与胍的缩合的容易程度相差颇巨。除苯甲氧基乙基丙二酸二乙酯曾与脲缩合生成相应的5,5-二取代巴比酸（I,Y=O）外,其他的各烷氧基烷基丙二酸二乙酯（Ⅶ）均未能与脲顺利地发生缩合。各烷氧基烷基丙二酸二乙酯（Ⅶ）与硫脲的缩合效果较佳,但其中仍有若干未能得到所期望的2-硫代巴比酸（I,Y=S）。两个系列的烷氧基烷基丙二酸二乙酯（Ⅶ,R=n-C3H7和C6H5CH2;R′=CH3,C2H5,n-C3H7,和n-C4H9）与胍的缩合非常顺利,生成相应的5,5-二取代-2-亚氨基巴此酸（I,Y=NH）。5-苯甲氧基-5-烷基-2-亚氨基巴比酸还进行了氢解,得到相应的5-羟基-5-烷基-2-亚氰基巴比酸（I,R=H,R′=烷基,Y=NH）。

关键词：烷氧基代巴缩合烷基取代基丙二酸二乙酯化合物

Preliminary studies on the resistance of pepper accessions AvRDC PBC81（Capsicum baccatum） and PBC932（***） to Colletotrichum acutatum

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Preliminary studies on the resistance of pepper accessions A...

海峡两岸第十届菌物学暨第三届食药用菌学术研讨会

作者： CHEN Ying-Ru~1 LIN Ying-Hong~1 WANG tien-Chen~(2,3,4) SHEU Zong-Ming~2 CHEN Yuhsin~5 KUO Ker-Chung~6 CHANG Pi-Fang Linda~(1,*) 1 Department of Plant Pathology,Chung Hsing University,taichung City 40227,taiwan 2 AvRDC-the World vegetable Center,Shanhua,tainan City 74199,taiwan 3 Known-You Seed Co.,Ltd.,Kaohsiung City 80271,taiwan 4 Evergrow Seed Co.,Ltd.,tainan City 70252,taiwan 5 Department of Bioscience technology,Chang Jung Christian University.Kway Jen,tainan City 71101,taiwan 6 Bureau of Animal and Plant Health Inspection and Quarantine,Council of Agriculture,Executive Yuan,taipei City 10075,taiwan

＜正＞Pepper（Capsicum sp.） belongs to the family Solanaceae,and its main harvest areas in the world are India,thailand, Indonesia,Mexico,Japan,Sudan,Nigeria,Kenya,and *** are one of the most popular spices and vegetables *** major pepper production regions of taiwan are in Nantou,Pingtung,Chiayi,Yunlin,tainan,Kaohsiung,and Hualian. Pepper was reported to be one of the important food crops used as spice-additives in *** acutatum Simmonds, ***（Penz.） Sacc,***（Syd.） Butl.＆ Bisby,and *** are the causal agents of pepper anthracnose, and usually lead to significant loss in fruit quality and yields *** disease causing a great deal of fruit reduction has been reported in India,North America,and tropical ***,it is considered an economically important disease of *** date,few environmentally safe and efficacious methods to protect crops from anthracnose disease have been *** addition,the commercial pepper cultivars used in taiwan are mostly susceptible to *** of the pepper anthracnose primarily depended on the frequent applications of fungicides which had adverse effects on environmental pollution,people health, and farmer ***,the most secure ways to manage anthracnose disease at present is based on the development of resistant lines,and planting resistant cultivars to increase the quality and yield of pepper and at the same time to reduce the use of chemical *** the resistance mechanism of pepper against anthracnose will provide some hints to develop efficacious crop protection strategies and also reduce the time needed for resistance breeding program in the ***,little information is available on resistance mechanisms of pepper to anthracnose so *** advanced understanding of interactions between pepper and pathogen can lead to the establishment of more efficient management *** order to eluc

关键词： anthracnose Colletotrichum acutatum pepper resistant accession disease symptoms

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人类腹主动脉瘤腔内血栓铁吞噬的MRI研究

国际医学放射学杂志 2010年第3期 277-278页

作者：倪鸣飞 A. Nchimi O. Defawe D. Brisbois t.K.Y. Broussaud J.O. Defraigne P. Magotteaux Department of Medical Imaging Centre Hospitalier Chrétien

摘要目的前瞻性研究超顺磁性氧化铁(SPIO)MRI增强扫描检测人类腹主动脉瘤内血栓白细胞的吞噬能力。材料与方法本研究

关键词：血栓 MRI SPIO 腔内腹主动脉瘤人类

variability in precipitation,temperature and river runoff in West Central Asia during the past-2000 years

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地球环境学报 2011年第1期 320-320页

作者： Oberhnsli H Novotná K Písková A Chabrillat S Nourgaliev D K Kurbaniyazov A K Grygar t Helmholtz-Centre Potsdam German Geoscience Centre(GFZ)TelegraphenbergD-14473 PotsdamGermany Institute of Inorganic Chemistry of the ASCR v.v.i.250 68 RezCzech Republic Faculty of Science Charles University in PragueCzech Republic Faculty of Geology Kazan State UniversityKazanTatarstanRussia Federation420008Russia Ahmed Yasawi International Kazakh-turkish University TurkestanKazakhstan

the tributary rivers Amu Darya and Syr Darya contribute major amounts of water to the hydrological budget of the endorheic Aral *** controlling the flow of water into rivers in the headwater systems in tien Shan（Kyrgyzstan） and Pamir（tajikistan） are therefore most *** water mineralization is strongly dependent on river discharge and has been inferred from spectrometrically determined gypsum *** of highresolution mineralization data with other proxies for tracing precipitation in NW China indicate that mineralization over the past;000 years in the Aral Sea reflects snow cover variability and glacier extent in tien Shan and Pamir（at the NW and W edges of the tibetan Plateau）.Snow cover in W Central Asia is preferentially a winter expression controlled by temperature patterns that impact the moisture-loading capacity over N Europe and NW *** observed that the runoff,resulting from warmer winter temperatures in W Central Asia and resulting in a reduction of snow cover,decreased between AD 100-300,AD 1150-1250,AD 1380-1450,AD 1580-1680 and during several low frequency events after AD 1800.

关键词： Asia variability in precipitation,temperature and river runoff in West Central Asia during the past-2000 years AD

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我国正常成年学生血液化学成分的测定

生理学报 1957年第3期 244-252页

作者：李韻笙朱惠通郑葆芬顧天爵何开玲王雪英张丽丽朱伯明申功述梅美珍李亮上海第一医学院生化教研组上海第一医学院生化教研组上海

血液化学成分的常数是檢查人体健康与营养状况以及诊断疾病的重要参考资料。测定我国人民血液化学成分的常数,以林樹模的报告为最早,测定的项目与人数也较多。但作者未曾严格规定条件作为血样品选择的标准。我们考虑到年龄、性别、营养... 详细信息

血液化学成分的常数是檢查人体健康与营养状况以及诊断疾病的重要参考资料。测定我国人民血液化学成分的常数,以林樹模的报告为最早,测定的项目与人数也较多。但作者未曾严格规定条件作为血样品选择的标准。我们考虑到年龄、性别、营养与其他有关健康的条件,选出我医学院中正常成年学生数百人这血样品供给者,进行了15种血液成分的测定:血清总蛋白、白蛋白与球蛋白、纤维蛋白元、非蛋白氮、脲氮、尿酸、肌酸与肌酐、血糖、血清总胆固醇、胆固醇酯、游离胆固醇、钙与无机磷。这些工作是1955

关键词：常数非蛋白氮团人男生数学血液成分血清白蛋白胆固醇醋血糖血滤液