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Chinese Chemical Letters 2017年第5期28卷 935-942页

作者： Yong Zhang jia-Yi Zhu Hong-Bo Ren Yu-tie Bi Lin Zhang Department of Physics University of Sdence and Technology of ChinaHefei 230026China Joint Laboratory for Extreme Conditions Matter Properties Southwest University of Science and Technology and Research Center of Laser FusionMianyang621010China Science and Technology on Plasma Physics Laboratory Research Center of Laser FusionChina Academy of Engineering PhysicsMianyang 621900China

Three-dimensional porous nitrogen-doped graphene aerogels（NGAs） were synthesized by using graphene oxide（GO） and chitosan via a self-assembly process by a rapid *** morphology and structure of the as-prepared aerogels were *** results showed that NGAs possesed the hierarchical pores with the wide size distribution ranging from mesopores to *** NGAs carbonized at different temperature all showed excellent electrochemical performance in 6 mol/L KOH electrolyte and the electrochemical performance of the NGA-900 was the *** working as a supercapacitor electrode,NGA-900 exhibited a high specific capacitance（244.4 F/g at a current density of 0.2 A/g）,superior rate capability（51.0% capacity retention） and excellent cycling life（96.2% capacitance retained after 5000 cycles）.

关键词： Nitrogen-doped graphene aerogels Hierarchical porous structure Carbonizing temperature Supercapacitors Energy storage and conversion

Mechanism underlying Fanmugua(Fructus Caricae)leaf multicomponent synergistic therapy for anemia:data mining based on hematopoietic network

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Journal of Traditional Chinese Medicine 2023年第3期43卷 542-551页

作者： jia Lihong tie Defu FAN Zhaohui CHEN Dan CHEN Qizhu CHEN Jun BO Huaben School of Bioscience and Biopharmaceutics Guangdong Province Key Laboratory for Biotechnology Drug CandidatesGuangdong Pharmaceutical UniversityGuangdong 510006China Department of Pharmacy Zhanjiang Health School of GuangdongGuangdong 524037China College of Pharmacy Guangdong Pharmaceutical UniversityGuangdong 510006China

OBJECTIVE:To investigate the underlying mechanism of Fanmugua(Fructus Caricae) Leaf(CPL) multicomponent synergistic therapy for ***:The components were identified in the *** databases were searched for targets of *** analysis was used to determine the targets associated with anemia and in bone *** on the Kyoto Encyclopedia of Genes and Genomes database,pathways and targets related to hematopoiesis were *** key targets were obtained by protein-protein interaction *** docking was used to analyze the binding ability of key targets and active *** marrow cells were used as an experimental model to verify the drug ***:A total of 139 components and 1868 targets of CPL were retrieved from the *** disease enrichment analysis,543 targets for hemorrhagic anemia,223 targets for aplastic anemia,and 126 targets for sickle cell anemia were *** organ enrichment yielded 27,29,and 20 targets of bone *** on KEGG pathway enrichment,a total of 47 shared hematopoietic pathways and 42 related targets were *** key targets were vascular endothelial growth factor A(VEGFA),interleukin 10(IL-10),plateletendothelial cell adhesion molecule-1(PECAM1),C-C motif chemokine 2(CCL2),and vascular cell adhesion molecule 1(VCAM1).The CPL active components included ursolic acid,quercetin,and *** expression of VEGFA was significantly increased after CPL *** and ursolic acid acted on *** and Hesperidin acted on *** acted on IL-10,CCL2,VCAM1,and *** experiments revealed that CPL could promote the proliferation and migration of bone marrow ***:CPL has the synergistic efficacy of treating anemia through multiple components,targets,and pathways.

关键词： anemia data mining network pharmacology molecular docking simulation Carica papaya(Fructus Caricae)Leaf synergistic effect

Significance of 125I radioactive seed implantation on growth differentiation factor and programmed death receptor-1 during treatment of oral cancer

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World Journal of Clinical Cases 2020年第5期8卷 874-886页

作者： gang Xue Yao Feng jia-Bin Li Department II of Prosthodontics The Second Affiliated Hospital of Jiamusi UniversityJiamusi 154000Heilongjiang ProvinceChina Department I of Endodontics The Second Affiliated Hospital of Jiamusi UniversityJiamusi 154000Heilongjiang ProvinceChina Department II of Oral and Maxillofacial Surgery The Second Affiliated Hospital of Jiamusi UniversityJiamusi 154000Heilongjiang ProvinceChina

BACKGROUND Oral cancer(OC)is the most common malignant tumor in the oral cavity,and is mainly seen in middle-aged and elderly *** present,OC is mainly treated clinically by surgery or combined with radiotherapy and chemotherapy;but recently,more and more studies have shown that the stress trauma caused by surgery and the side effects of radiotherapy and chemotherapy seriously affect the prognosis of *** To determine the significance of 125I radioactive seed implantation on growth differentiation factor 11(GDF11)and programmed death receptor-1(PD-1)during treatment of *** A total of 184 OC patients admitted to The Second Affiliated Hospital of jiamusi University from May 2015 to May 2017 were selected as the research subjects for prospective *** these patients,89 who received 125I radioactive seed implantation therapy were regarded as the research group(RG)and 95 patients who received surgical treatment were regarded as the control group(CG).The clinical efficacy,incidence of adverse reactions and changes in GDF11 and PD-1 before treatment(T0),2 wk after treatment(T1),4 wk after treatment(T2)and 6 wk after treatment(T3)were compared between the two *** The efficacy and recurrence rate in the RG were better than those in the CG(Ptients with *** therapy has marked potential in clinical *** detection of GDF11 and PD-1 in patients during treatment showed good predictive value for treatment efficacy and recurrence in OC patients,and may be poten

关键词： 125I radioactive seeds Oral cancer Growth differentiation factor 11 Programmed death receptor-1 Prognosis Recurrence

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法国英语教材价值观呈现研究

外语学刊 2025年第1期 78-85页

作者：谈佳北京外国语大学法语语言文化学院北京100089

本文梳理了法国阿歇特出版社中学英语教材Teen Time的价值观呈现方式。研究发现,教材选择呈现的价值元素,不仅对应欧洲价值观调查揭示的法国人坚持的价值观,同时也是英语素材所承载的目的语国家所认同的价值观,反复出现的“社团活动、... 详细信息

本文梳理了法国阿歇特出版社中学英语教材Teen Time的价值观呈现方式。研究发现,教材选择呈现的价值元素,不仅对应欧洲价值观调查揭示的法国人坚持的价值观,同时也是英语素材所承载的目的语国家所认同的价值观,反复出现的“社团活动、规则意识、文化多样性和生态保护”,反映出在与他人、与社会以及与自然关系上法国与英语国家的共同态度和期许。Teen Time通过标题引领、图文呼应和文化板块拓展深入的呈现方式,传递价值观,并设置层层任务,让学习者在行动中体验,将价值观内化于心、外化于行,实现外语教学的育人功能,其价值观的选取角度和呈现方式对我国中学外语教材的编写具有一定的借鉴意义。

关键词：价值观呈现方式法国英语教材中学行动中体验

Deriving Energy-Level Gap of a System in Presence of a Kerr-like Medium by Virtue of Invariant Eigen-operator Method

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Communications in Theoretical Physics 2006年第4期45卷 614-616页

作者： GUI Wei-Jun GUI jia-Zhang TANG gang Department of Machinery and Electronic Engineering Nanchang institute of Technology Nanchang 330099 China

In this paper, we find the invariant eigen-operators （IEOs） and the energy-level gap of a system with a two-level atom interacting with single mode cavity field through multi-photon transition in the presence of a Kerr-like medium. From this work, one can see that the IEO method in many eases is simpler and easier on obtaining the energy-level gap formula than the usual way.

关键词： energy-level gap Kerr-like medium invariant eigen-operator

High performance lithium oxygen batteries based on a phosphorous-doped holey graphene cathode

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Rare Metals 2022年第12期41卷 4027-4033页

作者： Ying Meng jia-Kui Zhang Hai-Ying Lu Xiang-Hong Chen jian-tie Xu National Engineering Laboratory for VOCs Pollution Control Technology and Equipment Guangdong Provincial Key Laboratory of Atmospheric Environment and Pollution ControlSchool of Environment and EnergySouth China University of TechnologyGuangzhou 510640China

The sluggish electrochemical kinetics of cathode is one of the critical issues for the development of high performance lithium oxygen batteries(LOBs).Graphene-based materials have attracted great attentions as advance... 详细信息

关键词： lithium performance kinetics

A framework for identifying the onset of landslide acceleration based on the exponential moving average(EMA)

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Journal of Mountain Science 2023年第6期20卷 1639-1649页

作者： WANG jia-zhu JU Neng-pan tie Yong-bo BAI Yong-jian GE Hua State Key Laboratory of Geohazard Prevention and Geoenvironment Protection(SKLGP) Chengdu University of TechnologyChengdu 610059China Chengdu Center of China Geological Survey Chengdu 610081China

Predicting the failure time of a landslide is considered as challenging work in the field of landslide research,and inverse velocity is proved to be an effective and convenient *** onset of acceleration(OOA)has a crucial effect on the prediction failure time from the inverse velocity ***,a simple method to identify OOA points is lacked,and most of the identifications rely on expert ***,this study presents an application of a simple framework developed to identify the OOA by analyzing monitoring velocity data in three steps,including selection of the absolute value of velocity,reliable area identification and OOA identification.A new parameter based on exponential moving average(EMA)is developed to identify the landslide *** framework is applied to three historical case studies to test its practicability and *** forecasting results show a good correspondence between the accuracy rate and the coefficient of determination(R2).The predicted failure time according to the linear extrapolation starting from the identified OOA points is acceptable with a high R2 and high accuracy.

关键词： Landslides failure time Acceleration Inverse velocity method Monitoring Tertiary creep phase

Effect of Al content on modification behavior of non-metallic inclusions in high-strength steel treated with rare earth

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Journal of Iron and Steel Research International 2024年第8期31卷 1886-1899页

作者： Zhan-peng tie Xue-yuan jiang Hai-yan Tang ·Gen Li Yu-hang Wang jia-quan Zhang School of Metallurgical and Ecological Engineering University of Science and Technology BeijingBeijing 100083China Continuous Casting Business Section CISDI Engineering Co.Ltd.Chongqing 401122China Special Steel Institute Central Iron and Steel Research Institute Co.Ltd.Beijing 100081China

The influence of Al content(0.0053,0.0171,and 0.0578 wt.%)on the modification behavior of non-metallic inclusions in 20CrMoVTiB steel treated with rare earth elements was studied through high-temperature experiments and thermodynamic *** results showed that the modification products varied with the Al content in steel under 0.01 wt.%of Ce *** formation sequence of typical rare earth inclusions in steel with the increase in Al content was Ce_(2)O_(3)→CeAlO_(3)→CeAl_(11)O_(18),and the final stable products were highly Al content *** the Al content was 0.0053 wt.%,the stable phase in steel was Ce2O3;while the[Al]reached 0.0171 wt.%,the stable phase became CeA1O_(3).As the A1 content reached 0.0578 wt.%,CeAl_(11)O_(18) became the stable *** a result,increasing the Al content could inhibit the precipitation of Ce_(2)O_(3) inclusions in steel while promote the formation of CeAIO3 and CeAl_(11)O_(18) *** addition,both Ca treatment and Ce treatment could effectively refine the size of inclusions in steel by changing their ***,the feeding amount of Ca wire into molten steel should be appropriately reduced under the condition of adding Ce simultaneously,which is expected to be beneficial for an improved Ce treatment effect.

关键词： Rare earth Al content Steel Inclusion Thermodynamics Ca treatment

Sensor network architecture for intelligent high-speed train on-board monitoring

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Journal of Zhejiang University-Science A(Applied Physics & Engineering) 2011年第12期12卷 921-925页

作者： Xiao-fan WU Chun CHEN jia-jun BU gang CHEN College of Computer Science Zhejiang University Hangzhou 310027 China

The China's high-speed railway is experiencing a rapid *** operating mileage and the number of operating trains will exceed 45 000 km and 1500 trains by 2015,*** the long range and constant high-speed operation,the high-speed trains have extremely complex and varied work *** a situation creates a huge demand for high-speed train on-board *** this paper,architecture for high-speed train on-board monitoring sensor network is *** architecture is designed to achieve the goals of reliable sensing,scalable data transporting,and easy *** three design goals are realized *** reliable sensing is achieved by deploying redundant sensor nodes in the same *** a hierarchal transporting scheme is involved to meet the second ***,an electronic-tag based addressing method is introduced to solve the management problem.

关键词： High-speed train On-board monitoring Sensor network Network architecture

Structure of precursor micro RNA＇s terminal loop regulates human Dicer＇s dicing activity by switching DExH/D domain

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Protein & Cell 2015年第3期6卷 185-193页

作者： Zhongmin Liu jia Wang gang Li Hong-Wei Wang Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Peking University Health Science Center Beijing 100191 China Tsinghua-Peking Joint Center for Life Sciences School of Life Sciences Tsinghua University Beijing 100084 China

Almost all pre-miRNAs in eukaryotic cytoplasm are recognized and processed into double-stranded microRNAs by the endonuclease Dicer protein comprising of multiple domains. As a key player in the small RNA induced gene silencing pathway, the major domains of Dicer are conserved among different species with the exception of the N-terminal components. Human Dicer＇s N-terminal domain has been shown to play an autoinhibitory function of the protein＇s dicing activity. Such an auto-inhibition can be released when the human Dicer protein dimerizes with its partner protein, such as TRBP, PACT through the N-terminal DExH/D （ATPase- helicase） domain. The typical feature of a pre-miRNA contains a terminal loop and a stem duplex, which bind to human Dicer＇s DExH/D （ATPase-helicase） domain and PAZ domain respectively during the dicing reaction. Here, we show that pre-miRNA＇s terminal loop can regulate human Dicer＇s enzymatic activity by interacting with the DExH/D （ATPase-helicase） domain. We found that various editing products of pre-miR-151 by the ADAR1P110 protein, an A-to-I editing enzyme that modifies pre-miRNAs sequence, have different terminal loop structures and different activity regulatory effects on human Dicer. Single particle electron microscopy reconstruction revealed that pre-miRNAs with different terminal loop structures induce human Dicer＇s DExH/D （ATPase-helicase） domain into different conformational states, in correlation with their activity regulatory effects.

关键词： human Dicer DExH/D (ATPase-helicase)domain pre-miRNA-151 A-to-I editing single particle electron microscopy