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Evaluation of a model for providing cost effective,accessible continuing education to the forensic science community

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Forensic Sciences Research 2021年第4期6卷 224-230页

作者： thomas j.Gluodenis Department of chemistry&Physics Lincoln UniversityLincoln UniversityPAUSA

This study presents a detailed model and its subsequent assessment for the development and optimized delivery of continuing education for the forensic science *** continuing education is on the rise as this modality of content dissemination allows for accessibility,convenience,and *** model,which includes an educational needs assessment,gap analysis,online content delivery and archival,was evaluated through the launch of a global training event/symposium *** four-year study of over 6000 participants representing>75 countries provides empirical support for the model based upon registration/attendance data and participant self-assessment *** practices are identified relative to content and format,operational excellence,technology,and financing of the *** directions along with opportunities to further enhance the model are also discussed.

关键词： Forensic sciences continuing education educational requirements online web-based certification

Solid-state emissive biphenylene bridged bisaroyl-S,N-ketene acetals as distinct aggregation-induced enhanced emitters and fluorometric probes

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Aggregate 2021年第5期2卷 179-184页

作者： Lukas Biesen thomas j.j.Muller Institut fur Organische und Makromolekulare Chemie Heinrich-Heine-Universitat DusseldorfDüsseldorfGermany

Biphenylene bridged bisaroyl-S,N-ketene acetals can be readily synthesized by a one-pot Masuda borylation-Suzuki arylation sequence,thus,yielding a library of 20 bisaroyl-S,N-ketene acetals with tunable solid-state emission and aggregationinduced enhanced emission characteristics depending on the para substituents in the starting *** applications as fluorometric probe of alcoholic beverages are outlined.

关键词： aggregation-induced emission aroyl-S N-ketene acetals liquor sensors one-pot reaction solid-state

Prospective,multicentre study of screening,investigation and management of hyponatraemia after subarachnoid haemorrhage in the UK and Ireland

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Stroke & Vascular Neurology 2023年第3期8卷 207-216,I0028-I0059页

作者： james j M Loan Steven Tominey Kirun Baweja julie Woodfield thomas j G Chambers Mark Haley Simran S Kundu H Y josephine Tang Anthony N Wiggins Michael T C Poon Paul M Brennan Translational Neurosurgery The University of Edinburgh Centre for Clinical Brain SciencesEdinburghUK Neurosurgery NHS LothianEdinburghUK Neurosurgery Institute of Neurological SciencesGlasgowUK Department of Medicine School of MedicineDentisty and NuringUniversity of GlasgowGlasgowUK Internal Medicine Queen's UniversityKingstonOntarioCanada Centre for Discovery Brain Sciences University of EdinburghEdinburghUK Edinburgh Centre for Diabetes and Endocrinology NHS LothianEdinburghUK Radiology University Hospitals Plymouth NHS TrustPlymouthUK Department of Medicine Cork University HospitalUniversity College CorkCorkIreland

Background Hyponatraemia often occurs after subarachnoid haemorrhage(SAH).However,its clinical significance and optimal management are *** audited the screening,investigation and management of hyponatraemia after *** We prospectively identified consecutive patients with spontaneous SAH admitted to neurosurgical units in the United Kingdom or *** reviewed medical records daily from admission to discharge,21 days or death and extracted all measurements of serum sodium to identify hyponatraemia(10 *** of hyponatraemia with outcome were assessed using logistic regression with adjustment for predictors of outcome after SAH and admission *** assessed hyponatraemia-free survival using multivariable Cox *** 175/407(43%)patients admitted to 24 neurosurgical units developed hyponatraemia.5976 serum sodium measurements were *** osmolality,urine osmolality and urine sodium were measured in 30/166(18%)hyponatraemic patients with complete *** most frequently target daily fluid intake was>3 L and this did not differ during hyponatraemic or non-hyponatraemic episodes.26%(n/N=42/164)patients with hyponatraemia received sodium supplementation.133(35%)patients were dead or dependent within the study period and 240(68%)patients had hospital admission for over 10 *** the multivariable analyses,hyponatraemia was associated with less dependency(adjusted OR(aOR)=0.35(95%CI 0.17 to 0.69))but longer admissions(aOR=3.2(1.8 to 5.7)).World Federation of Neurosurgical Societies grade I-III,modified Fisher 2-4 and posterior circulation aneurysms were associated with greater hazards of *** In this comprehensive multicentre prospective-adjusted analysis of patients with SAH,hyponatraemia was investigated inconsistently and,for most patients,was not associated with changes in management or clinical outcome.T

关键词： admitted urine centre

Patient selection essential in optimizing the benefit of radical prostatectomy for patients with organ-confined prostate cancer

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Asian journal of Andrology 2011年第6期13卷 789-790页

作者： Matthew j Resnick thomas j Guzzo The Division of Urology The Hospital of the University of Pennsylvania Philadelphia PA 19104 USA

P rostate cancer is the most common noncutaneous malignancy in the United States and is a highly prevalent disease worldwide in industrialized nations.1 Prostate cancer is also a leading cause of cancer related mortality in the United States with an estimated 32 050 deaths in 2010. If one were to simply look at the raw mortality data,

关键词： Prostate cancer noncutaneous appropriate treatment decisions

Neuromodulator interactions and spinal cord injury in lamprey

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Neural Regeneration Research 2018年第4期13卷 643-644页

作者： David Parker thomas j.McClelland Department of Physiology Neuroscience and DevelopmentUniversity of Cambridge

Neuromodulation is mediated by neurotransmitters that typically act on G-protein-coupled *** can confer behavioural flexibility by modifying the functional properties of anatomically hard-wired neural *** neuromodulators generally have divergent cellular and synaptic effects（Harris-Warrick and johnson,2010）,and different modulators,

关键词： Figure Neuromodulator interactions and spinal cord injury in lamprey

The role of polysulfide-saturation in electrolytes for high power applications of real world Li-S pouch cells

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Nano Research 2023年第6期16卷 8313-8320页

作者： Tom Boenke Sebastian Kirchhoff Florian SReuter Florian Schmidt Christine Weller Susanne Dörfler Kai Schwedtmann Paul Härtel thomas Abendroth Holger Althues jan j.Weig Stefan Kaskel Technische Universität Dresden Chair of Inorganic Chemistry IBergstr.6601069 DresdenGermany Fraunhofer Institute for Material and Beam Technology(IWS) Winterbergstr.2801277 DresdenGermany Technische Universität Dresden Chair of Inorganic Molecular ChemistryMommsenstraße 401069 DresdenGermany

The lithium-sulfur(Li-S)technology is the most promising candidate for next-generation batteries due to its high theoretical specific energy and steady progress for applications requiring lightweight batteries such as aviation or heavy electric *** these applications,however,the rate capability of Li-S cells requires significant *** electrolyte formulations in Li-S batteries enable new pathways for cell development and adjustment of all ***,their rate capability at pouch cell level is often neither evaluated nor compared to state of the art(SOTA)LiTFSI/dimethoxyethane/dioxolane(LITFSI:lithium-bis(trifluoromethylsulfonyl)imide)***,the combination of the sparingly polysulfide(PS)solvating hexylmethylether/1,2-dimethoxyethane(HME/DME)electrolyte and highly conductive carbon nanotube Buckypaper(CNT-BP)with low porosity was evaluated in both coin and pouch cells and compared to dimethoxyethane/dioxolane reference *** advanced sulfur transfer melt infiltration was employed for cathode production with *** Li+ion coordination in the HME/DME electrolyte was investigated by nuclear magnetic resonance(NMR)and Raman ***,ionic conductivity and viscosity was investigated for the pristine electrolyte and a polysulfide-statured *** electrolytes,DME/DOL-1/1(DOL:1,3-dioxolane)and HME/DME-8/2,are then combined with CNT-BP and transferred to multi-layered pouch *** study reveals that the ionic conductivity of the electrolyte increases drastically over state of(dis)charge especially for DME/DOL electrolyte and lean electrolyte regime leading to a better rate capability for the sparingly polysulfide solvating *** evaluation in prototype cells is an important step towards bespoke adaption of Li-S batteries for practical applications.

关键词： lithium-sulfur pouch cell polysulfide solubility electrolyte characterization high power

Higher cost of arthroplasty for hip fractures in patients transferred from outside hospitals vs primary emergency department presentation

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World journal of Orthopedics 2022年第8期13卷 725-732页

作者： Emanuel C Haug Hakan Pehlivan j Ryan Macdonell Wendy Novicoff james Browne thomas Brown Quanjun Cui Department of Orthopedic Surgery University of VirginiaCharlottesvilleVA 22908United States Department of Orthopedic Surgery Preferred Pediatric Orthopedic SurgeryRidgewoodNJ 07450United States Department of Orthopedic Surgery Asheville Orthopedic AssociatesAshevilleNC 28801United States

BACKGROUND In 2016 Centers for Medicare and Medicaid Services proposed bundled payments for hip fractures to improve the quality and decrease costs of *** transferred from other facilities may be imposing a financial risk on the hospitals that accept these *** To determine the costs associated with patients that either presented to the emergency department or were transferred from another hospital or skilled nursing facility(SNF)with the diagnosis of a hip fracture requiring operative *** A retrospective single institution review was conducted for all arthroplasty patients from 2010 to *** criteria included a total or partial hip replacement for a hip *** criteria included pathologic,periprosthetic,and fracture *** was collected to compare total observed costs for patients from the emergency department,patients from skilled nursing facilities,and patients from an outside *** A total of 223 patients met the inclusion criteria.135(60.54%)of these patients presented primarily to the emergency department,58 patients(26.01%)were transferred from an outside hospital,and 30 patients(13.43%)were transferred from a *** data analysis showed that outside hospital patients demonstrated significantly greater total cost for their hospitalization($43302)compared to emergency department patients($28875,P=0.000)and SNF patients($28282,P=0.000).CONCLUSION Patients transferred from an outside hospital incurred greater costs for their hospitalization than patients presenting from an emergency department or *** is a strong argument for riskadjustment models when bundling payments for the care of hip fracture patients.

关键词： Total hip arthroplasty Cost Transfer Outside hospital Hip fracture

A-posteriori error estimation for second order mechanical systems

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Acta Mechanica Sinica 2012年第3期28卷 854-862页

作者： thomas Ruiner jrg Fehr Bernard Haasdonk Peter Eberhard Institute of Engineering and Computational Mechanics University of StuttgartPfaffenwaldring 970569 StuttgartGermany Institute of Applied Analysis and Numerical Simulation University of StuttgartPfaffenwaldring 5770569 StuttgartGermany

One important issue for the simulation of flexible multibody systems is the reduction of the flexible bodies de- grees of freedom. As far as safety questions are concerned knowledge about the error introduced by the reduction of the flexible degrees of freedom is helpful and very important. In this work, an a-posteriori error estimator for linear first order systems is extended for error estimation of me- chanical second order systems. Due to the special second order structure of mechanical systems, an improvement of the a-posteriori error estimator is achieved. A major advan- tage of the a-posteriori error estimator is that the estimator is independent of the used reduction technique. Therefore, it can be used for moment-matching based, Gramian matrices based or modal based model reduction techniques. The capability of the proposed technique is demon- strated by the a-posteriori error estimation of a mechanical system, and a sensitivity analysis of the parameters involved in the error estimation process is conducted.

关键词： A-posteriori error estimator. Flexible multibodysystems Model reduction

Transjugular intrahepatic portosystemic shunt vs conservative treatment for recurrent ascites:A propensity score matched comparison

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World journal of Gastroenterology 2022年第41期28卷 5944-5956页

作者： Martin Philipp Theresia Blattmann jörn Bienert Kristian Fischer Luisa Hausberg jens-Christian Kröger thomas Heller Marc-AndréWeber Georg Lamprecht Department of Medicine Division of Gastroenterology and EndocrinologyRostock University Medical CenterRostock 18057Germany Institute of Diagnostic and Interventional Radiology Pediatric Radiology and NeuroradiologyRostock University Medical CentreRostock 18057Germany

BACKGROUND Transjugular intrahepatic portosystemic shunt(TIPS) placement is an effective intervention for recurrent tense ascites. Some studies show an increased risk of acute on chronic liver failure(ACLF) associated with TIPS placement. It is not clear whether ACLF in this context is a consequence of TIPS or of the pre-existing liver *** To better understand the risks of TIPS in this challenging setting and to compare them with those of conservative *** Two hundred and fourteen patients undergoing their first TIPS placement for recurrent tense ascites at our tertiary-care center between 2007 and 2017 were identified(TIPS group). Three hundred and ninety-eight patients of the same time interval with liver cirrhosis and recurrent tense ascites not undergoing TIPS placement(No TIPS group) were analyzed as a control group. TIPS indication,diagnosis of recurrent ascites, further diagnoses and clinical findings were obtained from a database search and patient records. The in-hospital mortality and ACLF incidence of both groups were compared using 1:1 propensity score matching and multivariate logistic *** After propensity score matching, the TIPS and No TIPS groups were comparable in terms of laboratory values and ACLF incidence at hospital admission. There was no detectable difference in mortality(TIPS: 11/214, No TIPS 13/214). During the hospital stay, ACLF occurred more frequently in the TIPS group than in the No TIPS group(TIPS: 70/214, No TIPS: 57/214, P = 0.04). This effect was confined to patients with severely impaired liver function at hospital admission as indicated by a significant interaction term of Child score and TIPS placement in multivariate logistic regression. The TIPS group had a lower ACLF incidence at Child scores < 8 points and a higher ACLF incidence at ≥ 11 points. No significant difference was found between groups in patients with Child scores of 8 to 10 *** TIPS placement for recurrent tense as

关键词： Liver cirrhosis Ascites Transjugular intrahepatic portosystemic shunt Acute on chronic liver failure Mortality Propensity score