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Application of Word Embedding to Drug Repositioning

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Journal of Biomedical Science and Engineering 2016年第1期9卷 7-16页

作者： Duc Luu Ngo Naoki Yamamoto Vu Anh tran ngoc Giang Nguyen Dau Phan Favorisen Rosyking Lumbanraja Mamoru Kubo Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

As a key technology of rapid and low-cost drug development, drug repositioning is getting popular. In this study, a text mining approach to the discovery of unknown drug-disease relation was tested. Using a word embedding algorithm, senses of over 1.7 million words were well represented in sufficiently short feature vectors. Through various analysis including clustering and classification, feasibility of our approach was tested. Finally, our trained classification model achieved 87.6% accuracy in the prediction of drug-disease relation in cancer treatment and succeeded in discovering novel drug-disease relations that were actually reported in recent studies.

关键词： Distributed Representation of Word Sense Discovery of Drug-Disease Relation Word Analogy

PHYSIOLOGICAL FUNCTIONS AND MOLECULAR MECHANISMS OF PROLACTIN IN ZEBRAFISH EMBRYOGENESIS

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PHYSIOLOGICAL FUNCTIONS AND MOLECULAR MECHANISMS OF PROLACTI...

DNA Sequence Classification by Convolutional Neural Network

国际比较生理生化及毒理学大会暨第六届中国比较生理学会议

作者： Nhu Nguyen ngoc-Tuyen T.tran Jennifer E.Rhinehart Susan M.Tobiasson Laboratory of Comparative Physiology and Molecular Endocrinology Department of BiologyEast Carolina UniversityGreenvilleNC 27858USA Laboratory of Comparative Physiology and Molecular Endocrinology Department of BiologyEast Carolina UniversityGreenvilleNC 27858USA Laboratory of Comparative Physiology and Molecular Endocrinology Department of BiologyEast Carolina UniversityGreenvilleNC 27858USA Laboratory of Comparative Physiology and Molecular Endocrinology Department of BiologyEast Carolina UniversityGreenvilleNC 27858USA

＜正＞The growth hormone（GH）and prolactin（PRL）superfamily,which includes the mammalian placental lactogen（PL）and teleost specific somatolactin（SL）,regulates tiunclreds of normal physiological and several disea...

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Journal of Biomedical Science and Engineering 2016年第5期9卷 280-286页

作者： ngoc Giang Nguyen Vu Anh tran Duc Luu Ngo Dau Phan Favorisen Rosyking Lumbanraja Mohammad Reza Faisal Bahriddin Abapihi Mamoru Kubo Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan

In recent years, a deep learning model called convolutional neural network with an ability of extracting features of high-level abstraction from minimum preprocessing data has been widely used. In this research, we proposed a new approach in classifying DNA sequences using the convolutional neural network while considering these sequences as text data. We used one-hot vectors to represent sequences as input to the model;therefore, it conserves the essential position information of each nucleotide in sequences. Using 12 DNA sequence datasets, we evaluated our proposed model and achieved significant improvements in all of these datasets. this result has shown a potential of using convolutional neural network for DNA sequence to solve other sequence problems in bioinformatics.

关键词： DNA Sequence Classification Deep Learning Convolutional Neural Network

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新时期的胡志明市城市规划——挑战与对策

上海城市规划 2017年第3期 77-82页

作者： Nguyen ngoc Hieu tran Hoang Nam 沙永杰张晓潇越南德国大学(VGU) 同济大学建筑与城市规划学院

胡志明市及周边区域正在快速发展,体现在经济、人口和城市规模等各个方面的快速增长,但在向城市群转型发展过程中,城市面临一系列新挑战,主要包括激烈的经济竞争、气候变化带来的威胁以及过去30年快速发展遗留和积累的问题等,这些促使... 详细信息

胡志明市及周边区域正在快速发展,体现在经济、人口和城市规模等各个方面的快速增长,但在向城市群转型发展过程中,城市面临一系列新挑战,主要包括激烈的经济竞争、气候变化带来的威胁以及过去30年快速发展遗留和积累的问题等,这些促使城市寻求新的可持续发展对策。本文介绍胡志明市城市发展与规划演变的历程,梳理胡志明市当前面临的五个方面的主要问题——城市发展模式、住房与城市贫民问题、交通、环境和区域之间合作,并进一步讨论面向未来的规划发展对策。

关键词：胡志明市城市规划与发展快速城市化气候变化城市群

固态发酵酶制剂充分释放水产饲料中潜在的营养物质

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饲料广角 2009年第1期 46-48页

作者： Le Thanh Huang tran ngoc thien Kim Alison Leary 越南Nong Lam大学水产系奥特奇亚太生物技术研究中心

1 前言亚太地区的水产养殖业面临许多挑战．饲料是人们关注的重点之一。饲料原料价格上涨．某些原料供应短缺以及质量降低已导致饲料原料市场的动荡和变化不定：植物蛋白原料已不再是笃定的饲料蛋白来源：生物燃料的乙醇工业与动物养殖... 详细信息

1 前言亚太地区的水产养殖业面临许多挑战．饲料是人们关注的重点之一。饲料原料价格上涨．某些原料供应短缺以及质量降低已导致饲料原料市场的动荡和变化不定：植物蛋白原料已不再是笃定的饲料蛋白来源：生物燃料的乙醇工业与动物养殖业竞争原料．已大大改变了饲料原料的成本结构。寻求可替代的饲料原料．饲料利用最佳化和动物生产最佳化的技术．以及减少营养物质排泄和减少饲料浪费的技术在当今的水产养殖和水产饲料配方中起着越来越重要的作用。

关键词：水产饲料营养物质固态发酵酶制剂水产养殖业饲料原料动物养殖业亚太地区

Feature Analysis and Classification of Particle Data from Two-Dimensional Video Disdrometer

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Advances in Remote Sensing 2015年第1期4卷 1-14页

作者： Sergey Gavrilov Mamoru Kubo Vu Anh tran Duc Luu Ngo ngoc Giang Nguyen Lan Anh T. Nguyen Favorisen Rosyking Lumbanraja Dau Phan Kenji Satou Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan Department of Computer Science Hue University of Education Hue Vietnam

We developed a ground observation system for solid precipitation using two-dimensional video disdrometer (2DVD). Among 16,010 particles observed by the system, around 10% of them were randomly sampled and manually classified into five classes which are snowflake, snowflake-like, intermediate, graupel-like, and graupel. At first, each particle was represented as a vector of 72 features containing fractal dimension and box-count to represent the complexity of particle shape. Feature analysis on the dataset clarified the importance of fractal dimension and box-count features for characterizing particles varying from snowflakes to graupels. On the other hand, performance evaluation of two-class classification by Support Vector Machine (SVM) was conducted. The experimental results revealed that, by selecting only 10 features out of 72, the average accuracy of classifying particles into snowflakes and graupels could reach around 95.4%, which had not been achieved by previous studies.

关键词： Solid Precipitation Particle Classification 2DVD Fractal Dimension PCA

Risk Management via Measuring Impacts of Micro and Macro Economic Factors on Financial Firm Stock Price—A Case of Mitsubishi UFJ in Japan

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Economics World 2020年第1期8卷 1-14页

作者： Dinh tran ngoc Huy Banking University HCM cityVietnam International University of Japan NiigataJapan

Mitsubishi UFJ(MUFJ)has made very positive contributions to the overall achievements of the banking industry,deserving its position as one of the leading financial groups in Japan,contributing to helping government stabilizes the market and successfully implement monetary *** is aiming for growth of approximately¥250 billion in net operating profits,with MUFG Group companies,business groups,and the corporate *** of stock price in financial groups such as MUFJ will reflect the business health of bank and financial system and the whole *** business management requires us to consider the impacts of multi micro and macro factors on stock price,and it contributes to promoting business plan and economic policies for economic growth and stabilizing macroeconomic *** data collection method through statistics,analysis,synthesis,comparison,quantitative analysis to generate qualitative comments and discussion;using econometric method to perform regression equation and evaluate quantitative results,the article analyzed and evaluated the impacts of six(6)micro and macro economic factors such as:cost,net sale,lending rate,inflation,GPD growth,S&P 500,*** stock price of a big financial group,MUFJ in Japan in the period of 2010-2019,both positive and negative *** results of quantitative research,in a seven-factor model,show that the decrease in inflation,GDP,and high lending rate has a significant effect on reducing MUFJ stock price with the highest impact coefficient,the second is increase in *** research finding and recommended policy also can be used as reference in policy for commercial bank and financial system in many developing countries.

关键词： MUFJ stock price GDP growth inflationary risk free rate market interest rate

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越南茶叶产业概况

中国茶叶 2012年第7期34卷 12-13页

作者： tran Xuan Hoang Do Van ngoc 房婉萍陈暄黎星辉南京农业大学茶叶科学研究所 210095 越南北方山区农林业技术科学院越南茶叶研究所

越南是典型的农业国家，农业人口占总人口的76％。近年来，越南茶叶发展很快，引起业界重视。应越南国家茶叶研究机构——越南北方山区农林业技术科学院的邀请，南京农业大学组团于2011年赴越南联合开展了越南茶叶生产状况的中越合作考... 详细信息

越南是典型的农业国家，农业人口占总人口的76％。近年来，越南茶叶发展很快，引起业界重视。应越南国家茶叶研究机构——越南北方山区农林业技术科学院的邀请，南京农业大学组团于2011年赴越南联合开展了越南茶叶生产状况的中越合作考察，现将越南茶叶产业概况简要介绍如下。

关键词：茶叶发展产业概况越南南京农业大学农业人口林业技术北方山区研究机构

亚热带多雨区生态护岸结构与效能研究——以荣市前门河道为例

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黑龙江生态工程职业学院学报 2016年第6期29卷 9-11,119页

作者： Tang Van Tai 李奎鹏 tran ngoc Binh Nguyen Nhu Anh 东南大学土木工程学院江苏南京210096 烟台市水利建筑勘察设计院山东烟台264001 越南荣市医学大学越南建设公司

传统护岸工程大量使用浆砌石、钢筋混凝土等材料建造成直立式结构,给河流水环境、生物群落等带来了诸多不利影响。以越南荣市的前门河道为研究对象,针对前门河道的水生态特征与河道岸边环境、土壤条件,设计并建造了抛石型和石笼型两种... 详细信息

传统护岸工程大量使用浆砌石、钢筋混凝土等材料建造成直立式结构,给河流水环境、生物群落等带来了诸多不利影响。以越南荣市的前门河道为研究对象,针对前门河道的水生态特征与河道岸边环境、土壤条件,设计并建造了抛石型和石笼型两种生态护岸形式。通过为期1年的香根草生长状况跟踪监测,提出了一种适用于亚热带多雨区的生态护岸植被,通过Miseq高通量测序实验测定了生态护岸微生物群落多样性,揭示了其生态净水机理。

关键词：生态护岸抛石护岸石笼护岸香根草