DNA Sequence Classification by Convolutional Neural Network

作     者：Ngoc Giang Nguyen Vu Anh Tran Duc Luu Ngo Dau Phan Favorisen Rosyking Lumbanraja Mohammad Reza Faisal Bahriddin Abapihi Mamoru Kubo Kenji Satou Ngoc Giang Nguyen;Vu Anh Tran;Duc Luu Ngo;Dau Phan;Favorisen Rosyking Lumbanraja;Mohammad Reza Faisal;Bahriddin Abapihi;Mamoru Kubo;Kenji Satou

作者机构：Graduate School of Natural Science and Technology Kanazawa University Kanazawa Japan Institute of Science and Engineering Kanazawa University Kanazawa Japan 

出 版 物：《Journal of Biomedical Science and Engineering》 (生物医学工程（英文）)

年 卷 期：2016年第9卷第5期

页      面：280-286页

学科分类：08[工学] 0812[工学-计算机科学与技术（可授工学、理学学位）] 

主　　题：DNA Sequence Classification Deep Learning Convolutional Neural Network 

摘      要：In recent years, a deep learning model called convolutional neural network with an ability of extracting features of high-level abstraction from minimum preprocessing data has been widely used. In this research, we proposed a new approach in classifying DNA sequences using the convolutional neural network while considering these sequences as text data. We used one-hot vectors to represent sequences as input to the model;therefore, it conserves the essential position information of each nucleotide in sequences. Using 12 DNA sequence datasets, we evaluated our proposed model and achieved significant improvements in all of these datasets. This result has shown a potential of using convolutional neural network for DNA sequence to solve other sequence problems in bioinformatics.