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双渠道多级分销网络库存整合优化配置

工业工程 2021年第4期24卷 134-142页

作者：林瀚盛屈挺徐素秀 thürer matthias 郭洪飞黄国全暨南大学管理学院广东广州510632 暨南大学智能科学与工程学院广东珠海519070 暨南大学物联网研究院广东珠海519070 香港大学工业与制造系统工程系中国香港999077

针对拥有线下、线上销售渠道的实体零售企业分销网络运作成本居高不下的现状,研究综合渠道整合和线上订单履行问题下的双渠道库存优化配置问题。在“双渠道库存独立管理、线上订单分散履行”和“双渠道库存整合管理、线上订单集中履行”... 详细信息

针对拥有线下、线上销售渠道的实体零售企业分销网络运作成本居高不下的现状,研究综合渠道整合和线上订单履行问题下的双渠道库存优化配置问题。在“双渠道库存独立管理、线上订单分散履行”和“双渠道库存整合管理、线上订单集中履行”2种不同分销网络运作模式下分别建立数学模型,并利用基于实数编码的遗传算法进行求解。通过对比这2种不同运作模式下的运作成本,同时在需求波动率增加条件下对运作成本进行敏感性分析,发现渠道库存整合、线上订单集中履行方法能够将库存总费用降低17.25%,能够将库存总费用从中下游往上游转移,减缓中下游节点的库存总费用。

关键词：库存优化配置渠道整合线上订单履行

Pressure and temperature effects resulting from impact onto materials of different reactivity

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Defence Technology(防务技术) 2025年第2期44卷 221-230页

作者： Andreas Heine matthias Wickert Fraunhofer Institute for High-Speed Dynamics Ernst-Mach-InstitutEMIErnst-Zermelo-Str.4Freiburg im Breisgau79104Germany

the pressure and temperature increase resulting from the impact of different threats onto target materials is analyzed with a unified laboratory-scale *** allows deriving qualitative information on the occurring phenomenology as well as quantitative statements about the relative effects sizes as a function of target material and *** considered target materials are steel,aluminum,and *** threats,kinetic energy penetrator,explosively formed projectile,and shaped charge jet are *** the investigated combinations,the measured overpressures vary by a factor of up to 5 for a variation of the material,by a factor of up to 7 for a variation of the threat,and by a factor larger than 15for a simultaneous variation of *** obtained results as well as the experimental approach are relevant for the basic understanding of impact effects and risks due to material *** paper combines two main ***,to provide a summary of own prior work in a coherent journal article and,secondly,to review and discuss these earlier results with a new perspective.

关键词： Impact effects Pressure Temperature Risk assessment Material reactivity

Rule based vs Optimization based Workload Control with and without Exogenous Lead Times:An Assessment by Simulation

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Journal of Systems Science and Systems Engineering 2023年第5期32卷 553-570页

作者： Mingze Yuan Ting Qu matthias thürer Lin Ma Lei Liu School of Management Jinan UniversityGuangzhou510632China GBA and B&R International Joint Research Center for Smart Logistics Jinan UniversityZhuhai519070China School of Intelligent Systems Science and Engineering Jinan UniversityZhuhai519070China Institute of Physical Internet Jinan UniversityZhuhai519070China Factory Planning and Intralogistics Chemnitz University of TechnologyChemnitz09125Germany Department of Industrial and Systems Engineering The Hong Kong Polytechnic UniversityHong Kong999077China

Order release is a key production planning and control function,specifically in high variety contexts.A large literature on release methods that balance the workload consequently *** Workload Control methods can be rule based,using a simple greedy heuristic,optimization based or optimization based with lead times that are *** all three types of methods have the same objective,their performance has never been *** simulation,this study shows that a better on time delivery performance of jobs can be achieved by the two optimization based release *** importantly,optimization based methods that assume lead times to be exogenous significantly outperform alternative methods in terms of tardiness *** based and optimization based Workload Control without exogenous lead times overemphasize average lateness reduction,which leads to sequence deviations that offset performance improvements through *** contrast,Workload Control methods that assume lead times to be exogenous limit sequence deviations,which leads to a significant reduction in dispersion of *** has important implication for the future design of order release methods,and managerial practice.

关键词： Workload control order release production planning production control make-to-order production

Small extrachromosomal circular DNA in amyotrophic lateral sclerosis matter

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Neural Regeneration Research 2025年第5期20卷 1411-1413页

作者： Marcos J.Arauzo-Bravo Daniela Gerovska matthias Schwab Alexandra Kretz Computational Biology and Systems Biomedicine Biodonostia Health Research InstituteSan SebastianSpain Basque Foundation for Science IKERBASQUEBilbaoSpainMax Planck Institute for Molecular BiomedicineComputational Biology and Bioinformatics GroupMünsterNorth Rhine-WestphaliaGermany Department of Cell Biology and Histology Faculty of Medicine and NursingUniversity of Basque Country(UPV/EHU)LeioaSpain Department of Neurology Jena University HospitalJenaThuringiaGermany

Comprehensive studies identify motor neuron spectrum disorders including amyotrophic lateral sclerosis(ALS)as globally rising fatal disorders with the highest prevalence in aging populations,influenced by ethnicity and ancestry(GBD 2016 Motor Neuron Disease Colla borators,2018).While~10% of diagnoses involve a family history(fALS),most cases are considered sporadic(sALS).However,population-based studies suggest that even cases without a common index mutation impart heritability(Ryan et al.,2019),indicating a crucial role of rare and as yet unknown genetic denominators.

关键词： amyotrophic sclerosis

Adnexal Sliding Hernia in an Infant: Clinical-Anatomical Case Report

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Open Journal of Pediatrics 2025年第1期15卷 93-100页

作者： Ralf-Bodo Tröbs Grigore Cernaianu matthias Nissen Department of General Visceral and Pediatric Surgery St. Vincenz Hopitals Paderborn Germany Division of Pediatric Surgery University Hospital Cologne Cologne Germany Department of Pediatric Surgery St. Maries Hospital Witten Ruhr-University of Bochum Sankt Elisabeth Gruppe Germany

We present a case report of laparoscopic herniorrhaphy in an infant with ovarian prolapse. Using this case study, we demonstrate the role of the ovarian ligamentous apparatus. A structure appearing like the male gubernaculum was identified. the anatomical and functional role of this “gubernaculum” will be the subject of discussion. Further detailed laparoscopic examinations are indicated to better understand the ligamentous anatomy of ovarian prolapse.

关键词： Inguinal Hernia Ovarian Prolapse Ovarian Descensus Sliding Hernia Gubernaculum

the Potential of Wacapou (Vouacapoua americana) Extracts to Develop New Biobased Protective Solutions for Low-Durability Wood Species

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Journal of Renewable Materials 2025年第1期13卷 79-100页

作者： Emma Kieny Kévin Candelier Louis Milhe Yannick Estevez Cyrielle Sophie Romain Lehnebach Jérémie Damay Daniela Florez Emeline Houël Marie-France thévenon Julie Bossu CIRAD Ecologie de Forêts de Guyane(EcoFoG)AgroparisTechCNRSINRAEUniversitéde GuyaneKourou97379France CIRAD UPR BioWooEBMontpellierF-34398France BioWooEB Universitéde MontpellierCIRADMontpellierF-34398France CNRS Ecologie de Forêts de Guyane(EcoFoG)AgroparisTechCIRADINRAEUniversitéde GuyaneKourouGuyane Française97379France Sorbonne Université CNRSLaboratoire de Biodiversitéet Biotechnologies MicrobiennesLBBMObservatoire OcéanologiqueBanyuls-sur-Mer66650France

the valorization of Amazonian wood residues into active chemical compounds could be an eco-friendly,cost-effective and valuable way to develop wood preservative formulations to enhance the decay and termite resistance of low-durable wood ***(Vouacapoua americana.,Fabaceae)is a well-known Guianese wood spe-cies commonly used in local wood construction due to its outstanding natural durability,which results from the presence of a large panel of extractives *** addition,its industrial processing generates large amounts of *** residues were extracted by maceration using four different solvents(water/ethanol,ethyl acetate,hexane and dichloromethane/methanol),separately and *** yield of each extractive fraction was determined,and their chemical compositions were analyzed by Liquid Chromatography-Mass Spectrometry(LC-MS).Ethyl acetate led to the highest extraction yield,and the active compounds were identiﬁed in the obtained extractive *** this sense,the fungicidal and termite-repellent properties of these extractives were then tested using a screening laboratory(with temperate and tropical microorganisms),according to the solution concentration(1%,2.5%,5%,8%and 10%).Finally,Virola michelii Heckel wood samples(low durable species)were impregnated with the 8%concentration *** impregnated wood samples were then exposed to a soil bed *** results highlighted that the nature of the solvent used during wood maceration affects the con-tent of the obtained extractive ***-Performance Liquid Chromatography–High-Resolution Mass Spectrometry(UHPLC-HRMS)analyses showed the inﬂuence of extraction parameters on the nature of the extracted *** extracts(from ethyl acetate maceration)showed good anti-fungal and anti-termite ***,the concentration in extractives had an impact on the anti-termite activity level for Reti-culitermesﬂavipes and Cryptotermes *** based on W

关键词： Anti-fungal and anti-termite activities conferred durability extractives French Guiana impregnation guianese species wood by-products

A Critical Review of Methods and Challenges in Large Language Models

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Computers, Materials & Continua 2025年第2期82卷 1681-1698页

作者： Milad Moradi Ke Yan David Colwell matthias Samwald Rhona Asgari AI Research TricentisVienna1220Austria AI Research TricentisSydneyNSW 2010Australia Institute of Artificial Intelligence Center for Medical StatisticsInformaticsand Intelligent SystemsMedical University of ViennaVienna1090Austria

this critical review provides an in-depth analysis of Large Language Models(LLMs),encompassing their foundational principles,diverse applications,and advanced training *** critically examine the evolution from Recurrent Neural Networks(RNNs)to Transformer models,highlighting the significant advancements and innovations in LLM *** review explores state-of-the-art techniques such as in-context learning and various fine-tuning approaches,with an emphasis on optimizing parameter *** also discuss methods for aligning LLMs with human preferences,including reinforcement learning frameworks and human feedback *** emerging technique of retrieval-augmented generation,which integrates external knowledge into LLMs,is also ***,we address the ethical considerations of deploying LLMs,stressing the importance of responsible and mindful *** identifying current gaps and suggesting future research directions,this review provides a comprehensive and critical overview of the present state and potential advancements in *** work serves as an insightful guide for researchers and practitioners in artificial intelligence,offering a unified perspective on the strengths,limitations,and future prospects of LLMs.

关键词： Large language models artificial intelligence natural language processing machine learning generative artificial intelligence

Investigating Biological Relationships in Burkina Faso Using DNA Testing

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American Journal of Molecular Biology 2025年第1期15卷 97-109页

作者： Bapio Valérie Elvira Jean Télesphore Bazie Moussa Ouattara Serge théophile Soubeiga Abdou Azaque Zoure Prosper Bado Abel Sorgho Touwendpoulimdé Isabelle Kiendrebeogo Lassina Traore Soumaïla Sawadogo Luc Zongo théodora M. Zohoncon Florencia W. Djigma théophane Albert T. Yonli Mahamoudou Sanou Jacques Simpore Centre de Recherche Biomolculaire Pietro Annigoni (CERBA) Ouagadougou Burkina Faso Universit Joseph KI-ZERBO Unit de Formation en Sciences de la Vie et de la Terre Laboratoire de Biologie Molculaire et de Gntique (LABIOGENE) Ouagadougou Burkina Faso Centre National de la Recherche Scientifique et Technologique (CNRST) Institut de Recherche en Sciences de la Sant (IRSS) Ouagadougou Burkina Faso Faculty of Health Sciences University Saint Thomas dAquin (USTA) Ouagadougou Burkina Faso Centre Hospitalier Universitaire Pdiatrie Charles De Gaulle Universit Joseph Ki-Zerbo Ouagadougou Burkina Faso

DNA testing for biological relationships is becoming increasingly common in Burkina Faso. STR analysis remains the most reliable technique for resolving disputes or claims in court regarding biological relationships. this study aimed to establish the links of biological relationships between subjects by analyzing 21 STR loci. the participants were 14 individuals referred to CERBA by the Justice in 2022. Oral or blood samples were taken for each subject. DNA was extracted, and the analysis of DNA polymorphism by PowerPlex® 21 Kit (Part No. DC8902) was performed by capillary electrophoresis on the ABI PRISM 3130 sequencer. DNA profiles were compiled using the GeneMapper IDX software version 1.2. Of the fourteen subjects examined, twelve of these samples had complete genetic profiles, while the other two had partial and absent profiles. the results confirmed the inclusion of three cases of Paternity, one case of maternity, one case of a relationship of brotherhood, and the exclusion of one case of maternity and one case of a relationship of brotherhood. DNA tests improve the resolution of filiations, but they require ethical and cultural awareness and a strengthened legal framework to prevent and protect society.

关键词： DNA STR Identification Genetic Fingerprint Burkina Faso

Evaluation of Diagnostic Performance of a Multiplex RT-qPCR Method for Detecting DENV Serotypes and CHIKV in Clinical Samples, Ouagadougou, Burkina Faso

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Journal of Biosciences and Medicines 2025年第1期13卷 13-20页

作者： Michel Kiréopori Gomgnimbou Louis Robert W. Belem Boukandou Passi L. Mongo Shoukrat O. T. Bello Armel Moumouni Sanou Albert théophane Yonli théodora Mahoukèdè Zohoncon Jacques Simpore Equipe Biologie Molculaire et Biotechnologies Laboratoire de Recherche Centre MURAZ Institut National de Sant Publique Bobo-Dioulasso Burkina Faso Centre dExcellence Africain en Innovations Biotechnologiques pour lElimination des Maladies Transmission Vectorielle (CEA/ITECH-MTV) Universit Nazi BONI Bobo-Dioulasso Burkina Faso Institut Suprieur des Sciences de la Sant (IN.S.SA) Universit Nazi BONI Bobo-Dioulasso Burkina Faso Centre de Recherche Biomolculaire Pietro Annigoni (CERBA) Ouagadougou Burkina Faso Laboratoire de Recherche sur les Maladies Infectieuses et Parasitaire (LR-MIP) Institut de Recherche en Science de la Sante Bobo-Dioulasso Burkina Faso Laboratoire de Biologie Molculaire et de Gntique (LABIOGENE) UFR/SVT Universit Joseph Ki-Zerbo Ouagadougou Burkina Faso Facult de Mdecine Universit Saint Thomas dAquin (USTA) Ouagadougou Burkina Faso

Introduction: Arbovirus diseases such as dengue and chikungunya threaten public health worldwide. Early and rapid diagnosis and surveillance of dengue virus (DENV) and chikungunya virus (CHIKV) infections are essential to the control of these diseases. In this study, we evaluate the diagnostic performance of our new in-house multiplex RT-qPCR method for detecting DENV serotypes and CHIKV in an external laboratory. Methodology: the evaluation study was conducted on 200 clinical samples of suspected patients for arbovirus disease infection, collected in Centre de Recherche Biomoléculaire Pietro Annigoni (CERBA), Ouagadougou, Burkina Faso. Our new multiplex RT-qPCR was compared to the commercial kit, the Zika, Dengue, and Chikungunya (ZDC) Real-Time PCR Assays kit (Bio-Rad, California, USA). Results and Conclusions: Among 200 samples, 21.5% (43/200) were DENV-positive by multiplex RT-qPCR, and 21.5% (43/200) were also DENV-positive by reference real-time RT-PCR. 157 (78.5%) samples tested negative for DENV by both tests (new mRT-qPCR and reference test). the sensitivity and specificity of mRT-qPCR were 100%. the DENV serotypes detected were DENV-1 60.5% (26/43) and DENV-3 39.5% (17/43). CHIKV was not detected in this study. Our new mRT-qPCR is sensitive, cost-effective, simple, and can be used in developing country laboratories.

关键词： Evaluation Multiplex RT-qPCR Dengue Virus Chikungunya Burkina Faso